Overview
Background
David graduated from the University of London with a BSc (Hons) in biochemistry (King’s College) and PhD which investigated the role of epidermal growth factor receptors in liver regeneration (Imperial College). Since then he has worked on a variety of projects including; immunoassay development (Ortho Clinical Diagnostics); artificial liver machine development (Imperial College); and p53 mutations in liver cancer (QIMR). He joined the Department of Nephrology at the Princess Alexandra Hospital in Brisbane in 1999. He is a senior lecturer in The University of Queensland Faculty of Medicine, a senior member of the UQ Kidney Disease Research Laboratory and manages the Princess Alexandra Hospital Endotoxin Testing Service.
His main research interests are in the area of renal tubulointerstitial fibrosis, inflammation and also the mechanisms of renal cancer development – particularly the role that cytokines and growth factors play in these processes. Current projects include the role of protease activated receptor-2 in renal scarring, inflammation and cancer, the mechanism of heavy metal toxicity in the kidney and the renoprotective properties of erythropoietin. The Princess Alexandra Hospital Endotoxin Testing Service routinely tests samples from dialysis units throughout Queensland.
Availability
- Associate Professor David Vesey is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Biochemistry, King's College London
- Doctor of Philosophy of Gastroenterology and Hepatology, Imperial College London
Works
Search Professor David Vesey’s works on UQ eSpace
2020
Journal Article
Development of a biomarker panel to distinguish risk of progressive chronic kidney disease
Owens, Evan, Tan, Ken-Soon, Ellis, Robert, Del Vecchio, Sharon, Humphries, Tyrone, Lennan, Erica, Vesey, David, Healy, Helen, Hoy, Wendy and Gobe, Glenda (2020). Development of a biomarker panel to distinguish risk of progressive chronic kidney disease. Biomedicines, 8 (12) 606, 606-16. doi: 10.3390/biomedicines8120606
2020
Journal Article
Cadmium and lead exposure, nephrotoxicity, and mortality
Satarug, Soisungwan, Gobe, Glenda C., Vesey, David A. and Phelps, Kenneth R. (2020). Cadmium and lead exposure, nephrotoxicity, and mortality. Toxics, 8 (4) 86, 86-42. doi: 10.3390/toxics8040086
2020
Journal Article
[Retracted publication] Establishing a stable platform for the measurement of blood endotoxin levels in the dialysis population
Dheda, Shyam, Min, Hongjin, Vesey, David, Hawley, Carmel, Johnson, David W. and Fahim, Magid (2020). [Retracted publication] Establishing a stable platform for the measurement of blood endotoxin levels in the dialysis population. Diagnosis, 8 (2), 249-256. doi: 10.1515/dx-2019-0088
2020
Journal Article
A comparison of the nephrotoxicity of low doses of cadmium and lead
Satarug, Soisungwan, Gobe, Glenda C., Ujjin, Pailin and Vesey, David A. (2020). A comparison of the nephrotoxicity of low doses of cadmium and lead. Toxics, 8 (1) 18, 18. doi: 10.3390/toxics8010018
2019
Journal Article
The source and pathophysiologic significance of excreted cadmium
Satarug, Soisungwan, Vesey, David A., Ruangyuttikarn, Werawan, Nishijo, Muneko, Gobe, Glenda C. and Phelps, Kenneth R. (2019). The source and pathophysiologic significance of excreted cadmium. Toxics, 7 (4) 55, 55. doi: 10.3390/toxics7040055
2019
Journal Article
A cost-effective three-dimensional culture platform functionally mimics the adipose tissue microenvironment surrounding the kidney
Shen, Kunyu, Vesey, David A., Hasnain, Sumaira Z., Zhao, Kong-Nan, Wang, Haolu, Johnson, David W., Saunders, Nicholas, Burgess, Melinda and Gobe, Glenda C. (2019). A cost-effective three-dimensional culture platform functionally mimics the adipose tissue microenvironment surrounding the kidney. Biochemical and Biophysical Research Communications, 522 (3), 736-742. doi: 10.1016/j.bbrc.2019.11.119
