Overview
Background
David graduated from the University of London with a BSc (Hons) in biochemistry (King’s College) and PhD which investigated the role of epidermal growth factor receptors in liver regeneration (Imperial College). Since then he has worked on a variety of projects including; immunoassay development (Ortho Clinical Diagnostics); artificial liver machine development (Imperial College); and p53 mutations in liver cancer (QIMR). He joined the Department of Nephrology at the Princess Alexandra Hospital in Brisbane in 1999. He is a senior lecturer in The University of Queensland Faculty of Medicine, a senior member of the UQ Kidney Disease Research Laboratory and manages the Princess Alexandra Hospital Endotoxin Testing Service.
His main research interests are in the area of renal tubulointerstitial fibrosis, inflammation and also the mechanisms of renal cancer development – particularly the role that cytokines and growth factors play in these processes. Current projects include the role of protease activated receptor-2 in renal scarring, inflammation and cancer, the mechanism of heavy metal toxicity in the kidney and the renoprotective properties of erythropoietin. The Princess Alexandra Hospital Endotoxin Testing Service routinely tests samples from dialysis units throughout Queensland.
Availability
- Associate Professor David Vesey is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Biochemistry, King's College London
- Doctor of Philosophy of Gastroenterology and Hepatology, Imperial College London
Works
Search Professor David Vesey’s works on UQ eSpace
2004
Conference Publication
Silibinin inhibits renal cell carcinoma cell growth via an insulin-like growth factor (IGFBP-3) independent pathway
Cheung, C. W., Vesey, D. A., Nicol, D. L. and Johnson, D. W. (2004). Silibinin inhibits renal cell carcinoma cell growth via an insulin-like growth factor (IGFBP-3) independent pathway. 40th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Adelaide Convention Centre, Adelaide, Australia, 1–3 September, 2004. Carlton, Vic. Australia: Blackwell Science. doi: 10.1111/j.1440-1797.2004.00264.x
2004
Conference Publication
Chemotherapy induced apoptosis in renal carcinomas versus normal renal tubular epithelium: Role of PKCs
Li, J., Pat, B., Yang, T., Vesey, D., Johnson, D. W. and Gobe, G. C. (2004). Chemotherapy induced apoptosis in renal carcinomas versus normal renal tubular epithelium: Role of PKCs. 40th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Adelaide Convention Centre, Adelaide, Australia, 1–3 September, 2004. Carlton, Vic. Australia: Blackwell Science. doi: 10.1111/j.1440-1797.2004.00264.x
2004
Conference Publication
Par-2 activation mediates pro-inflammatory and proliferative responses in renal proximal tubule cells
Vesey, D. A., Cheung, C. W., Kruger, W., Poronnik, P., Gobé, G. C. and Johnson, D. W. (2004). Par-2 activation mediates pro-inflammatory and proliferative responses in renal proximal tubule cells. 40th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Adelaide Convention Centre, Adelaide, Australia, 1–3 September, 2004. Carlton, Vic. Australia: Blackwell Science. doi: 10.1111/j.1440-1797.2004.00264.x
2003
Conference Publication
Activation of protease-activated receptors (PAR) on cultured human proximal tubular cells (PAR) mediates inflammatory and fibroproliferative responses
Vesey, D. A., Cheung, C. W., Gobe, G. C. and Johnson, D. W. (2003). Activation of protease-activated receptors (PAR) on cultured human proximal tubular cells (PAR) mediates inflammatory and fibroproliferative responses. 39th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, W. A., 31 August- 3 September, 2003. Carlton South, Australia: Blackwell Publishing Asia. doi: 10.1046/j.1440-1797.8.s3.1.x
2003
Conference Publication
Renal cell carcinoma growth is regulated by autocrine insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) action
Cheung, Catherine, Vesey, David, Nicol, David and Johnson, David (2003). Renal cell carcinoma growth is regulated by autocrine insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) action. The World Congress of Nephrology, Berlin, Germany, 8-12 June, 2003. Oxford, England: Oxford University Press.
