Overview
Background
Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC Research). He is a Professor of Gynaecological Oncology since 2007, a Senior Medical Officer at Royal Brisbane & Women’s Hospital and a Visiting Medical Officer at St Andrews War Memorial Hospital and Buderim Private Hospital. He holds an Honorary title of Professor at UQ since 2006.
Professor Obermair is an internationally recognised leader in gynaecological oncology research and treatment and has lead the research team at QCGC Research since establishing it in 2003.
Availability
- Professor Andreas Obermair is:
- Available for supervision
Fields of research
Qualifications
- Doctoral Diploma of Medicine, International University Vienna
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
Research interests
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Clinical Trials
Decisions on cancer management ideally are based on the results of high-level evidence, obtained through clinical trials whenever possible. As a principle, a new (proposed better) intervention should be compared to the current standard treatment before being made available generally. Outside a clinical trial new treatments should not become available until evidence has become available to demonstrate superiority over the current standard treatment. Retrospective studies harbour the risk that biases influenced outcomes. At QCGC Research we engage in phase 2 and 3 clinical trials. In large phase trials, patients are allocated randomly to one of two or more interventions in order to minimise the risk of bias. Generally, patients treated within clinical trials have a better outcome compared to patients who are not treated in clinical trials. As the Director of Research Gynaecological Oncology I am currently involved in developing and managing clinical trials in gynaecological cancers.
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Translational Research
The focus of QCGC Research's translational research program is the application of new technology (molecular, biochemical, imaging and surgical) to prevention, detection and therapy for gynaecological cancers.
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Quality of Life Research
Cancer specialists are aware that not only the survival time but also the quality of life is a key factor in cancer treatment. This is especially important when two treatments are equally effective but cause different side-effects. My Quality-of-Life research focuses on ovarian, endometrial, cervical and vulval cancer. I wish to provide the best, most effective and modern treatment to my patients with least possible detriments to quality of life.
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Minimally Invasive Surgery
In Australia, around 30,000 hysterectomies are conducted annually to treat uterine cancer and various benign gynaecological conditions. While open abdominal surgery may be necessary in around 10% of cases, evidence shows that less-invasive approaches, such as total laparoscopic hysterectomy (TLH) can achieve better outcomes for women at a lower overall cost to the health system. Yet, in Queensland, four of ten hysterectomies are still conducted by open abdominal surgery. Our own research has shown that many Australian surgeons are keen to adopt new techniques such as TLH, but that the lack of systematic training and mentoring opportunities is the main impediment to practice-change. Together with gynaecological surgical teams at hospitals and industry support we developed a prototype for system-level transformative practice change in gynaecological surgery.
Research impacts
Professor Obermair is an innovative and skilled gynaecologic oncologist, surgical teacher and consumer advocate. His international leadership and research impact was acknowledged in 2020 by the Australian community, when he was awarded an NHMRC Investigator Fellowship Level 2 (2021-25). The national impact of his research was recognised in 2017, when he was awarded Cancer Australia’s Jeannie Ferris Recognition Award (2017), for outstanding achievements in clinical practice and research. He is deeply engaged in consumer involvement and co-founded and serves on the Board of the Cherish Foundation, a consumer-focussed organisation that funds clinical research in better treatments for women with gynaecological cancers.
Works
Search Professor Andreas Obermair’s works on UQ eSpace
2003
Journal Article
Thrombocytosis and anaemia in women with recurrent ovarian cancer prior to a second-line chemotherapy
Nather, A, Mayerhofer, K., Grimm, C., Hefler, L., Leodolter, S., Obermair, A. and Joura, E.A. (2003). Thrombocytosis and anaemia in women with recurrent ovarian cancer prior to a second-line chemotherapy. Anticancer Research, 23 (3), 2991-2994.
2003
Journal Article
Lack of impact of platinum dose intensity on the outcome of ovarian cancer patients: 10-year results of a prospective randomised phase III study comparing carboplatin-cisplatin with cyclophosphamide-cisplatin
Dittrich, C, Sevelda, P, Salzer, H, Obermair, A, Speiser, P, Breitenecker, G, Schemper, M, Kaider, A and Austrian Ovarian Canc Study Grp (2003). Lack of impact of platinum dose intensity on the outcome of ovarian cancer patients: 10-year results of a prospective randomised phase III study comparing carboplatin-cisplatin with cyclophosphamide-cisplatin. European Journal of Cancer, 39 (8), 1129-1140. doi: 10.1016/S0959-8049(03)00152-7
2002
Journal Article
Impact of multiple HPV infection on response to treatment and survival in patients receiving radical radiotherapy for cervical cancer
Bachtiary, B, Obermair, A, Dreier, B, Birner, P, Breitenecker, G, Knocke, TH, Selzer, E and Potter, R (2002). Impact of multiple HPV infection on response to treatment and survival in patients receiving radical radiotherapy for cervical cancer. International Journal of Cancer, 102 (3), 237-243. doi: 10.1002/ijc.10708
2002
Journal Article
Prognostic value of Laminin-5 in serous adenocarcinomas of the ovary
Kohlberger, P, Muller-Klingspor, V, Heinzl, A, Obermair, A, Breitenecker, G and Leodolter, S (2002). Prognostic value of Laminin-5 in serous adenocarcinomas of the ovary. Anticancer Research, 22 (6B), 3541-3544.
