Overview
Background
Associate professor David Vesey is a leading research scientist in The University of Queensland Centre for Kidney Disease Research at the Translational Research Institute and a senior scientist within the Department of Kidney and Transplant Services at the Princess Alexandra Hospital. He is a graduate of Kings College and Imperial Collage, London University. Postdoctoral studies were at London University and The University of Queensland.
His main research interests are in the area of kidney tubulointerstitial fibrosis, inflammation and cancer – particularly the role that cytokines and growth factors play in these processes. Current projects include the role of protease activated receptor-2 in kidney inflammation and fibrosis, and the mechanism of heavy metal toxicity in the kidney. He manages the Princess Alexandra Hospital Endotoxin Testing Service which routinely tests samples from dialysis units throughout Queensland.
Availability
- Associate Professor David Vesey is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Biochemistry, King's College London
- Doctor of Philosophy of Gastroenterology and Hepatology, Imperial College London
Works
Search Professor David Vesey’s works on UQ eSpace
2018
Journal Article
Is renal tubular cadmium toxicity clinically relevant?
Boonprasert, Kanyarat, Vesey, David A., Gobe, Glenda C., Ruenweerayut, Ronnatrai, Johnson, David W., Na-Bangchang, Kesara and Satarug, Soisungwan (2018). Is renal tubular cadmium toxicity clinically relevant?. Clinical Kidney Journal, 11 (5), 681-687. doi: 10.1093/ckj/sfx153
2018
Conference Publication
PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidney
Han, Y., Ma, F., Ozols, E., Chew, P., Vesey, D., Gobe, G., Morais, C., Lohman, R., Suen, J., Fairlie, D. and Nikolic-Paterson, D. (2018). PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidney. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8–12 September 2018. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.13441
2018
Journal Article
Indoxyl Sulfate Induces Apoptosis and Hypertrophy in Human Kidney Proximal Tubular Cells
Ellis, Robert J., Small, David M., Ng, Keng Lim, Vesey, David A., Vitetta, Luis, Francis, Ross S., Gobe, Glenda C. and Morais, Christudas (2018). Indoxyl Sulfate Induces Apoptosis and Hypertrophy in Human Kidney Proximal Tubular Cells. Toxicologic Pathology, 46 (4), 192623318768171-459. doi: 10.1177/0192623318768171
2018
Journal Article
Characterisation of the Morphological, Functional and Molecular Changes in Sunitinib-Resistant Renal Cell Carcinoma Cells
Kamli, Hossam, Gobe, Glenda C., Li, Li, Vesey, David A. and Morais, Christudas (2018). Characterisation of the Morphological, Functional and Molecular Changes in Sunitinib-Resistant Renal Cell Carcinoma Cells. Journal of Kidney Cancer and VHL, 5 (3), 1-9. doi: 10.15586/jkcvhl.2018.106
2018
Conference Publication
End-stage kidney disease following surgical management of kidney cancer in Queensland
Ellis, R., Edey, D., Del Vecchio, S., Mcstea, M., Hawley, C., Johnson, D., Vesey, D., Morais, C., Jordan, S., Francis, R., Wood, S. and Gobe, G. (2018). End-stage kidney disease following surgical management of kidney cancer in Queensland. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8-12 September 2018. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.13466
2017
Journal Article
Factors associated with acutely elevated serum creatinine following radical tumour nephrectomy: the Correlates of Kidney Dysfunction-Tumour Nephrectomy Database study
Ellis, Robert J., Del Vecchio, Sharon J., Ng, Keng Lim, Dimeski, Goce, Pascoe, Elaine M., Hawley, Carmel M., Johnson, David W., Vesey, David A., Coombes, Jeff S., Morais, Christudas, Francis, Ross S., Wood, Simon T. and Gobe, Glenda C. (2017). Factors associated with acutely elevated serum creatinine following radical tumour nephrectomy: the Correlates of Kidney Dysfunction-Tumour Nephrectomy Database study. Translational Andrology and Urology, 6 (5), 899-909. doi: 10.21037/tau.2017.08.15
