
Overview
Availability
- Dr James Daveson is:
- Available for supervision
Research interests
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Coeliac Disease
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Inflammatory Bowel Disease
Research impacts
I am an adult gastroenterologist with a specialty interest in coeliac disease (CD) and have developed expertise as a clinician-researcher in this field. My career involves undertaking investigator-led research in CD, leading as Principal Investigator (PI) several industry supported trials, including in CD, and managing a busy clinical practice including a CD clinic. My publications in the CD have been highly translational and informed clinical practice.
After completing specialty training in gastroenterology in 2008, I subsequently established a large clinical practice that now employs four gastroenterologists in Brisbane and Central Queensland with a database of > 10,000 patients. In 2014, I established the first regional inflammatory bowel disease (IBD) clinic in the Mackay-Isaac-Whitsunday region after forming a key stakeholder interest group with Mackay Hospital and Health Service and the Mater Misericordiae Hospital. This spans an area of 90,000 sq km with a population of 180,000. It is the only gastroenterology clinic servicing both the public and private sectors between the Sunshine Coast and Townsville, and now caters for a large and well-characterized population of patients with CD and Inflammatory Bowel Disease (IBD).
Works
Search Professor James Daveson’s works on UQ eSpace
Featured
2020
Journal Article
Baseline quantitative histology in therapeutics trials reveals villus atrophy in most patients with coeliac disease who appear well controlled on gluten‐free diet
Daveson, A. James M., Popp, Alina, Taavela, Juha, Goldstein, Kaela E., Isola, Jorma, Truitt, Kenneth E., Mäki, Markku, Anderson, Robert P., on behalf of the RESET CeD Study Group, Adams, A., Andrews, J., Behrend, C., Brown, G., Chen Yi Mei, S., Coates, A., Daveson, A.J., DiMarino, A., Elliott, D., Epstein, R., Feyen, B., Fogel, R., Friedenberg, K., Gearry, R., Gerdis, M., Goldstein, M., Gupta, V., Holmes, R., Holtmann, G., Idarraga, S. ... Wilson, S. (2020). Baseline quantitative histology in therapeutics trials reveals villus atrophy in most patients with coeliac disease who appear well controlled on gluten‐free diet. GastroHep, 2 (1), 22-30. doi: 10.1002/ygh2.380
Featured
2019
Journal Article
Masked bolus gluten challenge low in FODMAPs implicates nausea and vomiting as key symptoms associated with immune activation in treated coeliac disease
Daveson, A. James M., Tye-Din, Jason A., Goel, Gautam, Goldstein, Kaela E., Hand, Holly L., Neff, Kristin M., Williams, Leslie J., Truitt, Kenneth E., Anderson, Robert P., on behalf of the RESET CeD Study Group, Adams, A., Andrews, J., Behrend, C., Brown, G., Mei, S. Chen Yi, Coates, A., Daveson, A. J. M., DiMarino, A., Ee, H., Elliott, D., Epstein, R., Feyen, B., Fogel, R., Friedenberg, K., Gearry, R., Gerdis, M., Goldstein, M., Gupta, V., Holmes, R. ... Wilson, S. (2019). Masked bolus gluten challenge low in FODMAPs implicates nausea and vomiting as key symptoms associated with immune activation in treated coeliac disease. Alimentary Pharmacology & Therapeutics, 51 (2), 244-252. doi: 10.1111/apt.15551
Featured
2017
Journal Article
Epitope Specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies
Goel, Gautam, King, Tim, Daveson, A. James, Andrews, Jane M., Krishnarajah, Janakan, Krause, Richard, Brown, Gregor J. E., Fogel, Ronald, Barish, Charles F., Epstein, Roger, Kinney, Timothy P., Miner Jr, Philip B., Girardin, Adam, Tye-Din, Jason A., Girardin, Adam, Taavela, Juha, Popp, Alina, Sidney, John, Maki, Makku, Goldstein, Kaela E., Griffin, Patrick H., Wang, Suyue, Dzuris, John L., Williams, Leslie J., Sette, Alessandro, Xavier, Ramnik J., Sollid, Ludvig M., Jabri, Bana and Anderson, Robert P. (2017). Epitope Specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies. The Lancet Gastroenterology and Hepatology, 2 (7), 479-493. doi: 10.1016/S2468-1253(17)30110-3