2002
Journal Article
The urethra during pelvic floor contraction: Observations on three-dimensional ultrasound
Umek, WH, Laml, T, Stutterecker, D, Obermair, A, Leodolter, S and Hanzal, E (2002). The urethra during pelvic floor contraction: Observations on three-dimensional ultrasound. Obstetrics and Gynecology, 100 (4), 796-800. doi: 10.1016/S0029-7844(02)02146-4
2002
Journal Article
Vascular endothelial growth factor splice variants and their prognostic value in breast and ovarian cancer
Stimpfl, M, Tong, D, Fasching, B, Schuster, E, Obermair, A, Leodolter, S and Zeillinger, R (2002). Vascular endothelial growth factor splice variants and their prognostic value in breast and ovarian cancer. Clinical Cancer Research, 8 (7), 2253-2259.
2002
Journal Article
Histopathologic correlation of high-resolution magnetic resonance imaging of human cervical tissue samples at 3 tesla - Validation of a technique
Csapo, B, Szeles, J, Helbich, TH, Klarhofer, M, Balassy, C, Pammer, J and Obermair, A (2002). Histopathologic correlation of high-resolution magnetic resonance imaging of human cervical tissue samples at 3 tesla - Validation of a technique. Investigative Radiology, 37 (7), 381-385. doi: 10.1097/00004424-200207000-00004
2002
Journal Article
Impact of videotaped information on frequency and confidence of breast self-examination
Janda, M, Stanek, C, Newman, B, Obermair, A and Trimmel, M (2002). Impact of videotaped information on frequency and confidence of breast self-examination. Breast Cancer Research and Treatment, 73 (1), 37-43. doi: 10.1023/A:1015264103561
2002
Journal Article
Serum VEGF levels in patients undergoing primary radiotherapy for cervical cancer: impact on progression-free survival
Bachtiary, B, Selzer, E, Knocke, TH, Potter, R and Obermair, A (2002). Serum VEGF levels in patients undergoing primary radiotherapy for cervical cancer: impact on progression-free survival. Cancer Letters, 179 (2), 197-203. doi: 10.1016/S0304-3835(01)00872-2
2002
Journal Article
The Western Australian experience of the use of en bloc resection of ovarian cancer with concomitant rectosigmoid colectomy
Clayton, RD, Obermair, A, Hammond, IG, Leung, YC and McCartney, AJ (2002). The Western Australian experience of the use of en bloc resection of ovarian cancer with concomitant rectosigmoid colectomy. Gynecologic Oncology, 84 (1), 53-57. doi: 10.1006/gyno.2001.6469
2002
Journal Article
The impact of positive peritoneal washings and serosal and adnexal involvement on survival in patients with stage IIIA uterine cancer
Preyer, O., Obermair, A., Formann, E., Schmid, W., Perrin, L. C., Ward, B. G., Crandon, A. J. and Nicklin, J. L. (2002). The impact of positive peritoneal washings and serosal and adnexal involvement on survival in patients with stage IIIA uterine cancer. Gynecologic Oncology, 86 (3), 269-273. doi: 10.1006/gyno.2002.6744
2002
Journal Article
Expression of MUC1 splice variants in benign and malignant ovarian tumours
Obermair, A., Schmid, B. C., Packer, L. M., Leodolter, S., Birner, P., Ward, B. G., Crandon, A. J., McGuckin, M. A. and Zeillinger, R. (2002). Expression of MUC1 splice variants in benign and malignant ovarian tumours. International Journal of Cancer, 100 (2), 166-171. doi: 10.1002/ijc.10456
2001
Journal Article
Analysis of the human progesterone receptor gene polymorphism progins in Austrian ovarian carcinoma patients
Tong, D, Fabjani, G, Heinze, G, Obermair, A, Leodolter, S and Zeillinger, R (2001). Analysis of the human progesterone receptor gene polymorphism progins in Austrian ovarian carcinoma patients. International Journal of Cancer, 95 (6), 394-397. doi: 10.1002/1097-0215(20011120)95:63.0.CO;2-X
2001
Journal Article
Novel MUCI splice variants are expressed in cervical carcinoma
Schmidt, B. C., Obermair, A., Stimpfl, M., Fasching, B., Preyer, O., Leodolter, S., Crandon, A. J. and Zeillinger, R. (2001). Novel MUCI splice variants are expressed in cervical carcinoma. Gynecologic Oncology, 83 (2), 343-347. doi: 10.1006/gyno.2001.6396
2001
Journal Article
DNA repair-redox enzyme apurinic endonuclease in cervical cancer: Evaluation of redox control of HIF-1 alpha and prognostic significance
Schindl, M, Oberhuber, G, Pichlbauer, EG, Obermair, A, Birner, P and Kelley, MR (2001). DNA repair-redox enzyme apurinic endonuclease in cervical cancer: Evaluation of redox control of HIF-1 alpha and prognostic significance. International Journal of Oncology, 19 (4), 799-802.
