Overview
Background
Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC Research). He is a Professor of Gynaecological Oncology since 2007, a Senior Medical Officer at Royal Brisbane & Women’s Hospital and a Visiting Medical Officer at St Andrews War Memorial Hospital and Buderim Private Hospital. He holds an Honorary title of Professor at UQ since 2006.
Professor Obermair is an internationally recognised leader in gynaecological oncology research and treatment and has lead the research team at QCGC Research since establishing it in 2003.
Availability
- Professor Andreas Obermair is:
- Available for supervision
Fields of research
Qualifications
- Doctoral Diploma of Medicine, International University Vienna
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
Research interests
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Clinical Trials
Decisions on cancer management ideally are based on the results of high-level evidence, obtained through clinical trials whenever possible. As a principle, a new (proposed better) intervention should be compared to the current standard treatment before being made available generally. Outside a clinical trial new treatments should not become available until evidence has become available to demonstrate superiority over the current standard treatment. Retrospective studies harbour the risk that biases influenced outcomes. At QCGC Research we engage in phase 2 and 3 clinical trials. In large phase trials, patients are allocated randomly to one of two or more interventions in order to minimise the risk of bias. Generally, patients treated within clinical trials have a better outcome compared to patients who are not treated in clinical trials. As the Director of Research Gynaecological Oncology I am currently involved in developing and managing clinical trials in gynaecological cancers.
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Translational Research
The focus of QCGC Research's translational research program is the application of new technology (molecular, biochemical, imaging and surgical) to prevention, detection and therapy for gynaecological cancers.
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Quality of Life Research
Cancer specialists are aware that not only the survival time but also the quality of life is a key factor in cancer treatment. This is especially important when two treatments are equally effective but cause different side-effects. My Quality-of-Life research focuses on ovarian, endometrial, cervical and vulval cancer. I wish to provide the best, most effective and modern treatment to my patients with least possible detriments to quality of life.
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Minimally Invasive Surgery
In Australia, around 30,000 hysterectomies are conducted annually to treat uterine cancer and various benign gynaecological conditions. While open abdominal surgery may be necessary in around 10% of cases, evidence shows that less-invasive approaches, such as total laparoscopic hysterectomy (TLH) can achieve better outcomes for women at a lower overall cost to the health system. Yet, in Queensland, four of ten hysterectomies are still conducted by open abdominal surgery. Our own research has shown that many Australian surgeons are keen to adopt new techniques such as TLH, but that the lack of systematic training and mentoring opportunities is the main impediment to practice-change. Together with gynaecological surgical teams at hospitals and industry support we developed a prototype for system-level transformative practice change in gynaecological surgery.
Research impacts
Professor Obermair is an innovative and skilled gynaecologic oncologist, surgical teacher and consumer advocate. His international leadership and research impact was acknowledged in 2020 by the Australian community, when he was awarded an NHMRC Investigator Fellowship Level 2 (2021-25). The national impact of his research was recognised in 2017, when he was awarded Cancer Australia’s Jeannie Ferris Recognition Award (2017), for outstanding achievements in clinical practice and research. He is deeply engaged in consumer involvement and co-founded and serves on the Board of the Cherish Foundation, a consumer-focussed organisation that funds clinical research in better treatments for women with gynaecological cancers.
Works
Search Professor Andreas Obermair’s works on UQ eSpace
2010
Journal Article
Is surgical literature relevant?