2019
Journal Article
Protease-activated receptor 2 does not contribute to renal inflammation or fibrosis in the obstructed kidney
Ma, Frank Y., Han, Yingjie, Ozols, Elyce, Chew, Phyllis, Vesey, David A., Gobe, Glenda C., Morais, Christudas, Lohman, Rink-Jan, Suen, Jacky Y., Johnson, David W., Fairlie, David P. and Nikolic-Paterson, David J. (2019). Protease-activated receptor 2 does not contribute to renal inflammation or fibrosis in the obstructed kidney. Nephrology, 24 (9) nep.13635, 983-991. doi: 10.1111/nep.13635
2019
Journal Article
Chronic exposure to cadmium is associated with a marked reduction in glomerular filtration rate
Satarug, Soisungwan, Boonprasert, Kanyarat, Gobe, Glenda C., Ruenweerayut, Ronnatrai, Johnson, David W., Na-Bangchang, Kesara and Vesey, David A. (2019). Chronic exposure to cadmium is associated with a marked reduction in glomerular filtration rate. Clinical Kidney Journal, 12 (4), 468-475. doi: 10.1093/ckj/sfy113
2019
Journal Article
Dysbiosis of the Duodenal Mucosal Microbiota Is Associated With Increased Small Intestinal Permeability in Chronic Liver Disease
Raj, Ashok S., Shanahan, Erin R., Tran, Cuong D., Bhat, Purnima, Fletcher, Linda M., Vesey, David A., Morrison, Mark, Holtmann, Gerald and Macdonald, Graeme A. (2019). Dysbiosis of the Duodenal Mucosal Microbiota Is Associated With Increased Small Intestinal Permeability in Chronic Liver Disease. Clinical and Translational Gastroenterology, 10 (8) e00068, e00068. doi: 10.14309/ctg.0000000000000068
2019
Journal Article
The inverse association of glomerular function and urinary β2-MG excretion and its implications for cadmium health risk assessment
Satarug, Soisungwan, Vesey, David A., Nishijo, Muneko, Ruangyuttikarn, Werawan and Gobe, Glenda C. (2019). The inverse association of glomerular function and urinary β2-MG excretion and its implications for cadmium health risk assessment. Environmental Research, 173, 40-47. doi: 10.1016/j.envres.2019.03.026
2019
Journal Article
Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease
Owens, Evan P., Vesey, David A., Kassianos, Andrew J., Healy, Helen, Hoy, Wendy E. and Gobe, Glenda C. (2019). Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease. Translational Andrology and Urology, 8 (S2), S175-S183. doi: 10.21037/tau.2018.11.03
2019
Journal Article
Pharmacological inhibition of protease-activated receptor-2 reduces crescent formation in rat nephrotoxic serum nephritis
Han, Yingjie, Tian, Lifang, Ma, Frank, Tesch, Greg, Vesey, David A., Gobe, Glenda C., Lohman, Rink-Jan, Morais, Christudas, Suen, Jacky Y., Fairlie, David P. and Nikolic-Paterson, David J. (2019). Pharmacological inhibition of protease-activated receptor-2 reduces crescent formation in rat nephrotoxic serum nephritis. Clinical and Experimental Pharmacology and Physiology, 46 (5) 1440-1681.13077, 456-464. doi: 10.1111/1440-1681.13077
2019
Journal Article
GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma
Shen, Kunyu, Vesey, David A., Ellis, Robert J., Del Vecchio, Sharon Juliet, Cho, Yeoungjee, Teixeira-Pinto, Armando, McGuckin, Michael A., Johnson, David W. and Gobe, Glenda C. (2019). GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma. PLoS One, 14 (1) e0210246, e0210246. doi: 10.1371/journal.pone.0210246
2018
Journal Article
Conditioned medium from stimulated macrophages inhibits growth but induces an inflammatory phenotype in breast cancer cells
Song, Wenzhe, Thakor, Parth, Vesey, David A., Gobe, Glenda C. and Morais, Christudas (2018). Conditioned medium from stimulated macrophages inhibits growth but induces an inflammatory phenotype in breast cancer cells. Biomedicine and Pharmacotherapy, 106, 247-254. doi: 10.1016/j.biopha.2018.06.126
2018
Journal Article
Leptin and its receptor: can they help to differentiate chromophobe renal cell carcinoma from renal oncocytoma?
