Overview
Background
David graduated from the University of London with a BSc (Hons) in biochemistry (King’s College) and PhD which investigated the role of epidermal growth factor receptors in liver regeneration (Imperial College). Since then he has worked on a variety of projects including; immunoassay development (Ortho Clinical Diagnostics); artificial liver machine development (Imperial College); and p53 mutations in liver cancer (QIMR). He joined the Department of Nephrology at the Princess Alexandra Hospital in Brisbane in 1999. He is a senior lecturer in The University of Queensland Faculty of Medicine, a senior member of the UQ Kidney Disease Research Laboratory and manages the Princess Alexandra Hospital Endotoxin Testing Service.
His main research interests are in the area of renal tubulointerstitial fibrosis, inflammation and also the mechanisms of renal cancer development – particularly the role that cytokines and growth factors play in these processes. Current projects include the role of protease activated receptor-2 in renal scarring, inflammation and cancer, the mechanism of heavy metal toxicity in the kidney and the renoprotective properties of erythropoietin. The Princess Alexandra Hospital Endotoxin Testing Service routinely tests samples from dialysis units throughout Queensland.
Availability
- Associate Professor David Vesey is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Biochemistry, King's College London
- Doctor of Philosophy of Gastroenterology and Hepatology, Imperial College London
Works
Search Professor David Vesey’s works on UQ eSpace
2015
Journal Article
Baseline Serum Interleukin-6 Predicts Cardiovascular Events in Incident Peritoneal Dialysis Patients
Cho, Yeoungjee, Johnson, David W., Vesey, David A., Hawley, Carmel M., Pascoe, Elaine M., Clarke, Margaret and Topley, Nicholas (2015). Baseline Serum Interleukin-6 Predicts Cardiovascular Events in Incident Peritoneal Dialysis Patients. Peritoneal Dialysis International, 35 (1), 35-42. doi: 10.3747/pdi.2013.00272
2015
Conference Publication
Indoxyl sulphate induces hypertrophy and impaired metabolic activity in cultured human proximal tubular cells
Ellis, R. J., Small, D. M., Ng, K. L., Vesey, D. A., Vitetta, L., Francis, R., Morais, C. and Gobe, G. C. (2015). Indoxyl sulphate induces hypertrophy and impaired metabolic activity in cultured human proximal tubular cells. 51st Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Canberra, Australia, 7-9 September 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12543
2015
Conference Publication
Small intestinal permeability is elevated in chronic viral hepatitis prior to the development of cirrhosis, and is associated with the degree of fibrosis
Raj, A. S., Holtmann, G., Fletcher, L., Bhat, P., Tran, C., Black, M., Nath, K., Jao, W., Vesey, D. and Macdonald, G. A. (2015). Small intestinal permeability is elevated in chronic viral hepatitis prior to the development of cirrhosis, and is associated with the degree of fibrosis. 50th International Liver Congress of the European Association for the Study of the Liver, Vienna, Austria, 22-26 April, 2015. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/S0168-8278(15)30748-0
2014
Journal Article
Pathway-selective antagonism of proteinase activated receptor 2
Suen, J. Y., Cotterell, A., Lohman, R. J., Lim, J., Han, A., Yau, M. K., Liu, L., Cooper, M. A., Vesey, D. A. and Fairlie, D. P. (2014). Pathway-selective antagonism of proteinase activated receptor 2. British Journal of Pharmacology, 171 (17), 4112-4124. doi: 10.1111/bph.12757
2014
Journal Article
Thimerosal induces apoptotic and fibrotic changes to kidney epithelial cells in vitro
Hornos Carneiro, Maria Fernanda, Morais, Christudas, Small, David M., Vesey, David A., Barbosa Jr, Fernando and Gobe, Glenda C. (2014). Thimerosal induces apoptotic and fibrotic changes to kidney epithelial cells in vitro. Environmental Toxicology, 30 (12), 1423-1433. doi: 10.1002/tox.22012
2014
Journal Article
Increased progression to kidney fibrosis after erythropoietin is used as a treatment for acute kidney injury
