Associate Professor David Vesey
Associate Professor

David Vesey

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Background

David graduated from the University of London with a BSc (Hons) in biochemistry (King’s College) and PhD which investigated the role of epidermal growth factor receptors in liver regeneration (Imperial College). Since then he has worked on a variety of projects including; immunoassay development (Ortho Clinical Diagnostics); artificial liver machine development (Imperial College); and p53 mutations in liver cancer (QIMR). He joined the Department of Nephrology at the Princess Alexandra Hospital in Brisbane in 1999. He is a senior lecturer in The University of Queensland Faculty of Medicine, a senior member of the UQ Kidney Disease Research Laboratory and manages the Princess Alexandra Hospital Endotoxin Testing Service.

His main research interests are in the area of renal tubulointerstitial fibrosis, inflammation and also the mechanisms of renal cancer development – particularly the role that cytokines and growth factors play in these processes. Current projects include the role of protease activated receptor-2 in renal scarring, inflammation and cancer, the mechanism of heavy metal toxicity in the kidney and the renoprotective properties of erythropoietin. The Princess Alexandra Hospital Endotoxin Testing Service routinely tests samples from dialysis units throughout Queensland.

Availability

Associate Professor David Vesey is:
Available for supervision

Fields of research

Clinical sciences

Qualifications

  • Bachelor of Biochemistry, King's College London
  • Doctor of Philosophy of Gastroenterology and Hepatology, Imperial College London

Search Professor David Vesey’s works on UQ eSpace

176 works between 1991 and 2025
All (176) Journal Article (116) Book Chapter (1) Conference Publication (59)

61 - 80 of 176 works

2017

Journal Article

Factors associated with acutely elevated serum creatinine following radical tumour nephrectomy: the Correlates of Kidney Dysfunction-Tumour Nephrectomy Database study

Ellis, Robert J., Del Vecchio, Sharon J., Ng, Keng Lim, Dimeski, Goce, Pascoe, Elaine M., Hawley, Carmel M., Johnson, David W., Vesey, David A., Coombes, Jeff S., Morais, Christudas, Francis, Ross S., Wood, Simon T. and Gobe, Glenda C. (2017). Factors associated with acutely elevated serum creatinine following radical tumour nephrectomy: the Correlates of Kidney Dysfunction-Tumour Nephrectomy Database study. Translational Andrology and Urology, 6 (5), 899-909. doi: 10.21037/tau.2017.08.15

Factors associated with acutely elevated serum creatinine following radical tumour nephrectomy: the Correlates of Kidney Dysfunction-Tumour Nephrectomy Database study

2017

Journal Article

Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies

Shen, Kunyu, Johnson, David W., Vesey, David A., McGuckin, Michael A. and Gobe, Glenda C. (2017). Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies. Cell Stress and Chaperones, 23 (3), 317-334. doi: 10.1007/s12192-017-0844-3

Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies

2017

Journal Article

Current health risk assessment practice for dietary cadmium: data from different countries

Satarug, Soisungwan, Vesey, David A. and Gobe, Glenda C. (2017). Current health risk assessment practice for dietary cadmium: data from different countries. Food and Chemical Toxicology, 106 (A), 430-445. doi: 10.1016/j.fct.2017.06.013

Current health risk assessment practice for dietary cadmium: data from different countries

2017

Journal Article

Maslinic Acid Inhibits Proliferation of Renal Cell Carcinoma Cell Lines and Suppresses Angiogenesis of Endothelial Cells

Thakor, Parth, Song, Wenzhe, Subramanian, Ramalingam B., Thakkar, Vasudev R., Vesey, David A. and Gobe, Glenda C. (2017). Maslinic Acid Inhibits Proliferation of Renal Cell Carcinoma Cell Lines and Suppresses Angiogenesis of Endothelial Cells. Journal of Kidney Cancer and Vhl, 4 (1), 16-24. doi: 10.15586/jkcvhl.2017.64

Maslinic Acid Inhibits Proliferation of Renal Cell Carcinoma Cell Lines and Suppresses Angiogenesis of Endothelial Cells

2017

Journal Article

Health risk assessment of dietary cadmium intake: do current guidelines indicate how much is safe?

Satarug, Soisungwan, Vesey, David A. and Gobe, Glenda C. (2017). Health risk assessment of dietary cadmium intake: do current guidelines indicate how much is safe?. Environmental Health Perspectives, 125 (3), 284-288. doi: 10.1289/EHP108

Health risk assessment of dietary cadmium intake: do current guidelines indicate how much is safe?

