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2021

Journal Article

An ovine model of haemorrhagic shock and resuscitation, to assess recovery of tissue oxygen delivery and oxygen debt, and inform patient blood management

Dyer, Wayne B., Tung, John-Paul, Li Bassi, Gianluigi, Wildi, Karin, Jung, Jae-Seung, Colombo, Sebastiano Maria, Rozencwajg, Sacha, Simonova, Gabriela, Chiaretti, Sara, Temple, Fergal T., Ainola, Carmen, Shuker, Tristan, Palmieri, Chiara, Shander, Aryeh, Suen, Jacky Y., Irving, David O. and Fraser, John F. (2021). An ovine model of haemorrhagic shock and resuscitation, to assess recovery of tissue oxygen delivery and oxygen debt, and inform patient blood management. Shock, 56 (6), 1080-1091. doi: 10.1097/SHK.0000000000001805

An ovine model of haemorrhagic shock and resuscitation, to assess recovery of tissue oxygen delivery and oxygen debt, and inform patient blood management

2021

Journal Article

Abstract 10482: Renin-Angiotensin-Aldosterone System Inhibition is Associated with Reduced In-Hospital Mortality in Critically Ill Covid-19 Patients with Pre-Existing Hypertension

Sato, Kei, White, Nicole, Fanning, Jonathon P, Obonyo, Nchafatso, Appadurai, Vinesh, Ciullo, Anna, May, Meryta, Worku, Elliott, Helms, Leticia, Ohshimo, Shinichiro, Yamashita, Michael, Suen, Jacky Y, Bassi, Gianluigi Li, Fraser, John F and ARORA, Rakesh C (2021). Abstract 10482: Renin-Angiotensin-Aldosterone System Inhibition is Associated with Reduced In-Hospital Mortality in Critically Ill Covid-19 Patients with Pre-Existing Hypertension. Circulation, 144 (Suppl_1). doi: 10.1161/circ.144.suppl_1.10482

Abstract 10482: Renin-Angiotensin-Aldosterone System Inhibition is Associated with Reduced In-Hospital Mortality in Critically Ill Covid-19 Patients with Pre-Existing Hypertension

2021

Journal Article

Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study

Li Bassi, Gianluigi, Suen, Jacky Y., White, Nicole, Dalton, Heidi J., Fanning, Jonathon, Corley, Amanda, Shrapnel, Sally, Hinton, Samuel, Forsyth, Simon, Parsons, Rex, Laffey, John G., Fan, Eddy, Bartlett, Robert, Brodie, Daniel, Burrell, Aidan, Chiumello, Davide, Elhazmi, Alyaa, Grasselli, Giacomo, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Marwali, Eva, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Panigada, Mauro, Pelosi, Paolo, Torres, Antoni, Ng, Pauline Yeung ... Obonyo, Nchafatso (2021). Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study. Critical Care Explorations, 3 (11) e0567, e0567. doi: 10.1097/cce.0000000000000567

Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study

2021

Journal Article

Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M, Kim, Hyung-Sook, Levkovich, Bianca J., Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Fraser, John F., Shekar, Kiran, Roberts, Jason A. and on behalf of ASAP ECMO Investigators (2021). Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Antimicrobial Agents and Chemotherapy, 65 (11) e01438-21, 1-11. doi: 10.1128/aac.01438-21

Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

2021

Journal Article

Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model

Walweel, K., Boon, A. C., See Hoe, L. E., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Colombo, S. M., Bartnikowski, N. J., Bouquet, M., Wells, M. A., Black, D. M., Pimenta, L. P., Stevenson, A. K., Bisht, K., Skeggs, K., Marshall, L., Prabhu, A., James, L. N., Platts, D. G., Macdonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2021). Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model. Biomedical Journal, 45 (5), 776-787. doi: 10.1016/j.bj.2021.10.007

Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model

2021

Journal Article

An innovative ovine model of severe cardiopulmonary failure supported by veno-arterial extracorporeal membrane oxygenation

