2015 Journal Article HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombiAhrens, Ingo, Chen, Yung-Chih, Topcic, Danijal, Bode, Michael, Haenel, David, Hagemeyer, Christoph E., Seeba, Hannah, Duerschmied, Daniel, Bassler, Nicole, Jandeleit-Dahm, Karin A., Sweet, Matthew J., Agrotis, Alex, Bobik, Alex and Peter, Karlheinz (2015). HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi. Thrombosis and Haemostasis, 114 (5), 994-1003. doi: 10.1160/TH14-12-1073 |
2015 Journal Article Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.Sester, David P., Sagulenko, Vitaliya, Thygesen, Sara J., Cridland, Jasmyn A., Loi, Yen Siew, Cridland, Simon O., Masters, Seth L., Genske, Ulrich, Hornung, Veit, Andoniou, Christopher E., Sweet, Matthew J., Degli-Esposti, Mariapia A., Schroder, Kate and Stacey, Katryn J. (2015). Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.. Journal of Immunology, 195 (3), 1233-1241. doi: 10.4049/jimmunol.1402859 |
2015 Journal Article Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: a ticking time bomb in ageingKapetanovic, Ronan, Bokil, Nilesh J. and Sweet, Matthew J. (2015). Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: a ticking time bomb in ageing. Ageing Research Reviews, 24 (Pt A), 40-53. doi: 10.1016/j.arr.2015.02.005 |
2015 Journal Article The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host–pathogen interactionsMavromatis, Charalampos (Harris), Bokil, Nilesh J., Totsika, Makrina, Kakkanat, Asha, Schaale, Kolja, Cannistraci, Carlo V., Ryu, Taewoo, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A., Sweet, Matthew J. and Ravasi, Timothy (2015). The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host–pathogen interactions. Cellular Microbiology, 17 (5), 730-746. doi: 10.1111/cmi.12397 |
2014 Journal Article Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migrationIrvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014). Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 (47), 17851-17862. doi: 10.3748/wjg.v20.i47.17851 |
2014 Journal Article Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiationKwa, Mei Qi, Huynh, Jennifer, Aw, Jiamin, Zhang, Lianyi, Nguyen, Thao, Reynolds, Eric C., Sweet, Matthew J., Hamilton, John A. and Scholz, Glen M. (2014). Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation. Journal of Biological Chemistry, 289 (45), 31077-31087. doi: 10.1074/jbc.M114.589382 |
2014 Journal Article The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella ChallengeChen, Kaiwen W., Groß, Christina J., Vasquez Sotomayor, Flor, Stacey, Katryn J., Tschopp, Jurg, Sweet, Matthew J. and Schroder, Kate (2014). The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge. Cell Reports, 8 (2), 570-582. doi: 10.1016/j.celrep.2014.06.028 |
2014 Journal Article Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cellsKwa, Mei Qi, Nguyen, Thao, Huynh, Jennifer, Ramnath, Divya, De Nardo, Dominic, Lam, Pei Yeng, Reynolds, Eric C., Hamilton, John A., Sweet, Matthew J. and Scholz, Glen M. (2014). Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cells. Journal of Biological Chemistry, 289 (28), 19758-19768. doi: 10.1074/jbc.M114.584540 |
2014 Journal Article Towards selective lysophospholipid GPCR modulatorsArchbold, Julia K., Martin, Jennifer L. and Sweet, Matthew J. (2014). Towards selective lysophospholipid GPCR modulators. Trends in Pharmacological Sciences, 35 (5), 219-226. doi: 10.1016/j.tips.2014.03.004 |
2014 Journal Article Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasisSchroder, Wayne A., Major, Lee D., Le, Thuy T., Gardner, Joy, Sweet, Matthew J., Janciauskiene, Sabina and Suhrbier, Andreas (2014). Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis. Cancer Medicine, 3 (3), 500-513. doi: 10.1002/cam4.229 |
