Overview
Background
Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC Research). He is a Professor of Gynaecological Oncology since 2007, a Senior Medical Officer at Royal Brisbane & Women’s Hospital and a Visiting Medical Officer at St Andrews War Memorial Hospital and Buderim Private Hospital. He holds an Honorary title of Professor at UQ since 2006.
Professor Obermair is an internationally recognised leader in gynaecological oncology research and treatment and has lead the research team at QCGC Research since establishing it in 2003.
Availability
- Professor Andreas Obermair is:
- Available for supervision
Fields of research
Qualifications
- Doctoral Diploma of Medicine, International University Vienna
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
Research interests
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Clinical Trials
Decisions on cancer management ideally are based on the results of high-level evidence, obtained through clinical trials whenever possible. As a principle, a new (proposed better) intervention should be compared to the current standard treatment before being made available generally. Outside a clinical trial new treatments should not become available until evidence has become available to demonstrate superiority over the current standard treatment. Retrospective studies harbour the risk that biases influenced outcomes. At QCGC Research we engage in phase 2 and 3 clinical trials. In large phase trials, patients are allocated randomly to one of two or more interventions in order to minimise the risk of bias. Generally, patients treated within clinical trials have a better outcome compared to patients who are not treated in clinical trials. As the Director of Research Gynaecological Oncology I am currently involved in developing and managing clinical trials in gynaecological cancers.
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Translational Research
The focus of QCGC Research's translational research program is the application of new technology (molecular, biochemical, imaging and surgical) to prevention, detection and therapy for gynaecological cancers.
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Quality of Life Research
Cancer specialists are aware that not only the survival time but also the quality of life is a key factor in cancer treatment. This is especially important when two treatments are equally effective but cause different side-effects. My Quality-of-Life research focuses on ovarian, endometrial, cervical and vulval cancer. I wish to provide the best, most effective and modern treatment to my patients with least possible detriments to quality of life.
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Minimally Invasive Surgery
In Australia, around 30,000 hysterectomies are conducted annually to treat uterine cancer and various benign gynaecological conditions. While open abdominal surgery may be necessary in around 10% of cases, evidence shows that less-invasive approaches, such as total laparoscopic hysterectomy (TLH) can achieve better outcomes for women at a lower overall cost to the health system. Yet, in Queensland, four of ten hysterectomies are still conducted by open abdominal surgery. Our own research has shown that many Australian surgeons are keen to adopt new techniques such as TLH, but that the lack of systematic training and mentoring opportunities is the main impediment to practice-change. Together with gynaecological surgical teams at hospitals and industry support we developed a prototype for system-level transformative practice change in gynaecological surgery.
Research impacts
Professor Obermair is an innovative and skilled gynaecologic oncologist, surgical teacher and consumer advocate. His international leadership and research impact was acknowledged in 2020 by the Australian community, when he was awarded an NHMRC Investigator Fellowship Level 2 (2021-25). The national impact of his research was recognised in 2017, when he was awarded Cancer Australia’s Jeannie Ferris Recognition Award (2017), for outstanding achievements in clinical practice and research. He is deeply engaged in consumer involvement and co-founded and serves on the Board of the Cherish Foundation, a consumer-focussed organisation that funds clinical research in better treatments for women with gynaecological cancers.
Works
Search Professor Andreas Obermair’s works on UQ eSpace
1999
Journal Article
Prognostic significance of tumor angiogenesis in epithelial ovarian cancer
Obermair, A, Wasicky, R, Kaider, A, Preyer, O, Losch, A, Leodolter, S and Kolbl, H (1999). Prognostic significance of tumor angiogenesis in epithelial ovarian cancer. Cancer Letters, 138 (1-2), 175-182. doi: 10.1016/S0304-3835(99)00005-1
1999
Journal Article
Prognostic significance of tumor angiogenesis in endometrial cancer
Obermair, A, Tempfer, C, Wasicky, R, Kaider, A, Hefler, L and Kainz, C (1999). Prognostic significance of tumor angiogenesis in endometrial cancer. Obstetrics and Gynecology, 93 (3), 367-371. doi: 10.1016/S0029-7844(98)00417-7
1999
Journal Article
Comparison of flow cytometry and RT-PCR for the detection of ovarian cancer cells in peripheral blood
Stimpfl, M, Schmid, BC, Obermair, A, Tong, D, Schiebel, I, Gitsch, G, Leodolter, S and Zeillinger, R (1999). Comparison of flow cytometry and RT-PCR for the detection of ovarian cancer cells in peripheral blood. Oncology Research, 11 (8), 367-373.
1998
Journal Article
Prediction of toxicity but not of clinical course by determining carboplatin exposure in patients with epithelial ovarian cancer treated with a combination of carboplatin and cisplatin
Obermair, A, Speiser, P, Thoma, M, Kaider, A, Salzer, H, Dittrich, C and Sevelda, P (1998). Prediction of toxicity but not of clinical course by determining carboplatin exposure in patients with epithelial ovarian cancer treated with a combination of carboplatin and cisplatin. International Journal of Oncology, 13 (5), 1023-1030.
