Overview
Background
Dr Baxter is a Research Fellow at the Queensland Centre for Gynaecological Cancer (QCGC) Research. The major theme of her research is to identify and validate biomarkers that improve outcomes for females with gynaecological cancer, particularly endometrial cancer. Dr Baxter leads the translational studies for two clinical trials: the recently completed feMMe phase II randomised clinical trial which showed that approximately 60% of females with early-stage endometrial cancer can safely avoid a hysterectomy and instead undergo hormonal (intrauterine progestin) treatment (NCT01686126), and the ongoing ENDO-3 phase III randomised clinical trial which explores the risks and benefits of sentinel node biopsy in early-stage endometrial cancer (NCT04073706).
Availability
- Dr Eva Baxter is:
- Available for supervision
- Media expert
Qualifications
- Doctor of Philosophy, University of Edinburgh
Research interests
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Endometrial cancer
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Biomarkers
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Molecular biology
Works
Search Professor Eva Baxter’s works on UQ eSpace
2025
Journal Article
A Phase 2b, open-label, single arm, multicentre, pilot study of the efficacy, safety and tolerability of dostarlimab in women with early-stage MMR deficient endometrioid endometrial adenocarcinoma
Obermair, A., Gebski, V., Goh, J., Kuchel, A., Brand, A., Mak, B., McNally, O., Baxter, E., Jobling, T. and Mileshkin, L. (2025). A Phase 2b, open-label, single arm, multicentre, pilot study of the efficacy, safety and tolerability of dostarlimab in women with early-stage MMR deficient endometrioid endometrial adenocarcinoma. International Journal of Gynecological Cancer, 35 (4) 101644, 101644. doi: 10.1016/j.ijgc.2025.101644
2024
Conference Publication
EV430/#358 Benefit-harm trade-off for groin node dissection versus groin ultrasound monitoring to reduce the risk of surgery-related morbidity in vulvar cancer – a decision-tree analysis
Obermair, Andreas, West, Zoe, Baxter, Eva, Condous, George, Hacker, Neville, Lord, Sally, Mccarthy, Sandie, Janda, Monika, Tuffaha, Haitham, Hayes, Sandi, Disipio, Tracey, Mellon, Anne, Gebski, Val, Mcnally, Orla and Martin, Andrew (2024). EV430/#358 Benefit-harm trade-off for groin node dissection versus groin ultrasound monitoring to reduce the risk of surgery-related morbidity in vulvar cancer – a decision-tree analysis. IGCS 2024 Annual Meeting, Dublin, Ireland, 16-18 October 2024. London, United Kingdom: BMJ Group. doi: 10.1136/ijgc-2024-igcs.551
2021
Journal Article
A phase III randomized clinical trial comparing sentinel node biopsy with no retroperitoneal node dissection in apparent early-stage endometrial cancer – ENDO-3: ANZGOG trial 1911/2020
Obermair, Andreas, Nicklin, Jim, Gebski, Val, Hayes, Sandra C., Graves, Nicholas, Mileshkin, Linda, Lin, Ming Yin, Beale, Phillip, Baxter, Eva, Robledo, Kristy, Salomon, Carlos, Hanna, George B. and Janda, Monika (2021). A phase III randomized clinical trial comparing sentinel node biopsy with no retroperitoneal node dissection in apparent early-stage endometrial cancer – ENDO-3: ANZGOG trial 1911/2020. International Journal of Gynecologic Cancer, 31 (12) ijgc-2021-003029, 1595-1601. doi: 10.1136/ijgc-2021-003029
2020
Journal Article
Fertility-sparing treatment in early endometrial cancer: current state and future strategies
Obermair, Andreas, Baxter, Eva, Brennan, Donal J., McAlpine, Jessica N., Muellerer, Jennifer J., Amant, Frédéric, van Gent, Mignon D. J. M., Coleman, Robert L., Westin, Shannon N., Yates, Melinda S., Krakstad, Camilla and Janda, Monika (2020). Fertility-sparing treatment in early endometrial cancer: current state and future strategies. Obstetrics and Gynecology Science, 63 (4), 417-431. doi: 10.5468/ogs.19169
2020
Journal Article
Improving response to progestin treatment of low-grade endometrial cancer
Baxter, Eva, Brennan, Donal J, McAlpine, Jessica N, Mueller, Jennifer J, Amant, Frédéric, van Gent, Mignon D J M, Huntsman, David G, Coleman, Robert L, Westin, Shannon N, Yates, Melinda S, Krakstad, Camilla, Quinn, Michael A, Janda, Monika and Obermair, Andreas (2020). Improving response to progestin treatment of low-grade endometrial cancer. International Journal of Gynecologic Cancer, 30 (11) ijgc-2020-001309, ijgc-2020. doi: 10.1136/ijgc-2020-001309
