Overview
Background
Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC Research). He is a Professor of Gynaecological Oncology since 2007, a Senior Medical Officer at Royal Brisbane & Women’s Hospital and a Visiting Medical Officer at St Andrews War Memorial Hospital and Buderim Private Hospital. He holds an Honorary title of Professor at UQ since 2006.
Professor Obermair is an internationally recognised leader in gynaecological oncology research and treatment and has lead the research team at QCGC Research since establishing it in 2003.
Availability
- Professor Andreas Obermair is:
- Available for supervision
Fields of research
Qualifications
- Doctoral Diploma of Medicine, International University Vienna
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
Research interests
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Clinical Trials
Decisions on cancer management ideally are based on the results of high-level evidence, obtained through clinical trials whenever possible. As a principle, a new (proposed better) intervention should be compared to the current standard treatment before being made available generally. Outside a clinical trial new treatments should not become available until evidence has become available to demonstrate superiority over the current standard treatment. Retrospective studies harbour the risk that biases influenced outcomes. At QCGC Research we engage in phase 2 and 3 clinical trials. In large phase trials, patients are allocated randomly to one of two or more interventions in order to minimise the risk of bias. Generally, patients treated within clinical trials have a better outcome compared to patients who are not treated in clinical trials. As the Director of Research Gynaecological Oncology I am currently involved in developing and managing clinical trials in gynaecological cancers.
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Translational Research
The focus of QCGC Research's translational research program is the application of new technology (molecular, biochemical, imaging and surgical) to prevention, detection and therapy for gynaecological cancers.
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Quality of Life Research
Cancer specialists are aware that not only the survival time but also the quality of life is a key factor in cancer treatment. This is especially important when two treatments are equally effective but cause different side-effects. My Quality-of-Life research focuses on ovarian, endometrial, cervical and vulval cancer. I wish to provide the best, most effective and modern treatment to my patients with least possible detriments to quality of life.
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Minimally Invasive Surgery
In Australia, around 30,000 hysterectomies are conducted annually to treat uterine cancer and various benign gynaecological conditions. While open abdominal surgery may be necessary in around 10% of cases, evidence shows that less-invasive approaches, such as total laparoscopic hysterectomy (TLH) can achieve better outcomes for women at a lower overall cost to the health system. Yet, in Queensland, four of ten hysterectomies are still conducted by open abdominal surgery. Our own research has shown that many Australian surgeons are keen to adopt new techniques such as TLH, but that the lack of systematic training and mentoring opportunities is the main impediment to practice-change. Together with gynaecological surgical teams at hospitals and industry support we developed a prototype for system-level transformative practice change in gynaecological surgery.
Research impacts
Professor Obermair is an innovative and skilled gynaecologic oncologist, surgical teacher and consumer advocate. His international leadership and research impact was acknowledged in 2020 by the Australian community, when he was awarded an NHMRC Investigator Fellowship Level 2 (2021-25). The national impact of his research was recognised in 2017, when he was awarded Cancer Australia’s Jeannie Ferris Recognition Award (2017), for outstanding achievements in clinical practice and research. He is deeply engaged in consumer involvement and co-founded and serves on the Board of the Cherish Foundation, a consumer-focussed organisation that funds clinical research in better treatments for women with gynaecological cancers.
Works
Search Professor Andreas Obermair’s works on UQ eSpace
2001
Journal Article
Expression of hypoxia-inducible factor 1 alpha in epithelial ovarian tumors: Its impact on prognosis and on response to chemotherapy
Birner, P, Schindl, M, Obermair, A, Breitenecker, G and Oberhuber, G (2001). Expression of hypoxia-inducible factor 1 alpha in epithelial ovarian tumors: Its impact on prognosis and on response to chemotherapy. Clinical Cancer Research, 7 (6), 1661-1668.
2001
Journal Article
Prognostic value of beta 1-integrin (=CD29) in serous adenocarcinomas of the ovary
Muller-Klingspor, V, Hefler, L, Obermair, A, Kaider, A, Breitenecker, G, Leodolter, S and Kohlberger, P (2001). Prognostic value of beta 1-integrin (=CD29) in serous adenocarcinomas of the ovary. Anticancer Research, 21 (3C), 2185-2188.
