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Professor

Barbara Leggett

Email: 
Phone: 
+61 7 3362 0170

Overview

Availability

Professor Barbara Leggett is:
Available for supervision

Qualifications

  • Bachelor (Honours) of Medicine Surgery, The University of Queensland
  • Doctoral Diploma of Medicine, The University of Queensland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Physicians, Royal College of Physicians

Works

Search Professor Barbara Leggett’s works on UQ eSpace

178 works between 1990 and 2026

141 - 160 of 178 works

2000

Journal Article

Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis

Biemer-Huttmann, A. E., Walsh, M. D., McGuckin, M. A., Simms, L. A., Young, J., Leggett, B. A. and Jass, J. R. (2000). Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis. Clinical Cancer Research, 6 (5), 1909-1916.

Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis

2000

Conference Publication

p14-ARF and p16-INK4A - one locus, two genes frequently affected in sporadic colorectal cancer

Whitehall, V. L., Walsh, M., Jass, J. R., Young, J. P. and Leggett, B. A. (2000). p14-ARF and p16-INK4A - one locus, two genes frequently affected in sporadic colorectal cancer. Australian Gastroenterology Week 2000, Hobart, 18-21 Oct, 2000. Melbourn: Blackwell Scientific.

p14-ARF and p16-INK4A - one locus, two genes frequently affected in sporadic colorectal cancer

2000

Conference Publication

Juvenile polyposis lesions show clonal loss of SMAD4 in epithelial as well as stromal compartments, endorsing the "gatekeeper" not the "landscaper" hypothesis

Woodford-Richens, K., Williamson, J., Bevan, S., Young, J. P., Jass, J. R., Leggett, B. A., Frayling, I., Thway, Y., Hodgson, S., Kim, J., Iwama, T., Novelli, M., Sheer, D., Poulsom, R., Wright, N.A., Houlston, R. and Tomlinson, I. (2000). Juvenile polyposis lesions show clonal loss of SMAD4 in epithelial as well as stromal compartments, endorsing the "gatekeeper" not the "landscaper" hypothesis. Pathological Society of Great Britain & Ireland 181st Meeting, Nottingham, 12-14 Jul, 2000. England: John Wiley & Sons.

Juvenile polyposis lesions show clonal loss of SMAD4 in epithelial as well as stromal compartments, endorsing the "gatekeeper" not the "landscaper" hypothesis

2000

Conference Publication

The "highs" and "lows" of microsatellite instability in sporadic ACPS C colorectal cancer - improving prognostic stratification for this group of patients

Wright, C.M., Dent, O. F., Barker, M.A., Newland, R. C., Chapuis, P. H., Bokey, E. L., Young, J. P., Leggett, B. A., Jass, J. R. and Macdonald, G. (2000). The "highs" and "lows" of microsatellite instability in sporadic ACPS C colorectal cancer - improving prognostic stratification for this group of patients. Australian Gastroenterology Week 2000, Hobart, 18-21 Oct, 2000. Melbourne: Blackwell Scientific.

The "highs" and "lows" of microsatellite instability in sporadic ACPS C colorectal cancer - improving prognostic stratification for this group of patients

2000

Journal Article

DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer

Iino, H., Simms, L., Young, J. P., Arnold, J., Winship, I. M., Webb, S. I., Furlong, K. L., Leggett, B. A. and Jass, J. R. (2000). DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer. Gut, 47 (1), 37-42. doi: 10.1136/gut.47.1.37

DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer

2000

Conference Publication

Isolation of HPP1 alternatively spliced transcripts using 3'-race

Simms, L. A., Young, J. P., Biden, K. G., Karamatic, R., Jass, J. R. and Leggett, B. A. (2000). Isolation of HPP1 alternatively spliced transcripts using 3'-race. Australian Gastroenterology Week 2000, Hobart, 18-21 Oct, 2000. Melbourne: Blackwell Scientific.

