Overview
Background
Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC Research). He is a Professor of Gynaecological Oncology since 2007, a Senior Medical Officer at Royal Brisbane & Women’s Hospital and a Visiting Medical Officer at St Andrews War Memorial Hospital and Buderim Private Hospital. He holds an Honorary title of Professor at UQ since 2006.
Professor Obermair is an internationally recognised leader in gynaecological oncology research and treatment and has lead the research team at QCGC Research since establishing it in 2003.
Availability
- Professor Andreas Obermair is:
- Available for supervision
Fields of research
Qualifications
- Doctoral Diploma of Medicine, International University Vienna
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
Research interests
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Clinical Trials
Decisions on cancer management ideally are based on the results of high-level evidence, obtained through clinical trials whenever possible. As a principle, a new (proposed better) intervention should be compared to the current standard treatment before being made available generally. Outside a clinical trial new treatments should not become available until evidence has become available to demonstrate superiority over the current standard treatment. Retrospective studies harbour the risk that biases influenced outcomes. At QCGC Research we engage in phase 2 and 3 clinical trials. In large phase trials, patients are allocated randomly to one of two or more interventions in order to minimise the risk of bias. Generally, patients treated within clinical trials have a better outcome compared to patients who are not treated in clinical trials. As the Director of Research Gynaecological Oncology I am currently involved in developing and managing clinical trials in gynaecological cancers.
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Translational Research
The focus of QCGC Research's translational research program is the application of new technology (molecular, biochemical, imaging and surgical) to prevention, detection and therapy for gynaecological cancers.
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Quality of Life Research
Cancer specialists are aware that not only the survival time but also the quality of life is a key factor in cancer treatment. This is especially important when two treatments are equally effective but cause different side-effects. My Quality-of-Life research focuses on ovarian, endometrial, cervical and vulval cancer. I wish to provide the best, most effective and modern treatment to my patients with least possible detriments to quality of life.
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Minimally Invasive Surgery
In Australia, around 30,000 hysterectomies are conducted annually to treat uterine cancer and various benign gynaecological conditions. While open abdominal surgery may be necessary in around 10% of cases, evidence shows that less-invasive approaches, such as total laparoscopic hysterectomy (TLH) can achieve better outcomes for women at a lower overall cost to the health system. Yet, in Queensland, four of ten hysterectomies are still conducted by open abdominal surgery. Our own research has shown that many Australian surgeons are keen to adopt new techniques such as TLH, but that the lack of systematic training and mentoring opportunities is the main impediment to practice-change. Together with gynaecological surgical teams at hospitals and industry support we developed a prototype for system-level transformative practice change in gynaecological surgery.
Research impacts
Professor Obermair is an innovative and skilled gynaecologic oncologist, surgical teacher and consumer advocate. His international leadership and research impact was acknowledged in 2020 by the Australian community, when he was awarded an NHMRC Investigator Fellowship Level 2 (2021-25). The national impact of his research was recognised in 2017, when he was awarded Cancer Australia’s Jeannie Ferris Recognition Award (2017), for outstanding achievements in clinical practice and research. He is deeply engaged in consumer involvement and co-founded and serves on the Board of the Cherish Foundation, a consumer-focussed organisation that funds clinical research in better treatments for women with gynaecological cancers.