2003
Conference Publication
Thrombin stimulates pro-inflammatory and fibro-proliferative response in cultured human proximal tubule cells
Vesey, D. A., Cheung, C., Gobe, G. and Johnson, D. W. (2003). Thrombin stimulates pro-inflammatory and fibro-proliferative response in cultured human proximal tubule cells. Annual Queensland Health and Medical Scientific Meeting, Brisbane, Qld, Australia, 25-26 November, 2003. Brisbane, Qld, Australia: Queensland Health.
2003
Conference Publication
Thrombin stimulates inflammatory and fibro-proliferative responses in cultured human proximal tubule cells
Vesey, D. A., Cheung, C. W., Gobe, G. C. and Johnson, D. W. (2003). Thrombin stimulates inflammatory and fibro-proliferative responses in cultured human proximal tubule cells. 39th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, W. A., 31 August- 3 September, 2003. Carlton South, Australia: Blackwell Publishing Asia. doi: 10.1046/j.1440-1797.8.s3.1.x
2003
Conference Publication
Renal cell carcinoma growth is regulated by autocrine insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) action
Cheung, C. W., Vesey, D. A., Nicol, D. L. and Johnson, D. W. (2003). Renal cell carcinoma growth is regulated by autocrine insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) action. 39th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, Australia, 31 August - 3 September 2003. Carlton South, Australia: Blackwell Publishing Asia. doi: 10.1046/j.1440-1797.8.s3.1.x
2003
Conference Publication
Role of PKC-a and -e in cytotoxic chemotherapy of renal cell carcinomas
Li, J., Pat, B., Yan, J., Vesey, D. A., Johnson, D. W., Nicol, D. and Gobe, G. C. (2003). Role of PKC-a and -e in cytotoxic chemotherapy of renal cell carcinomas. 39th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA, Australia, 31 August- 3 September, 2003. Carlton South, Australia: Blackwell Publishing Asia. doi: 10.1046/j.1440-1797.8.s3.1.x
2002
Journal Article
Interleukin-1 beta stimulates human renal fibroblast proliferation and matrix protein production by means of a transforming growth factor-beta-dependent mechanism
Vesey, David A., Cheung, Catherine, Cuttle, Leila, Endre, Zoltan, Gobe, Glenda and Johnson, David W. (2002). Interleukin-1 beta stimulates human renal fibroblast proliferation and matrix protein production by means of a transforming growth factor-beta-dependent mechanism. Journal of Laboratory And Clinical Medicine, 140 (5), 342-350. doi: 10.1067/mlc.2002.128468
2002
Journal Article
Interleukin-1 beta induces human proximal tubule cell injury, alpha-smooth muscle actin expression and fibronectin production
Vesey, D. A., Cheung, C. W. Y., Cuttle, L., Endre, Z. A., Gobe, G. and Johnson, D. W. (2002). Interleukin-1 beta induces human proximal tubule cell injury, alpha-smooth muscle actin expression and fibronectin production. Kidney International, 62 (1), 31-40. doi: 10.1046/j.1523-1755.2002.00401.x
2002
Conference Publication
Insulin-like growth factor (IGF)-I stimulates in vitro human renal cell carcinoma (RCC) growth
Cheung, C., Vesey, D. A., Gobe, G., Nicol, D. L. and Johnson, D. W. (2002). Insulin-like growth factor (IGF)-I stimulates in vitro human renal cell carcinoma (RCC) growth. Australian and New Zealand Society of Nephrology 37th Annual Scientific Meeting, Darwin, Australia, 5-7 September, 2001. Carlton, Vic.: Blackwell Science. doi: 10.1046/j.1440-1797.2002.00007-1-15.x
2002
Journal Article
Angiotensin converting enzyme inhibitors protect against renal injury via direct effects on the tubulointerstitium: evidence from cell cultures
Johnson, D. W. and Vesey, D. A. (2002). Angiotensin converting enzyme inhibitors protect against renal injury via direct effects on the tubulointerstitium: evidence from cell cultures. Health Science, 11 (3), 14-15.
