Overview
Background
Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC Research). He is a Professor of Gynaecological Oncology since 2007, a Senior Medical Officer at Royal Brisbane & Women’s Hospital and a Visiting Medical Officer at St Andrews War Memorial Hospital and Buderim Private Hospital. He holds an Honorary title of Professor at UQ since 2006.
Professor Obermair is an internationally recognised leader in gynaecological oncology research and treatment and has lead the research team at QCGC Research since establishing it in 2003.
Availability
- Professor Andreas Obermair is:
- Available for supervision
Fields of research
Qualifications
- Doctoral Diploma of Medicine, International University Vienna
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
Research interests
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Clinical Trials
Decisions on cancer management ideally are based on the results of high-level evidence, obtained through clinical trials whenever possible. As a principle, a new (proposed better) intervention should be compared to the current standard treatment before being made available generally. Outside a clinical trial new treatments should not become available until evidence has become available to demonstrate superiority over the current standard treatment. Retrospective studies harbour the risk that biases influenced outcomes. At QCGC Research we engage in phase 2 and 3 clinical trials. In large phase trials, patients are allocated randomly to one of two or more interventions in order to minimise the risk of bias. Generally, patients treated within clinical trials have a better outcome compared to patients who are not treated in clinical trials. As the Director of Research Gynaecological Oncology I am currently involved in developing and managing clinical trials in gynaecological cancers.
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Translational Research
The focus of QCGC Research's translational research program is the application of new technology (molecular, biochemical, imaging and surgical) to prevention, detection and therapy for gynaecological cancers.
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Quality of Life Research
Cancer specialists are aware that not only the survival time but also the quality of life is a key factor in cancer treatment. This is especially important when two treatments are equally effective but cause different side-effects. My Quality-of-Life research focuses on ovarian, endometrial, cervical and vulval cancer. I wish to provide the best, most effective and modern treatment to my patients with least possible detriments to quality of life.
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Minimally Invasive Surgery
In Australia, around 30,000 hysterectomies are conducted annually to treat uterine cancer and various benign gynaecological conditions. While open abdominal surgery may be necessary in around 10% of cases, evidence shows that less-invasive approaches, such as total laparoscopic hysterectomy (TLH) can achieve better outcomes for women at a lower overall cost to the health system. Yet, in Queensland, four of ten hysterectomies are still conducted by open abdominal surgery. Our own research has shown that many Australian surgeons are keen to adopt new techniques such as TLH, but that the lack of systematic training and mentoring opportunities is the main impediment to practice-change. Together with gynaecological surgical teams at hospitals and industry support we developed a prototype for system-level transformative practice change in gynaecological surgery.
Research impacts
Professor Obermair is an innovative and skilled gynaecologic oncologist, surgical teacher and consumer advocate. His international leadership and research impact was acknowledged in 2020 by the Australian community, when he was awarded an NHMRC Investigator Fellowship Level 2 (2021-25). The national impact of his research was recognised in 2017, when he was awarded Cancer Australia’s Jeannie Ferris Recognition Award (2017), for outstanding achievements in clinical practice and research. He is deeply engaged in consumer involvement and co-founded and serves on the Board of the Cherish Foundation, a consumer-focussed organisation that funds clinical research in better treatments for women with gynaecological cancers.
Works
Search Professor Andreas Obermair’s works on UQ eSpace
2000
Journal Article
Significance of pretreatment serum hemoglobin and survival in epithelial ovarian cancer
Obermair, A, Petru, E, Windbichler, G, Peters-Engl, C, Graf, AH, Stummvoll, W, Kaider, A, Kurschel, S, Kolbl, H and Sevelda, P (2000). Significance of pretreatment serum hemoglobin and survival in epithelial ovarian cancer. Oncology Reports, 7 (3), 639-644.
2000
Journal Article
Does hysteroscopy facilitate tumor cell dissemination?