Obermair, Andreas (2010). Is surgical literature relevant?. International Journal of Gynecological Cancer, 20 (8), 1300-1300. doi: 10.1111/IGC.0b013e3181f5110b
2010
Journal Article
Laparoscopy or laparotomy for early endometrial cancer? Authors' reply
Obermair, Andreas, Gebski, Val and Janda, Monika (2010). Laparoscopy or laparotomy for early endometrial cancer? Authors' reply. Lancet Oncology, 11 (11), 1022-1023. doi: 10.1016/S1470-2045(10)70219-9
2010
Journal Article
Evaluation of tumor-free distance and depth of myometrial invasion as prognostic factors for lymph node metastases in endometrial cancer
Kondalsamy-Chennakesavan, Srinivas, van Vugt, Stijn, Sanday, Karen, Nicklin, Jim, Land, Russell, Perrin, Lewis, Crandon, Alex and Obermair, Andreas (2010). Evaluation of tumor-free distance and depth of myometrial invasion as prognostic factors for lymph node metastases in endometrial cancer. International Journal of Gynecological Cancer, 20 (7), 1217-1221. doi: 10.1111/IGC.0b013e3181ef0a31
2010
Journal Article
Expression and in vitro functions of the ghrelin axis in endometrial cancer
Fung, Jenny N. T., Seim, Inge, Wang, Dengfeng, Obermair, Andreas, Chopin, Lisa K. and Chen, Chen (2010). Expression and in vitro functions of the ghrelin axis in endometrial cancer. Hormone and Cancer, 1 (5), 245-255. doi: 10.1007/s12672-010-0047-1
2010
Journal Article
Controversies in the management of endometrial cancer
Hernandez, Enrique, Obermair, Andreas, Hoskins, Paul J,, Magrina, Javier F. and McLellan, Robert (2010). Controversies in the management of endometrial cancer. Obstetrics and Gynecology International, 2010 (Article ID 894587), 1-2. doi: 10.1155/2010/894587
2010
Journal Article
Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): A randomised trial
Janda, Monika, Gebski, Val, Brand, Alison, Hogg, Russel, Jobling, Thomas W., Land, Russel, Manolitsas, Tom, McCartney, Anthony, Nascimento, Marcelo, Neesham, Deborah, Nicklin, James L., Oehler, Martin K., Otton, Geoff, Perrin, Lewis, Salfinger, Stuart, Hammond, Ian, Leung, Yee, Walsh, Tom, Sykes, Peter, Ngan, Hextan, Garrett, Andrea, Laney, Michael, Ng, Tong Yow, Tam, Karfai, Chan, Karen, Wrede, C. David H., Pather, Selvan, Simcock, Bryony, Farrell, Rhonda and Obermair, Andreas (2010). Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): A randomised trial. The Lancet Oncology, 11 (8), 772-780. doi: 10.1016/S1470-2045(10)70145-5
2010
Journal Article
Pretreatment malnutrition and quality of life - association with prolonged length of hospital stay among patients with gynecological cancer: A cohort study
Laky, Brenda, Janda, Monika, Kondalsamy-Chennakesavan, Srinivas, Cleghorn, Geoffrey and Obermair, Andreas (2010). Pretreatment malnutrition and quality of life - association with prolonged length of hospital stay among patients with gynecological cancer: A cohort study. BMC Cancer, 10 (1) 232, 232-1-232-6. doi: 10.1186/1471-2407-10-232
2010
Conference Publication
Improved Short-term and Long-term Quality of Life for Patients with Endometrial Cancer: Quality of Life Results from the LACE Randomized Controlled Trial Comparing Total Laparoscopic Hysterectomy versus Total Abdominal Hysterectomy for Stage I Endometrial Cancer
Obermair, A., Gebski, V., Jobling, T., Land, R., Manolitsas, T., McCartney, A., Nascimento, M., Nicklin, J., Perrin, L. and Janda, M. (2010). Improved Short-term and Long-term Quality of Life for Patients with Endometrial Cancer: Quality of Life Results from the LACE Randomized Controlled Trial Comparing Total Laparoscopic Hysterectomy versus Total Abdominal Hysterectomy for Stage I Endometrial Cancer. _, _, _. Maryland Heights, MO, United States: Academic Press.
