Professor

Barbara Leggett

Email: 
Phone: 
+61 7 3362 0170

Availability

Professor Barbara Leggett is:
Available for supervision

Fields of research

Biological Sciences Psychology Sports science and exercise

Qualifications

  • Bachelor (Honours) of Medicine Surgery, The University of Queensland
  • Doctoral Diploma of Medicine, The University of Queensland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Physicians, Royal College of Physicians

Search Professor Barbara Leggett’s works on UQ eSpace

174 works between 1990 and 2025
All (174) Journal Article (126) Conference Publication (47) Book Chapter (1)

141 - 160 of 174 works

2000

Journal Article

Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis

Biemer-Huttmann, A. E., Walsh, M. D., McGuckin, M. A., Simms, L. A., Young, J., Leggett, B. A. and Jass, J. R. (2000). Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis. Clinical Cancer Research, 6 (5), 1909-1916.

Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis

2000

Conference Publication

p14-ARF and p16-INK4A - one locus, two genes frequently affected in sporadic colorectal cancer

Whitehall, V. L., Walsh, M., Jass, J. R., Young, J. P. and Leggett, B. A. (2000). p14-ARF and p16-INK4A - one locus, two genes frequently affected in sporadic colorectal cancer. Australian Gastroenterology Week 2000, Hobart, 18-21 Oct, 2000. Melbourn: Blackwell Scientific.

p14-ARF and p16-INK4A - one locus, two genes frequently affected in sporadic colorectal cancer

2000

Conference Publication

Juvenile polyposis lesions show clonal loss of SMAD4 in epithelial as well as stromal compartments, endorsing the "gatekeeper" not the "landscaper" hypothesis

Woodford-Richens, K., Williamson, J., Bevan, S., Young, J. P., Jass, J. R., Leggett, B. A., Frayling, I., Thway, Y., Hodgson, S., Kim, J., Iwama, T., Novelli, M., Sheer, D., Poulsom, R., Wright, N.A., Houlston, R. and Tomlinson, I. (2000). Juvenile polyposis lesions show clonal loss of SMAD4 in epithelial as well as stromal compartments, endorsing the "gatekeeper" not the "landscaper" hypothesis. Pathological Society of Great Britain & Ireland 181st Meeting, Nottingham, 12-14 Jul, 2000. England: John Wiley & Sons.

Juvenile polyposis lesions show clonal loss of SMAD4 in epithelial as well as stromal compartments, endorsing the "gatekeeper" not the "landscaper" hypothesis

1999

Journal Article

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways

Jass, J. R., Biden, K. G., Cummings, M. C., Simms, L. A., Walsh, M., Schoch, E., Metlzer, S. J., Wright, C., Searle, J., Young, J. and Leggett, B. A. (1999). Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways. Journal of Clinical Pathology, 52 (6), 455-460. doi: 10.1136/jcp.52.6.455

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways

1999

Journal Article

Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability

Biden, Kelli G., Simms, Lisa A., Cummings, Margaret, Buttenshaw, Ron, Schoch, Estelle, Searle, Jeffrey, Gobe, Glenda, Jass, Jeremy R., Meltzer, Stephen J., Leggett, Barbara A. and Young, Joanne (1999). Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability. Oncogene, 18 (5), 1245-1249. doi: 10.1038/sj.onc.1202413

Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability

1999

Journal Article

Angiogenic factor VEGF is decreased in human colorectal neoplasms showing DNA microsatellite instability

Wynter, C. V. A., Simms, L. A., Buttenshaw, R. L., Biden, K. G., Young, J., Leggett, B. A., Conrad, R. J., Schoch, E. M., Jass, J. R. and Pillay, S. P. (1999). Angiogenic factor VEGF is decreased in human colorectal neoplasms showing DNA microsatellite instability. Journal of Pathology, 189 (3), 319-325. doi: 10.1002/(SICI)1096-9896(199911)189:33.3.CO;2-U

Angiogenic factor VEGF is decreased in human colorectal neoplasms showing DNA microsatellite instability

1999

Conference Publication

Microsatellite instability occurs early in adenoma development in hereditary non-polyposis colorectal cancer and becomes more extensive with the development of high grade dysplasia

Iino, H., Young, J. P., Simms, L. A., Jass, J. R. and Leggett, B. A. (1999). Microsatellite instability occurs early in adenoma development in hereditary non-polyposis colorectal cancer and becomes more extensive with the development of high grade dysplasia. The Gastroenterological Society of Queensland, Coolum, Qld, 12 - 14 June, 1999.