Heinsar, Silver, Jung, Jae-Seung, Colombo, Sebastiano Maria, Rozencwajg, Sacha, Wildi, Karin, Sato, Kei, Ainola, Carmen, Wang, Xiaomeng, Abbate, Gabriella, Sato, Noriko, Dyer, Wayne Bruce, Livingstone, Samantha Annie, Pimenta, Leticia Pretti, Bartnikowski, Nicole, Bouquet, Mahe Jeannine Patricia, Passmore, Margaret, Vidal, Bruno, Palmieri, Chiara, Reid, Janice D., Haqqani, Haris M., McGuire, Daniel, Wilson, Emily Susan, Rätsep, Indrek, Lorusso, Roberto, Suen, Jacky Y., Li Bassi, Gianluigi and Fraser, John F. (2021). An innovative ovine model of severe cardiopulmonary failure supported by veno-arterial extracorporeal membrane oxygenation. Scientific Reports, 11 (1) 20458, 1-11. doi: 10.1038/s41598-021-00087-y

An innovative ovine model of severe cardiopulmonary failure supported by veno-arterial extracorporeal membrane oxygenation

2021

Journal Article

Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study

Millar, Jonathan E., Wildi, Karin, Bartnikowski, Nicole, Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Ki, Katrina K., See Hoe, Louise E., Obonyo, Nchafatso G., Neyton, Lucile, Pedersen, Sanne, Rozencwajg, Sacha, Baillie, J. Kenneth, Li Bassi, Gianluigi, Suen, Jacky Y., McAuley, Daniel F. and Fraser, John F. (2021). Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study. Physiological Reports, 9 (19) e15048, e15048. doi: 10.14814/phy2.15048

Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study

2021

Journal Article

Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury

Redd, Meredith A., Scheuer, Sarah E., Saez, Natalie J., Yoshikawa, Yusuke, Chiu, Han Sheng, Gao, Ling, Hicks, Mark, Villanueva, Jeanette E., Joshi, Yashutosh, Chow, Chun Yuen, Cuellar-Partida, Gabriel, Peart, Jason N., See Hoe, Louise E., Chen, Xiaoli, Sun, Yuliangzi, Suen, Jacky Y., Hatch, Robert J., Rollo, Ben, Xiao, Di, Alzubaidi, Mubarak A.H., Maljevic, Snezana, Quaife-Ryan, Gregory A., Hudson, James E., Porrello, Enzo R., White, Melanie Y., Cordwell, Stuart J., Fraser, John F., Petrou, Steven, Reichelt, Melissa E. ... Palpant, Nathan J. (2021). Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury. Circulation, 144 (12), 947-960. doi: 10.1161/circulationaha.121.054360

Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury

2021

Journal Article

Design and rationale of a prospective international follow-up study on intensive care survivors of COVID-19: The long-term impact in intensive care survivors of coronavirus disease-19-AFTERCOR

Wildi, Karin, Li Bassi, Gianluigi, Barnett, Adrian, Panigada, Mauro, Colombo, Sebastiano M., Bandera, Alessandra, Muscatello, Antonio, McNicholas, Bairbre, Laffey, John G., Battaglini, Denise, Robba, Chiara, Torres, Antoni, Motos, Ana, Luna, Carlos M., Rainieri, Fernando, Hodgson, Carol, Burrell, Aidan J. C., Buscher, Hergen, Dalton, Heidi, Cho, Sung-Min, Choi, Huimahn Alex, Thomson, David, Suen, Jacky and Fraser, John F. (2021). Design and rationale of a prospective international follow-up study on intensive care survivors of COVID-19: The long-term impact in intensive care survivors of coronavirus disease-19-AFTERCOR. Frontiers in Medicine, 8 738086, 738086. doi: 10.3389/fmed.2021.738086

Design and rationale of a prospective international follow-up study on intensive care survivors of COVID-19: The long-term impact in intensive care survivors of coronavirus disease-19-AFTERCOR