2017

Journal Article

Kidney cadmium toxicity, diabetes and high blood pressure: the perfect storm

Satarug, Soisungwan , Vesey, David A. and Gobe, Glenda C. (2017). Kidney cadmium toxicity, diabetes and high blood pressure: the perfect storm. The Tohoku Journal of Experimental Medicine, 241 (1), 65-87. doi: 10.1620/tjem.241.65

Kidney cadmium toxicity, diabetes and high blood pressure: the perfect storm

2017

Conference Publication

Elevated serum creatinine and acute kidney injury following radical tumour nephrectomy

Ellis, R. J., Del Vecchio, S. J., Ng, K. L., Pascoe, E. M., Hawley, C. M., Johnson, D. W., Dimeski, G., Vesey, D. A., Coombes, J. S., Morais, C., Francis, R. S., Wood, S. T. and Gobe, G. C. (2017). Elevated serum creatinine and acute kidney injury following radical tumour nephrectomy. 53rd Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Darwin, NT Australia, 4-6 September 2017. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.13104

Elevated serum creatinine and acute kidney injury following radical tumour nephrectomy

2016

Journal Article

The stress response of human proximal tubule cells to cadmium involves up-regulation of haemoxygenase 1 and metallothionein but not cytochrome P450 enzymes

Boonprasert, Kanyarat, Satarug, Soisungwan, Morais, Christudas, Gobe, Glenda C., Johnson, David W., Na-Bangchang, Kesara and Vesey, David A. (2016). The stress response of human proximal tubule cells to cadmium involves up-regulation of haemoxygenase 1 and metallothionein but not cytochrome P450 enzymes. Toxicology Letters, 249, 5-14. doi: 10.1016/j.toxlet.2016.02.016

The stress response of human proximal tubule cells to cadmium involves up-regulation of haemoxygenase 1 and metallothionein but not cytochrome P450 enzymes

2016

Journal Article

Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways

Gobe, Glenda C., Ng, Keng Lim, Small, David M., Vesey, David A., Johnson, David W., Samaratunga, Hemamali, Oliver, Kimberley, Wood, Simon, Barclay, Johanna L., Rajandram, Retnagowri, Li, Li and Morais, Christudas (2016). Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways. Biochemical and Biophysical Research Communications, 473 (1), 47-53. doi: 10.1016/j.bbrc.2016.03.048

Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways

2016

Conference Publication

Altered Proximal Small-Intestinal Permeability and Bacterial Translocation in Chronic Liver Disease in Relation to Hepatic Fibrosis and Disease Severity

Raj, Ashok S., Holtmann, Gerald, Fletcher, Linda, Vesey, David A., Hickman, Ingrid J., Shanahan, Erin R., Tran, Cuong D. and Macdonald, Graeme (2016). Altered Proximal Small-Intestinal Permeability and Bacterial Translocation in Chronic Liver Disease in Relation to Hepatic Fibrosis and Disease Severity. 57th Annual Meeting and Residents Fellow Conference of the Society-for-Surgery-of-the-Alimentary-Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American-Gastroenterological-Association (AGA), San Diego, CA United States, 21-24 May 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/S0016-5085(16)33950-6

Altered Proximal Small-Intestinal Permeability and Bacterial Translocation in Chronic Liver Disease in Relation to Hepatic Fibrosis and Disease Severity

2016

Journal Article

Indoxyl sulphate and kidney disease: causes, consequences and interventions

Ellis, Robert J., Small, David M., Vesey, David A., Johnson, David W., Francis, Ross, Vitetta, Luis, Gobe, Glenda C. and Morais, Christudas (2016). Indoxyl sulphate and kidney disease: causes, consequences and interventions. Nephrology, 21 (3), 170-177. doi: 10.1111/nep.12580

Indoxyl sulphate and kidney disease: causes, consequences and interventions

2016

Journal Article

Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity

Yau, Mei-Kwan, Liu, Ligong, Lim, Junxian, Lohman, Rink-Jan, Cotterell, Adam J., Suen, Jacky Y., Vesey, David A., Reid, Robert C. and Fairlie, David P. (2016). Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity. Bioorganic and Medicinal Chemistry Letters, 26 (3), 986-991. doi: 10.1016/j.bmcl.2015.12.048

Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity

2016

Journal Article

Differential anti-inflammatory activity of HDAC inhibitors in human macrophages and rat arthritis

Lohman, Rink-Jan, Iyer, Abishek, Fairlie, Thomas J., Cotterell, Adam, Gupta, Praveer, Reid, Robert C., Vesey, David A., Sweet, Matthew J. and Fairlie, David P. (2016). Differential anti-inflammatory activity of HDAC inhibitors in human macrophages and rat arthritis. Journal of Pharmacology and Experimental Therapeutics, 356 (2), 387-396. doi: 10.1124/jpet.115.229328

Differential anti-inflammatory activity of HDAC inhibitors in human macrophages and rat arthritis

2016

Conference Publication

Kidney function following radical tumour nephrectomy. A comparison of functional outcomes by pre-operative CKD stage

