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2008 Journal Article Potent cationic inhibitors of West Nile Virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activityStoermer, Martin J., Chappell, Keith J., Liebscher, Susann, Jensen, Christina M., Gan, Chun H., Gupta, Praveer K., Xu, Wei-Jun, Young, Paul R. and Fairlie, David P. (2008). Potent cationic inhibitors of West Nile Virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity. Journal of Medicinal Chemistry, 51 (18), 5714-5721. doi: 10.1021/jm800503y |
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2008 Journal Article ChemInform Abstract: Synthesis and Cannabinoid Activity of 1-Substituted-indole-3-oxadiazole Derivatives: Novel Agonists for the CB1ReceptorMoloney, Gerard P., Angus, James A., Robertson, Alan D., Stoermer, Martin J., Robinson, Michael, Wright, Christine E., McRae, Ken and Christopoulos, Arthur (2008). ChemInform Abstract: Synthesis and Cannabinoid Activity of 1-Substituted-indole-3-oxadiazole Derivatives: Novel Agonists for the CB1Receptor. ChemInform, 39 (31) doi: 10.1002/chin.200831222 |
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2008 Journal Article Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activityChappell, Keith J., Stoermer, Martin J., Fairlie, David P. and Young, Paul R. (2008). Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity. Journal of General Virology, 89 (4), 1010-1014. doi: 10.1099/vir.0.83447-0 |
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2008 Journal Article Synthesis and cannabinoid activity of 1-substituted-Indole-3-oxadiazole derivatives: Novel agonists for the CB1 ReceptorMoloney, Gerard P., Angus, James A., Robertson, Alan D., Stoermer, Martin J., Robinson, Michael, Lay, Lucy, Wright, Christine E., McRae, Ken and Christopoulos, Arthur (2008). Synthesis and cannabinoid activity of 1-substituted-Indole-3-oxadiazole derivatives: Novel agonists for the CB1 Receptor. European Journal of Medicinal Chemistry, 43 (3), 513-539. doi: 10.1016/j.ejmech.2007.04.007 |
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2008 Journal Article Synthesis and cannabinoid activity of a variety of 2,3-substituted 1-Benzo[b]thiophen derivatives and 2,3-substituted benzofuran: Novel agonists for the CB1 receptorMoloney, Gerard P., Angus, James A., Robertson, Alan D., Stoermer, Martin J., Robinson, Michael, Lay, Lucy, Wright, Christine E., McRae, Ken and Christopoulos, Arthur (2008). Synthesis and cannabinoid activity of a variety of 2,3-substituted 1-Benzo[b]thiophen derivatives and 2,3-substituted benzofuran: Novel agonists for the CB1 receptor. Australian Journal of Chemistry, 61 (7), 484-499. doi: 10.1071/CH07412 |
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2007 Journal Article Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3Chappell, K. J., Stoermer, M. J., Fairlie, D. P. and Young, P. R. (2007). Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3. Protein Expression and Purification, 53 (1), 87-96. doi: 10.1016/j.pep.2006.10.022 |
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2006 Journal Article Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malariaAndrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin and McCarthy, James S. (2006). Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrobial Agents And Chemotherapy, 50 (2), 639-648. doi: 10.1128/AAC.50.2.639-648.2006 |
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2006 Journal Article Current Status of Virtual Screening as Analysed by Target ClassesStoermer, M J (2006). Current Status of Virtual Screening as Analysed by Target Classes. Medicinal Chemistry, 2 (1), 89-112. doi: 10.2174/157340606775197750 |
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2006 Journal Article Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studiesChappell, K. J., Stoermer, M. J., Fairlie, D. P. and Young, P. R. (2006). Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies. Journal of Biological Chemistry, 281 (50), 38448-38458. doi: 10.1074/jbc.M607641200 |