2020
Journal Article
Mitogen-Activated Protein Kinase (MAPK) and Obesity-Related Cancer
Donohoe, Fionán, Wilkinson, Michael, Baxter, Eva and Brennan, Donal J. (2020). Mitogen-Activated Protein Kinase (MAPK) and Obesity-Related Cancer. International Journal of Molecular Sciences, 21 (4) 1241, 1-19. doi: 10.3390/ijms21041241
2020
Journal Article
G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome
Casciello, Francesco, Al-Ejeh, Fares, Miranda, Mariska, Kelly, Greg, Baxter, Eva, Windloch, Karolina, Gannon, Frank and Lee, Jason S. (2020). G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome. Theranostics, 10 (10), 4515-4529. doi: 10.7150/thno.41453
2019
Journal Article
Molecular basis of distinct oestrogen responses in endometrial and breast cancer
Baxter, Eva, Windloch, Karolina, Kelly, Greg, Lee, Jason S., Gannon, Frank and Brennan, Donal (2019). Molecular basis of distinct oestrogen responses in endometrial and breast cancer. Endocrine-Related Cancer, 26 (1), 31-46. doi: 10.1530/ERC-17-0563
2018
Journal Article
Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation
Jacquelin, Sebastien, Straube, Jasmin, Cooper, Leanne, Vu, Therese, Song, Axia, Bywater, Megan, Baxter, Eva, Heidecker, Matthew, Wackrow, Brad, Porter, Amy, Ling, Victoria, Green, Joanne, Austin, Rebecca, Kazakoff, Stephen, Waddell, Nicola, Hesson, Luke B., Pimanda, John E., Stegelmann, Frank, Bullinger, Lars, Döhner, Konstanze, Rampal, Raajit K., Heckl, Dirk, Hill, Geoffrey R. and Lane, Steven W. (2018). Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation. Blood, 132 (26), blood-2018. doi: 10.1182/blood-2018-04-846220
2016
Journal Article
Surgical safety and personal costs in morbidly obese, multimorbid patients diagnosed with early-stage endometrial cancer having a hysterectomy
Obermair, Andreas, Brennan, Donal J., Baxter, Eva, Armes, Jane E., Gebski, Val and Janda, Monika (2016). Surgical safety and personal costs in morbidly obese, multimorbid patients diagnosed with early-stage endometrial cancer having a hysterectomy. Gynecologic Oncology Research and Practice, 3 (1), 1. doi: 10.1186/s40661-016-0023-8
2014
Journal Article
Epigenetic regulation in cancer progression
Baxter, Eva, Windloch, Karolina, Gannon, Frank and Lee, Jason S. (2014). Epigenetic regulation in cancer progression. Cell & Bioscience, 4 (1) 45, 45. doi: 10.1186/2045-3701-4-45
Funding
Current funding
Supervision
Availability
- Dr Eva Baxter is:
- Available for supervision
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Available projects
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Improving Quality of Survival for Women with Gynaecological Cancer
Gynaecological cancers are the third most common cancer type diagnosed in Australian women. Each year over 6,700 Australian women and girls are diagnosed with gynaecological cancer and almost a third will not survive their disease.
PhD scholarships are available for exceptional students to complete a PhD as part of a National Health and Medical Research Council Centre of Research Excellence (CRE) in Improving the Quality of Survival for Gynaecological Cancer Patients. The aim of this CRE is to address contemporary issues in gynaecological cancer care, with a focus on three priority areas: 1) enabling fertility after endometrial cancer; 2) reducing lymphoedema; and 3) optimising cancer recovery.
We have three full-time PhD opportunities available focusing on improving quality of life, health, and function during and after gynaecological cancer treatment, with a focus on biomarker research, implementation research and cancer survivorship.
Supervision history
Current supervision
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Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Associate Advisor
Other advisors: Dr Zoe West, Professor Andrew Martin, Professor Andreas Obermair
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Master Philosophy
Patterns of care in endometrial cancer management in Queensland: a retrospective analysis.
Associate Advisor
Other advisors: Professor Andreas Obermair
Media
Enquiries
Contact Dr Eva Baxter directly for media enquiries about:
- Biomarkers
- Endometrial cancer
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