Ellis, R., Del Vecchio, S., Ng, K., Vesey, D., Francis, R., Wood, S. and Gobe, G. (2016). Kidney function following radical tumour nephrectomy. A comparison of functional outcomes by pre-operative CKD stage. The 15th Asian Pacific Congress of Nephrology (APCN) and 52nd ANZSN ASM, Perth, WA, Australia, 17–21 September 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12888

Kidney function following radical tumour nephrectomy. A comparison of functional outcomes by pre-operative CKD stage

2016

Conference Publication

Pharmacological Inhibition of Protease-Activated Receptor 2 (Par2) Reduces Crescent Formation in Rat Anti-Gbm Disease

Tesch, G., Han, Y., Vesey, D., Gobe, G., Lohman, R., Suen, J., Fairlie, D. and Nikolic-Paterson, D. (2016). Pharmacological Inhibition of Protease-Activated Receptor 2 (Par2) Reduces Crescent Formation in Rat Anti-Gbm Disease. 15th Asian Pacific Congress of Nephrology (APCN) and 52nd ANZSN ASM, Perth, WA, Australia, 17–21 September 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12887

Pharmacological Inhibition of Protease-Activated Receptor 2 (Par2) Reduces Crescent Formation in Rat Anti-Gbm Disease

2016

Journal Article

Higher dialysate matrix metalloproteinase-2 levels are associated with peritoneal membrane dysfunction

Cho, Yeoungjee, Johnson, David W., Vesey, David A., Hawley, Carmel M., Pascoe, Elaine M., Clarke, Margaret and Topley, Nicholas (2016). Higher dialysate matrix metalloproteinase-2 levels are associated with peritoneal membrane dysfunction. Peritoneal Dialysis International, 36 (1), 16-25. doi: 10.3747/pdi.2013.00274

Higher dialysate matrix metalloproteinase-2 levels are associated with peritoneal membrane dysfunction

2016

Journal Article

PAR2 modulators derived from GB88

Yau, Mei-Kwan, Liu, Ligong, Suen, Jacky Y., Lim, Junxian, Lohman, Rink-Jan, Jiang, Yuhong, Cotterell, Adam J., Barry, Grant D., Mak, Jeffrey Y. W., Vesey, David A., Reid, Robert C. and Fairlie, David P. (2016). PAR2 modulators derived from GB88. ACS Medicinal Chemistry Letters, 7 (12), 1179-1184. doi: 10.1021/acsmedchemlett.6b00306

PAR2 modulators derived from GB88

2016

Conference Publication

Inflammation in Dialysis

Dheda, S., Min, H., Van, Eps C., Johnson, D., Vesey, D., Healy, H., Hawley, C. and Fahim, M. (2016). Inflammation in Dialysis. The 15th Asian Pacific Congress of Nephrology (APCN) and 52nd ANZSN ASM, Perth, Western Australia, 17–21 September 2016. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1111/nep.12887

Inflammation in Dialysis

2016

Conference Publication

Protease activated-receptor-2 induced inflammation and fibrosis is mediated in part through activation of transforming growth factor-beta signalling

Owens, E., Iyer, A., Morais, C., Lohman, R., Suen, J., Johnson, D., Nikolic-Paterson, D., Gobe, G., Fairlie, D. and Vesey, D. (2016). Protease activated-receptor-2 induced inflammation and fibrosis is mediated in part through activation of transforming growth factor-beta signalling. The 15th Asian Pacific Congress of Nephrology (APCN) and 52nd ANZSN ASM, Perth Western Australia, 17–21 September 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12887

Protease activated-receptor-2 induced inflammation and fibrosis is mediated in part through activation of transforming growth factor-beta signalling

2015

Journal Article

Utility of urinary biomarkers in predicting loss of residual renal function: the balANZ trial

Cho, Yeoungjee, Johnson, David W., Vesey, David A., Hawley, Carmel M., Clarke, Margaret and Topley, Nicholas (2015). Utility of urinary biomarkers in predicting loss of residual renal function: the balANZ trial. Peritoneal Dialysis International, 35 (2), 159-171. doi: 10.3747/pdi.2013.00170

Utility of urinary biomarkers in predicting loss of residual renal function: the balANZ trial

Past funding

  • 2013 - 2015
    The application of adipose-derived stem cells and stem cell secretions to the treatment of renal disease.
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2013
    Enhancing erythropoietin therapy in ischaemia-reperfusion injury of heart and kidney
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Protease activated receptor 2 antagonist in inflammatory disease
    NHMRC Development Grant
    Open grant
  • 2009 - 2012
    Protease Activated Receptor 2 : A New Drug Target For Inflammatory Diseases and Cancer
    NHMRC Project Grant
    Open grant

Availability

Associate Professor David Vesey is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

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