Dr Huy Hoang
Dr

Huy Hoang

Email: 
Phone: 
+61 7 334 62988

Background

Organic Chemistry

PhD

Availability

Dr Huy Hoang is:
Available for supervision

Fields of research

Inorganic chemistry Medicinal and biomolecular chemistry

Qualifications

  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Search Professor Huy Hoang’s works on UQ eSpace

71 works between 1999 and 2024
All (71) Journal Article (49) Book Chapter (1) Conference Publication (19) Other Outputs (2)

21 - 40 of 71 works

2015

Journal Article

Flexibility versus rigidity for orally bioavailable cyclic hexapeptides

Nielsen, Daniel S., Lohman, Rink-Jan, Hoang, Huy Ngoc, Hill, Timothy A., Jones, Alun, Lucke, Andrew J. and Fairlie, David P. (2015). Flexibility versus rigidity for orally bioavailable cyclic hexapeptides. Chembiochem, 16 (16), 2289-2293. doi: 10.1002/cbic.201500441

Flexibility versus rigidity for orally bioavailable cyclic hexapeptides

2015

Journal Article

Short hydrophobic peptides with cyclic constraints are potent glucagon-like peptide-1 receptor (GLP-1R) agonists

Hoang, Huy N., Song, Kun, Hill, Timothy A., Derksen, David R., Edmonds, David J., Kok, W. Mei, Limberakis, Chris, Liras, Spiros, Loria, Paula M., Mascitti, Vincent, Mathiowetz, Alan M., Mitchell, Justin M., Piotrowski, David W., Price, David A., Stanton, Robert V., Suen, Jacky Y., Withka, Jane M., Griffith, David A. and Fairlie, David P. (2015). Short hydrophobic peptides with cyclic constraints are potent glucagon-like peptide-1 receptor (GLP-1R) agonists. Journal of Medicinal Chemistry, 58 (9), 4080-4085. doi: 10.1021/acs.jmedchem.5b00166

Short hydrophobic peptides with cyclic constraints are potent glucagon-like peptide-1 receptor (GLP-1R) agonists

2015

Journal Article

Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids

Lindahl, Fredrik, Hoang, Huy N., Fairlie, David P. and Cooper, Matthew A. (2015). Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids. Chemical Communications, 51 (21), 4496-4498. doi: 10.1039/c4cc09780g

Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids

2015

Book Chapter

Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception

Lohman, Rink-Jan, Harrison, Rosemary S., Ruiz-Gomez, Gloria, Hoang, Huy Ngoc, Shepherd, Nicholas E., Chow, Shiao, Hill, Timothy A., Madala, Praveen K. and Fairlie, David P. (2015). Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception. Nociceptin opioid. (pp. 1-55) edited by Gerald Litwack. Maryland Heights, MO, United States: Academic Press. doi: 10.1016/bs.vh.2014.10.001

Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception

2015

Conference Publication

Cyclic penta- and hexa leucine peptides without N-methylation are orally absorbed

Kok, Woan Mei, Hill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor G., Schroeder, Christina I., Colless, Barbara, Bernhardt, Paul V., Edmonds, David, Griffith, David, Rotter, Charles, Ruggeri, Roger, Price, David, Liras, Spiros, Craik, David and Fairlie, David (2015). Cyclic penta- and hexa leucine peptides without N-methylation are orally absorbed. American Chemical Society Meeting, x, 2015. Washington, DC United States: American Chemical Society.

Cyclic penta- and hexa leucine peptides without N-methylation are orally absorbed

2015

Other Outputs

Reactivity of commercially available Fmoc amino acids: supplementary information

Lindahl, Fredrik, Hoang, Huy Ngoc, Fairlie, David P. and Cooper, Matthew A. (2015). Reactivity of commercially available Fmoc amino acids: supplementary information. The Royal Society of Chemistry. (Dataset)

Reactivity of commercially available Fmoc amino acids: supplementary information

2014

Journal Article

Improving on nature: making a cyclic heptapeptide orally bioavailable

Nielsen, Daniel S., Hoang, Huy N., Lohman, Rink-Jan, Hill, Timothy A., Lucke, Andrew J., Craik, David J., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros and Fairlie, David P. (2014). Improving on nature: making a cyclic heptapeptide orally bioavailable. Angewandte Chemie - International Edition, 53 (45), 12059-12063. doi: 10.1002/anie.201405364

Improving on nature: making a cyclic heptapeptide orally bioavailable

2014

Journal Article

Helical cyclic pentapeptides constrain HIV-1 Rev peptide for enhanced RNA binding

Harrison, Rosemary S., Shepherd, Nicholas E., Hoang, Huy N., Beyer, Renee L., Ruiz-Gomez, Gloria, Kelso, Michael J., Mei Kok, W., Hill, Timothy A., Abbenante, Giovanni and Fairlie, David P. (2014). Helical cyclic pentapeptides constrain HIV-1 Rev peptide for enhanced RNA binding. Tetrahedron, 70 (42), 7645-7650. doi: 10.1016/j.tet.2014.07.096

Helical cyclic pentapeptides constrain HIV-1 Rev peptide for enhanced RNA binding

2014

Journal Article

Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed

Hill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor C. G., Kok, W. Mei, Liu, Ligong, Lucke, Andrew J., Stoermer, Martin J., Schroeder, Christina I., Chaousis, Stephanie, Colless, Barbara, Bernhardt, Paul V., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros, Craik, David J. and Fairlie, David P. (2014). Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed. ACS Medicinal Chemistry Letters, 5 (10), 1148-1151. doi: 10.1021/ml5002823

Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed

2014

Journal Article

Comparative α-Helicity of Cyclic Pentapeptides in Water

de Araujo, Aline D., Hoang, Huy N., Kok, W. Mei, Diness, Frederik, Gupta, Praveer, Hill, Timothy A., Driver, Russell W., Price, David A., Liras, Spiros and Fairlie, David P. (2014). Comparative α-Helicity of Cyclic Pentapeptides in Water. Angewandte Chemie International Edition, 53 (27), 6965-6969. doi: 10.1002/anie.201310245/abstract

Comparative α-Helicity of Cyclic Pentapeptides in Water

2013

Journal Article

Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1

Rao, Tara, Ruiz-Gomez, Gloria, Hill, Timothy A., Hoang, Huy N., Fairlie, David P. and Mason, Jody M. (2013). Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1. PLoS One, 8 (3) e59415, e59415.1-e59415.12. doi: 10.1371/journal.pone.0059415

Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1

2013

Journal Article

Total synthesis, structure, and oral absorption of a thiazole cyclic peptide, sanguinamide A

Nielsen, Daniel S., Hoang, Huy N., Lohman, Rink-Jan, Diness, Frederik and Fairlie, David P. (2013). Total synthesis, structure, and oral absorption of a thiazole cyclic peptide, sanguinamide A. Organic Letters, 14 (22), 5720-5723. doi: 10.1021/ol3027347

Total synthesis, structure, and oral absorption of a thiazole cyclic peptide, sanguinamide A

2012

Journal Article

Folding pentapeptides into left and right handed alpha helices

Hoang, Huy N., Abbenante, Giovanni, Hill, Timothy A., Ruiz-Gomez, Gloria and Fairlie, David P. (2012). Folding pentapeptides into left and right handed alpha helices. Tetrahedron, 68 (23), 4513-4516. doi: 10.1016/j.tet.2011.10.108

Folding pentapeptides into left and right handed alpha helices

2011

Journal Article

Protein a-turns recreated in structurally stable small molecules

Hoang, Huy N., Driver, Russell W., Beyer, Renée L., Malde, Alpeshkumar K., Le, Giang T., Abbenante, Giovanni, Mark, Alan E. and Fairlie, David P. (2011). Protein a-turns recreated in structurally stable small molecules. Angewandte Chemie International Edition, 123 (47), 11303-11307. doi: 10.1002/ange.201105119

Protein a-turns recreated in structurally stable small molecules

2011

Journal Article

Amyloid formation from an α-helical peptide bundle is seeded by 310-helix aggregates

Singh, Yogendra, Sharpe, Philip C., Hoang, Huy N., Lucke, Andrew J., McDowall, Alasdair W., Bottomley, Stephen P. and Fairlie, David P. (2011). Amyloid formation from an α-helical peptide bundle is seeded by 310-helix aggregates. Chemistry: A European Journal, 17 (1), 151-160. doi: 10.1002/chem.201002500

Amyloid formation from an α-helical peptide bundle is seeded by 310-helix aggregates

2010

Journal Article

Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice

Harrison, Rosemary S., Ruiz-Gomez, Gloria, Hill, Timothy A., Chow, Shiao Y., Shepherd, Nicholas E., Lohman, Rink-Jan, Abbenante, Giovanni, Hoang, Huy N. and Fairlie, David P. (2010). Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice. Journal of Medicinal Chemistry, 53 (23), 8400-8408. doi: 10.1021/jm101139f

Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice

2010

Journal Article

Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor (Journal of Medicinal Chemistry (2010) 53 (4938)

Scully, Conor C. G., Blakeney, Jade S., Singh, Ranee, Hoang, Huy N., Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2010). Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor (Journal of Medicinal Chemistry (2010) 53 (4938). Journal of Medicinal Chemistry, 53 (22), 8208-8208. doi: 10.1021/jm1013314

Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor (Journal of Medicinal Chemistry (2010) 53 (4938)

2010

Journal Article

Selective hexapeptide agonists and antagonists for human complement C3a receptor

Scully, Conor C. G., Blakeney, Jade S., Singh, Ranee, Hoang, Huy N., Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2010). Selective hexapeptide agonists and antagonists for human complement C3a receptor. Journal of Medicinal Chemistry, 53 (13), 4938-4948. doi: 10.1021/jm1003705

Selective hexapeptide agonists and antagonists for human complement C3a receptor

2010

Journal Article

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

Harrison, Rosemary S., Shepherd, Nicholas E., Hoang, Huy N., Ruiz-Goméz, Gloria, Hill, Timothy A., Driver, Russell W., Desai, Vishal S., Young, Paul R., Abbenante, Giovanni and Fairlie, David P. (2010). Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency. Proceedings of the National Academy of Sciences of the United States of America, 107 (26), 11686-11691. doi: 10.1073/pnas.1002498107

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

2009

Journal Article

Left- and right-handed alpha-helical turns in homo- and hetero-chiral helical scaffolds

Shepherd, N. E., Hoang, H. N., Abbenante, G and Fairlie, D. P. (2009). Left- and right-handed alpha-helical turns in homo- and hetero-chiral helical scaffolds. Journal of the American Chemical Society, 131 (43), 15877-15886. doi: 10.1021/ja9065283

Left- and right-handed alpha-helical turns in homo- and hetero-chiral helical scaffolds

Past funding

  • 2011
    Peptide Drug Synthesis and Purification Unit
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Combinatorial chemistry (high throughput synthesizer and purification system)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2007 - 2008
    Mimicking a single x-helix turn of proteins for development of novel medicines and biological probes.
    UQ Early Career Researcher
    Open grant

Availability

Dr Huy Hoang is:
Available for supervision

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Supervision history

Completed supervision

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