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2021 Journal Article Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanomaJacquelot, Nicolas, Seillet, Cyril, Wang, Minyu, Pizzolla, Angela, Liao, Yang, Hediyeh-zadeh, Soroor, Grisaru-Tal, Sharon, Louis, Cynthia, Huang, Qiutong, Schreuder, Jaring, Souza-Fonseca-Guimaraes, Fernando, de Graaf, Carolyn A., Thia, Kevin, Macdonald, Sean, Camilleri, Mary, Luong, Kylie, Zhang, Shengbo, Chopin, Michael, Molden-Hauer, Tristan, Nutt, Stephen L., Umansky, Viktor, Ciric, Bogoljub, Groom, Joanna R., Foster, Paul S., Hansbro, Philip M., McKenzie, Andrew N. J., Gray, Daniel H. D., Behren, Andreas, Cebon, Jonathan ... Belz, Gabrielle T. (2021). Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma. Nature Immunology, 22 (7), 851-864. doi: 10.1038/s41590-021-00943-z |
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2020 Journal Article Natural killer cell engineering – a new hope for cancer immunotherapyLin, Cheng-Yu, Gobius, Ilan and Souza-Fonseca-Guimaraes, Fernando (2020). Natural killer cell engineering – a new hope for cancer immunotherapy. Seminars in Hematology, 57 (4), 194-200. doi: 10.1053/j.seminhematol.2020.10.002 |
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2020 Journal Article The antitumor effect of heparin is not mediated by direct NK cell activationRossi, Gustavo R., Gonçalves, Jenifer P., McCulloch, Timothy, Delconte, Rebecca B., Hennessy, Robert J., Huntington, Nicholas D., Trindade, Edvaldo S. and Souza-Fonseca-Guimaraes, Fernando (2020). The antitumor effect of heparin is not mediated by direct NK cell activation. Journal of Clinical Medicine, 9 (8) 2666, 2666-11. doi: 10.3390/jcm9082666 |
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2020 Journal Article Harnessing natural killer immunity in metastatic SCLCBest, Sarah A., Hess, Jonas B., Souza-Fonseca-Guimaraes, Fernando, Cursons, Joseph, Kersbergen, Ariena, Dong, Xueyi, Rautela, Jai, Hyslop, Stephanie R., Ritchie, Matthew E., Davis, Melissa J., Leong, Tracy L., Irving, Louis, Steinfort, Daniel, Huntington, Nicholas D. and Sutherland, Kate D. (2020). Harnessing natural killer immunity in metastatic SCLC. Journal of Thoracic Oncology, 15 (9), 1507-1521. doi: 10.1016/j.jtho.2020.05.008 |
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2020 Journal Article Erratum:NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS (Journal of Experimental Medicine (2020) 217:5 DOI: 10.1084/jem.20191421)Louis, Cynthia, Souza-Fonseca-Guimaraes, Fernando, Yang, Yuyan, D'Silva, Damian, Kratina, Tobias, Dagley, Laura, Hediyeh-Zadeh, Soroor, Rautela, Jai, Masters, Seth Lucian, Davis, Melissa J., Babon, Jeffrey J., Ciric, Bogoljub, Vivier, Eric, Alexander, Warren S., Huntington, Nicholas D. and Wicks, Ian P. (2020). Erratum:NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS (Journal of Experimental Medicine (2020) 217:5 DOI: 10.1084/jem.20191421). Journal of Experimental Medicine, 217 (5) e2019142103192020c. doi: 10.1084/jem.2019142103192020c |
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2020 Journal Article Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating AntibodiesChew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019 |
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2020 Journal Article NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CISLouis, Cynthia, Souza-Fonseca-Guimaraes, Fernando, Yang, Yuyan, D’Silva, Damian, Kratina, Tobias, Dagley, Laura, Hediyeh-Zadeh, Soroor, Rautela, Jai, Masters, Seth Lucian, Davis, Melissa J., Babon, Jeffrey J., Ciric, Bogoljub, Vivier, Eric, Alexander, Warren S., Huntington, Nicholas D. and Wicks, Ian P. (2020). NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS. Journal of Experimental Medicine, 217 (5) e20191421. doi: 10.1084/jem.20191421 |
