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2018

Journal Article

Efficacy and safety of methionine aminopeptidase 2 inhibition in type 2 diabetes: a randomised, placebo-controlled clinical trial

Proietto, Joseph, Malloy, Jaret, Zhuang, Dongliang, Arya, Mark, Cohen, Neale D., de Looze, Ferdinandus J., Gilfillan, Christopher, Griffin, Paul, Hall, Stephen, Nathow, Thomas, Oldfield, Geoffrey S., O'Neal, David N., Roberts, Adam, Stuckey, Bronwyn G. A., Yue, Dennis, Taylor, Kristin and Kim, Dennis (2018). Efficacy and safety of methionine aminopeptidase 2 inhibition in type 2 diabetes: a randomised, placebo-controlled clinical trial. Diabetologia, 61 (9), 1918-1922. doi: 10.1007/s00125-018-4677-0

Efficacy and safety of methionine aminopeptidase 2 inhibition in type 2 diabetes: a randomised, placebo-controlled clinical trial

2018

Journal Article

Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial

Sekuloski, Silvana, Batzloff, Michael R., Griffin, Paul, Parsonage, William, Elliott, Suzanne, Hartas, Jon, O'Rourke, Peter, Marquart, Louise, Pandey, Manisha, Rubin, Fran A., Carapetis, Jonathan, McCarthy, James and Good, Michael F. (2018). Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial. PLoS One, 13 (7) e0198658, e0198658. doi: 10.1371/journal.pone.0198658

Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial

2018

Journal Article

Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatch™)

Fernando, Germain J. P., Hickling, Julian, Jayashi Flores, Cesar M., Griffin, Paul, Anderson, Christopher D., Skinner, S. Rachel, Davies, Cristyn, Witham, Katey, Pryor, Melinda, Bodle, Jesse, Rockman, Steve, Frazer, Ian H. and Forster, Angus H. (2018). Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatch™). Vaccine, 36 (26), 3779-3788. doi: 10.1016/j.vaccine.2018.05.053

Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatch™)

2018

Journal Article

The Dynamics of Liver Function Test Abnormalities after Malaria Infection: A Retrospective Observational Study

Woodford, John, Shanks, G Dennis, Griffin, Paul, Chalon, Stephan and McCarthy, James (2018). The Dynamics of Liver Function Test Abnormalities after Malaria Infection: A Retrospective Observational Study. The American Journal of Tropical Medicine and Hygiene, 98 (4), 1113-1119. doi: 10.4269/ajtmh.17-0754

The Dynamics of Liver Function Test Abnormalities after Malaria Infection: A Retrospective Observational Study

2017

Journal Article

Safety, acceptability and tolerability of uncoated and excipient-coated high density silicon micro-projection array patches in human subjects

Griffin, Paul, Elliot, Suzanne, Krauer, Kenia, Davies, Cristyn, Skinner, Rachel, Anderson, Christopher D. and Forster, Anguis (2017). Safety, acceptability and tolerability of uncoated and excipient-coated high density silicon micro-projection array patches in human subjects. Vaccine, 35 (48), 6676-6684. doi: 10.1016/j.vaccine.2017.10.021

Safety, acceptability and tolerability of uncoated and excipient-coated high density silicon micro-projection array patches in human subjects

2017

Journal Article

Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study

McCarthy, James S., Lotharius, Julie, Ruckle, Thomas, Chalon, Stephan, Phillips, Margaret A., Elliott, Suzanne, Sekuloski, Silvana, Griffin, Paul, Ng, Caroline L., Fidock, David A., Marquart, Louise, Williams, Noelle S., Gobeau, Nathalie, Bebrevska, Lidiya, Rosario, Maria, Marsh, Kennan and Mohrle, Jorg J. (2017). Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study. The Lancet Infectious Diseases, 17 (6), 626-635. doi: 10.1016/S1473-3099(17)30171-8

Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study

2017

Journal Article

First Australian case of disseminated Mycobacterium chimaera infection post-cardiothoracic surgery

