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2021 Journal Article Novel neurotoxic activity in Calliophis intestinalis venomDashevsky, Daniel, Deuis, Jennifer R., Vetter, Irina, Huynh, Tam, Hodgson, Wayne C., Tan, Choo Hock, Nouwens, Amanda and Fry, Bryan G. (2021). Novel neurotoxic activity in Calliophis intestinalis venom. Neurotoxicity Research, 40 (1), 173-178. doi: 10.1007/s12640-021-00413-2 |
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2021 Journal Article An ultrapotent and selective cyclic peptide inhibitor of human β-factor XIIa in a cyclotide scaffoldLiu, Wenyu, de Veer, Simon J., Huang, Yen-Hua, Sengoku, Toru, Okada, Chikako, Ogata, Kazuhiro, Zdenek, Christina N., Fry, Bryan G., Swedberg, Joakim E., Passioura, Toby, Craik, David J. and Suga, Hiroaki (2021). An ultrapotent and selective cyclic peptide inhibitor of human β-factor XIIa in a cyclotide scaffold. Journal of the American Chemical Society, 143 (44) jacs.1c07574, 18481-18489. doi: 10.1021/jacs.1c07574 |
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2021 Journal Article The Relative Efficacy of Chemically Diverse Small-Molecule Enzyme-Inhibitors Against Anticoagulant Activities of African Spitting Cobra (Naja Species) VenomsChowdhury, Abhinandan, Lewin, Matthew R., Zdenek, Christina N., Carter, Rebecca and Fry, Bryan G. (2021). The Relative Efficacy of Chemically Diverse Small-Molecule Enzyme-Inhibitors Against Anticoagulant Activities of African Spitting Cobra (Naja Species) Venoms. Frontiers in Immunology, 12 752442, 1-9. doi: 10.3389/fimmu.2021.752442 |
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2021 Journal Article Clinical implications of ontogenetic differences in the coagulotoxic activity of Bothrops jararacussu venomsBittencourt Rodrigues, Caroline Fabri, Zdenek, Christina N., Bourke, Lachlan A., Seneci, Lorenzo, Chowdhury, Abhinandan, Freitas-de-Sousa, Luciana Aparecida, de Alcantara Menezes, Frederico, Moura-da-Silva, Ana Maria, Tanaka-Azevedo, Anita Mitico and Fry, Bryan G. (2021). Clinical implications of ontogenetic differences in the coagulotoxic activity of Bothrops jararacussu venoms. Toxicology Letters, 348, 59-72. doi: 10.1016/j.toxlet.2021.05.005 |
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2021 Journal Article Evidence for resistance to coagulotoxic effects of Australian elapid snake venoms by sympatric prey (blue tongue skinks) but not by predators (monitor lizards)Youngman, Nicholas J., Llinas, Joshua and Fry, Bryan G. (2021). Evidence for resistance to coagulotoxic effects of Australian elapid snake venoms by sympatric prey (blue tongue skinks) but not by predators (monitor lizards). Toxins, 13 (9) 590, 590. doi: 10.3390/toxins13090590 |
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2021 Journal Article The dragon’s paralysing spell: evidence of sodium and calcium ion channel binding neurotoxins in helodermatid and varanid lizard venomsDobson, James S., Harris, Richard J., Zdenek, Christina N., Huynh, Tam, Hodgson, Wayne C., Bosmans, Frank, Fourmy, Rudy, Violette, Aude and Fry, Bryan G. (2021). The dragon’s paralysing spell: evidence of sodium and calcium ion channel binding neurotoxins in helodermatid and varanid lizard venoms. Toxins, 13 (8) 549, 1-14. doi: 10.3390/toxins13080549 |
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2021 Journal Article A symphony of destruction: dynamic differential fibrinogenolytic toxicity by rattlesnake (Crotalus and Sistrurus) venomsSeneci, Lorenzo, Zdenek, Christina N., Bourke, Lachlan A., Cochran, Chip, Sánchez, Elda E., Neri-Castro, Edgar, Bénard-Valle, Melisa, Alagón, Alejandro, Frank, Nathaniel and Fry, Bryan G. (2021). A symphony of destruction: dynamic differential fibrinogenolytic toxicity by rattlesnake (Crotalus and Sistrurus) venoms. Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology, 245 109034, 109034. doi: 10.1016/j.cbpc.2021.109034 |