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2020 Journal Article NK cell priming from endogenous homeostatic signals is modulated by CISDelconte, Rebecca B., Guittard, Geoffrey, Goh, Wilford, Hediyeh-Zadeh, Soroor, Hennessy, Robert J., Rautela, Jai, Davis, Melissa J., Souza-Fonseca-Guimaraes, Fernando, Nunes, Jacques A. and Huntington, Nicholas D. (2020). NK cell priming from endogenous homeostatic signals is modulated by CIS. Frontiers in Immunology, 11 75, 75. doi: 10.3389/fimmu.2020.00075 |
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2020 Journal Article Tumor microenvironment-associated extracellular matrix components regulate NK cell functionRossi, Gustavo Rodrigues, Trindade, Edvaldo S. and Souza-Fonseca-Guimaraes, Fernando (2020). Tumor microenvironment-associated extracellular matrix components regulate NK cell function. Frontiers in Immunology, 11 73, 73. doi: 10.3389/fimmu.2020.00073 |
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2019 Journal Article Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cellsRautela, Jai, Dagley, Laura F., Kratina, Tobias, Anthony, Angaleena, Goh, Wilford, Surgenor, Elliot, Delconte, Rebecca B., Webb, Andrew I., Elwood, Ngaire, Groom, Joanna R., Souza-Fonseca-Guimaraes, Fernando, Corcoran, Lynn and Huntington, Nicholas D. (2019). Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells. Molecular Immunology, 115, 56-63. doi: 10.1016/j.molimm.2018.08.017 |
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2019 Journal Article Therapeutic blockade of activin-A improves NK cell function and antitumor immunityRautela, Jai, Dagley, Laura F., de Oliveira, Carolina C., Schuster, Iona S., Hediyeh-Zadeh, Soroor, Delconte, Rebecca B., Cursons, Joseph, Hennessy, Robert, Hutchinson, Dana S., Harrison, Craig, Kita, Badia, Vivier, Eric, Webb, Andrew I., Degli-Esposti, Mariapia A., Davis, Melissa J., Huntington, Nicholas D. and Souza-Fonseca-Guimaraes, Fernando (2019). Therapeutic blockade of activin-A improves NK cell function and antitumor immunity. Science Signaling, 12 (596) aat7527, eaat7527. doi: 10.1126/scisignal.aat7527 |
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2019 Journal Article A gene signature predicting natural killer cell infiltration and improved survival in melanoma patientsCursons, Joseph, Souza-Fonseca-Guimaraes, Fernando, Foroutan, Momeneh, Anderson, Ashley, Hollande, Frédéric, Hediyeh-Zadeh, Soroor, Behren, Andreas, Huntington, Nicholas D. and Davis, Melissa J. (2019). A gene signature predicting natural killer cell infiltration and improved survival in melanoma patients. Cancer Immunology Research, 7 (7), 1162-1174. doi: 10.1158/2326-6066.cir-18-0500 |
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2019 Journal Article Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-βHealy, Lachlan P., Rossi, Gustavo R., Rautela, Jai, Slade, Charlotte A., Huntington, Nicholas D., Winship, Ingrid M. and Souza-Fonseca-Guimaraes, Fernando (2019). Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β. Frontiers in Immunology, 10 (MAY) 904. doi: 10.3389/fimmu.2019.00904 |
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2019 Journal Article A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapyLelliott, Emily J., Cullinane, Carleen, Martin, Claire A., Walker, Rachael, Ramsbottom, Kelly M., Souza-Fonseca-Guimaraes, Fernando, Abuhammad, Shatha, Michie, Jessica, Kirby, Laura, Young, Richard J., Slater, Alison, Lau, Peter, Meeth, Katrina, Oliaro, Jane, Haynes, Nicole, McArthur, Grant A. and Sheppard, Karen E. (2019). A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy. Scientific Reports, 9 (1) 1225. doi: 10.1038/s41598-018-37883-y |