2021

Journal Article

Cardiovascular disease in SARS‐CoV‐2 infection

Sato, Kei, Sinclair, Jane E., Sadeghirad, Habib, Fraser, John F., Short, Kirsty R. and Kulasinghe, Arutha (2021). Cardiovascular disease in SARS‐CoV‐2 infection. Clinical and Translational Immunology, 10 (9) e1343, e1343. doi: 10.1002/cti2.1343

Cardiovascular disease in SARS‐CoV‐2 infection

2021

Journal Article

Anti-thrombogenic surface coatings for extracorporeal membrane oxygenation: a narrative review

Zhang, Meili, Pauls, Jo P., Bartnikowski, Nicole, Haymet, Andrew B., Chan, Chris H. H., Suen, Jacky Y., Schneider, Bailey, Ki, Katrina K., Whittaker, Andrew K., Dargusch, Matthew S. and Fraser, John F. (2021). Anti-thrombogenic surface coatings for extracorporeal membrane oxygenation: a narrative review. ACS Biomaterials Science and Engineering, 7 (9), 4402-4419. doi: 10.1021/acsbiomaterials.1c00758

Anti-thrombogenic surface coatings for extracorporeal membrane oxygenation: a narrative review

2021

Journal Article

Coagulation dysfunction in acute respiratory distress syndrome and its potential impact in inflammatory subphenotypes

Livingstone, Samantha A., Wildi, Karin S., Dalton, Heidi J., Usman, Asad, Ki, Katrina K., Passmore, Margaret R., Li Bassi, Gianluigi, Suen, Jacky Y. and Fraser, John F. (2021). Coagulation dysfunction in acute respiratory distress syndrome and its potential impact in inflammatory subphenotypes. Frontiers in Medicine, 8 723217, 723217. doi: 10.3389/fmed.2021.723217

Coagulation dysfunction in acute respiratory distress syndrome and its potential impact in inflammatory subphenotypes

2021

Journal Article

Prophylactic postoperative high flow nasal oxygen versus conventional oxygen therapy in obese patients undergoing bariatric surgery (OXYBAR Study): a pilot randomised controlled trial

Fulton, Rachel, Millar, Jonathan E., Merza, Megan, Johnston, Helen, Corley, Amanda, Faulke, Daniel, Rapchuk, Ivan L., Tarpey, Joe, Fanning, Jonathon P., Lockie, Philip, Lockie, Shirley and Fraser, John F. (2021). Prophylactic postoperative high flow nasal oxygen versus conventional oxygen therapy in obese patients undergoing bariatric surgery (OXYBAR Study): a pilot randomised controlled trial. Obesity Surgery, 31 (11), 4799-4807. doi: 10.1007/s11695-021-05644-y

Prophylactic postoperative high flow nasal oxygen versus conventional oxygen therapy in obese patients undergoing bariatric surgery (OXYBAR Study): a pilot randomised controlled trial

2021

Journal Article

Neurological manifestations of coronavirus disease 2019: a comprehensive review and meta-analysis of the first 6 months of pandemic reporting

Huth, Samuel F., Cho, Sung-Min, Robba, Chiara, Highton, David, Battaglini, Denise, Bellapart, Judith, Suen, Jacky Y., Li Bassi, Gianluigi, Taccone, Fabio Silvio, Arora, Rakesh C., Whitman, Glenn, Fraser, John F. and Fanning, Jonathon P. (2021). Neurological manifestations of coronavirus disease 2019: a comprehensive review and meta-analysis of the first 6 months of pandemic reporting. Frontiers in Neurology, 12 664599, 664599. doi: 10.3389/fneur.2021.664599

Neurological manifestations of coronavirus disease 2019: a comprehensive review and meta-analysis of the first 6 months of pandemic reporting

