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2015 Journal Article The role of H4 flagella in Escherichia coli ST131 virulenceKakkanat, Asha, Totsika, Makrina, Schaale, Kolja, Duell, Benjamin L., Lo, Alvin W., Phan, Minh-Duy, Moriel, Danilo G., Beatson, Scott A., Sweet, Matthew J., Ulett, Glen C. and Schembri, Mark A. (2015). The role of H4 flagella in Escherichia coli ST131 virulence. Scientific Reports, 5 (16149) 16149, 1-14. doi: 10.1038/srep16149 |
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2015 Journal Article Inhibition of histone deacetylases permits lipopolysaccharide-mediated secretion of bioactive IL-1b via a caspase-1-independent mechanismStammler, Dominik, Eigenbrod, Tatjana, Menz, Sarah, Frick, Julia S., Sweet, Matthew J., Shakespear, Melanie R., Jantsch, Jonathan, Siegert, Isabel, Wolfle, Sabine, Langer, Julian D., Oehme, Ina, Schaefer, Liliana, Fischer, Andre, Knievel, Judith, Heeg, Klaus, Dalpke, Alexander H. and Bode, Konrad A. (2015). Inhibition of histone deacetylases permits lipopolysaccharide-mediated secretion of bioactive IL-1b via a caspase-1-independent mechanism. Journal of Immunology, 195 (11), 5421-5431. doi: 10.4049/jimmunol.1501195 |
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2015 Journal Article Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injuryIrvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury. Fibrogenesis and Tissue Repair, 8 (19) 19, 19. doi: 10.1186/s13069-015-0036-7 |
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2015 Journal Article Uropathogenic Escherichia coli engages CD14-dependent signaling to enable bladder macrophage-dependent control of acute urinary tract infectionCarey, Alison J., Sullivan, Matthew J., Duell, Benjamin L., Crossman, David K., Chattopadhyay, Debasish., Brooks, Andrew J., Tan, Chee K., Crowley, Michael., Sweet, Matthew J., Schembri, Mark A. and Ulett, Glen C. (2015). Uropathogenic Escherichia coli engages CD14-dependent signaling to enable bladder macrophage-dependent control of acute urinary tract infection. The Journal of infectious diseases, 213 (4), 659-668. doi: 10.1093/infdis/jiv424 |
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2015 Journal Article TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytesRamnath, Divya, Tunny, Kathryn, Hohenhaus, Daniel M., Pitts, Claire M., Bergot, Anne-Sophie, Hogarth, P. Mark, Hamilton, John A., Kapetanovic, Ronan, Sturm, Richard A., Scholz, Glen M. and Sweet, Matthew J. (2015). TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes. Immunology and Cell Biology, 93 (9), 771-779. doi: 10.1038/icb.2015.77 |
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2015 Journal Article HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombiAhrens, Ingo, Chen, Yung-Chih, Topcic, Danijal, Bode, Michael, Haenel, David, Hagemeyer, Christoph E., Seeba, Hannah, Duerschmied, Daniel, Bassler, Nicole, Jandeleit-Dahm, Karin A., Sweet, Matthew J., Agrotis, Alex, Bobik, Alex and Peter, Karlheinz (2015). HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi. Thrombosis and Haemostasis, 114 (5), 994-1003. doi: 10.1160/TH14-12-1073 |
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2015 Journal Article Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.Sester, David P., Sagulenko, Vitaliya, Thygesen, Sara J., Cridland, Jasmyn A., Loi, Yen Siew, Cridland, Simon O., Masters, Seth L., Genske, Ulrich, Hornung, Veit, Andoniou, Christopher E., Sweet, Matthew J., Degli-Esposti, Mariapia A., Schroder, Kate and Stacey, Katryn J. (2015). Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.. Journal of Immunology, 195 (3), 1233-1241. doi: 10.4049/jimmunol.1402859 |
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2015 Journal Article Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: a ticking time bomb in ageingKapetanovic, Ronan, Bokil, Nilesh J. and Sweet, Matthew J. (2015). Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: a ticking time bomb in ageing. Ageing Research Reviews, 24 (Pt A), 40-53. doi: 10.1016/j.arr.2015.02.005 |
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2015 Journal Article The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host–pathogen interactionsMavromatis, Charalampos (Harris), Bokil, Nilesh J., Totsika, Makrina, Kakkanat, Asha, Schaale, Kolja, Cannistraci, Carlo V., Ryu, Taewoo, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A., Sweet, Matthew J. and Ravasi, Timothy (2015). The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host–pathogen interactions. Cellular Microbiology, 17 (5), 730-746. doi: 10.1111/cmi.12397 |