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2019 Journal Article The Emergence of Natural Killer Cells as a Major Target in Cancer ImmunotherapySouza-Fonseca-Guimaraes, Fernando, Cursons, Joseph and Huntington, Nicholas D. (2019). The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy. Trends in Immunology, 40 (2), 142-158. doi: 10.1016/j.it.2018.12.003 |
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2019 Journal Article Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on “Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study”Briassoulis, George, Briassoulis, Panagiotis, Miliaraki, Marianna, Ilia, Stavroula, Parlato, Marianna, Philippart, François, Rouquette, Alexandra, Moucadel, Virginie, Cavaillon, Jean-Marc, Misset, Benoît, Combined Approach for The eArly diagnosis of INfection in sepsis (CAPTAIN) study group and Guimaraes, Fernando (2019). Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on “Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study”. Intensive Care Medicine, 45 (1), 132-133. doi: 10.1007/s00134-018-5451-y |
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2019 Journal Article Context-dependent role for T-bet in T follicular helper differentiation and germinal center function following viral infectionSheikh, Amania A., Cooper, Lucy, Feng, Meiqi, Souza-Fonseca-Guimaraes, Fernando, Lafouresse, Fanny, Duckworth, Brigette C., Huntington, Nicholas D., Moon, James J., Pellegrini, Marc, Nutt, Stephen L., Belz, Gabrielle T., Good-Jacobson, Kim L. and Groom, Joanna R. (2019). Context-dependent role for T-bet in T follicular helper differentiation and germinal center function following viral infection. Cell Reports, 28 (7), 1758-1772.e4. doi: 10.1016/j.celrep.2019.07.034 |
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2018 Journal Article NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel diseaseTye, Hazel, Yu, Chien-Hsiung, Simms, Lisa A., de Zoete, Marcel R., Kim, Man Lyang, Zakrzewski, Martha, Penington, Jocelyn S., Harapas, Cassandra R., Souza-Fonseca-Guimaraes, Fernando, Wockner, Leesa F., Preaudet, Adele, Mielke, Lisa A., Wilcox, Stephen A., Ogura, Yasunori, Corr, Sinead C., Kanojia, Komal, Kouremenos, Konstantinos A., De Souza, David P., McConville, Malcolm J., Flavell, Richard A., Gerlic, Motti, Kile, Benjamin T., Papenfuss, Anthony T., Putoczki, Tracy L., Radford-Smith, Graham L. and Masters, Seth L. (2018). NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease. Nature Communications, 9 (1) 3728, 3728. doi: 10.1038/s41467-018-06125-0 |
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2018 Journal Article Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomesJiao, Yuhao, Davis, Joanne E., Rautela, Jai, Carrington, Emma M., Ludford-Menting, Mandy J., Goh, Wilford, Delconte, Rebecca B., Souza-Fonseca-Guimaraes, Fernando, Koldej, Rachel, Gray, Daniel, Huang, David, Kile, Ben T., Lew, Andrew M., Ritchie, David S. and Huntington, Nicholas D. (2018). Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes. Cell Death & Differentiation, 26 (8), 1516-1530. doi: 10.1038/s41418-018-0228-y |
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2018 Journal Article GM-CSF quantity has a selective effect on granulocytic vs. monocytic myeloid development and functionSun, Li, Rautela, Jai, Delconte, Rebecca B., Souza-Fonseca-Guimaraes, Fernando, Carrington, Emma M., Schenk, Robyn L., Herold, Marco J., Huntington, Nicholas D., Lew, Andrew M., Xu, Yuekang and Zhan, Yifan (2018). GM-CSF quantity has a selective effect on granulocytic vs. monocytic myeloid development and function. Frontiers in Immunology, 9 1922. doi: 10.3389/fimmu.2018.01922 |
