Overview
Background
Dr Zoe West is a Research Fellow at The University of Queensland's Frazer Institute, within the Queensland Centre for Gynaecological Cancer Research group. Her research focuses on vulvar cancer, with the goal of improving treatment outcomes and expanding therapeutic options through more personalised approaches to care. Her work integrates multi-omics and translational research to better understand the biological drivers of vulvar cancer and support the development of improved patient-centred treatments.
Availability
- Dr Zoe West is:
- Available for supervision
Qualifications
- Doctor of Philosophy of Cellular Immunology, Queensland University of Technology
Research interests
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Vulvar Cancer
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Gynaecological Cancers
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3D imaging
iDISCO - DIPCO
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Tumour microenvironment
Immune-oncology - Cellular interactions
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Microscopy
Light sheet - Confocal - AI segmentation
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Spatial transcriptomics
Works
Search Professor Zoe West’s works on UQ eSpace
2025
Journal Article
Extracellular vesicles as biomarkers for endometrial cancer – a systematic review
Baxter, Eva, Nair, Soumyalekshmi, West, Zoe, Salomon, Carlos and Obermair, Andreas (2025). Extracellular vesicles as biomarkers for endometrial cancer – a systematic review. Translational Oncology, 62 102543, 1-10. doi: 10.1016/j.tranon.2025.102543
2025
Journal Article
Patterns of care for vulval cancer treatment: the Queensland experience
Davie, Stacey, Obermair, Andreas and West, Zoe Elizabeth (2025). Patterns of care for vulval cancer treatment: the Queensland experience. International Journal of Gynecological Cancer, 35 (7) 101956, 101956-101956. doi: 10.1016/j.ijgc.2025.101956
2025
Conference Publication
2D and 3D spatial characterisation of tertiary lymphoid structures in head and neck cancer patients receiving immune checkpoint blockade therapy
Donovan, Meg L., Sadeghirad, Habib, Berrell, Naomi, Monkman, James, Naei, Vahid Yaghoubi, Tan, Chin Wee, Yunis, Joseph, West, Zoe, Warkiani, Majid E., Ladwa, Rahul, Hughes, Brett G., Da Gama Duarte, Jessica and Kulasinghe, Arutha (2025). 2D and 3D spatial characterisation of tertiary lymphoid structures in head and neck cancer patients receiving immune checkpoint blockade therapy. AACR Annual Meeting 2025, Chicago, IL United States, 25-30 April 2025. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2025-5252
2024
Journal Article
Whole-brain spatial transcriptional analysis at cellular resolution
Kanatani, Shigeaki, Kreutzmann, Judith C., Li, Yue, West, Zoe, Larsen, Lea Lydolph, Nikou, Danai Vougesi, Eidhof, Ilse, Walton, Abigail, Zhang, Songbai, Rodríguez-Kirby, Leslie Rubio, Skytte, Jacob Lercke, Salinas, Casper Gravesen, Takamatsu, Kimiharu, Li, Xiaofei, Tanaka, Daisuke H., Kaczynska, Dagmara, Fukumoto, Keishiro, Karamzadeh, Razieh, Xiang, Yujiao, Uesaka, Naofumi, Tanabe, Tsutomu, Adner, Mikael, Hartman, Johan, Miyakawa, Ayako, Sundström, Erik, Castelo-Branco, Gonçalo, Roostalu, Urmas, Hecksher-Sørensen, Jacob and Uhlén, Per (2024). Whole-brain spatial transcriptional analysis at cellular resolution. Science, 386 (6724), 907-915. doi: 10.1126/science.adn9947
2024
Conference Publication
EV430/#358 Benefit-harm trade-off for groin node dissection versus groin ultrasound monitoring to reduce the risk of surgery-related morbidity in vulvar cancer – a decision-tree analysis
Obermair, Andreas, West, Zoe, Baxter, Eva, Condous, George, Hacker, Neville, Lord, Sally, Mccarthy, Sandie, Janda, Monika, Tuffaha, Haitham, Hayes, Sandi, Disipio, Tracey, Mellon, Anne, Gebski, Val, Mcnally, Orla and Martin, Andrew (2024). EV430/#358 Benefit-harm trade-off for groin node dissection versus groin ultrasound monitoring to reduce the risk of surgery-related morbidity in vulvar cancer – a decision-tree analysis. IGCS 2024 Annual Meeting, Dublin, Ireland, 16-18 October 2024. London, United Kingdom: BMJ Group. doi: 10.1136/ijgc-2024-igcs.551
2024
Journal Article
Three-dimensional imaging of upper tract urothelial carcinoma improves diagnostic yield and accuracy