Gobe, Glenda C., Bennett, Nigel C., West, Malcolm, Colditz, Paul, Brown, Lindsay, Vesey, David A. and Johnson, David W. (2014). Increased progression to kidney fibrosis after erythropoietin is used as a treatment for acute kidney injury. American Journal of Physiology-Renal Physiology, 306 (6), F681-F692. doi: 10.1152/ajprenal.00241.2013
2014
Journal Article
Fibronectin and transforming growth factor beta contribute to erythropoietin resistance and maladaptive cardiac hypertrophy
Morais, Christudas, Small, David M., Vesey, David A., Martin, Jennifer, Johnson, David W. and Gobe, Glenda C. (2014). Fibronectin and transforming growth factor beta contribute to erythropoietin resistance and maladaptive cardiac hypertrophy. Biochemical and Biophysical Research Communications, In Press, Corrected Proof (3), 1-6. doi: 10.1016/j.bbrc.2014.01.047
2014
Journal Article
Dialysate interleukin-6 predicts increasing peritoneal solute transport rate in incident peritoneal dialysis patients
Cho, Yeoungjee, Johnson, David W., Vesey, David A., Hawley, Carmel M., Pascoe, Elaine M., Clarke, Margaret, Topley, Nicholas and on behalf of the balANZ Trial Investigators (2014). Dialysate interleukin-6 predicts increasing peritoneal solute transport rate in incident peritoneal dialysis patients. BMC Nephrology, 15 (1) 8. doi: 10.1186/1471-2369-15-8
2014
Conference Publication
Mitochondrial targeting of superoxide by Mitoq improves metabolic renal dysfunction
Ward, M. S., Flemming, N. B., Gallo, L. A., Fotheringham, A., Gobe, G., Vesey, D. and Forbes, J. M. (2014). Mitochondrial targeting of superoxide by Mitoq improves metabolic renal dysfunction. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne Australia, 25–27 August 2014. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301
2014
Conference Publication
Decreasing apoptosis repressor with caspase recruitment domain (ARC) is associated with disease progression and drug resistance of renal cell carcinoma
Ng, K. L., Wood, S. T., Ding, J. C., Jayasuriya, T. S., Vesey, D. A., Gobe, G. C. and Morais, C. (2014). Decreasing apoptosis repressor with caspase recruitment domain (ARC) is associated with disease progression and drug resistance of renal cell carcinoma. 67th Annual Scientific Meeting of the Urological-Society-of-Australia-and-New-Zealand, Brisbane, Australia, Mar 16-19, 2014. West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/bju.12618
2014
Conference Publication
Hepatic fibrosis is associated with small intestinal permeability in chronic liver disease due to hepatitis C, hepatitis B and non-alcoholic fatty liver disease, in subjects without ascites. A prospective cohort study using non-invasive techniques
Raj, Ashok, Holtmann, Gerald, Bhat, Purnima, Fletcher, Linda, Tran, Cuong, Vesey, David and Macdonald, Graeme (2014). Hepatic fibrosis is associated with small intestinal permeability in chronic liver disease due to hepatitis C, hepatitis B and non-alcoholic fatty liver disease, in subjects without ascites. A prospective cohort study using non-invasive techniques. Asian Pacific Digestive Week, Bali, Indonesia, 22‐25, 2014. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia . doi: 10.1111/jgh.12766_2
2013
Journal Article
Protein-bound uremic toxins, inflammation and oxidative stress: A cross-sectional study in stage 3-4 chronic kidney disease
Rossi, M., Campbell, K.L., Johnson, D.W., Stanton, T., Vesey, D.A., Coombes, J.S., Weston, K.S., Hawley, C.M., McWhinney, B.C., Ungerer, J.P.J. and Isbel, N. (2013). Protein-bound uremic toxins, inflammation and oxidative stress: A cross-sectional study in stage 3-4 chronic kidney disease. Archives of Medical Research, 45 (4), 309-317. doi: 10.1016/j.arcmed.2014.04.002
2013
Journal Article
Use of high-dose erythropoietin for repair after injury: A comparison of outcomes in heart and kidney
Gobe, Glenda C., Morais, Christudas, Vesey, David A. and Johnson, David W. (2013). Use of high-dose erythropoietin for repair after injury: A comparison of outcomes in heart and kidney. Journal of Nephropathology, 2 (3), 154-165. doi: 10.12860/JNP.2013.27
2013
Journal Article
PAR2-induced inflammatory responses in human kidney tubular epithelial cells
