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2020

Journal Article

Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury

Wang, Haolu, Burke, Leslie J., Patel, Jatin, Tse, Brian W.C., Bridle, Kim R., Cogger, Victoria C., Li, Xinxing, Liu, Xin, Yang, Haotian, Crawford, Darrell H. G., Roberts, Michael S., Gao, Wenchao and Liang, Xiaowen (2020). Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury. Theranostics, 10 (15), 6715-6727. doi: 10.7150/thno.44900

Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury

2019

Journal Article

Immune checkpoint blockade therapies for HCC: current status and future implications

Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G. and Jayachandran, Aparna (2019). Immune checkpoint blockade therapies for HCC: current status and future implications. Hepatoma Research, 2019 (5) 32. doi: 10.20517/2394-5079.2019.24

Immune checkpoint blockade therapies for HCC: current status and future implications

2019

Journal Article

Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury

Núñez, Kelley G., Frank, Anderson, Gonzalez-Rosario, Janet, Galliano, Gretchen, Bridle, Kim, Crawford, Darrell, Seal, John, Abbruscato, Frank, Vashistha, Himanshu, Thevenot, Paul T. and Cohen, Ari J. (2019). Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury. PLoS One, 14 (4) e0216242, e0216242. doi: 10.1371/journal.pone.0216242

Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury

2019

Conference Publication

Attenuation of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like pseudokinase (MLKL) blocks the TRIF-RIPK3-MLKL-driven necroptotic cell death in steatotic hepatocytes undergoing ischemic injury

Baidya, R., Jaskowski, L., Gautheron, J., Jayachandran, A., Wang, H., Thevenot, P., Cohen, A., Crawford, D. and Bridle, K. (2019). Attenuation of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like pseudokinase (MLKL) blocks the TRIF-RIPK3-MLKL-driven necroptotic cell death in steatotic hepatocytes undergoing ischemic injury. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide Convention Centre, 8-10 September 2019. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/jgh.14798

Attenuation of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like pseudokinase (MLKL) blocks the TRIF-RIPK3-MLKL-driven necroptotic cell death in steatotic hepatocytes undergoing ischemic injury

2019

Conference Publication

Tumor necrosis factor-alpha promotes epithelial-to-mesenchymal transition and expression of immune checkpoint molecules in hepatocellular carcinoma

Shrestha, R., Bridle, K., Cao, L., Crawford, D. and Jayachandran, A. (2019). Tumor necrosis factor-alpha promotes epithelial-to-mesenchymal transition and expression of immune checkpoint molecules in hepatocellular carcinoma. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide Convention Centre, 8-10 September 2019. Richmond, VIC, Australia: Wiley-Blackwell.

Tumor necrosis factor-alpha promotes epithelial-to-mesenchymal transition and expression of immune checkpoint molecules in hepatocellular carcinoma

2019

Journal Article

Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma

Huang, I-Tao, Dhungel, Bijay, Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G., Jayachandran, Aparna and Steel, Jason C (2019). Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma. Expert Opinion on Investigational Drugs, 28 (1), 7-18. doi: 10.1080/13543784.2019.1551359

Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma

2019

Conference Publication

Enrichment of multiple immune checkpoints in cholangiocarcinoma cancer stem cells

Cao, L., Shrestha, R., Bridle, K., Crawford, D. and Jayachandran, A. (2019). Enrichment of multiple immune checkpoints in cholangiocarcinoma cancer stem cells. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide Convention Centre, 8-10 September 2019. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/jgh.14797

Enrichment of multiple immune checkpoints in cholangiocarcinoma cancer stem cells

2018

Journal Article

Exosome-based liquid biopsy in the management of hepatocellular carcinoma

Jayachandran, Aparna, Manda, Sasidhar Venkata, Shrestha, Ritu, Bridle, Kim R., Prithviraj, Prashanth and Crawford, Darrell H. G. (2018). Exosome-based liquid biopsy in the management of hepatocellular carcinoma. Hepatoma Research, 4 (8) 44, 44. doi: 10.20517/2394-5079.2018.59

Exosome-based liquid biopsy in the management of hepatocellular carcinoma

2018

Journal Article

Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma

Shrestha, Ritu, Prithviraj, Prashanth, Anaka, Matthew, Bridle, Kim R., Crawford, Darrell H. G., Dhungel, Bijay, Steel, Jason C. and Jayachandran, Aparna (2018). Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma. Frontiers in Oncology, 8 (JUL) 269, 269. doi: 10.3389/fonc.2018.00269

Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma

2018

Journal Article

Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease

Britton, Laurence, Bridle, Kim, Reiling, Janske, Santrampurwala, Nishreen, Wockner, Leesa, Ching, Helena, Stuart, Katherine, Subramaniam, V Nathan, Jeffrey, Gary, St Pierre, Tim, House, Michael, Gummer, Joel, Trengove, Robert, Olynyk, John, Crawford, Darrell and Adams, Leon (2018). Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease. Hepatology Communications, 2 (6), 644-653. doi: 10.1002/hep4.1190

Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease

2018

Journal Article

Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet

Britton, Laurence, Jaskowski, Lesley-Anne, Bridle, Kim, Secondes, Eriza, Wallace, Daniel, Santrampurwala, Nishreen, Reiling, Janske, Miller, Gregory, Mangiafico, Salvatore, Andrikopoulos, Sofianos, Subramaniam, V. Nathan and Crawford, Darrell (2018). Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet. CMGH, 5 (3), 319-331. doi: 10.1016/j.jcmgh.2018.01.005

Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet

2018

Conference Publication

Comparable Levels of Inflammatory Mediators in Portal Venous Blood Collected from Organ Donors Donating after Circulatory Death and those Donating after Brain Death

Reiling, Janske, Hohenhaus, Daniel M., Sweet, Matt J., Raj, Ashok S., Campbell, Catherine M., Bridle, Kim R., Santrampurwala, Nishreen, Britton, Laurence J., Crawford, Darrell H. G., Dejong, Cornelis H. C. and Fawcett, Jonathan (2018). Comparable Levels of Inflammatory Mediators in Portal Venous Blood Collected from Organ Donors Donating after Circulatory Death and those Donating after Brain Death. 14th World Congress of the International-Pancreas-and-Islet-Transplant-Association (IPITA), Monterey Ca, 24-27 September 2013. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.tp.0000543959.06247.92

Comparable Levels of Inflammatory Mediators in Portal Venous Blood Collected from Organ Donors Donating after Circulatory Death and those Donating after Brain Death

2018

Conference Publication

Necroptosis Contributes to Cell Death of Steatotic Hepatocytes Following Ischaemic Injury

Baidya, Raji, Jaskowski, Lesley, Jayachandran, Aparna, Thevenot, Paul, Cohen, Ari J., Crawford, Darrell H.G. and Bridle, Kim (2018). Necroptosis Contributes to Cell Death of Steatotic Hepatocytes Following Ischaemic Injury. Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) / Liver Meeting, San Francisco, California, 9-13 November 2018 . Hoboken, NJ, United States: John Wiley & Sons.

Necroptosis Contributes to Cell Death of Steatotic Hepatocytes Following Ischaemic Injury

2018

Journal Article

Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes

Britton, L. J., Bridle, Kim, Jaskowski, Lesley-Anne, He, Jingjing, Ng, Choaping, Ruelcke, Jayde E., Mohamed, Ahmed, Reiling, Janske, Santrampurwala, Nishreen, Hill, Michelle M., Whitehead, Jonathan P., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2018). Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes. Cellular and Molecular Gastroenterology and Hepatology, 6 (2), 214-217. doi: 10.1016/j.jcmgh.2018.04.005

Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes

2018

Conference Publication

Prognostic Impact of Immune Checkpoint Inhibitor Expression and Its Association with Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

Shrestha, Ritu, Prithiviraj, Prashanth, Bridle, Kim, Anake, Matthew, Crawford, Darrell H. G. and Jayachandran, Aparna (2018). Prognostic Impact of Immune Checkpoint Inhibitor Expression and Its Association with Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma. Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) / Liver Meeting, San Francisco, CA United States, 9-13 November 2018. Hoboken, NJ United States: Wiley.

Prognostic Impact of Immune Checkpoint Inhibitor Expression and Its Association with Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

2018

Conference Publication

Inflammatory Pathways in Adipocytes Are Activated By Ferritin and Iron

Jaskowski, Lesley, Bridle, Kim, Britton, Laurence J., Jayachandran, Apama, Ramm, Grant A. and Crawford, Darrell H. G. (2018). Inflammatory Pathways in Adipocytes Are Activated By Ferritin and Iron. Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco, CA, United States, 9-13 November 2018. Hoboken, NJ United States: Wiley.

Inflammatory Pathways in Adipocytes Are Activated By Ferritin and Iron

2017

Journal Article

The Implications of the Shift Toward Donation After Circulatory Death in Australia

Reiling, Janske, Forrest, Elizabeth, Bridle, Kim R., Britton, Laurence J., Santrampurwala, Nishreen, Crawford, Darrell H. G., Dejong, Cornelis H. C. and Fawcett, Jonathan (2017). The Implications of the Shift Toward Donation After Circulatory Death in Australia. Transplantation Direct, 3 (12) e226, 1-7. doi: 10.1097/TXD.0000000000000743

The Implications of the Shift Toward Donation After Circulatory Death in Australia

2017

Conference Publication

Do macrophages play a role in the development of endotoxin-induced biliary injury in rats?

Reiling, J., Bridle, K. B., Schaap, F. G., Jaskowski, L., Santrampurwala, N., Britton, L. J., Campbell, C. M., Damink, S. W. M. Olde, Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2017). Do macrophages play a role in the development of endotoxin-induced biliary injury in rats?. HOBOKEN: WILEY.

Do macrophages play a role in the development of endotoxin-induced biliary injury in rats?

2017

Journal Article

The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model

Reiling, J., Bridle, K. R., Schaap, F. G., Jaskowski, L., Santrampurwala, N., Britton, L. J., Campbell, C. M., Jansen, P. L. M., Damink, S. W. M. O., Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2017). The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model. Biochimica et Biophysica Acta, 1864 (4 Pt B), 1284-1292. doi: 10.1016/j.bbadis.2017.06.028

The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model

2017

Journal Article

Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice

Heritage, Mandy, Jaskowski, Lesley, Bridle, Kim, Campbell, Catherine, Briskey, David, Britton, Laurence, Fletcher, Linda, Vitetta, Luis, Subramaniam, V. Nathan and Crawford, Darrell (2017). Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice. World Journal of Gastrointestinal Pathophysiology, 8 (2), 67-76. doi: 10.4291/wjgp.v8.i2.67

Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice