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2024

Conference Publication

Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells

Dang, Thi Viet Trinh, Gillinder, Kevin R., Nguyen, Quan, Mulay, Onkar, Vo, Tuan, Mehdi, Ahmed M., Zhou, Chenhao, Brooks, Andrew J., Asplett, Kiran, Leggatt, Graham R., Hume, David A., Frazer, Ian H. and Chandra, Janin (2024). Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells. AACR Special Conference in Cancer Research: Tumor Immunology and Immunotherapy, Boston, MA, United States, 18-21 October 2024. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.tumimm24-a001

Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells

2023

Conference Publication

Contributions of maternal classical HLA alleles and KIR genes to the risk of miscarriages and stillbirths

Nunes, Caroline Brito, Decina, Caitlin, Hwang, Liang-Dar, Wang, Geng, Leggatt, Graham, Moen, Gunn-Helen and Evans, David (2023). Contributions of maternal classical HLA alleles and KIR genes to the risk of miscarriages and stillbirths. International Statistical Genetics Workshop, Boulder, CO United States, 5 - 11 March 2023.

Contributions of maternal classical HLA alleles and KIR genes to the risk of miscarriages and stillbirths

2023

Conference Publication

Contributions of Maternal Classical HLA Alleles and Spousal HLA Incompatibility to the Risk of Miscarriages and Stillbirths

Nunes, Caroline Brito, Hwang, Liang-Dar, Wang, Geng, Yengo, Loic, Leggatt, Graham, Moen, Gunn-Helen and Evans, David M. (2023). Contributions of Maternal Classical HLA Alleles and Spousal HLA Incompatibility to the Risk of Miscarriages and Stillbirths. 70th Annual Meeting of the Society for Reproductive Investigation (SRI), Brisbane Australia, Mar 21-25, 2023. HEIDELBERG: SPRINGER HEIDELBERG.

Contributions of Maternal Classical HLA Alleles and Spousal HLA Incompatibility to the Risk of Miscarriages and Stillbirths

2022

Conference Publication

Contributions of maternal classical HLA alleles to the risk of miscarriages and stillbirths

Brito Nunes, Caroline, Hwang, Liang-Dar, Wang, Geng, Leggatt, Graham, Moen, Gunn-Helen and Evans, David (2022). Contributions of maternal classical HLA alleles to the risk of miscarriages and stillbirths. Queensland Perinatal Consortium (QPaCt), Brisbane, QLD Australia, 15 December 2022.

Contributions of maternal classical HLA alleles to the risk of miscarriages and stillbirths

2022

Conference Publication

Targeting of immune regulatory proteins through locoregional delivery of mAbs augments CD8 T cell mediated anti-tumour responses in vivo

Wright, Q., Sinha, D., Gonzalez-Cruz, J., Frazer, I. and Leggatt, G. (2022). Targeting of immune regulatory proteins through locoregional delivery of mAbs augments CD8 T cell mediated anti-tumour responses in vivo. ESMO Immuno-Oncology Congress 2022, Geneva, Switzerland, 7-9 December 2022. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.iotech.2022.100289

Targeting of immune regulatory proteins through locoregional delivery of mAbs augments CD8 T cell mediated anti-tumour responses in vivo

2022

Conference Publication

Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity

Dang, T. V. T., Gillinder, K. G., Brooks, A. J., Asplett, K., Tolley, L. K., Hume, D. A., Leggatt, G. R., Frazer, I. H. and Chandra, J. (2022). Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity. 29th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy (ESCGT), Edinburgh, United Kingdom, 11-14 October 2022. New Rochelle, NY United States: Mary Ann Liebert.

Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity

2020

Conference Publication

Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin

Leggatt, Graham R., Salim, Nazhifah and Mattarollo, Stephen (2020). Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.165.27

Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin

2020

Conference Publication

Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis

Wright, Quentin, Minnie, Simone and Leggatt, Graham R. (2020). Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.241.23

Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis

2020

Conference Publication

Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin

Leggatt, Graham R., Salim, Nazhifah and Mattarollo, Stephen (2020). Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin. IMMUNOLOGY2020, Honolulu, HI, United States, 8-12 May, 2020. Rockville, MD, United States: American Association of Immunologists.

Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin

2020

Conference Publication

Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis

Wright, Quentin, Minnie, Simone and Leggatt, Graham R. (2020). Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis. IMMUNOLOGY2020, Honolulu, HI, United States, 8-12 May 2020. Rockville, MD, United States: American Association of Immunologists.

Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis

2016

Conference Publication

Modeling checkpoint blockade inhibitor resistant immunoregulation induced by squamous epithelial cancers

Mattarollo, Stephen, Leggatt, Graham, Wells, James, Lambert, Paul and Frazer, Ian H. (2016). Modeling checkpoint blockade inhibitor resistant immunoregulation induced by squamous epithelial cancers. International Cancer Immunotherapy Conference: Translating Science into Survival, New York, United States, September 16-19, 2015. Philadelphia, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.CRICIMTEATIAACR15-A064

Modeling checkpoint blockade inhibitor resistant immunoregulation induced by squamous epithelial cancers

2016

Conference Publication

Immunotherapy for persisting viral infection and associated cancer

Frazer, I, Mattarollo, S., Leggatt, G., Wells, J., Tuong, K., Kuo, P., Jazayeri, S., Lambert, P. and Chandra, J. (2016). Immunotherapy for persisting viral infection and associated cancer. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Immunotherapy for persisting viral infection and associated cancer

2016

Conference Publication

Inhibition of Aurora Kinases is curative for HPV-driven tumours

McMillan, N., Fallaha, S., Martin, D., Leggatt, G. and Gabrielli, B. (2016). Inhibition of Aurora Kinases is curative for HPV-driven tumours. 16th Biennial Meeting of the International Gynecologic Cancer Society, Lisbon, Portugal, 28-31 October 2016. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1097/01.IGC.0000503327.50238.5c

Inhibition of Aurora Kinases is curative for HPV-driven tumours

2016

Conference Publication

The implications of vaccination-induced IFN-gamma signalling on the control of B-cell lymphoma and the acquisition of immune resistance

Rearden, R., Sah, A., Doff, B., Kobayashi, T., McKee, S., Leggatt, G. and Mattarollo, S. (2016). The implications of vaccination-induced IFN-gamma signalling on the control of B-cell lymphoma and the acquisition of immune resistance. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

The implications of vaccination-induced IFN-gamma signalling on the control of B-cell lymphoma and the acquisition of immune resistance

2016

Conference Publication

Tissue resident CD103+CD69+ T cells develop rapidly and do not require cognate antigen within the epidermis of a mouse model of precancerous skin

Leggatt, G., Veitch, M., Sheehan, B., McKee, S., Linedale, R., Jazayeri, S. D. and Mattarollo, S. (2016). Tissue resident CD103+CD69+ T cells develop rapidly and do not require cognate antigen within the epidermis of a mouse model of precancerous skin. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Tissue resident CD103+CD69+ T cells develop rapidly and do not require cognate antigen within the epidermis of a mouse model of precancerous skin

2016

Conference Publication

Altered nutrient levels caused by B cell lymphoma leads to dysfunctional natural killer cells

Kobayashi, T., Tuong, K., Man, K., Mckee, S., Leggatt, G., Kallies, A. and Mattarollo, S. (2016). Altered nutrient levels caused by B cell lymphoma leads to dysfunctional natural killer cells. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Altered nutrient levels caused by B cell lymphoma leads to dysfunctional natural killer cells

2015

Conference Publication

Abstract 945: synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer

Gabrielli, Brian G., Bokhari, Fawzi, Ranall, Max, Oo, Zay Yar, Stevenson, Alex, Wang, Weili, McKee, Sara, Leggatt, Graham, Leo, Paul, Gonda, Thomas J. and McMillan, Nigel A. J. (2015). Abstract 945: synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer. 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA United States, 18-22 April 2015. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2015-945

Abstract 945: synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer

2014

Conference Publication

Synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer

Gabrielli, B., Bokhari, F., Ranall, M., Stevenson, A., Murell, M., Kelly, M., McKee, S., Leggatt, G., Gonda, T. and McMillan, N. (2014). Synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer. 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Barcelona Spain, 18-21 November 2014. Abingdon, Oxford, United Kingdom: Elsevier. doi: 10.1016/S0959-8049(14)70420-4

Synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer

2013

Conference Publication

Systemic lymphopenia results in loss of suppressive lymphocytes from precancerous skin

Leggatt, Graham, Mattarollo, Stephen, Yong, Michelle, Nissen, Michael and Frazer, Ian (2013). Systemic lymphopenia results in loss of suppressive lymphocytes from precancerous skin. 100th Annual Meeting of the American Association of Immunologists, Honolulu, Hawaii, 03-07 May 2013. Bethesda, MD United States: American Association of Immunologists.

Systemic lymphopenia results in loss of suppressive lymphocytes from precancerous skin

2009

Conference Publication

RNA interference for the treatment of cervical cancers: Solving the delivery and efficacy issues

Gu, W. Y., Leggatt, G., Payne, E., Wilson, D., Choyce, A. and McMillan, N. A. J. (2009). RNA interference for the treatment of cervical cancers: Solving the delivery and efficacy issues. 6th Meeting of the Australasian Gene Therapy Society, Sydney, Australia, 29 April - 01 May 2009. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/jgm.1375

RNA interference for the treatment of cervical cancers: Solving the delivery and efficacy issues