Fukumoto, Keishiro, Kanatani, Shigeaki, Jaremko, Georg, West, Zoe, Li, Yue, Takamatsu, Kimiharu, Al Rayyes, Ibrahim, Mikami, Shuji, Niwa, Naoya, Axelsson, Tomas Andri, Tanaka, Nobuyuki, Oya, Mototsugu, Miyakawa, Ayako, Brehmer, Marianne and Uhlén, Per (2024). Three-dimensional imaging of upper tract urothelial carcinoma improves diagnostic yield and accuracy. JCI Insight, 9 (14) e175751. doi: 10.1172/jci.insight.175751
2022
Journal Article
Disrupted Cacna1c gene expression perturbs spontaneous Ca <sup>2+</sup> activity causing abnormal brain development and increased anxiety
Smedler, Erik, Louhivuori, Lauri, Romanov, Roman A., Masini, Débora, Dehnisch Ellström, Ivar, Wang, Chungliang, Caramia, Martino, West, Zoe, Zhang, Songbai, Rebellato, Paola, Malmersjö, Seth, Brusini, Irene, Kanatani, Shigeaki, Fisone, Gilberto, Harkany, Tibor and Uhlén, Per (2022). Disrupted Cacna1c gene expression perturbs spontaneous Ca 2+ activity causing abnormal brain development and increased anxiety. Proceedings of the National Academy of Sciences, 119 (7) e2108768119. doi: 10.1073/pnas.2108768119
2021
Journal Article
The trans-SNARE complex VAMP4/Stx6/Stx7/Vti1b is a key regulator of Golgi to late endosome MT1-MMP transport in macrophages
West, Zoe Elizabeth, Aitcheson, Savannah Margaret, Semmler, Annalese Barbara Trudy and Murray, Rachael Zoe (2021). The trans-SNARE complex VAMP4/Stx6/Stx7/Vti1b is a key regulator of Golgi to late endosome MT1-MMP transport in macrophages. Traffic, 22 (11), 368-376. doi: 10.1111/tra.12813
2019
Journal Article
Development and use of biomaterials as wound healing therapies
Murray, Rachael Zoe, West, Zoe Elizabeth, Cowin, Allison June and Farrugia, Brooke Louise (2019). Development and use of biomaterials as wound healing therapies. Burns & Trauma, 7, 1-9. doi: 10.1186/s41038-018-0139-7
2019
Journal Article
Invasion by activated macrophages requires delivery of nascent membrane-type-1 matrix metalloproteinase through late endosomes/lysosomes to the cell surface
Röhl, Joan, West, Zoe E., Rudolph, Maren, Zaharia, Andreea, Van Lonkhuyzen, Derek, Hickey, Danica K., Semmler, Annalese B. T. and Murray, Rachael Z. (2019). Invasion by activated macrophages requires delivery of nascent membrane-type-1 matrix metalloproteinase through late endosomes/lysosomes to the cell surface. Traffic, 20 (9) tra.12675, 661-673. doi: 10.1111/tra.12675
2017
Journal Article
Altered macrophage phenotypes impair wound healing
Sahin, K. B., Hesketh, M., West, Z. E. and Murray, R. Z. (2017). Altered macrophage phenotypes impair wound healing. Wound Practice and Research, 25 (4), 166-171.
2017
Journal Article
Macrophage phenotypes regulate scar formation and chronic wound healing
Hesketh, Mark, Sahin, Katherine B., West, Zoe E. and Murray, Rachael Z. (2017). Macrophage phenotypes regulate scar formation and chronic wound healing. International Journal of Molecular Sciences, 18 (7) 1545, 1-10. doi: 10.3390/ijms18071545
Funding
Past funding
Supervision
Availability
- Dr Zoe West is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Available projects
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Biomarkers in Gynaecological Cancer
Gynaecological cancers are the third most common cancer type diagnosed in Australian women. Each year over 6,700 Australian women and girls are diagnosed with gynaecological cancer and almost a third will not survive their disease.
We have a full-time PhD opportunity available at QCGC Research focusing on discovering and validating biomarkers that improve outcomes for women with gynaecological cancer. This project will involve working with clinical samples, conducting laboratory work, and analysing data.
The successful applicant will work as part of the QCGC Research team at UQCCR, as well as collaborate with researchers, clinicians, consumers, and stakeholders from other organisations, including hospitals, pathology providers and the community.
Supervision history
Current supervision
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Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Associate Advisor
Other advisors: Dr Eva Baxter, Professor Andrew Martin, Professor Andreas Obermair
Media
Enquiries
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