Vesey, David A., Suen, Jacky Y., Seow, Vernon, Lohman, Rink-Jan, Liu, Ligong, Gobe, Glenda C., Johnson, David W. and Fairlie, David P. (2013). PAR2-induced inflammatory responses in human kidney tubular epithelial cells. American Journal of Physiology - Renal Physiology, 304 (6), F737-F750. doi: 10.1152/ajprenal.00540.2012
2013
Conference Publication
Curcumin attenuates growth of established renal cell carcinoma through suppression of nuclear factor-kappa B
Morais, C., Vesey, D., Johnson, D., Wood, S. and Gobe, G. (2013). Curcumin attenuates growth of established renal cell carcinoma through suppression of nuclear factor-kappa B. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane, QLD Australia, 9-11 September 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12121
2013
Conference Publication
Erythropoietin Delivered for Protection From Acute Kidney Injury May Have Secondary Benefits in Protecting Heart
Morais, Christudas, Vesey, David A., Johnson, David W. and Gobe, Glenda C. (2013). Erythropoietin Delivered for Protection From Acute Kidney Injury May Have Secondary Benefits in Protecting Heart. 50th European Renal Association European Dialysis and Transplant Association Congress, Istanbul Turkey, 18-21 May 2013. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ndt/gft107
2013
Journal Article
Functional significance of erythropoietin in renal cell carcinoma
Morais, Christudas, Johnson, David W., Vesey, David A. and Gobe, Glenda C. (2013). Functional significance of erythropoietin in renal cell carcinoma. BMC Cancer, 13 (1) 14, 14.1-14.7. doi: 10.1186/1471-2407-13-14
2012
Journal Article
Evidence for steroidogenic potential in human prostate cell lines and tissues
Bennett, Nigel C., Hooper, John D., Lambie, Duncan, Lee, Cheok S., Yang, Tao, Vesey, David A., Samaratunga, Hemamali, Johnson, David W. and Gobe, Glenda C. (2012). Evidence for steroidogenic potential in human prostate cell lines and tissues. American Journal of Pathology, 181 (3), 1078-1087. doi: 10.1016/j.ajpath.2012.06.009
2012
Journal Article
Patient samples of renal cell carcinoma show reduced expression of TRAF1 compared with normal kidney and functional studies in vitro indicate TRAF1 promotes apoptosis: Potential for targeted therapy
Rajandram, Retnagowri, Bennett, Nigel C., Wang, Zhiqiang, Perry-Keene, Joanna, Vesey, David A., Johnson, David W. and Gobe, Glenda C. (2012). Patient samples of renal cell carcinoma show reduced expression of TRAF1 compared with normal kidney and functional studies in vitro indicate TRAF1 promotes apoptosis: Potential for targeted therapy. Pathology, 44 (5), 453-459. doi: 10.1097/PAT.0b013e3283557748
2012
Journal Article
An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats
Lohman, Rink-Jan, Cotterell, Adam J., Barry, Grant D., Liu, Ligong, Suen, Jacky Y., Vesey, David A. and Fairlie, David P. (2012). An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats. The FASEB Journal, 26 (7), 2877-2887. doi: 10.1096/fj.11-201004
Funding
Past funding
Supervision
Availability
- Associate Professor David Vesey is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Exploring Magnetic Resonance for Differentiating between Progressive and Non-Progressive Chronic Kidney Disease
Associate Advisor
Other advisors: Dr Robert Ellis, Associate Professor Ross Francis
-
Doctor Philosophy
Exploring Magnetic Resonance for Differentiating between Progressive and Non-Progressive Chronic Kidney Disease
Associate Advisor
Other advisors: Associate Professor Ross Francis, Dr Robert Ellis
Completed supervision
-
2021
Doctor Philosophy
Clinical Biobanking and the Distinguishing Risk of Progressive Chronic Kidney Disease Study
Associate Advisor
-
2020
Doctor Philosophy
Exploring Resistance of Renal Cell Carcinoma to Sunitinib Therapy
Associate Advisor
Other advisors: Professor Hemamali Samaratunga
-
2020
Doctor Philosophy
The role of the adipose tissue microenvironment in kidney cancer
Associate Advisor
Other advisors: Professor David Johnson
-
2016
Doctor Philosophy
Bioactive compounds from Australian Blacklip Abalone (Haliotis rubra) processing waste
Associate Advisor
-
2009
Doctor Philosophy
Targeting genes for identification and treatment of renal cell carcinoma
Associate Advisor
Other advisors: Professor David Johnson
Media
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