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2005 Journal Article Site-directed mutagenesis and kinetic studies of the West Nile virus NS3 protease identify key enzyme-substrate interactionsChappell, Keith J., Nall, Tessa A., Stoermer, Martin J., Fang, Ning-Xia, Tyndall, Joel D. A., Fairlie, David P. and Young, Paul R. (2005). Site-directed mutagenesis and kinetic studies of the West Nile virus NS3 protease identify key enzyme-substrate interactions. Journal of Biological Chemistry, 280 (4), 2896-2903. doi: 10.1074/jbc.M409931200 |
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2005 Journal Article Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazolesSingh, Y, Stoermer, MJ, Lucke, AJ, Guthrie, T and Fairlie, DP (2005). Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles. Journal of The American Chemical Society, 127 (18), 6563-6572. doi: 10.1021/ja0455300 |
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2004 Journal Article Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 proteaseNall, T. A., Chappell, K. J., Stoermer, M. J., Fang, N. X., Tyndall, J. D. A., Young, P. R. and Fairlie, D. P. (2004). Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease. Journal of Biological Chemistry, 279 (47), 48535-48542. doi: 10.1074/jbc.M406810200 |
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2004 Journal Article Potent cyclic antagonists of the complement C5a receptor on human polymorphonulcear leukocytes. Relationships between structures and activityMarch, Darren R., Proctor, Lavinia M., Stoermer, Martin J., Sbaglia, Robert, Abbenante, Giovanni, Reid, Robert C., Woodruff, Trent M., Wadi, Khemar, Paczkowski, Natalii, Tyndall, Joel D. A., Taylor, Stephen M. and Fairlie, David P. (2004). Potent cyclic antagonists of the complement C5a receptor on human polymorphonulcear leukocytes. Relationships between structures and activity. Molecular Pharmacology, 65 (4), 868-879. doi: 10.1124/mol.65.4.868 |
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2003 Journal Article Cycloadditions of isobenzofuran to a constrained template bearing neighboring dienophilesStoermer, M. J., Butler, D. N., Warrener, R. N., Weerasuria, K. D. V. and Fairlie, D. P. (2003). Cycloadditions of isobenzofuran to a constrained template bearing neighboring dienophiles. Chemistry-a European Journal, 9 (9), 2068-2071. doi: 10.1002/chem.200204619 |
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2002 Journal Article Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazolesSingh, Y, Stoermer, MJ, Lucke, AJ, Glenn, MP and Fairlie, DP (2002). Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles. Organic Letters, 4 (20), 3367-3370. doi: 10.1021/ol026463m |
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2001 Journal Article Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitorsLeung, D., Schroder, K., White, H., Fang, N. X., Stoermer, M. J., Abbenante, G., Martin, J. L., Young, P. R. and Fairlie, D. P. (2001). Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors. Journal of Biological Chemistry, 276 (49), 45762-45771. doi: 10.1074/jbc.M107360200 |
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1998 Journal Article 2-(Het)aryl-Substituted 7-Azabicyclo[2.2.1]heptane SystemsOtten, Albert, Namyslo, Jan Christoph, Stoermer, Martin and Kaufmann, Dieter E. (1998). 2-(Het)aryl-Substituted 7-Azabicyclo[2.2.1]heptane Systems. European Journal of Organic Chemistry, 1998 (9), 1997-2001. doi: 10.1002/(sici)1099-0690(199809)1998:93.0.co;2-a |
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1998 Journal Article Chemistry in the ambient field of the alkaloid epibatidine, 1 - 2-(het)aryl-substituted 7-azabicyclo[2.2.1]heptane systemsOtten, A, Namyslo, JC, Stoermer, M and Kaufmann, DE (1998). Chemistry in the ambient field of the alkaloid epibatidine, 1 - 2-(het)aryl-substituted 7-azabicyclo[2.2.1]heptane systems. European Journal of Organic Chemistry, 1998 (9), 1997-2001. |
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1998 Journal Article Ethyl (E)-2-Methyl-5-phenyl-2-pentenoateStoermer, Martin and Pinhey, John (1998). Ethyl (E)-2-Methyl-5-phenyl-2-pentenoate. Molecules, 3 (3), M62. doi: 10.3390/m62 |
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1998 Journal Article Ethyl (Z)-2-Methyl-5-phenyl-2-pentenoateStoermer, Martin and Pinhey, John (1998). Ethyl (Z)-2-Methyl-5-phenyl-2-pentenoate. Molecules, 3 (8), M63. doi: 10.3390/m63 |