2001
Journal Article
Three-dimensional ultrasound of the female urethra: comparing transvaginal and transrectal scanning
Umek, WH, Obermair, A, Stutterecker, D, Hausler, G, Leodolter, S and Hanzal, E (2001). Three-dimensional ultrasound of the female urethra: comparing transvaginal and transrectal scanning. Ultrasound in Obstetrics & Gynecology, 17 (5), 425-430. doi: 10.1046/j.1469-0705.2001.00416.x
2001
Journal Article
Impact of second look laparotomy and secondary cytoreductive surgery at second-look laparotomy in ovarian cancer patients
Obermair, A and Sevelda, P (2001). Impact of second look laparotomy and secondary cytoreductive surgery at second-look laparotomy in ovarian cancer patients. Acta Obstetricia Et Gynecologica Scandinavica, 80 (5), 432-436. doi: 10.1034/j.1600-0412.2001.080005432.x
2001
Journal Article
Prognostic parameters in endometrial stromal sarcoma: A clinicopathologic study in 31 patients
Bodner, K, Bodner-Adler, B, Obermair, A, Windbichler, G, Petru, E, Mayerhofer, S, Czerwenka, K, Leodolter, S, Kainz, C and Mayerhofer, K (2001). Prognostic parameters in endometrial stromal sarcoma: A clinicopathologic study in 31 patients. Gynecologic Oncology, 81 (2), 160-165. doi: 10.1006/gyno.2001.6152
2001
Journal Article
Peritoneal cytology: impact on disease-free survival in clinical stage I endometrioid adenocarcinoma of the uterus
Obermair, A., Geramou, M., Tripcony, L., Nicklin, J. L., Perrin, L. and Crandon, A. J. (2001). Peritoneal cytology: impact on disease-free survival in clinical stage I endometrioid adenocarcinoma of the uterus. Cancer Letters, 164 (1), 105-110. doi: 10.1016/S0304-3835(00)00722-9
2001
Journal Article
Primary Bartholin gland carcinoma: a report of seven cases
Obermair, A., Holler, S., Crandon, A. J., Perrin, L. C. and Nicklin, J. L. (2001). Primary Bartholin gland carcinoma: a report of seven cases. Australian & New Zealand Journal of Obstetrics & Gynaecology, 41 (1), 78-81. doi: 10.1111/j.1479-828X.2001.tb01299.x
2001
Journal Article
Lymphatic microvessel density as a novel prognostic factor in early-stage invasive cervical cancer
Birner, P, Schindl, M, Obermair, A, Breitenecker, G, Kowalski, H and Oberhuber, G (2001). Lymphatic microvessel density as a novel prognostic factor in early-stage invasive cervical cancer. International Journal of Cancer, 95 (1), 29-33. doi: 10.1002/1097-0215(20010120)95:13.0.CO;2-W
2001
Conference Publication
Increased microvessel density in adenomyosis uteri
Schindl, M, Birner, P, Obermair, A, Kiesel, L and Wenzl, R (2001). Increased microvessel density in adenomyosis uteri. Meeting of the Austrian-Society-for-Gynecology-and-Obstetrics, Meran Italy, Jun 22-24, 2000. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/S0015-0282(00)01642-3
2001
Journal Article
Primary fallopian tube carcinoma: the Queensland experience
Obermair, A., Taylor, K. H., Janda, M., Nicklin, J. L., Crandon, A. J. and Perrin, L. C. (2001). Primary fallopian tube carcinoma: the Queensland experience. International Journal of Gynecological Cancer, 11 (1), 69-72. doi: 10.1046/j.1525-1438.2001.011001069.x
2001
Journal Article
Selective immunohistochemical staining of blood and lymphatic vessels reveals independent prognostic influence of blood and lymphatic vessel invasion in early-stage cervical cancer
Birner, P, Obermair, A, Schindl, M, Kowalski, H, Breitenecker, G and Oberhuber, G (2001). Selective immunohistochemical staining of blood and lymphatic vessels reveals independent prognostic influence of blood and lymphatic vessel invasion in early-stage cervical cancer. Clinical Cancer Research, 7 (1), 93-97.
2001
Journal Article
Safety and efficacy of low anterior en bloc resection as part of cytoreductive surgery for patients with ovarian cancer
Obermair, A., Hagenauer, S., Tamandl, D., Clayton, R. D., Nicklin, J. L., Perrin, L. C., Ward, B. G. and Crandon, A. J. (2001). Safety and efficacy of low anterior en bloc resection as part of cytoreductive surgery for patients with ovarian cancer. Gynecologic Oncology, 83 (1), 115-120. doi: 10.1006/gyno.2001.6353
2001
Journal Article
Angiogenesis in cervical carcinoma
Obermair, A., Preyer, O. and Bachtiary, B. (2001). Angiogenesis in cervical carcinoma. CME Journal of Gynecologic Oncology, 6 (2), 184-191.