2014 Journal Article Protective role for toll-like receptor-9 in the development of atherosclerosis in apolipoprotein e-deficient miceKoulis, Christine, Chen, Yung-Chih, Hausding, Christian, Ahrens, Ingo, Kyaw, Tin Soe, Tay, Christopher, Allen, Terri, Jandeleit-Dahm, Karin, Sweet, Matthew J., Akira, Shizuo, Bobik, Alexander, Peter, Karlheinz and Agrotis, Alex (2014). Protective role for toll-like receptor-9 in the development of atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 34 (3), 516-525. doi: 10.1161/ATVBAHA.113.302407 |
2014 Journal Article Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4Yu, C.-H., Nguyen, T.T.K., Irvine, K.M., Sweet, M.J., Frazer, I.H. and Blumenthal, A. (2014). Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4. European Journal of Immunology, 44 (5), 1480-1490. doi: 10.1002/eji.201343959 |
2013 Journal Article The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteinsUllah, M. Obayed, Ve, Thomas, Mangan, Matthew, Alaidarous, Mohammed, Sweet, Matthew J., Mansell, Ashley and Kobe, Bostjan (2013). The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins. Acta Crystallographica Section D: Biological Crystallography, 69 (12), 2420-2430. doi: 10.1107/S0907444913022385 |
2013 Journal Article Mechanism of bacterial interference with TLR4 signaling by Brucella TIR-domain-containing protein TcpBAlaidarous, Mohammed Abdullah, Ve, Thomas, Casey, Lachlan, Valkov, Eugene, Ericsson, Daniel, Obayed, Ullah, M., Schembri, Mark A., Mansell, Ashley, Sweet, Matthew J. and Kobe, Bostjan (2013). Mechanism of bacterial interference with TLR4 signaling by Brucella TIR-domain-containing protein TcpB. Journal of Biological Chemistry, 289 (2), 654-668. doi: 10.1074/jbc.M113.523274 |
2013 Journal Article An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammationHohenhaus, Daniel M., Schaale, Kolja, Le Cao, Kim-Anh, Seow, Vernon, Iyer, Abishek, Fairlie, David P. and Sweet, Matthew J. (2013). An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation. Immunobiology, 218 (11), 1345-1353. doi: 10.1016/j.imbio.2013.07.001 |
2013 Journal Article Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpBAlaidarous, Mohammed, Ve, Thomas, Ullah, M. Obayed, Valkov, Eugene, Mansell, Ashley, Schembri, Mark A., Sweet, Matthew J. and Kobe, Bostjan (2013). Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69 (10), 1167-1170. doi: 10.1107/S1744309113024408 |
2013 Journal Article Inflammatory Responses Induced by Lipopolysaccharide Are Amplified in Primary Human Monocytes but Suppressed in Macrophages by Complement Protein C5aSeow, Vernon, Lim, Junxian, Iyer, Abishek, Suen, Jacky Y., Ariffin, Juliana K., Hohenhaus, Daniel M., Sweet, Matthew J. and Fairlie, David P. (2013). Inflammatory Responses Induced by Lipopolysaccharide Are Amplified in Primary Human Monocytes but Suppressed in Macrophages by Complement Protein C5a. Journal of Immunology, 191 (8), 4308-4316. doi: 10.4049/jimmunol.1301355 |
2013 Journal Article An antioxidant role for catecholate siderophores in SalmonellaAchard, Maud E. S, Chen, Kaiwen W., Sweet, Matthew J., Watts, Rebecca E., Schroder, Kate, Schembri, Mark A. and McEwan, Alastair G. (2013). An antioxidant role for catecholate siderophores in Salmonella. Biochemical Journal, 454 (3), 543-549. doi: 10.1042/BJ20121771 |
2013 Journal Article Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copperStafford, Sian L., Bokil, Nilesh J., Achard, Maud E. S., Kapetanovic, Ronan, Schembri, Mark A., McEwan, Alastair G. and Sweet, Matthew J. (2013). Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper. Bioscience Reports, 33 (4) ARTN e00049, 541-554. doi: 10.1042/BSR20130014 |
2013 Journal Article Crystallization and X-ray diffraction analysis of the N-terminal domain of the Toll-like receptor signalling adaptor protein TRIF/TICAM-1Ullah, M. Obayed, Ve, Thomas, Dkhar, Jameris, Alaidarous, Mohammed, Ericsson, Daniel J., Sweet, Matthew J., Mansell, Ashley and Kobe, Bostjan (2013). Crystallization and X-ray diffraction analysis of the N-terminal domain of the Toll-like receptor signalling adaptor protein TRIF/TICAM-1. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69 (7), 766-770. doi: 10.1107/S174430911301419X |