Obermair, Andreas, Geramou, Magda, Gucer, Fatih, Denison, Ursula, Graf, Anton H., Kapshammer, Elisabeth, Neunteufel, Walter, Frech, Inge, Kaider, Alexandra and Kainz, Christian (2000). Does hysteroscopy facilitate tumor cell dissemination?. Cancer, 88 (1), 139-143. doi: 10.1002/(sici)1097-0142(20000101)88:13.3.co;2-l
2000
Journal Article
Does hysteroscopy facilitate tumor cell dissemination? Incidence of peritoneal cytology from patients wild early stage endometrial carcinoma following dilatation and curettage (D & C) versus hysteroscopy and D & C
Obermair, A, Geramou, M, Gucer, F, Denison, U, Graf, AH, Kapshammer, E, Neunteufel, W, Frech, I, Kaider, A, Kainz, C and Austrian Gynecol Oncol Study Grp (2000). Does hysteroscopy facilitate tumor cell dissemination? Incidence of peritoneal cytology from patients wild early stage endometrial carcinoma following dilatation and curettage (D & C) versus hysteroscopy and D & C. Cancer, 88 (1), 139-143. doi: 10.1002/(SICI)1097-0142(20000101)88:13.0.CO;2-U
2000
Journal Article
Vascular endothelial growth factor serum levels in pregnancy and preeclampsia
Hefler, L, Obermair, A, Husslein, P, Kainz, C and Tempfer, C (2000). Vascular endothelial growth factor serum levels in pregnancy and preeclampsia. Acta Obstetricia Et Gynecologica Scandinavica, 79 (1), 77-78. doi: 10.1034/j.1600-0412.2000.079001077.x
1999
Journal Article
Tumor angiogenesis and its relation to prognosis in epithelial ovarian cancer
Obermair, A., Preyer, O. and Leodolter, S. (1999). Tumor angiogenesis and its relation to prognosis in epithelial ovarian cancer. CME Journal of Gynecologic Oncology, 4 (2), 169-177.
1999
Conference Publication
Multiple myeloma (MM) with deletion of 13q13 is characterized by increased bone marrow (BM) neovascularization - Implications for treatment of high-risk disease.
Drach, J, Ackermann, J, Obermair, A, Chott, A, Fuchs, K, Schreiber, S, Konigsberg, R, Kaufmann, H, Urbauer, E, Geissler, K, Gisslinger, H and Huber, H (1999). Multiple myeloma (MM) with deletion of 13q13 is characterized by increased bone marrow (BM) neovascularization - Implications for treatment of high-risk disease.. WASHINGTON: AMER SOC HEMATOLOGY.
1999
Journal Article
CA 125 regression after two completed cycles of chemotherapy: lack of prediction for long-term survival in patients with advanced ovarian cancer
Peters-Engl, C., Obermair, A., Heinzl, H., Buxbaum, P., Sevelda, P. and Medl, M. (1999). CA 125 regression after two completed cycles of chemotherapy: lack of prediction for long-term survival in patients with advanced ovarian cancer. British Journal of Cancer, 81 (4), 662-666. doi: 10.1038/sj.bjc.6690744
1999
Journal Article
Expression of mucins and cytokeratins in ovarian cancer cell lines
Stimpfl, M, Schmid, BC, Schiebel, I, Tong, D, Leodolter, S, Obermair, A and Zeillinger, R (1999). Expression of mucins and cytokeratins in ovarian cancer cell lines. Cancer Letters, 145 (1-2), 133-141. doi: 10.1016/S0304-3835(99)00246-3
1999
Journal Article
Serum concentrations of vascular endothelial growth factor in vulvar cancer
Hefler, L, Tempfer, C, Obermair, A, Frischmuth, K, Sliutz, G, Reinthaller, A, Leodolter, S and Kainz, C (1999). Serum concentrations of vascular endothelial growth factor in vulvar cancer. Clinical Cancer Research, 5 (10), 2806-2809.
1999
Conference Publication
MUC1 mucin for the detection of epithelial-derived ovarian cancer cells in peripheral blood
Obermair, A, Stimpfl, M, Schmid, B, Tong, D, Schiebel, I, Leodolter, S and Zeillinger, R (1999). MUC1 mucin for the detection of epithelial-derived ovarian cancer cells in peripheral blood. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/S0959-8049(99)80808-9
1999
Conference Publication
Prognostic impact of tumor anemia in early-stage epithelial ovarian cancer
Obermair, A, Petru, E, Windbichler, G, Peters-Engl, C, Graf, AH, Stummvoll, W, Kaider, A, Kurschel, S, Kolbl, H and Sevelda, P (1999). Prognostic impact of tumor anemia in early-stage epithelial ovarian cancer. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/S0959-8049(99)81333-1
1999
Journal Article
Endometrial cancer: accuracy of the finding of a well differentiated tumor at dilatation and curettage compared to the findings at subsequent hysterectomy
Obermair, A, Geramou, M, Gucer, F, Denison, U, Graf, AH, Kapshammer, E, Medl, M, Rosen, A, Wierrani, F, Neunteufel, W, Frech, I, Speiser, P, Kainz, C, Breitenecker, G and Austrian Gynecologic Oncology Sty (1999). Endometrial cancer: accuracy of the finding of a well differentiated tumor at dilatation and curettage compared to the findings at subsequent hysterectomy. International Journal of Gynecological Cancer, 9 (5), 383-386. doi: 10.1046/j.1525-1438.1999.99050.x
1999
Journal Article
Vascular endothelial growth factor and its receptors in male fertility