2010
Journal Article
Clinical audit in gynecological cancer surgery: Development of a risk scoring system to predict adverse events
Kondalsamy-Chennakesavan, Srinivas, Bouman, Chantal, De Jong, Suzanne, Sanday, Karen, Nicklin, Jim, Land, Russell and Obermair, Andreas (2010). Clinical audit in gynecological cancer surgery: Development of a risk scoring system to predict adverse events. Obstetrical and Gynecological Survey, 65 (2), 93-94. doi: 10.1097/01.ogx.0000368144.18384.fa
2010
Journal Article
Potential hospital cost-savings attributed to improvements in outcomes for colorectal cancer surgery following self-audit
Gordon, Louisa G. and Obermair, Andreas (2010). Potential hospital cost-savings attributed to improvements in outcomes for colorectal cancer surgery following self-audit. BMC Surgery, 10 (4) 4, 1-9. doi: 10.1186/1471-2482-10-4
2010
Conference Publication
Prognostic indicators for recurrent stage I epithelial ovarian cancer
Chetty, N., Van Hoff, J., Kondalsamy-Chennakesavan, S., Obermair, A., Nicklin, J., Perrin, L., Crandon, A., Nascimento, M. and Garrett, A. (2010). Prognostic indicators for recurrent stage I epithelial ovarian cancer. 41st Annual Meeting of the Society of Gynecologic Oncologists, San Francisco, California., 10-17 March 2010. Maryland Heights, MO, U.S.A.: Academic Press. doi: 10.1016/j.ygyno.2009.12.013
2010
Conference Publication
Nomograms to predict five-year freedom from relapse and overall survival after surgery for endometrial cancer
Kondalsamy-Chennakesavan, S, Yu, C., Kattan, M., Van Vugt, S. and Obermair, A. (2010). Nomograms to predict five-year freedom from relapse and overall survival after surgery for endometrial cancer. 41st Annual Meeting of the Society of Gynecologic Oncologists, San Francisco, California., 10-17 March 2010. Maryland Heights, MO, U.S.A.: Academic Press. doi: 10.1016/j.ygyno.2009.12.013
2010
Conference Publication
Evaluation of tumor-free distance and depth of myometrial invasion as prognostic factors in surgically staged adenocarcinoma of the uterus
Van Vugt, S., Jackson, D., Sanday, K., Obermair, A. and Kondalsamy-Chennakesavan, S. (2010). Evaluation of tumor-free distance and depth of myometrial invasion as prognostic factors in surgically staged adenocarcinoma of the uterus. 41st Annual Meeting of the Society of Gynecologic Oncologists, San Francisco, California., 10-17 March 2010. Maryland Heights, MO, U.S.A.: Academic Press. doi: 10.1016/j.ygyno.2009.12.013
2009
Journal Article
Clinical audit in gynecological cancer surgery: Development of a risk scoring system to predict adverse events
Kondalsamy-Chennakesavan, Srinivas, Bouman, Chantal, De Jong, Suzanne, Sanday, Karen, Nicklin, Jim, Land, Russell and Obermair, Andreas (2009). Clinical audit in gynecological cancer surgery: Development of a risk scoring system to predict adverse events. Gynecologic Oncology, 115 (3), 329-333. doi: 10.1016/j.ygyno.2009.08.004
2009
Journal Article
Depression, anxiety and body image after treatment for invasive stage one epithelial ovarian cancer
Bisseling, Karin C. H. M., Kondalsamy-Chennakesavan, Srinivas, Bekkers, Ruud L. M., Janda, Monika and Obermair, Andreas (2009). Depression, anxiety and body image after treatment for invasive stage one epithelial ovarian cancer. Australian & New Zealand Journal of Obstetrics & Gynaecology, 49 (6), 660-666. doi: 10.1111/j.1479-828X.2009.01074.x
2009
Journal Article
Advanced cytoreductive surgery: Asia Pacific perspective
Crandon, Alexander J. and Obermair, Andreas (2009). Advanced cytoreductive surgery: Asia Pacific perspective. Gynecologic Oncology, 114 (2), S15-S21. doi: 10.1016/j.ygyno.2008.11.007
2009
Conference Publication
Sentinel lymph node biopsy in patients with gynecologic cancers: Expert panel statement from the International Sentinel Node Society Meeting, February 21, 2008