2000
Journal Article
Lymphatic microvessel density in epithelial ovarian cancer: Its impact on prognosis
Birner, P, Schindl, M, Obermair, A, Plank, C, Breitenecker, G, Kowalski, H and Oberhuber, G (2000). Lymphatic microvessel density in epithelial ovarian cancer: Its impact on prognosis. Anticancer Research, 20 (5A), 2981-2985.
2000
Journal Article
Overexpression of hypoxia-inducible factor 1 alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer
Birner, P, Schindl, M, Obermair, A, Plank, C, Breitenecker, G and Oberhuber, G (2000). Overexpression of hypoxia-inducible factor 1 alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Research, 60 (17), 4693-4696.
2000
Conference Publication
Quality of life changes during conformal radiation therapy for prostate carcinoma
Janda, M, Gerstner, N, Obermair, A, Fuerst, A, Wachter, S, Dieckmann, K and Potter, R (2000). Quality of life changes during conformal radiation therapy for prostate carcinoma. 35th Annual Meeting of the American-Society-of-Clinical-Oncology, Atlanta Georgia, May 15-18, 1999. doi: 10.1002/1097-0142(20000915)89:63.0.CO;2-D
2000
Journal Article
Tumor anemia and thrombocytosis in patients with vulvar cancer
Hefler, L, Mayerhofer, K, Leibman, B, Obermair, A, Reinthaller, A, Kainz, C and Tempfer, C (2000). Tumor anemia and thrombocytosis in patients with vulvar cancer. Tumor Biology, 21 (5), 309-314. doi: 10.1159/000030136
2000
Journal Article
Multiple myeloma with deletion of chromosome 13q is characterized by increased bone marrow neovascularization
Schreiber, S, Ackermann, J, Obermair, A, Kaufmann, H, Urbauer, E, Aletaha, K, Gisslinger, H, Chott, A, Huber, H and Drach, J (2000). Multiple myeloma with deletion of chromosome 13q is characterized by increased bone marrow neovascularization. British Journal of Haematology, 110 (3), 605-609. doi: 10.1046/j.1365-2141.2000.02248.x
2000
Journal Article
Austrian women's attitudes toward and knowledge of breast self-examination
Janda, M, Obermair, A, Haidinger, G, Waldhoer, T and Vutuc, C (2000). Austrian women's attitudes toward and knowledge of breast self-examination. Journal of Cancer Education, 15 (2), 91-94.
2000
Journal Article
Impact of hysteroscopy on disease-free survival in clinically stage I endometrial cancer patients
Obermair, A, Geramou, M, Gucer, F, Denison, U, Graf, AH, Kapshammer, E, Medl, M, Rosen, A, Wierrani, F, Neunteufel, W, Frech, I, Preyer, O, Speiser, P, Kainz, C and Austrian Gynecol Oncol Stu (2000). Impact of hysteroscopy on disease-free survival in clinically stage I endometrial cancer patients. International Journal of Gynecological Cancer, 10 (4), 275-279. doi: 10.1046/j.1525-1438.2000.010004275.x
Funding
Current funding
Past funding
Supervision
Availability
- Professor Andreas Obermair is:
- Available for supervision
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Available projects
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feMMe: Uterus-preserving treatment of endometrial cancer
In 2020 we completed the feMMe, phase 2 cliniccal trial which established anticancer activity of levonorgestrel intrauterrine device (LNG-IUD) to treat endometrial cancer. The next two steps towards estabnlioshing this treatment for larger groups of patients include:
1. To determine factors that predict response to LNG-IUD
2. To determine long-term patient outcomes including survival, fertility, and patient needs.
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Improving Quality of Survival for Women with Gynaecological Cancer
- Focus on improving quality of life, health & function during & after gynaecological cancer treatment, with a focus on biomarker research, implementation research and cancer survivorship.
Supervision history
Current supervision
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Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Principal Advisor
Other advisors: Dr Eva Baxter, Dr Zoe West, Professor Andrew Martin
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Master Philosophy
Patterns of care in endometrial cancer management in Queensland: a retrospective analysis.
Principal Advisor
Other advisors: Dr Eva Baxter
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Doctor Philosophy
Diet quality and composition in Australian women with endometrial cancer
Associate Advisor
Other advisors: Professor Monika Janda
Completed supervision
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2014
Doctor Philosophy
Hereditary endometrial cancer: Improving identification and referral of patients with suspected Lynch syndrome
Principal Advisor
Other advisors: Honorary Professor Amanda Spurdle, Associate Professor Lisa Fitzgerald
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2008
Doctor Philosophy
Nutritional status of patients with gynaecological cancer -
Joint Principal Advisor
Other advisors: Emeritus Professor Geoffrey Cleghorn
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Media
Enquiries
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