
Overview
Background
Dr Malcolm Lim is an experienced Cancer Biologist and His research interest spans cancer biology, biomarker discovery and theranostic nanomedicine.
He received his PhD from the University of Queensland (UQ) in 2022. His research, conducted in the labs of Professors Sunil Lakhani and Kristofer Thurecht, involved evaluating the efficacy of using nanomedicine for precision delivery of chemo- or radiotherapeutics against biomarkers in brain metastases. For this work, he developed a clinically-relevant brain metastasis mouse model. His research was recognised with the UQ Dean’s Award for Outstanding Thesis 2022. (DOIs: 10.1021/acs.molpharmaceut.3c00558, 10.3791/64216)
Currently, Malcolm serves as a Postdoctoral Research Fellow at the ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals (AMTAR) and the Thurecht’s Lab at UQ-Centre for Advanced Imaging (CAI) in Australian Institute for Bioengineering and Nanotechnology (AIBN), where he will apply his multidisciplinary expertise to explore radiobiology and radiation-induced biological responses and to advance targeted pharmaceuticals for challenging cancers.
Prior to joining AMTAR, Malcolm served as a Postdoctoral Researcher where he investigated the molecular mechanisms underlying Early Breast Cancers at the Molecular Breast Pathology Lab, UQ-Centre for Clinical Research, under the mentorship of Professors Sunil Lakhani and Peter Simpson. Before his academic career, Malcolm had five years of experience as a histologist, which provided him with a broad skillset in the field.
Dr Malcolm’s research is well-documented in numerous publications in biomedical research journals despite his career stage, reflecting his passion to advancing cancer research.
Availability
- Dr Malcolm Lim is:
- Available for supervision
Fields of research
Qualifications
- Diploma of Biomedical Science, Republic Polytechnic
- Bachelor of Science, The University of Queensland
- Bachelor (Honours) of Cancer Cell Biology, The University of Queensland
- Doctor of Philosophy of Cancer Cell Biology, The University of Queensland
Research interests
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Brain metastasis
Mechanisms underpinning the development of brain metastasis and new therapeutic strategies, CNS-penetrating targeted therapeutics, metastatic animal models
Works
Search Professor Malcolm Lim’s works on UQ eSpace
2016
Journal Article
Characterization of anaplastic lymphoma kinase-positive medulloblastomas
Yan, Benedict, Kuick, Chik Hong, Lim, Malcolm, Yong, Min Hwee, Lee, Chi Kuen, Low, Sharon Y.Y., Low, David C.Y., Lim, Diana, Soh, Shui Yen and Chang, Kenneth T.E. (2016). Characterization of anaplastic lymphoma kinase-positive medulloblastomas. Journal of Clinical Neuroscience, 23, 120-122. doi: 10.1016/j.jocn.2015.08.017
2014
Journal Article
Platform comparison for evaluation of ALK protein immunohistochemical expression, genomic copy number and hotspot mutation status in neuroblastomas
Yan, Benedict, Kuick, Chik Hong, Lim, Malcolm, Venkataraman, Kavita, Tennakoon, Chandana, Loh, Eva, Lian, Derrick, Leong, May Ying, Lakshmanan, Manikandan, Tergaonkar, Vinay, Sung, Wing-Kin, Soh, Shui Yen and Chang, Kenneth T.E. (2014). Platform comparison for evaluation of ALK protein immunohistochemical expression, genomic copy number and hotspot mutation status in neuroblastomas. PLoS ONE, 9 (9) e106575, e106575. doi: 10.1371/journal.pone.0106575
2013
Journal Article
Identification of MET genomic amplification, protein expression and alternative splice isoforms in neuroblastomas
Yan, Benedict, Lim, Malcolm, Zhou, Lihan, Kuick, Chik Hong, Leong, May Ying, Yong, Kol Jia, Aung, LeLe, Salto-Tellez, Manuel and Chang, Kenneth T. E. (2013). Identification of MET genomic amplification, protein expression and alternative splice isoforms in neuroblastomas. Journal of Clinical Pathology, 66 (11), 985-991. doi: 10.1136/jclinpath-2012-201375
Funding
Current funding
Supervision
Availability
- Dr Malcolm Lim is:
- Available for supervision
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Available projects
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Radiosensitising metastatic breast cancers by targeting DNA repair
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HER3-targeting in brain metastasis
Media
Enquiries
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