Bursle, Evan, Playford, E. Geoffrey, Coulter, Chris and Griffin, Paul (2017). First Australian case of disseminated Mycobacterium chimaera infection post-cardiothoracic surgery. Infection, Disease and Health, 22 (1), 1-5. doi: 10.1016/j.idh.2017.01.003

First Australian case of disseminated Mycobacterium chimaera infection post-cardiothoracic surgery

2017

Journal Article

MALDI-TOF MS meets WGS in a VRE outbreak investigation

Schlebusch, S., Price, G. R., Gallagher, R. L., Horton-Szar, V., Elbourne, L. D. H., Griffin, P., Venter, D. J., Jensen, S. O. and van Hal, S. J. (2017). MALDI-TOF MS meets WGS in a VRE outbreak investigation. European Journal of Clinical Microbiology and Infectious Diseases, 36 (3), 1-5. doi: 10.1007/s10096-016-2824-4

MALDI-TOF MS meets WGS in a VRE outbreak investigation

2016

Journal Article

Plasmodium vivax controlled human malaria infection - progress and prospects

Payne, Ruth O., Griffin, Paul M., McCarthy, James S. and Draper, Simon J. (2016). Plasmodium vivax controlled human malaria infection - progress and prospects. Trends in Parasitology, 33 (2), 141-150. doi: 10.1016/j.pt.2016.11.001

Plasmodium vivax controlled human malaria infection - progress and prospects

2016

Journal Article

Safety and reproducibility of a clinical trial system using induced blood stage Plasmodium vivax infection and its potential as a model to evaluate malaria transmission

Griffin, Paul, Pasay, Cielo, Elliott, Suzanne, Sekuloski, Silvana, Sikulu, Maggy, Hugo, Leon, Khoury, David, Cromer, Deborah, Davenport, Miles, Sattabongkot, Jetsumon, Ivinson, Karen, Ockenhouse, Christian and McCarthy, James (2016). Safety and reproducibility of a clinical trial system using induced blood stage Plasmodium vivax infection and its potential as a model to evaluate malaria transmission. PLoS Neglected Tropical Diseases, 10 (12) e0005139, e0005139. doi: 10.1371/journal.pntd.0005139

Safety and reproducibility of a clinical trial system using induced blood stage Plasmodium vivax infection and its potential as a model to evaluate malaria transmission

2016

Journal Article

A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study

McCarthy, James S., Ruckle, Thomas, Djeriou, Elhadj, Cantalloube, Cathy, Ter-Minassian, Daniel, Baker, Mark, O'Rourke, Peter, Griffin, Paul, Marquart, Louise, van Huijsduijnen, Rob Hooft and Mohrle, Jorg J. (2016). A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study. Malaria Journal, 15 (469) 469, 469. doi: 10.1186/s12936-016-1511-3

A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study

2016

Journal Article

Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers

McCarthy, James S., Baker, Mark, O'Rourke, Peter, Marquart, Louise, Griffin, Paul, van huijsduijnen, Rob Hooft and Mohrle, Jorg J. (2016). Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers. Journal of Antimicrobial Chemotherapy, 71 (9), 2620-2627. doi: 10.1093/jac/dkw174

Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers

2016

Journal Article

Infectivity of Plasmodium falciparum in malaria-naive individuals is related to knob expression and cytoadherence of the parasite

Stanisic, Danielle I., Gerrard, John, Fink, James, Griffin, Paul M., Liu, Xue Q., Sundac, Lana, Sekuloski, Silvana, Rodriguez, Ingrid B., Pingnet, Jolien, Yang, Yuedong, Zhou, Yaoqi, Trenholme, Katharine R., Wang, Claire Y. T., Hackett, Hazel, Chan, Jo-Anne A., Langer, Christine, Hanssen, Eric, Hoffman, Stephen L., Beeson, James G., McCarthy, James S. and Good, Michael F. (2016). Infectivity of Plasmodium falciparum in malaria-naive individuals is related to knob expression and cytoadherence of the parasite. Infection and Immunity, 84 (9), 2689-2696. doi: 10.1128/IAI.00414-16

Infectivity of Plasmodium falciparum in malaria-naive individuals is related to knob expression and cytoadherence of the parasite