Featured
2011
Journal Article
Effect of hookworm infection on wheat challenge in celiac disease - A randomised double-blinded placebo controlled trial
Daveson, A. James, Jones, Dianne M., Gaze, Soraya, McSorley, Henry, Clouston, Andrew, Pascoe, Andrew, Cooke, Sharon, Speare, Richard, Macdonald, Graeme A., Anderson, Robert, McCarthy, James S., Loukas, Alex and Croese, John (2011). Effect of hookworm infection on wheat challenge in celiac disease - A randomised double-blinded placebo controlled trial. PLoS One, 6 (3, Article number e17366) e17366, e17366-1-e17366-9. doi: 10.1371/journal.pone.0017366
2025
Journal Article
Safety, clinical activity, pharmacodynamics, and pharmacokinetics of IMU-856, a SIRT6 modulator, in coeliac disease: a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial
Daveson, A. James M., Stubbs, Richard, Polasek, Thomas M., Isola, Jorma, Anderson, Robert, Tye-Din, Jason A., Schoeman, Mark, Lionnet, Claudette, Mei, Swee Lin Chen Yi, Mihajlović, Jelena, Wirth, Martina, Peelen, Evelyn, Schreieck, Amelie, Kohlhof, Hella, Vitt, Daniel, Muehler, Andreas and Buriánek, Franziska (2025). Safety, clinical activity, pharmacodynamics, and pharmacokinetics of IMU-856, a SIRT6 modulator, in coeliac disease: a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial. The Lancet Gastroenterology and Hepatology, 10 (1), 44-54. doi: 10.1016/s2468-1253(24)00248-6
2024
Journal Article
Splenic artery collateral masquerading as a gastric varix post splenic trauma
Daveson, A.J.M., O’Rourke, T. and Davis, S. (2024). Splenic artery collateral masquerading as a gastric varix post splenic trauma. Gastrointestinal Endoscopy, 99 (1), 120-121. doi: 10.1016/j.gie.2023.07.004
2023
Journal Article
Undiagnosed coeliac disease identified by active case finding in first degree relatives of people with coeliac disease in Australia: a prospective observational study
Muir, Richard, Sehgal, Anuj, Tye‐Din, Jason A and Daveson, A James M (2023). Undiagnosed coeliac disease identified by active case finding in first degree relatives of people with coeliac disease in Australia: a prospective observational study. Medical Journal of Australia, 219 (8), 371-373. doi: 10.5694/mja2.52105
2023
Journal Article
High incidence of inflammatory bowel disease in Northern Australia: a prospective community population‐based Australian incidence study in the Mackay‐Isaac‐Whitsunday region
Flanagan, Amanda, Allsopp, Susan M., O'Connor, Sam A., Tobin, Jacinta, Pretorius, Casper, Brown, Ian S., Bell, Sally and Daveson, A. James M. (2023). High incidence of inflammatory bowel disease in Northern Australia: a prospective community population‐based Australian incidence study in the Mackay‐Isaac‐Whitsunday region. Internal Medicine Journal, 53 (9), 1602-1609. doi: 10.1111/imj.15941
2023
Journal Article
Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study
Tye-Din, Jason A, Daveson, A James M, Goel, Gautam, Goldstein, Kaela E, Hand, Holly L, Neff, Kristin M, Popp, Alina, Taavela, Juha, Maki, Markku, Isola, Jorma, Williams, Leslie J, Truitt, Kenneth E, Anderson, Robert P, Adams, Atoya, Andrews, Jane M, Behrend, Clint E, Brown, Gregor J E, Chen Yi Mei, Swee Lin, Coates, Allan G, DiMarino, Anthony J, Ee, Hooi, Elliott, David E, Epstein, Roger M, Feyen, Bryan John, Fogel, Ronald P, Friedenberg, Keith Alan, Gearry, Richard B, Gerdis, Michael S, Goldstein, Michael J ... Wilson, Scott A (2023). Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study. The Lancet Gastroenterology and Hepatology, 8 (5), 446-457. doi: 10.1016/s2468-1253(22)00428-9
2023
Conference Publication
High incidence of inflammatory bowel disease in Northern Australia: a prospective community population-based Australian incidence study in the Mackay-Isaac-Whitsunday region
Flanagan, A., O'Connor, S., Allsop, S., Tobin, J., Pretorius, C., Brown, I., Bell, S. and Daveson, A. J. (2023). High incidence of inflammatory bowel disease in Northern Australia: a prospective community population-based Australian incidence study in the Mackay-Isaac-Whitsunday region. OXFORD: OXFORD UNIV PRESS.
2023
Conference Publication
High incidence of inflammatory bowel disease in Northern Australia: a prospective community population-based Australian incidence study in the Mackay-Isaac-Whitsunday region
Flanagan, A., O'Connor, S., Allsop, S., Tobin, J., Pretorius, C., Brown, I., Bell, S. and Daveson, A. J. (2023). High incidence of inflammatory bowel disease in Northern Australia: a prospective community population-based Australian incidence study in the Mackay-Isaac-Whitsunday region. 18th Congress of ECCO, Copenhagen, Denmark, 1-4 March 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjac190.1010
2022
Journal Article
Tattoo sarcoidosis presenting as abdominal allodynia
Faint, Annabelle and Daveson, A. James M. (2022). Tattoo sarcoidosis presenting as abdominal allodynia. Medical Journal of Australia, 217 (1), 23-23. doi: 10.5694/mja2.51603
2020
Journal Article
Patient factors influencing acute gluten reactions and cytokine release in treated coeliac disease
Tye-Din, Jason A., Daveson, A. James M., Goldstein, Kaela E., Hand, Holly L., Neff, Kristin M., Goel, Gautam, Williams, Leslie J., Truitt, Kenneth E., Anderson, Robert P., RESET CeD Study Group and Holtmann, G. (2020). Patient factors influencing acute gluten reactions and cytokine release in treated coeliac disease. BMC medicine, 18 (1) 362, 362. doi: 10.1186/s12916-020-01828-y
2020
Journal Article
Editorial: inaccuracies in attribution of symptoms due to gluten—not just in those with self-reported noncoeliac gluten sensitivity. Authors' reply
Daveson, A. James M., Tye-Din, Jason A. and Anderson, Robert P. (2020). Editorial: inaccuracies in attribution of symptoms due to gluten—not just in those with self-reported noncoeliac gluten sensitivity. Authors' reply. Alimentary Pharmacology and Therapeutics, 51 (3), 403-404. doi: 10.1111/apt.15629
2019
Journal Article
Serum cytokines elevated during gluten-mediated cytokine release in coeliac disease
Goel, G., Daveson, A. J. M., Hooi, C. E., Tye-Din, J. A., Wang, S., Szymczak, E., Williams, L. J., Dzuris, J. L., Neff, K. M., Truitt, K. E. and Anderson, R. P. (2019). Serum cytokines elevated during gluten-mediated cytokine release in coeliac disease. Clinical and Experimental Immunology, 199 (1) cei.13369, 68-78. doi: 10.1111/cei.13369
2019
Journal Article
Elevated serum interleukin-2 after gluten correlates with symptoms and is a potential diagnostic biomarker for coeliac disease
Tye-Din, Jason A., Daveson, A. James M., Ee, Hooi C., Goel, Gautam, MacDougall, James, Acaster, Sarah, Goldstein, Kaela E., Dzuris, John L., Neff, Kristin M., Truitt, Kenneth E. and Anderson, Robert P. (2019). Elevated serum interleukin-2 after gluten correlates with symptoms and is a potential diagnostic biomarker for coeliac disease. Alimentary Pharmacology and Therapeutics, 50 (8), 901-910. doi: 10.1111/apt.15477
2019
Journal Article
Randomised clinical trial: a placebo-controlled study of subcutaneous or intradermal NEXVAX2, an investigational immunomodulatory peptide therapy for coeliac disease
Truitt, Kenneth E., Daveson, A. James M., Ee, Hooi C., Goel, Gautam, MacDougall, James, Neff, Kristin and Anderson, Robert P. (2019). Randomised clinical trial: a placebo-controlled study of subcutaneous or intradermal NEXVAX2, an investigational immunomodulatory peptide therapy for coeliac disease. Alimentary Pharmacology & Therapeutics, 50 (5), 547-555. doi: 10.1111/apt.15435
2018
Journal Article
High rates of variation in HLA-DQ2/DQ8 testing for coeliac disease: results from an RCPAQAP pilot program
Horan, Martin Patrick, Chai, Sze Yee, Munusamy, Nalishia, Tay, Kwang Hong, Wienholt, Louise, Tye-Din, Jason A, Daveson, James, Varney, Michael and Badrick, Tony (2018). High rates of variation in HLA-DQ2/DQ8 testing for coeliac disease: results from an RCPAQAP pilot program. Journal of Clinical Pathology, 71 (10), jclinpath-2018. doi: 10.1136/jclinpath-2018-205209
2017
Journal Article
Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study
Daveson, A. James M., Ee, Hooi C., Andrews, Jane M., King, Timothy, Goldstein, Kaela E., Dzuris, John L., MacDougall, James A., Williams, Leslie J., Treohan, Anita, Cooreman, Michael P. and Anderson, Robert P. (2017). Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study. EBioMedicine, 26, 78-90. doi: 10.1016/j.ebiom.2017.11.018
2017
Journal Article
Discrepancies in genetic testing results for coeliac disease: call for standardised testing and reporting
Daveson, A. James M. , Varney, Michael, Jackson, Kate E. and Tye-Din, Jason A. (2017). Discrepancies in genetic testing results for coeliac disease: call for standardised testing and reporting. Medical Journal Australia, 207 (4), 179-180. doi: 10.5694/mja17.00314
Supervision
Availability
- Dr James Daveson is:
- Available for supervision
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