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2014 Journal Article Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migrationIrvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014). Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 (47), 17851-17862. doi: 10.3748/wjg.v20.i47.17851 |
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2014 Journal Article Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiationKwa, Mei Qi, Huynh, Jennifer, Aw, Jiamin, Zhang, Lianyi, Nguyen, Thao, Reynolds, Eric C., Sweet, Matthew J., Hamilton, John A. and Scholz, Glen M. (2014). Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation. Journal of Biological Chemistry, 289 (45), 31077-31087. doi: 10.1074/jbc.M114.589382 |
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Featured 2014 Journal Article The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella ChallengeChen, Kaiwen W., Groß, Christina J., Vasquez Sotomayor, Flor, Stacey, Katryn J., Tschopp, Jurg, Sweet, Matthew J. and Schroder, Kate (2014). The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge. Cell Reports, 8 (2), 570-582. doi: 10.1016/j.celrep.2014.06.028 |
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2014 Journal Article Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cellsKwa, Mei Qi, Nguyen, Thao, Huynh, Jennifer, Ramnath, Divya, De Nardo, Dominic, Lam, Pei Yeng, Reynolds, Eric C., Hamilton, John A., Sweet, Matthew J. and Scholz, Glen M. (2014). Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cells. Journal of Biological Chemistry, 289 (28), 19758-19768. doi: 10.1074/jbc.M114.584540 |
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2014 Journal Article Towards selective lysophospholipid GPCR modulatorsArchbold, Julia K., Martin, Jennifer L. and Sweet, Matthew J. (2014). Towards selective lysophospholipid GPCR modulators. Trends in Pharmacological Sciences, 35 (5), 219-226. doi: 10.1016/j.tips.2014.03.004 |
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2014 Journal Article Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasisSchroder, Wayne A., Major, Lee D., Le, Thuy T., Gardner, Joy, Sweet, Matthew J., Janciauskiene, Sabina and Suhrbier, Andreas (2014). Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis. Cancer Medicine, 3 (3), 500-513. doi: 10.1002/cam4.229 |
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2014 Journal Article Protective role for toll-like receptor-9 in the development of atherosclerosis in apolipoprotein e-deficient miceKoulis, Christine, Chen, Yung-Chih, Hausding, Christian, Ahrens, Ingo, Kyaw, Tin Soe, Tay, Christopher, Allen, Terri, Jandeleit-Dahm, Karin, Sweet, Matthew J., Akira, Shizuo, Bobik, Alexander, Peter, Karlheinz and Agrotis, Alex (2014). Protective role for toll-like receptor-9 in the development of atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 34 (3), 516-525. doi: 10.1161/ATVBAHA.113.302407 |
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2014 Journal Article Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4Yu, C.-H., Nguyen, T.T.K., Irvine, K.M., Sweet, M.J., Frazer, I.H. and Blumenthal, A. (2014). Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4. European Journal of Immunology, 44 (5), 1480-1490. doi: 10.1002/eji.201343959 |
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2013 Journal Article The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteinsUllah, M. Obayed, Ve, Thomas, Mangan, Matthew, Alaidarous, Mohammed, Sweet, Matthew J., Mansell, Ashley and Kobe, Bostjan (2013). The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins. Acta Crystallographica Section D: Biological Crystallography, 69 (12), 2420-2430. doi: 10.1107/S0907444913022385 |
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2013 Journal Article Mechanism of bacterial interference with TLR4 signaling by Brucella TIR-domain-containing protein TcpBAlaidarous, Mohammed Abdullah, Ve, Thomas, Casey, Lachlan, Valkov, Eugene, Ericsson, Daniel, Obayed, Ullah, M., Schembri, Mark A., Mansell, Ashley, Sweet, Matthew J. and Kobe, Bostjan (2013). Mechanism of bacterial interference with TLR4 signaling by Brucella TIR-domain-containing protein TcpB. Journal of Biological Chemistry, 289 (2), 654-668. doi: 10.1074/jbc.M113.523274 |
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2013 Journal Article An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammationHohenhaus, Daniel M., Schaale, Kolja, Le Cao, Kim-Anh, Seow, Vernon, Iyer, Abishek, Fairlie, David P. and Sweet, Matthew J. (2013). An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation. Immunobiology, 218 (11), 1345-1353. doi: 10.1016/j.imbio.2013.07.001 |