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2021 Journal Article Pharmacological characterisation of Pseudocerastes and Eristicophis viper venoms reveal anticancer (melanoma) properties and a potentially novel mode of fibrinogenolysisop den Brouw, Bianca, Ghezellou, Parviz, Casewell, Nicholas R., Ali, Syed Abid, Fathinia, Behzad, Fry, Bryan G., Bos, Mettine H.A. and Ikonomopoulou, Maria P. (2021). Pharmacological characterisation of Pseudocerastes and Eristicophis viper venoms reveal anticancer (melanoma) properties and a potentially novel mode of fibrinogenolysis. International Journal of Molecular Sciences, 22 (13) 6896, 1-17. doi: 10.3390/ijms22136896 |
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2021 Journal Article Editorial: venoms and toxins: at the crossroads of basic, applied and clinical immunologyPucca, Manuela B., Fry, Bryan G., Sartim, Marco A., Peigneur, Steve and Monteiro, Wuelton M. (2021). Editorial: venoms and toxins: at the crossroads of basic, applied and clinical immunology. Frontiers in Immunology, 12 716508, 716508. doi: 10.3389/fimmu.2021.716508 |
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2021 Journal Article Venom-induced blood disturbances by palearctic viperid snakes, and their relative neutralization by antivenoms and enzyme-inhibitorsChowdhury, Abhinandan, Zdenek, Christina N., Lewin, Matthew R., Carter, Rebecca, Jagar, Tomaž, Ostanek, Erika, Harjen, Hannah, Aldridge, Matt, Soria, Raul, Haw, Grace and Fry, Bryan G. (2021). Venom-induced blood disturbances by palearctic viperid snakes, and their relative neutralization by antivenoms and enzyme-inhibitors. Frontiers in Immunology, 12 688802, 688802. doi: 10.3389/fimmu.2021.688802 |
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2021 Journal Article Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulneransWalker, Andrew A., Robinson, Samuel D., Paluzzi, Jean-Paul V., Merritt, David J., Nixon, Samantha A., Schroeder, Christina I., Jin, Jiayi, Goudarzi, Mohaddeseh Hedayati, Kotze, Andrew C., Dekan, Zoltan, Sombke, Andy, Alewood, Paul F., Fry, Bryan G., Epstein, Marc E., Vetter, Irina and King, Glenn F. (2021). Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans. Proceedings of the National Academy of Sciences of the United States of America, 118 (18) 2023815118, e2023815118. doi: 10.1073/pnas.2023815118 |
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2021 Journal Article Clinical implications of differential procoagulant toxicity of the palearctic viperid genus Macrovipera, and the relative neutralization efficacy of antivenoms and enzyme inhibitorsChowdhury, Abhinandan, Zdenek, Christina N., Dobson, James S., Bourke, Lachlan A., Soria, Raul and Fry, Bryan G. (2021). Clinical implications of differential procoagulant toxicity of the palearctic viperid genus Macrovipera, and the relative neutralization efficacy of antivenoms and enzyme inhibitors. Toxicology Letters, 340, 77-88. doi: 10.1016/j.toxlet.2020.12.019 |
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2021 Journal Article Getting stoned: Characterisation of the coagulotoxic and neurotoxic effects of reef stonefish (Synanceia verrucosa) venomHarris, Richard J., Youngman, Nicholas J., Chan, Weili, Bosmans, Frank, Cheney, Karen L. and Fry, Bryan G. (2021). Getting stoned: Characterisation of the coagulotoxic and neurotoxic effects of reef stonefish (Synanceia verrucosa) venom. Toxicology Letters, 346, 16-22. doi: 10.1016/j.toxlet.2021.04.007 |