Levenback, Charles F., van der Zee, Ate G. J., Rob, Lukas, Plante, Marie, Covens, Al, Schneider, Achim, Coleman, Robert, Solima, Eugenio, Hertel, Hermann, Barranger, Emmanuel, Obermair, Andreas and Roy, Michel (2009). Sentinel lymph node biopsy in patients with gynecologic cancers: Expert panel statement from the International Sentinel Node Society Meeting, February 21, 2008. United States: Elsevier. doi: 10.1016/j.ygyno.2009.03.035
2009
Journal Article
Survey of surgical skills of RANZCOG trainees
Obermair, A, Tang, A, Charters, D, Weaver, E and Hammond, I (2009). Survey of surgical skills of RANZCOG trainees. Australian and New Zealand Journal of Obstetrics and Gynaecology, 49 (1), 84-92. doi: 10.1111/j.1479-828X.2008.00935.x
2009
Conference Publication
Clinical audit in gynecological cancer surgery: Development of a risk scoring system to predict adverse events
Kondalsamy-Chennakesavan, Srinivas, Bouman, Chantal, De Jong, Suzanne, Sanday, Karen, Nicklin, Jim, Land, Russell and Obermair, Andreas (2009). Clinical audit in gynecological cancer surgery: Development of a risk scoring system to predict adverse events. Annual Scientific Meeting of the Australian and New Zealand Gynaecological Oncology Group/Australian Society of Gynaecological Oncology, Noosa, Australia, 2 April 2009. Maryland Heights, MO, United States: Academic Press. doi: 10.1016/j.ygyno.2009.08.004
2008
Journal Article
Lynch syndrome in women less than 50 years of age with endometrial cancer
Walsh, Michael D., Young, Joanne, Spurdle, Amanda and Obermair, Andreas (2008). Lynch syndrome in women less than 50 years of age with endometrial cancer. Obstetrics and Gynecology, 112 (4), 943-943. doi: 10.1097/AOG.0b013e3181893013
Funding
Current funding
Past funding
Supervision
Availability
- Professor Andreas Obermair is:
- Available for supervision
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Available projects
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feMMe: Uterus-preserving treatment of endometrial cancer
In 2020 we completed the feMMe, phase 2 cliniccal trial which established anticancer activity of levonorgestrel intrauterrine device (LNG-IUD) to treat endometrial cancer. The next two steps towards estabnlioshing this treatment for larger groups of patients include:
1. To determine factors that predict response to LNG-IUD
2. To determine long-term patient outcomes including survival, fertility, and patient needs.
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Improving Quality of Survival for Women with Gynaecological Cancer
- Focus on improving quality of life, health & function during & after gynaecological cancer treatment, with a focus on biomarker research, implementation research and cancer survivorship.
Supervision history
Current supervision
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Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Principal Advisor
Other advisors: Dr Eva Baxter, Dr Zoe West, Professor Andrew Martin
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Master Philosophy
Patterns of care in endometrial cancer management in Queensland: a retrospective analysis.
Principal Advisor
Other advisors: Dr Eva Baxter
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Doctor Philosophy
Diet quality and composition in Australian women with endometrial cancer
Associate Advisor
Other advisors: Professor Monika Janda
Completed supervision
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2014
Doctor Philosophy
Hereditary endometrial cancer: Improving identification and referral of patients with suspected Lynch syndrome
Principal Advisor
Other advisors: Honorary Professor Amanda Spurdle, Associate Professor Lisa Fitzgerald
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2008
Doctor Philosophy
Nutritional status of patients with gynaecological cancer -
Joint Principal Advisor
Other advisors: Emeritus Professor Geoffrey Cleghorn
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Media
Enquiries
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