Isolation of HPP1 alternatively spliced transcripts using 3'-race

2000

Conference Publication

Association of human aryl sulfotransferase (SULT1A1) R213H polymorphism with colorectal cancer

Wong, C., Liyou, N., Leggett, B. A., Johnson, A. and McManus, M. E. (2000). Association of human aryl sulfotransferase (SULT1A1) R213H polymorphism with colorectal cancer. Australasian Society of Clinical, Newcastle, Australia, December, 2000. Melbourne: Blackwell Scientific Publications.

Association of human aryl sulfotransferase (SULT1A1) R213H polymorphism with colorectal cancer

1999

Journal Article

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways

Jass, J. R., Biden, K. G., Cummings, M. C., Simms, L. A., Walsh, M., Schoch, E., Metlzer, S. J., Wright, C., Searle, J., Young, J. and Leggett, B. A. (1999). Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways. Journal of Clinical Pathology, 52 (6), 455-460. doi: 10.1136/jcp.52.6.455

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways

1999

Journal Article

Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability

Biden, Kelli G., Simms, Lisa A., Cummings, Margaret, Buttenshaw, Ron, Schoch, Estelle, Searle, Jeffrey, Gobe, Glenda, Jass, Jeremy R., Meltzer, Stephen J., Leggett, Barbara A. and Young, Joanne (1999). Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability. Oncogene, 18 (5), 1245-1249. doi: 10.1038/sj.onc.1202413

Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability

1999

Conference Publication

Patterns of expression of MUC1, MUC2, MUC4 and MUC5AC mucins in hyperplastic polyps, serrated adenomas and traditional adenomas of the colorectum

Biemer-Huttmann, A., Walsh, M. D., McGuckin, M. A., Ajioka, Y., Watanabe, H., Leggett, B. A. and Jass, J. R. (1999). Patterns of expression of MUC1, MUC2, MUC4 and MUC5AC mucins in hyperplastic polyps, serrated adenomas and traditional adenomas of the colorectum. Lorne, Vic., 11-14 Feb, 1999.

Patterns of expression of MUC1, MUC2, MUC4 and MUC5AC mucins in hyperplastic polyps, serrated adenomas and traditional adenomas of the colorectum

1999

Journal Article

DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?

Iino, H., Jass, J. R., Simms, L. A., Young, J., Leggett, B., Ajioka, Y. and Watanabe, H. (1999). DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?. Journal of Clinical Pathology, 52 (1), 5-9. doi: 10.1136/jcp.52.1.5

DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?

1999

Conference Publication

CASPASE-5 - A target gene for mutation in the microsatellite mutator pathway of sporadic colorectal cancers?

Whitehall, V. L., Simms, L. A., Jass, J. R., Young, J. P. and Leggett, B. A. (1999). CASPASE-5 - A target gene for mutation in the microsatellite mutator pathway of sporadic colorectal cancers?. Royal Brisbane Hospital Health Care Symposium, Westpac Auditorium Bancroft Cen., QIMR, Brisbane, 21 - 27 Oct, 1999. Brisbane: Royal Brisbane Hospital.

CASPASE-5 - A target gene for mutation in the microsatellite mutator pathway of sporadic colorectal cancers?

1999

Conference Publication

Characterization of tumour infiltrating lymphocytes in microsatellite stable and unstable colorectal carcinoma

Robinson, J., Biemer-Huettmann, A., Simms, L. A., Jass, J. R., Walsh, M. D., Young, J. P., Leggett, B. A. and Radford-Smith, G. L. (1999). Characterization of tumour infiltrating lymphocytes in microsatellite stable and unstable colorectal carcinoma. Royal Brisbane Hospital Health Care Symposium, Brisbane, 21st - 27th October, 1999.

Characterization of tumour infiltrating lymphocytes in microsatellite stable and unstable colorectal carcinoma

1999

Conference Publication

The effect of human bile and bile acids on duodenal epithelial cells

Karamatic, R., Donnan, K. D., Cummings, M. C., Winterford, C. M., Young, J. P., Leggett, B. A. and Radford-Smith, G. L. (1999). The effect of human bile and bile acids on duodenal epithelial cells. The Gastroenterological Society of Queensland, Coolum, Queensland, 12th - 14th June, 1999.