2017
Journal Article
Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies
Shen, Kunyu, Johnson, David W., Vesey, David A., McGuckin, Michael A. and Gobe, Glenda C. (2017). Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies. Cell Stress and Chaperones, 23 (3), 317-334. doi: 10.1007/s12192-017-0844-3
2017
Journal Article
Current health risk assessment practice for dietary cadmium: data from different countries
Satarug, Soisungwan, Vesey, David A. and Gobe, Glenda C. (2017). Current health risk assessment practice for dietary cadmium: data from different countries. Food and Chemical Toxicology, 106 (A), 430-445. doi: 10.1016/j.fct.2017.06.013
2017
Journal Article
Maslinic Acid Inhibits Proliferation of Renal Cell Carcinoma Cell Lines and Suppresses Angiogenesis of Endothelial Cells
Thakor, Parth, Song, Wenzhe, Subramanian, Ramalingam B., Thakkar, Vasudev R., Vesey, David A. and Gobe, Glenda C. (2017). Maslinic Acid Inhibits Proliferation of Renal Cell Carcinoma Cell Lines and Suppresses Angiogenesis of Endothelial Cells. Journal of Kidney Cancer and Vhl, 4 (1), 16-24. doi: 10.15586/jkcvhl.2017.64
2017
Journal Article
Health risk assessment of dietary cadmium intake: do current guidelines indicate how much is safe?
Satarug, Soisungwan, Vesey, David A. and Gobe, Glenda C. (2017). Health risk assessment of dietary cadmium intake: do current guidelines indicate how much is safe?. Environmental Health Perspectives, 125 (3), 284-288. doi: 10.1289/EHP108
2017
Conference Publication
Elevated serum creatinine and acute kidney injury following radical tumour nephrectomy
Ellis, R. J., Del Vecchio, S. J., Ng, K. L., Pascoe, E. M., Hawley, C. M., Johnson, D. W., Dimeski, G., Vesey, D. A., Coombes, J. S., Morais, C., Francis, R. S., Wood, S. T. and Gobe, G. C. (2017). Elevated serum creatinine and acute kidney injury following radical tumour nephrectomy. 53rd Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Darwin, NT Australia, 4-6 September 2017. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.13104
2017
Journal Article
Kidney cadmium toxicity, diabetes and high blood pressure: the perfect storm
Satarug, Soisungwan , Vesey, David A. and Gobe, Glenda C. (2017). Kidney cadmium toxicity, diabetes and high blood pressure: the perfect storm. The Tohoku Journal of Experimental Medicine, 241 (1), 65-87. doi: 10.1620/tjem.241.65
2016
Journal Article
The stress response of human proximal tubule cells to cadmium involves up-regulation of haemoxygenase 1 and metallothionein but not cytochrome P450 enzymes
Boonprasert, Kanyarat, Satarug, Soisungwan, Morais, Christudas, Gobe, Glenda C., Johnson, David W., Na-Bangchang, Kesara and Vesey, David A. (2016). The stress response of human proximal tubule cells to cadmium involves up-regulation of haemoxygenase 1 and metallothionein but not cytochrome P450 enzymes. Toxicology Letters, 249, 5-14. doi: 10.1016/j.toxlet.2016.02.016
2016
Journal Article
Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways
Gobe, Glenda C., Ng, Keng Lim, Small, David M., Vesey, David A., Johnson, David W., Samaratunga, Hemamali, Oliver, Kimberley, Wood, Simon, Barclay, Johanna L., Rajandram, Retnagowri, Li, Li and Morais, Christudas (2016). Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways. Biochemical and Biophysical Research Communications, 473 (1), 47-53. doi: 10.1016/j.bbrc.2016.03.048
2016
Conference Publication
Altered Proximal Small-Intestinal Permeability and Bacterial Translocation in Chronic Liver Disease in Relation to Hepatic Fibrosis and Disease Severity