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2021 Journal Article Not Goanna Get Me: Mutations in the Savannah Monitor Lizard (Varanus exanthematicus) nicotinic acetylcholine receptor confer reduced susceptibility to sympatric cobra venomsJones, Lee, Harris, Richard J. and Fry, Bryan G. (2021). Not Goanna Get Me: Mutations in the Savannah Monitor Lizard (Varanus exanthematicus) nicotinic acetylcholine receptor confer reduced susceptibility to sympatric cobra venoms. Neurotoxicity Research, 39 (4), 1116-1122. doi: 10.1007/s12640-021-00351-z |
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2021 Journal Article A clot twist: extreme variation in coagulotoxicity mechanisms in Mexican neotropical rattlesnake venomsSeneci, Lorenzo, Zdenek, Christina N., Chowdhury, Abhinandan, Rodrigues, Caroline F. B., Neri-Castro, Edgar, Benard-Valle, Melisa, Alagon, Alejandro and Fry, Bryan G. (2021). A clot twist: extreme variation in coagulotoxicity mechanisms in Mexican neotropical rattlesnake venoms. Frontiers in Immunology, 12 612846, 612846. doi: 10.3389/fimmu.2021.612846 |
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2021 Journal Article ERK and mTORC1 inhibitors enhance the anti-cancer capacity of the octpep-1 venom-derived peptide in melanoma BRAF(V600E) mutationsMoral-Sanz, Javier, Fernandez-Rojo, Manuel A., Potriquet, Jeremy, Mukhopadhyay, Pamela, Brust, Andreas, Wilhelm, Patrick, Smallwood, Taylor B., Clark, Richard J., Fry, Bryan G., Alewood, Paul F., Waddell, Nicola, Miles, John J., Mulvenna, Jason P. and Ikonomopoulou, Maria P. (2021). ERK and mTORC1 inhibitors enhance the anti-cancer capacity of the octpep-1 venom-derived peptide in melanoma BRAF(V600E) mutations. Toxins, 13 (2) 146, 1-19. doi: 10.3390/toxins13020146 |
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2021 Journal Article Electric blue: molecular evolution of three-finger toxins in the long-glanded coral snake species Calliophis bivirgatusDashevsky, Daniel, Rokyta, Darin, Frank, Nathaniel, Nouwens, Amanda and Fry, Bryan G. (2021). Electric blue: molecular evolution of three-finger toxins in the long-glanded coral snake species Calliophis bivirgatus. Toxins, 13 (2) 124, 1-16. doi: 10.3390/toxins13020124 |
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2021 Journal Article Extensive variation in the activities of Pseudocerastes and Eristicophis viper venoms suggests divergent envenoming strategies are used for prey captureop den Brouw, Bianca, Coimbra, Francisco C. P., Bourke, Lachlan A., Huynh, Tam Minh, Vlecken, Danielle H. W., Ghezellou, Parviz, Visser, Jeroen C., Dobson, James S., Fernandez-Rojo, Manuel A., Ikonomopoulou, Maria P., Casewell, Nicholas R., Ali, Syed A., Fathinia, Behzad, Hodgson, Wayne C. and Fry, Bryan G. (2021). Extensive variation in the activities of Pseudocerastes and Eristicophis viper venoms suggests divergent envenoming strategies are used for prey capture. Toxins, 13 (2) 112, 1-21. doi: 10.3390/toxins13020112 |
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2021 Journal Article Anticoagulant Micrurus venoms: targets and neutralizationDashevsky, Daniel, Benard-Valle, Melisa, Neri-Castro, Edgar, Youngman, Nicholas J., Zdenek, Christina N., Alagon, Alejandro, Portes-Junior, Jose A., Frank, Nathaniel and Fry, Bryan G. (2021). Anticoagulant Micrurus venoms: targets and neutralization. Toxicology Letters, 337, 91-97. doi: 10.1016/j.toxlet.2020.11.010 |
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2021 Journal Article Utilising venom activity to infer dietary composition of the Kenyan horned viper (Bitis worthingtoni)Youngman, Nicholas J., Chowdhury, Abhinandan, Zdenek, Christina N., Coster, Kristian, Sundman, Eric, Braun, Ralph and Fry, Bryan G. (2021). Utilising venom activity to infer dietary composition of the Kenyan horned viper (Bitis worthingtoni). Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology, 240 108921, 108921. doi: 10.1016/j.cbpc.2020.108921 |