2016

Journal Article

An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1

Dutton, Julie L., Woo, Wai-Ping, Chandra, Janin, Xu, Yan, Li, Bo, Finlayson, Neil, Griffin, Paul and Frazer, Ian H. (2016). An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1. Human Vaccines and Immunotherapeutics, 12 (12), 3079-3088. doi: 10.1080/21645515.2016.1221872

An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1

2016

Journal Article

Piperaquine monotherapy of drug-susceptible Plasmodium falciparum infection results in rapid clearance of Parasitemia but is followed by the appearance of Gametocytemia

Pasay, Cielo J., Rockett, Rebecca, Sekuloski, Silvana, Griffin, Paul, Marquart, Louise, Peatey, Christopher, Wang, Claire Y. T., O'Rourke, Peter, Elliott, Suzanne, Baker, Mark, Möhrle, Jörg J. and McCarthy, James S. (2016). Piperaquine monotherapy of drug-susceptible Plasmodium falciparum infection results in rapid clearance of Parasitemia but is followed by the appearance of Gametocytemia. Journal of Infectious Diseases, 214 (1), 105-113. doi: 10.1093/infdis/jiw128

Piperaquine monotherapy of drug-susceptible Plasmodium falciparum infection results in rapid clearance of Parasitemia but is followed by the appearance of Gametocytemia

2016

Journal Article

Linking murine and human Plasmodium falciparum challenge models in a translational path for antimalarial drug development

McCarthy, James S., Marquart, Louise, Sekuloski, Silvana, Trenholme, Katherine, Elliott, Suzanne, Griffin, Paul, Rockett, Rebecca, O'Rourke, Peter, Sloots, Theo, Angulo-Barturen, Inigo, Ferrer, Santiago, Jimenez-Diaz, Maria Belen, Martinez, Maria-Santos, van Huijsduijnen, Rob Hoof, Duparc, Stephan, Leroy, Didier, Wells, Timothy N. C., Baker, Mark and Mohrle, Jorg J. (2016). Linking murine and human Plasmodium falciparum challenge models in a translational path for antimalarial drug development. Antimicrobial Agents and Chemotherapy, 60 (6), 3669-3675. doi: 10.1128/AAC.02883-15

Linking murine and human Plasmodium falciparum challenge models in a translational path for antimalarial drug development

2015

Journal Article

Acute vancomycin-resistant enterococcal bacteraemia outbreak analysis in haematology patients: a case-control study

Gassiep, Ian, Armstrong, Mark, Van Havre, Zoe, Schlebusch, Sanmarie, McCormack, Joseph and Griffin, Paul (2015). Acute vancomycin-resistant enterococcal bacteraemia outbreak analysis in haematology patients: a case-control study. Healthcare Infection, 20 (4), 115-123. doi: 10.1071/HI15013

Acute vancomycin-resistant enterococcal bacteraemia outbreak analysis in haematology patients: a case-control study

2015

Journal Article

Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609(Cipargamin) and Piperaquine

Stein, Daniel S, Jain, Jay Prakash, Kangas, Michael, Lefèvre, Gilbert, Machineni, Surendra, Griffin, Paul and Lickliterf, Jason (2015). Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609(Cipargamin) and Piperaquine. Antimicrobial Agents and Chemotherapy, 59 (6), 3493-3500. doi: 10.1128/AAC.00340-15

Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609(Cipargamin) and Piperaquine

2014

Journal Article

Delusions of disseminated fungosis

Gassiep, Ian and Griffin, Paul Matthew (2014). Delusions of disseminated fungosis. Case Reports in Infectious Diseases, 2014 (458028), 1-3. doi: 10.1155/2014/458028

Delusions of disseminated fungosis

2014

Journal Article

Vancomycin-induced linear IgA with mucosal and ocular involvement: a case report

Dang, Lily V., Byrom, Lisa, Muir, Jim and Griffin, Paul M. (2014). Vancomycin-induced linear IgA with mucosal and ocular involvement: a case report. Infectious Diseases in Clinical Practice, 22 (5), e119-e121. doi: 10.1097/IPC.0000000000000182

Vancomycin-induced linear IgA with mucosal and ocular involvement: a case report