Obermair, A, Obruca, A, Pohl, M, Kaider, A, Vales, A, Leodolter, S, Wojta, J and Feichtinger, W (1999). Vascular endothelial growth factor and its receptors in male fertility. Fertility and Sterility, 72 (2), 269-275. doi: 10.1016/S0015-0282(99)00234-4
1999
Journal Article
Correlation of the serum concentration of vascular endothelial growth factor (VEGF) and hemoglobin levels in patients with epithelial ovarian cancer
Obermair, A, Hefler, L, Nather, A, Preyer, O and Kaider, A (1999). Correlation of the serum concentration of vascular endothelial growth factor (VEGF) and hemoglobin levels in patients with epithelial ovarian cancer. Annals of Oncology, 10 (8), 998-998. doi: 10.1023/A:1008309309456
1999
Journal Article
Leiomyosarcoma of the uterus: A clinicopathologic multicenter study of 71 cases
Mayerhofer, K, Obermair, A, Windbichler, G, Petru, E, Kaider, A, Hefler, L, Czerwenka, K, Leodolter, S and Kainz, C (1999). Leiomyosarcoma of the uterus: A clinicopathologic multicenter study of 71 cases. Gynecologic Oncology, 74 (2), 196-201. doi: 10.1006/gyno.1999.5436
1999
Journal Article
Prognostic significance of tumor angiogenesis in primary fallopian tube cancer
Bancher-Todesca, D, Rosen, A, Graf, A, Wasicky, R, Hohlagschwandtner, M, Rebhandl, W, Heinze, G, Breitenecker, G, Gitsch, G and Obermair, A (1999). Prognostic significance of tumor angiogenesis in primary fallopian tube cancer. Cancer Letters, 141 (1-2), 179-186. doi: 10.1016/S0304-3835(99)00104-4
1999
Journal Article
Serum concentrations of endostatin in patients with vulvar cancer
Hefler, L, Tempfer, C, Kainz, C and Obermair, A (1999). Serum concentrations of endostatin in patients with vulvar cancer. Gynecologic Oncology, 74 (1), 151-152. doi: 10.1006/gyno.1999.5496
1999
Journal Article
Serum concentrations of squamous cell carcinoma antigen in patients with vulvar intraepithelial neoplasia and vulvar cancer
Hefler, L, Obermair, A, Tempfer, C, van Houte, M, Maenner, G, Reinthaller, A, Leodolter, S and Kainz, C (1999). Serum concentrations of squamous cell carcinoma antigen in patients with vulvar intraepithelial neoplasia and vulvar cancer. International Journal of Cancer, 84 (3), 299-303. doi: 10.1002/(SICI)1097-0215(19990621)84:33.0.CO;2-K
1999
Journal Article
Impact of angionesis in gynecology and obstetrics Angiogenese in gynakologie und geburtshilfe
Obermair, Andreas, Preyer, Oliver and Leodolter, Sepp (1999). Impact of angionesis in gynecology and obstetrics Angiogenese in gynakologie und geburtshilfe. Wiener Klinische Wochenschrift, 111 (7), 262-277.
1999
Journal Article
Impact of angiogenesis in gynecology and obstetrics
Obermair, A, Preyer, O and Leodolter, S (1999). Impact of angiogenesis in gynecology and obstetrics. Wiener Klinische Wochenschrift, 111 (7), 262-277.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Andreas Obermair is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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feMMe: Uterus-preserving treatment of endometrial cancer
In 2020 we completed the feMMe, phase 2 cliniccal trial which established anticancer activity of levonorgestrel intrauterrine device (LNG-IUD) to treat endometrial cancer. The next two steps towards estabnlioshing this treatment for larger groups of patients include:
1. To determine factors that predict response to LNG-IUD
2. To determine long-term patient outcomes including survival, fertility, and patient needs.
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Improving Quality of Survival for Women with Gynaecological Cancer
- Focus on improving quality of life, health & function during & after gynaecological cancer treatment, with a focus on biomarker research, implementation research and cancer survivorship.
Supervision history
Current supervision
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Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Principal Advisor
Other advisors: Dr Eva Baxter, Dr Zoe West, Professor Andrew Martin
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Master Philosophy
Patterns of care in endometrial cancer management in Queensland: a retrospective analysis.
Principal Advisor
Other advisors: Dr Eva Baxter
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Doctor Philosophy
Diet quality and composition in Australian women with endometrial cancer
Associate Advisor
Other advisors: Professor Monika Janda
Completed supervision
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2014
Doctor Philosophy
Hereditary endometrial cancer: Improving identification and referral of patients with suspected Lynch syndrome
Principal Advisor
Other advisors: Honorary Professor Amanda Spurdle, Associate Professor Lisa Fitzgerald
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2008
Doctor Philosophy
Nutritional status of patients with gynaecological cancer -
Joint Principal Advisor
Other advisors: Emeritus Professor Geoffrey Cleghorn
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Media
Enquiries
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