Works
Search Professor Andreas Obermair’s works on UQ eSpace
1994
Conference Publication
Delayed diagnosis of advanced endometrial carcinoma
Buxbaum, P, Obermair, A, Schreinerfrech, I, Kurz, C, Vavra, N and Sevelda, P (1994). Delayed diagnosis of advanced endometrial carcinoma. Annual Meeting of the Osterreichischen-Gesellschaft-fur-Gynakologie-und-Geburtshilfe, Bregenz Austria, Jun, 1994. BASEL: KARGER. doi: 10.1159/000272749
1994
Journal Article
Blood-Vessel Invasion in Breast-Cancer - a Comparison of Hematoxylin-Eosin Staining and Immunohistochemical Staining for Factor-Viii Antigen for Their Prognostic Value Concerning Tumor Recurrence
Obermair, A, Czerwenka, K, Kurz, C, Kaider, A and Sevelda, P (1994). Blood-Vessel Invasion in Breast-Cancer - a Comparison of Hematoxylin-Eosin Staining and Immunohistochemical Staining for Factor-Viii Antigen for Their Prognostic Value Concerning Tumor Recurrence. Deutsche Medizinische Wochenschrift, 119 (44), 1491-1496. doi: 10.1055/s-2008-1058863
1994
Journal Article
Tumoral Microvessel Density in Breast-Cancer and its Influence On Recurrence-Free Survival
Obermair, A, Czerwenka, K, Kurz, C, Kaider, A and Sevelda, P (1994). Tumoral Microvessel Density in Breast-Cancer and its Influence On Recurrence-Free Survival. Chirurg, 65 (7), 611-615.
1994
Journal Article
Tumoral vascular density in breast tumors and their effect on recurrence-free survival Tumorale Gefässdichte bei Mammatumoren und ihr Einfluss auf das rezidivfreie Uberleben
Obermair, A., Czerwenka, K., Kurz, C., Kaider, A. and Sevelda, P. (1994). Tumoral vascular density in breast tumors and their effect on recurrence-free survival Tumorale Gefässdichte bei Mammatumoren und ihr Einfluss auf das rezidivfreie Uberleben. Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen, 65 (7), 611-615.
1994
Journal Article
Ranking of the factor 'vascular invasion' for the prognosis of carcinoma of the breast DIE WERTIGKEIT DES FAKTORS 'GEFASSINVASION' FUR DIE PROGNOSE DES MAMMAKARZINOMS
Kurz, C., Obermair, A., Nagele, F., Czerwenka, K., Schemper, M., Kubista, E. and Sevelda, P. (1994). Ranking of the factor 'vascular invasion' for the prognosis of carcinoma of the breast DIE WERTIGKEIT DES FAKTORS 'GEFASSINVASION' FUR DIE PROGNOSE DES MAMMAKARZINOMS. Geburtshilfe und Frauenheilkunde, 54 (5), 295-299.
1994
Journal Article
Ranking of the Factor Vascular Invasion for the Prognosis of Carcinoma of the Breast
Kurz, C, Obermair, A, Nagele, F, Czerwenka, K, Schemper, M, Kubista, E and Sevelda, P (1994). Ranking of the Factor Vascular Invasion for the Prognosis of Carcinoma of the Breast. Geburtshilfe Und Frauenheilkunde, 54 (5), 295-299. doi: 10.1055/s-2007-1022843
1994
Journal Article
Thrombosis with Paclitaxel
Sevelda, P, Mayerhofer, K, Obermair, A, Stolzlechner, J and Kurz, C (1994). Thrombosis with Paclitaxel. Lancet, 343 (8899), 727-727. doi: 10.1016/S0140-6736(94)91602-0
1994
Journal Article
Influence of Tumoral Microvessel Density On the Recurrence-Free Survival in Human Breast-Cancer - Preliminary-Results
Obermair, A, Czerwenka, K, Kurz, C, Buxbaum, P, Schemper, M and Sevelda, P (1994). Influence of Tumoral Microvessel Density On the Recurrence-Free Survival in Human Breast-Cancer - Preliminary-Results. Onkologie, 17 (1), 44-49. doi: 10.1159/000218380
1994
Journal Article
Blood vessel invasion in breast cancer. A comparison of haematoxylin-eosin staining and immunohistochemical staining for factor VIII antigen for their prognostic value concerning tumour recurrence TUMORGEFASSINVASION BEIM MAMMAKARZINOM. HAMATOXYLIN-EOSIN- VERSUS IMMUNHISTOCHEMISCHE FARBUNG GEGEN FAKTOR-VIII-ANTIGEN
Obermair, A., Czerwenka, K., Kurz, C., Kaider, A. and Sevelda, P. (1994). Blood vessel invasion in breast cancer. A comparison of haematoxylin-eosin staining and immunohistochemical staining for factor VIII antigen for their prognostic value concerning tumour recurrence TUMORGEFASSINVASION BEIM MAMMAKARZINOM. HAMATOXYLIN-EOSIN- VERSUS IMMUNHISTOCHEMISCHE FARBUNG GEGEN FAKTOR-VIII-ANTIGEN. Deutsche Medizinische Wochenschrift, 119 (44), 1491-1496.