2001
Journal Article
The significance of psammoma bodies on cervical cytology smears
Nicklin, James L., Perrin, Lewis, Obermair, Adreas, McConachie, Inta and Cominos, Diane (2001). The significance of psammoma bodies on cervical cytology smears. Gynecologic Oncology, 83 (1), 6-9. doi: 10.1006/gyno.2001.6325
2001
Journal Article
Impact of hemoglobin levels before and during concurrent chemoradiotherapy on the response of treatment in patients with cervical carcinoma - Preliminary results
Obermair, A., Cheuk, R., Horwood, K., Janda, M., Bachtiary, B., Schwanzelberger, B., Stoiber, A., Nicklin, J. L., Perrin, L. C. and Crandon, A. J. (2001). Impact of hemoglobin levels before and during concurrent chemoradiotherapy on the response of treatment in patients with cervical carcinoma - Preliminary results. Cancer, 92 (4), 903-908. doi: 10.1002/1097-0142(20010815)92:43.0.CO;2-2
2001
Journal Article
Overexpression of Id-1 protein is a marker for unfavorable prognosis in early-stage cervical cancer
Schindl, M, Oberhuber, G, Obermair, A, Schoppmann, SF, Karner, B and Birner, P (2001). Overexpression of Id-1 protein is a marker for unfavorable prognosis in early-stage cervical cancer. Cancer Research, 61 (15), 5703-5706.
2001
Journal Article
Prognostic parameters in carcinosarcomas of the uterus: A clinico-pathologic study
Bodner-Adler, B, Bodner, K, Obermair, A, Czerwenka, K, Petru, E, Leodolter, S and Mayerhofer, K (2001). Prognostic parameters in carcinosarcomas of the uterus: A clinico-pathologic study. Anticancer Research, 21 (4B), 3069-3074.
2001
Journal Article
Expression of hypoxia-inducible factor 1 alpha in epithelial ovarian tumors: Its impact on prognosis and on response to chemotherapy
Birner, P, Schindl, M, Obermair, A, Breitenecker, G and Oberhuber, G (2001). Expression of hypoxia-inducible factor 1 alpha in epithelial ovarian tumors: Its impact on prognosis and on response to chemotherapy. Clinical Cancer Research, 7 (6), 1661-1668.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Andreas Obermair is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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feMMe: Uterus-preserving treatment of endometrial cancer
In 2020 we completed the feMMe, phase 2 cliniccal trial which established anticancer activity of levonorgestrel intrauterrine device (LNG-IUD) to treat endometrial cancer. The next two steps towards estabnlioshing this treatment for larger groups of patients include:
1. To determine factors that predict response to LNG-IUD
2. To determine long-term patient outcomes including survival, fertility, and patient needs.
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Improving Quality of Survival for Women with Gynaecological Cancer
- Focus on improving quality of life, health & function during & after gynaecological cancer treatment, with a focus on biomarker research, implementation research and cancer survivorship.
Supervision history
Current supervision
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Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Principal Advisor
Other advisors: Dr Eva Baxter, Dr Zoe West, Professor Andrew Martin
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Master Philosophy
Patterns of care in endometrial cancer management in Queensland: a retrospective analysis.
Principal Advisor
Other advisors: Dr Eva Baxter
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Doctor Philosophy
Diet quality and composition in Australian women with endometrial cancer
Associate Advisor
Other advisors: Professor Monika Janda
Completed supervision
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2014
Doctor Philosophy
Hereditary endometrial cancer: Improving identification and referral of patients with suspected Lynch syndrome
Principal Advisor
Other advisors: Honorary Professor Amanda Spurdle, Associate Professor Lisa Fitzgerald
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2008
Doctor Philosophy
Nutritional status of patients with gynaecological cancer -
Joint Principal Advisor
Other advisors: Emeritus Professor Geoffrey Cleghorn
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Media
Enquiries
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