The effect of human bile and bile acids on duodenal epithelial cells

1999

Conference Publication

Improved survival in stage C colorectal cancers exhibiting microsatellite instability

Wright, C.M., Whitehall, V. L., Dent, O. F., Walsh, M. D., Searle, J., Newland, R. C., Chapuis, P. H., Jass, J. R., Young, J. P., Leggett, B. A. and Macdonald, G. (1999). Improved survival in stage C colorectal cancers exhibiting microsatellite instability. From Genes to the Clinic & Beyond. Understanding & Managing Bowel Cancer, Melbourne & Lorne, 1 - 6 March 1999.

Improved survival in stage C colorectal cancers exhibiting microsatellite instability

1999

Conference Publication

Up-regulation of P73 in hepatocellular carcinoma

Herath, N. I., Kew, M. C., Whitehall, V. L., Young, J. P., Powell, L. W., Leggett, B. A. and Macdonald, G. A. (1999). Up-regulation of P73 in hepatocellular carcinoma. Entering a New Era, Wyndham Anatole Hotel, Dallas, Texas, 5-9 November, 1999. Hoboken, NJ: Wiley Interscience.

Up-regulation of P73 in hepatocellular carcinoma

1999

Conference Publication

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator phenotypes

Jass, J. R., Cummings, M. C., Simms, L. A., Walsh, M., Schoch, E., Meltzer, S. J., Wright, C., Searle, J., Young, J. P. and Leggett, B. A. (1999). Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator phenotypes. 11th Lorne Cancer Conference, Lorne, Victoria, Australia, 11th -14th February, 1999.

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator phenotypes

1999

Conference Publication

Characterization of tumour infiltrating lymphocytes in microsatellite stable and microsatellite unstable colorectal cancer

Robinson, J., Biemer-Huttmann, A., Simms, L. A., Jass, J. R., Walsh, M. D., Young, J. P., Leggett, B. A. and Radford-Smith, G. L. (1999). Characterization of tumour infiltrating lymphocytes in microsatellite stable and microsatellite unstable colorectal cancer. Melbourne, 7-10 Nov, 1999.

Characterization of tumour infiltrating lymphocytes in microsatellite stable and microsatellite unstable colorectal cancer

1999

Conference Publication

Loss of heterozygosity at 4q in hepatocellular carcinoma is more common in patients with hepatitis B infection

Herath, N., Kew, M. C., Young, J., Powell, L. W., Leggett, B. A. and Macdonald, G. A. (1999). Loss of heterozygosity at 4q in hepatocellular carcinoma is more common in patients with hepatitis B infection. Royal Brisbane Hospital Health Care Symposium, Westpac Auditorium Bancroft Cen., QIMR, Brisbane, 21 - 27 Oct, 1999. Brisbane: Royal Brisbane Hospital.

Loss of heterozygosity at 4q in hepatocellular carcinoma is more common in patients with hepatitis B infection

1999

Journal Article

Ultrastructural localisation of epithelial mucin core proteins in colorectal tissue

Winterford, C. M., Walsh, M., Leggett, B. A. and Jass, J. R. (1999). Ultrastructural localisation of epithelial mucin core proteins in colorectal tissue. Journal of Histochemistry & Cytochemistry, 47 (8), 1063-1074. doi: 10.1177/002215549904700811

Ultrastructural localisation of epithelial mucin core proteins in colorectal tissue

Funding

Past funding

  • 2006 - 2007
    A Double-blind, randomized, placebo-controlled multi-center, Phase II parallel dose-ranging study to assess the antifibrotic activity of G1262570 in chronic hepatitis C subjects with hepatic fibrosis
    Glaxo Smith Kline Aust. Pty Ltd
    Open grant

Supervision

Availability

Professor Barbara Leggett is:
Available for supervision

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Supervision history

Current supervision

  • Master Philosophy

    Yield of neoplastic lesions in a prospective Australian cohort undergoing colonoscopic surveillance in the context of high-quality colonoscopy

    Principal Advisor

Completed supervision

Media

Enquiries

For media enquiries about Professor Barbara Leggett's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au