Microsatellite instability occurs early in adenoma development in hereditary non-polyposis colorectal cancer and becomes more extensive with the development of high grade dysplasia

1999

Conference Publication

Early divergence of the DNA mismatch repair deficient pathway in colorectal tumorigenesis

Biden, K. G., Wright, C.M., Simms, L. A., Macdonald, G. A., Jass, J. R., Young, J. P. and Leggett, B. A. (1999). Early divergence of the DNA mismatch repair deficient pathway in colorectal tumorigenesis. From Genes to the Clinic & Beyond. Understanding & Managing Bowel Cancer, Melbourne & Lorne, 1-6 March, 1999.

Early divergence of the DNA mismatch repair deficient pathway in colorectal tumorigenesis

1999

Conference Publication

Microsatellite instability testing of tumours occurring in high-risk colorectal cancer families

Barker, M. A., Young, J. P., Webb, S. I., Buttenshaw, R. L., McKeone, D. M., Neal, J. I., Searle, J., Jass, J. R. and Leggett, B. A. (1999). Microsatellite instability testing of tumours occurring in high-risk colorectal cancer families. Australian Gastroenterology Week 1999, Brisbane, 4th - 8th October, 1999. Asia: Blackwell Science.

Microsatellite instability testing of tumours occurring in high-risk colorectal cancer families

1999

Conference Publication

Microsatellite instability occurs early in adenoma development in hereditary non-polyposis colorectal cancer and becomes more extensive with the development of high grade dysplasia

Iino, H., Biden, K. G., Young, J. P., Simms, L. A., Jass, J. R. and Leggett, B. A. (1999). Microsatellite instability occurs early in adenoma development in hereditary non-polyposis colorectal cancer and becomes more extensive with the development of high grade dysplasia. Australian Gastroenterology Week 1999, Brisbane, 4-8 Oct, 1999. Carlton, Vic: Blackwell Science.

Microsatellite instability occurs early in adenoma development in hereditary non-polyposis colorectal cancer and becomes more extensive with the development of high grade dysplasia

1999

Conference Publication

Patterns of expression of MUC1, MUC2, MUC4 and MUC5AC mucins in hyperplastic polyps, serrated adenomas and traditional adenomas of the colorectum

Biemer-Huttmann, A., Walsh, M. D., McGuckin, M. A., Ajioka, Y., Watanabe, H., Leggett, B. A. and Jass, J. R. (1999). Patterns of expression of MUC1, MUC2, MUC4 and MUC5AC mucins in hyperplastic polyps, serrated adenomas and traditional adenomas of the colorectum. Lorne, Vic., 11-14 Feb, 1999.

Patterns of expression of MUC1, MUC2, MUC4 and MUC5AC mucins in hyperplastic polyps, serrated adenomas and traditional adenomas of the colorectum

1999

Journal Article

DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?

Iino, H., Jass, J. R., Simms, L. A., Young, J., Leggett, B., Ajioka, Y. and Watanabe, H. (1999). DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?. Journal of Clinical Pathology, 52 (1), 5-9. doi: 10.1136/jcp.52.1.5

DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?

1999

Conference Publication

CASPASE-5 - A target gene for mutation in the microsatellite mutator pathway of sporadic colorectal cancers?

Whitehall, V. L., Simms, L. A., Jass, J. R., Young, J. P. and Leggett, B. A. (1999). CASPASE-5 - A target gene for mutation in the microsatellite mutator pathway of sporadic colorectal cancers?. Royal Brisbane Hospital Health Care Symposium, Westpac Auditorium Bancroft Cen., QIMR, Brisbane, 21 - 27 Oct, 1999. Brisbane: Royal Brisbane Hospital.

CASPASE-5 - A target gene for mutation in the microsatellite mutator pathway of sporadic colorectal cancers?

1999

Conference Publication

Characterization of tumour infiltrating lymphocytes in microsatellite stable and unstable colorectal carcinoma

Robinson, J., Biemer-Huettmann, A., Simms, L. A., Jass, J. R., Walsh, M. D., Young, J. P., Leggett, B. A. and Radford-Smith, G. L. (1999). Characterization of tumour infiltrating lymphocytes in microsatellite stable and unstable colorectal carcinoma. Royal Brisbane Hospital Health Care Symposium, Brisbane, 21st - 27th October, 1999.