1993
Journal Article
Vessel Invasion Predicts Early Recurrence in Breast-Cancer - Preliminary-Results
Obermair, A, Czerwenka, K, Kurz, C, Schemper, M and Sevelda, P (1993). Vessel Invasion Predicts Early Recurrence in Breast-Cancer - Preliminary-Results. Onkologie, 16 (6), 434-439. doi: 10.1159/000218302
1993
Journal Article
Beeinflusst Adipositas das rezidivfreie Intervall beim Mammakarzinom?
Kurz, C., Obermair, A., Schemper, W., Kubista, E. and Sevelda, P. (1993). Beeinflusst Adipositas das rezidivfreie Intervall beim Mammakarzinom?. Gynäkologisch-geburtshilfliche Rundschau, 33 Suppl 1 (1), 305-307. doi: 10.1159/000272276
1993
Conference Publication
Hormone-Therapy Vs Chemotherapy Plus Hormone-Therapy in Patients with Hormone Receptor-Positive Breast-Cancer in Stage-I and Stage-II
Sevelda, P, Kurz, C, Obermair, A, Kubista, E and Salzer, H (1993). Hormone-Therapy Vs Chemotherapy Plus Hormone-Therapy in Patients with Hormone Receptor-Positive Breast-Cancer in Stage-I and Stage-II. 49th Meeting of the Deutschen-Gesellschaft-fur-Gynakologie-und-Geburtshilfe, Berlin Germany, Sep 08-12, 1992. NEW YORK: SPRINGER VERLAG. doi: 10.1007/BF02266224
1993
Journal Article
The importance of platinum dose intensity in treatment of epithelial ovarian cancer DIE BEDEUTUNG DER PLATINDOSISINTENSITAT IN DER BEHANDLUNG DES EPITHELIALEN OVARIALKARZINOMS
Sevelda, P., Kurz, C., Obermair, A., Vavra, N., Breitenecker, G., Czerwenka, K., Dittrich, C. and Salzer, H. (1993). The importance of platinum dose intensity in treatment of epithelial ovarian cancer DIE BEDEUTUNG DER PLATINDOSISINTENSITAT IN DER BEHANDLUNG DES EPITHELIALEN OVARIALKARZINOMS. Wiener Klinische Wochenschrift, 105 (24), 732-736.
1993
Journal Article
L-Carnitine-Betamethasone Combination Vs Betamethasone for Prevention of Respiratory-Distress Syndrome
Kurz, C, Arbeiter, K, Obermair, A, Salzer, H, Salzer, HR and Lohninger, A (1993). L-Carnitine-Betamethasone Combination Vs Betamethasone for Prevention of Respiratory-Distress Syndrome. Zeitschrift Fur Geburtshilfe Und Perinatologie, 197 (5), 215-219.
1993
Journal Article
The Importance of Platinum Dose Intensity in Treatment of Epithelial Ovarian-Cancer
Sevelda, P, Kurz, C, Obermair, A, Vavra, N, Breitenecker, G, Czerwenka, K, Dittrich, C and Salzer, H (1993). The Importance of Platinum Dose Intensity in Treatment of Epithelial Ovarian-Cancer. Wiener Klinische Wochenschrift, 105 (24), 732-736.