Raj, Ashok S., Holtmann, Gerald, Fletcher, Linda, Vesey, David A., Hickman, Ingrid J., Shanahan, Erin R., Tran, Cuong D. and Macdonald, Graeme (2016). Altered Proximal Small-Intestinal Permeability and Bacterial Translocation in Chronic Liver Disease in Relation to Hepatic Fibrosis and Disease Severity. 57th Annual Meeting and Residents Fellow Conference of the Society-for-Surgery-of-the-Alimentary-Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American-Gastroenterological-Association (AGA), San Diego, CA United States, 21-24 May 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/S0016-5085(16)33950-6
2016
Journal Article
Indoxyl sulphate and kidney disease: causes, consequences and interventions
Ellis, Robert J., Small, David M., Vesey, David A., Johnson, David W., Francis, Ross, Vitetta, Luis, Gobe, Glenda C. and Morais, Christudas (2016). Indoxyl sulphate and kidney disease: causes, consequences and interventions. Nephrology, 21 (3), 170-177. doi: 10.1111/nep.12580
2016
Journal Article
Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity
Yau, Mei-Kwan, Liu, Ligong, Lim, Junxian, Lohman, Rink-Jan, Cotterell, Adam J., Suen, Jacky Y., Vesey, David A., Reid, Robert C. and Fairlie, David P. (2016). Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity. Bioorganic and Medicinal Chemistry Letters, 26 (3), 986-991. doi: 10.1016/j.bmcl.2015.12.048
2016
Journal Article
Differential anti-inflammatory activity of HDAC inhibitors in human macrophages and rat arthritis
Lohman, Rink-Jan, Iyer, Abishek, Fairlie, Thomas J., Cotterell, Adam, Gupta, Praveer, Reid, Robert C., Vesey, David A., Sweet, Matthew J. and Fairlie, David P. (2016). Differential anti-inflammatory activity of HDAC inhibitors in human macrophages and rat arthritis. Journal of Pharmacology and Experimental Therapeutics, 356 (2), 387-396. doi: 10.1124/jpet.115.229328
2016
Conference Publication
Pharmacological Inhibition of Protease-Activated Receptor 2 (Par2) Reduces Crescent Formation in Rat Anti-Gbm Disease
Tesch, G., Han, Y., Vesey, D., Gobe, G., Lohman, R., Suen, J., Fairlie, D. and Nikolic-Paterson, D. (2016). Pharmacological Inhibition of Protease-Activated Receptor 2 (Par2) Reduces Crescent Formation in Rat Anti-Gbm Disease. 15th Asian Pacific Congress of Nephrology (APCN) and 52nd ANZSN ASM, Perth, WA, Australia, 17–21 September 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12887
2016
Journal Article
Higher dialysate matrix metalloproteinase-2 levels are associated with peritoneal membrane dysfunction
Cho, Yeoungjee, Johnson, David W., Vesey, David A., Hawley, Carmel M., Pascoe, Elaine M., Clarke, Margaret and Topley, Nicholas (2016). Higher dialysate matrix metalloproteinase-2 levels are associated with peritoneal membrane dysfunction. Peritoneal Dialysis International, 36 (1), 16-25. doi: 10.3747/pdi.2013.00274
Funding
Past funding
Supervision
Availability
- Associate Professor David Vesey is:
- Available for supervision
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Supervision history
Completed supervision
-
2025
Doctor Philosophy
Exploring Magnetic Resonance for Differentiating between Progressive and Non-Progressive Chronic Kidney Disease
Associate Advisor
Other advisors: Dr Robert Ellis, Associate Professor Ross Francis
-
2021
Doctor Philosophy
Clinical Biobanking and the Distinguishing Risk of Progressive Chronic Kidney Disease Study
Associate Advisor
-
2020
Doctor Philosophy
Exploring Resistance of Renal Cell Carcinoma to Sunitinib Therapy
Associate Advisor
Other advisors: Professor Hemamali Samaratunga, Honorary Professor Li Li
-
2020
Doctor Philosophy
The role of the adipose tissue microenvironment in kidney cancer
Associate Advisor
Other advisors: Professor David Johnson, Dr Sumaira Hasnain
-
2016
Doctor Philosophy
Bioactive compounds from Australian Blacklip Abalone (Haliotis rubra) processing waste
Associate Advisor
-
2009
Doctor Philosophy
Targeting genes for identification and treatment of renal cell carcinoma
Associate Advisor
Other advisors: Professor David Johnson
Media
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