Ng, K. L., Del Vecchio, S. J., Samaratunga, H., Morais, C., Rajandram, R., Vesey, D. A., Wood, S. T. and Gobe, G. C. (2018). Leptin and its receptor: can they help to differentiate chromophobe renal cell carcinoma from renal oncocytoma?. Pathology, 50 (5), 504-510. doi: 10.1016/j.pathol.2018.01.007
2018
Journal Article
Is renal tubular cadmium toxicity clinically relevant?
Boonprasert, Kanyarat, Vesey, David A., Gobe, Glenda C., Ruenweerayut, Ronnatrai, Johnson, David W., Na-Bangchang, Kesara and Satarug, Soisungwan (2018). Is renal tubular cadmium toxicity clinically relevant?. Clinical Kidney Journal, 11 (5), 681-687. doi: 10.1093/ckj/sfx153
2018
Journal Article
Characterisation of the Morphological, Functional and Molecular Changes in Sunitinib-Resistant Renal Cell Carcinoma Cells
Kamli, Hossam, Gobe, Glenda C., Li, Li, Vesey, David A. and Morais, Christudas (2018). Characterisation of the Morphological, Functional and Molecular Changes in Sunitinib-Resistant Renal Cell Carcinoma Cells. Journal of Kidney Cancer and VHL, 5 (3), 1-9. doi: 10.15586/jkcvhl.2018.106
2018
Conference Publication
End-stage kidney disease following surgical management of kidney cancer in Queensland
Ellis, R., Edey, D., Del Vecchio, S., Mcstea, M., Hawley, C., Johnson, D., Vesey, D., Morais, C., Jordan, S., Francis, R., Wood, S. and Gobe, G. (2018). End-stage kidney disease following surgical management of kidney cancer in Queensland. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8-12 September 2018. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.13466
2018
Conference Publication
PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidney
Han, Y., Ma, F., Ozols, E., Chew, P., Vesey, D., Gobe, G., Morais, C., Lohman, R., Suen, J., Fairlie, D. and Nikolic-Paterson, D. (2018). PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidney. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8–12 September 2018. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.13441
2018
Journal Article
Indoxyl Sulfate Induces Apoptosis and Hypertrophy in Human Kidney Proximal Tubular Cells
Ellis, Robert J., Small, David M., Ng, Keng Lim, Vesey, David A., Vitetta, Luis, Francis, Ross S., Gobe, Glenda C. and Morais, Christudas (2018). Indoxyl Sulfate Induces Apoptosis and Hypertrophy in Human Kidney Proximal Tubular Cells. Toxicologic Pathology, 46 (4), 192623318768171-459. doi: 10.1177/0192623318768171
Funding
Past funding
Supervision
Availability
- Associate Professor David Vesey is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Exploring Magnetic Resonance for Differentiating between Progressive and Non-Progressive Chronic Kidney Disease
Associate Advisor
Other advisors: Dr Robert Ellis, Associate Professor Ross Francis
-
Doctor Philosophy
Exploring Magnetic Resonance for Differentiating between Progressive and Non-Progressive Chronic Kidney Disease
Associate Advisor
Other advisors: Associate Professor Ross Francis, Dr Robert Ellis
Completed supervision
-
2021
Doctor Philosophy
Clinical Biobanking and the Distinguishing Risk of Progressive Chronic Kidney Disease Study
Associate Advisor
-
2020
Doctor Philosophy
Exploring Resistance of Renal Cell Carcinoma to Sunitinib Therapy
Associate Advisor
Other advisors: Professor Hemamali Samaratunga
-
2020
Doctor Philosophy
The role of the adipose tissue microenvironment in kidney cancer
Associate Advisor
Other advisors: Professor David Johnson
-
2016
Doctor Philosophy
Bioactive compounds from Australian Blacklip Abalone (Haliotis rubra) processing waste
Associate Advisor
-
2009
Doctor Philosophy
Targeting genes for identification and treatment of renal cell carcinoma
Associate Advisor
Other advisors: Professor David Johnson
Media
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