1992
Journal Article
Die bedeutung der primär vollständigen tumorentfernung für den weiteren krankheits- verlauf beim mammakarzinom
Kurz, Christine, Scholten, Ch, Kreiner, M., Obermair, A., Seifert, M., Cerwenka, K., Kubista, E. and Sevelda, P. (1992). Die bedeutung der primär vollständigen tumorentfernung für den weiteren krankheits- verlauf beim mammakarzinom. Gynakologisch-geburtshilfliche Rundschau, 32 (1), 108-109. doi: 10.1159/000271959
1991
Journal Article
A Concept for the Implementation of a Personal-Computer Based Data-Bank System in Gynecological Oncology for the Follow-Up of Patients
Obermair, A (1991). A Concept for the Implementation of a Personal-Computer Based Data-Bank System in Gynecological Oncology for the Follow-Up of Patients. Wiener Klinische Wochenschrift, 103 (12), 371-373.
1991
Journal Article
Möglichkeiten und ziele in der tumornachsorge beim mammakarzinom
Seifert, M., Adler, A., Obermair, A., Hartmann, B., Denison, U., Kubista, E. and Sevelda, P. (1991). Möglichkeiten und ziele in der tumornachsorge beim mammakarzinom. Gynakologisch-geburtshilfliche Rundschau, 31 (2), 309-311. doi: 10.1159/000271776
1991
Journal Article
Vaginosonographical Observation of Uterine Contractions During Embryo Transfer and its Relevance with Respect of Treatment Success
Aichberger, L, Boldizsar, A, Herczeg, C, Obermair, A, Plockinger, B, Strohmer, H, Vatanparast, Z, Kemeter, P and Feichtinger, W (1991). Vaginosonographical Observation of Uterine Contractions During Embryo Transfer and its Relevance with Respect of Treatment Success. Geburtshilfe Und Frauenheilkunde, 51 (1), 27-30. doi: 10.1055/s-2008-1026327
1991
Journal Article
Development of gynecologic-oncologic patient data records for after care Die Erstellung einer gynäkologisch-onkologischen Patientendatei für die Nachsorge
Obermair, A. (1991). Development of gynecologic-oncologic patient data records for after care Die Erstellung einer gynäkologisch-onkologischen Patientendatei für die Nachsorge. Wiener Klinische Wochenschrift, 103 (12), 371-373.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Andreas Obermair is:
- Available for supervision
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Available projects
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feMMe: Uterus-preserving treatment of endometrial cancer
In 2020 we completed the feMMe, phase 2 cliniccal trial which established anticancer activity of levonorgestrel intrauterrine device (LNG-IUD) to treat endometrial cancer. The next two steps towards estabnlioshing this treatment for larger groups of patients include:
1. To determine factors that predict response to LNG-IUD
2. To determine long-term patient outcomes including survival, fertility, and patient needs.
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Improving Quality of Survival for Women with Gynaecological Cancer
- Focus on improving quality of life, health & function during & after gynaecological cancer treatment, with a focus on biomarker research, implementation research and cancer survivorship.
Supervision history
Current supervision
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Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Principal Advisor
Other advisors: Dr Eva Baxter, Dr Zoe West, Professor Andrew Martin
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Master Philosophy
Patterns of care in endometrial cancer management in Queensland: a retrospective analysis.
Principal Advisor
Other advisors: Dr Eva Baxter
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Doctor Philosophy
Diet quality and composition in Australian women with endometrial cancer
Associate Advisor
Other advisors: Professor Monika Janda
Completed supervision
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2014
Doctor Philosophy
Hereditary endometrial cancer: Improving identification and referral of patients with suspected Lynch syndrome
Principal Advisor
Other advisors: Honorary Professor Amanda Spurdle, Associate Professor Lisa Fitzgerald
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2008
Doctor Philosophy
Nutritional status of patients with gynaecological cancer -
Joint Principal Advisor
Other advisors: Emeritus Professor Geoffrey Cleghorn
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Media
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