Characterization of tumour infiltrating lymphocytes in microsatellite stable and unstable colorectal carcinoma

1999

Conference Publication

The effect of human bile and bile acids on duodenal epithelial cells

Karamatic, R., Donnan, K. D., Cummings, M. C., Winterford, C. M., Young, J. P., Leggett, B. A. and Radford-Smith, G. L. (1999). The effect of human bile and bile acids on duodenal epithelial cells. The Gastroenterological Society of Queensland, Coolum, Queensland, 12th - 14th June, 1999.

The effect of human bile and bile acids on duodenal epithelial cells

1999

Conference Publication

Improved survival in stage C colorectal cancers exhibiting microsatellite instability

Wright, C.M., Whitehall, V. L., Dent, O. F., Walsh, M. D., Searle, J., Newland, R. C., Chapuis, P. H., Jass, J. R., Young, J. P., Leggett, B. A. and Macdonald, G. (1999). Improved survival in stage C colorectal cancers exhibiting microsatellite instability. From Genes to the Clinic & Beyond. Understanding & Managing Bowel Cancer, Melbourne & Lorne, 1 - 6 March 1999.

Improved survival in stage C colorectal cancers exhibiting microsatellite instability

1999

Conference Publication

Up-regulation of P73 in hepatocellular carcinoma

Herath, N. I., Kew, M. C., Whitehall, V. L., Young, J. P., Powell, L. W., Leggett, B. A. and Macdonald, G. A. (1999). Up-regulation of P73 in hepatocellular carcinoma. Entering a New Era, Wyndham Anatole Hotel, Dallas, Texas, 5-9 November, 1999. Hoboken, NJ: Wiley Interscience.

Up-regulation of P73 in hepatocellular carcinoma

1999

Conference Publication

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator phenotypes

Jass, J. R., Cummings, M. C., Simms, L. A., Walsh, M., Schoch, E., Meltzer, S. J., Wright, C., Searle, J., Young, J. P. and Leggett, B. A. (1999). Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator phenotypes. 11th Lorne Cancer Conference, Lorne, Victoria, Australia, 11th -14th February, 1999.

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator phenotypes

1999

Conference Publication

Characterization of tumour infiltrating lymphocytes in microsatellite stable and microsatellite unstable colorectal cancer

Robinson, J., Biemer-Huttmann, A., Simms, L. A., Jass, J. R., Walsh, M. D., Young, J. P., Leggett, B. A. and Radford-Smith, G. L. (1999). Characterization of tumour infiltrating lymphocytes in microsatellite stable and microsatellite unstable colorectal cancer. Melbourne, 7-10 Nov, 1999.

Characterization of tumour infiltrating lymphocytes in microsatellite stable and microsatellite unstable colorectal cancer

1999

Conference Publication

Loss of heterozygosity at 4q in hepatocellular carcinoma is more common in patients with hepatitis B infection

Herath, N., Kew, M. C., Young, J., Powell, L. W., Leggett, B. A. and Macdonald, G. A. (1999). Loss of heterozygosity at 4q in hepatocellular carcinoma is more common in patients with hepatitis B infection. Royal Brisbane Hospital Health Care Symposium, Westpac Auditorium Bancroft Cen., QIMR, Brisbane, 21 - 27 Oct, 1999. Brisbane: Royal Brisbane Hospital.

Loss of heterozygosity at 4q in hepatocellular carcinoma is more common in patients with hepatitis B infection

Past funding

  • 2006 - 2007
    A Double-blind, randomized, placebo-controlled multi-center, Phase II parallel dose-ranging study to assess the antifibrotic activity of G1262570 in chronic hepatitis C subjects with hepatic fibrosis
    Glaxo Smith Kline Aust. Pty Ltd
    Open grant

Availability

Professor Barbara Leggett is:
Available for supervision

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Supervision history

Current supervision

  • Master Philosophy

    Yield of neoplastic lesions in a prospective Australian cohort undergoing colonoscopic surveillance in the context of high-quality colonoscopy

    Principal Advisor

Completed supervision

Enquiries

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