2021

Journal Article

Surface coatings for rotary ventricular assist devices: a systematic review

Zhang, Meili, Tansley, Geoffrey D., Dargusch, Matthew S., Fraser, John F. and Pauls, Jo P. (2021). Surface coatings for rotary ventricular assist devices: a systematic review. ASAIO Journal, 68 (5), 623-632. doi: 10.1097/MAT.0000000000001534

Surface coatings for rotary ventricular assist devices: a systematic review

2021

Journal Article

Global infectious disease research collaborations in crises: building capacity and inclusivity through cooperation

Fanning, Jonathon P., Murthy, Srinivas, Obonyo, Nchafatso G., Baillie, J. Kenneth, Webb, Steve, Dalton, Heidi J. and Fraser, John F. (2021). Global infectious disease research collaborations in crises: building capacity and inclusivity through cooperation. Globalization and Health, 17 (1) 84, 1-6. doi: 10.1186/s12992-021-00731-2

Global infectious disease research collaborations in crises: building capacity and inclusivity through cooperation

2021

Journal Article

Ischemic and hemorrhagic stroke among critically ill patients with coronavirus disease 2019: an International Multicenter Coronavirus Disease 2019 Critical Care Consortium study

Cho, Sung-Min, Premraj, Lavienraj, Fanning, Jonathon, Huth, Samuel, Barnett, Adrian, Whitman, Glenn, Arora, Rakesh C., Battaglini, Denise, Porto, Diego Bastos, Choi, HuiMahn, Suen, Jacky, Bassi, Gianluigi Li, Fraser, John F., Robba, Chiara and Griffee, Matthew (2021). Ischemic and hemorrhagic stroke among critically ill patients with coronavirus disease 2019: an International Multicenter Coronavirus Disease 2019 Critical Care Consortium study. Critical Care Medicine, 49 (12), E1223-E1233. doi: 10.1097/CCM.0000000000005209

Ischemic and hemorrhagic stroke among critically ill patients with coronavirus disease 2019: an International Multicenter Coronavirus Disease 2019 Critical Care Consortium study

2021

Journal Article

Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death

Wells, Matthew A., See Hoe, Louise E., Molenaar, Peter, Pedersen, Sanne, Obonyo, Nchafatso G., McDonald, Charles I., Mo, Weilan, Bouquet, Mahè, Hyslop, Kieran, Passmore, Margaret R., Bartnikowski, Nicole, Suen, Jacky Y., Peart, Jason N., McGiffin, David C., Fraser, John F. and on behalf of the Dead Heart Project (2021). Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death. Pharmacological Research, 169 105631, 1-12. doi: 10.1016/j.phrs.2021.105631

Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death

2021

Journal Article

An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients

Li Bassi, Gianluigi, Suen, Jacky Y, Dalton, Heidi J, White, Nicole, Shrapnel, Sally, Fanning, Jonathon P, Liquet, Benoit, Hinton, Samuel, Vuorinen, Aapeli, Booth, Gareth, Millar, Jonathan E, Forsyth, Simon, Panigada, Mauro, Laffey, John, Brodie, Daniel, Fan, Eddy, Torres, Antoni, Chiumello, Davide, Corley, Amanda, Elhazmi, Alyaa, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Murthy, Srinivas, Nichol, Alistair, Ng, Pauline Yeung, Ogino, Mark, Pesenti, Antonio, Trieu, Huynh Trung ... Obonyo, Gikenyi N. (2021). An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients. Critical Care, 25 (1) 199, 1-22. doi: 10.1186/s13054-021-03518-4

An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients

2021

Journal Article

Ethical factors determining ECMO allocation during the COVID-19 pandemic

Dao, Bernadine, Savulescu, Julian, Suen, Jacky Y., Fraser, John F. and Wilkinson, Dominic J. C. (2021). Ethical factors determining ECMO allocation during the COVID-19 pandemic. BMC Medical Ethics, 22 (1) 70, 1-12. doi: 10.1186/s12910-021-00638-y

Ethical factors determining ECMO allocation during the COVID-19 pandemic