2001
Journal Article
Human adipose tissue endothelial cells promote preadipocyte proliferation
Hutley, L. J., Herington, A. C., Shurety, W., Cheung, C., Vesey, D. A., Cameron, D. P. and Prins, J. B. (2001). Human adipose tissue endothelial cells promote preadipocyte proliferation. American Journal of Physiology - Endocrinology and Metabolism, 281 (5), E1037-E1044. doi: 10.1152/ajpendo.2001.281.5.E1037
2001
Conference Publication
Interleukin-1B (IL-1B) stimulates human renal cortical fibroblast (CF) DNA synthesis and extracellular matrix production through a transforming growth factor-beta (TGFB) dependent mechanism
Vesey, D. A., Cheung, C., Gobe, G., Endre, Z. and Johnson, D. W. (2001). Interleukin-1B (IL-1B) stimulates human renal cortical fibroblast (CF) DNA synthesis and extracellular matrix production through a transforming growth factor-beta (TGFB) dependent mechanism. 37th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Darwin, NT, 5th - 7th September, 2001. Carlton, VIC: Blackwell Science. doi: 10.1046/j.1440-1797.2002.00007-1-140.x
2001
Journal Article
Inhibition of proliferation of HT-29 colon adenocarcinorna cells by carboxylate NSAIDs and their acyl glucuronides
Cannell, G. R., Vesey, D. A. and Dickinson, R. G. (2001). Inhibition of proliferation of HT-29 colon adenocarcinorna cells by carboxylate NSAIDs and their acyl glucuronides. Life Sciences, 70 (1), 37-48. doi: 10.1016/S0024-3205(01)01370-4
2000
Conference Publication
Cyclosporin (CyA) promotes human renal cortical fibroblast (CF) toxicity, extracellular matrix deposition and nitric oxide (NO) release
Vesey, D. A., Cheung, C., Endre, Z. H., Gobe, G. C. and Johnson, D. W. (2000). Cyclosporin (CyA) promotes human renal cortical fibroblast (CF) toxicity, extracellular matrix deposition and nitric oxide (NO) release. ANZSN Annual Scientific Meeting, Melbourne, 15-17 Mar, 2000.
2000
Journal Article
Enalaprilat directly ameliorates in vitro cyclosporin nephrotoxicity in human tubulo-interstitial cells
Johnson, D. W., Saunders, H. J., Vesey, D. A., Qi, W., Field, M. J. and Pollock, C. A. (2000). Enalaprilat directly ameliorates in vitro cyclosporin nephrotoxicity in human tubulo-interstitial cells. Nephron, 86 (4), 473-481. doi: 10.1159/000045837
2000
Journal Article
Peritoneal homocysteine clearance is inefficient in peritoneal dialysis patients
Johnson, David W., Kay, Troy D., Vesey, David A., Isbel, Nicole, Campbell, Scott B. and Hawley, Carmel M. (2000). Peritoneal homocysteine clearance is inefficient in peritoneal dialysis patients. Peritoneal Dialysis International, 20 (6), 766-771.
2000
Conference Publication
Interleukin-1b (IL-1b)
Vesey, D. A., Cheung, C., Endre, Z. H., Gobe, G. C. and Johnson, D. W. (2000). Interleukin-1b (IL-1b). ANZSN Annual Scientific Meeting, Melbourne, Vic, 15-17 Mar, 2000. Sydney: Australian & New Zealand Society of Nephrology.
Funding
Past funding
Supervision
Availability
- Associate Professor David Vesey is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Exploring magnetic resonance for differentiating between progressive and non-progressive chronic kidney disease
Associate Advisor
Other advisors: Professor Graham Galloway, Associate Professor Ross Francis, Dr Robert Ellis
Completed supervision
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2021
Doctor Philosophy
Clinical Biobanking and the Distinguishing Risk of Progressive Chronic Kidney Disease Study
Associate Advisor
-
2020
Doctor Philosophy
The role of the adipose tissue microenvironment in kidney cancer
Associate Advisor
Other advisors: Professor David Johnson, Dr Sumaira Hasnain
-
2020
Doctor Philosophy
Exploring Resistance of Renal Cell Carcinoma to Sunitinib Therapy
Associate Advisor
-
2016
Doctor Philosophy
Bioactive compounds from Australian Blacklip Abalone (Haliotis rubra) processing waste
Associate Advisor
-
2009
Doctor Philosophy
Targeting genes for identification and treatment of renal cell carcinoma
Associate Advisor
Other advisors: Professor David Johnson
Media
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