1998
Journal Article
Epidemiologic considerations on the significance of hormones in carcinogenesis
Obermair, A, Jirecek, S and Leodolter, S (1998). Epidemiologic considerations on the significance of hormones in carcinogenesis. Gynakologisch-Geburtshilfliche Rundschau, 38 (2), 73-79. doi: 10.1159/000022235
1998
Journal Article
p53 protein overexpression: A strong prognostic factor in uterine papillary serous carcinoma
Bancher-Todesca, D, Gitsch, G, Williams, KE, Kohlberger, P, Neunteufel, W, Obermair, A, Heinze, G, Breitenecker, G and Hacker, NF (1998). p53 protein overexpression: A strong prognostic factor in uterine papillary serous carcinoma. Gynecologic Oncology, 71 (1), 59-63. doi: 10.1006/gyno.1998.5113
1998
Journal Article
Vascular endothelial growth factor serum concentrations in ovarian cancer
Tempfer, C, Obermair, A, Hefler, L, Haeusler, G, Gitsch, G and Kainz, C (1998). Vascular endothelial growth factor serum concentrations in ovarian cancer. Obstetrics and Gynecology, 92 (3), 360-363. doi: 10.1016/S0029-7844(98)00190-2
1998
Journal Article
The relationship of pretreatment serum hemoglobin level to the survival of epithelial ovarian carcinoma patients
Obermair, Andreas, Handisurya, Alessandra, Kaider, Alexandra, Sevelda, Paul, Kölbl, Heinz and Gitsch, Gerald (1998). The relationship of pretreatment serum hemoglobin level to the survival of epithelial ovarian carcinoma patients. Cancer, 83 (4), 726-731. doi: 10.1002/(sici)1097-0142(19980815)83:43.3.co;2-g
1998
Conference Publication
The relationship of pretreatment serum hemoglobin level to the survival of epithelial ovarian carcinoma patients - A prospective review
Obermair, A, Handisurya, A, Kaider, A, Sevelda, P, Kolbl, H and Gitsch, G (1998). The relationship of pretreatment serum hemoglobin level to the survival of epithelial ovarian carcinoma patients - A prospective review. 10th Annual Meeting of European-Society-of-Gynaecological-Oncology, Coimbra Portugal, Apr 26-May 02, 1997. doi: 10.1002/(SICI)1097-0142(19980815)83:43.0.CO;2-U
1998
Journal Article
Influence of intratumoral basic fibroblast growth factor concentration on survival in ovarian cancer patients
Obermair, A, Speiser, P, Reisenberger, K, Ullrich, R, Czerwenka, K, Kaider, A, Zeillinger, R and Miksche, M (1998). Influence of intratumoral basic fibroblast growth factor concentration on survival in ovarian cancer patients. Cancer Letters, 130 (1-2), 69-76. doi: 10.1016/S0304-3835(98)00119-0
1998
Journal Article
Concentration of vascular endothelial growth factor (VEGF) in the serum of patients with suspected ovarian cancer
Obermair, A., Tempfer, C., Hefler, L., Preyer, O., Kaider, A., Zeillinger, R., Leodolter, S. and Kainz, C. (1998). Concentration of vascular endothelial growth factor (VEGF) in the serum of patients with suspected ovarian cancer. British Journal of Cancer, 77 (11), 1870-1874. doi: 10.1038/bjc.1998.311
1998
Journal Article
Onycholysis in patients treated with docetaxel
Obermair, A, Binder, M, Barrada, M, Bancher-Todesca, D, Asseryanis, E and Kubista, E (1998). Onycholysis in patients treated with docetaxel. Annals of Oncology, 9 (2), 230-231. doi: 10.1023/A:1008218824342
1998
Journal Article
The influence of vascular space involvement on the prognosis of patients with stage IB cervical carcinoma - Correlation of results from hematoxylin and eosin staining with results from immunostaining for factor VIII-related antigen
Obermair, A, Wanner, C, Bilgi, S, Speiser, P, Reisenberger, K, Kaider, A, Kainz, C, Leodolter, S, Breitenecker, G and Gitsch, G (1998). The influence of vascular space involvement on the prognosis of patients with stage IB cervical carcinoma - Correlation of results from hematoxylin and eosin staining with results from immunostaining for factor VIII-related antigen. Cancer, 82 (4), 689-696. doi: 10.1002/(SICI)1097-0142(19980215)82:43.0.CO;2-U
1998
Journal Article
Tumor angiogenesis in stage IB cervical cancer: Correlation of microvessel density with survival
Obermair, A, Wanner, C, Bilgi, S, Speiser, P, Kaider, A, Reinthaller, A, Leodolter, S and Gitsch, G (1998). Tumor angiogenesis in stage IB cervical cancer: Correlation of microvessel density with survival. American Journal of Obstetrics and Gynecology, 178 (2), 314-319. doi: 10.1016/S0002-9378(98)80018-5
1998
Conference Publication
Prognostic impact of microvessel density in stage IB carcinoma of the uterine cervix
Obermair, A, Wanner, C, Bilgi, S, Speiser, P, Kaider, A, Reinthaller, A, Leodolter, S and Gitsch, G (1998). Prognostic impact of microvessel density in stage IB carcinoma of the uterine cervix. DORDRECHT: KLUWER ACADEMIC PUBL.
1998
Journal Article
Color-coded and spectral Doppler flow in breast carcinomas - Relationship with the tumor microvasculature
Peters-Engl, C, Medl, M, Mirau, M, Wanner, C, Bilgi, S, Sevelda, P and Obermair, A (1998). Color-coded and spectral Doppler flow in breast carcinomas - Relationship with the tumor microvasculature. Breast Cancer Research and Treatment, 47 (1), 83-89. doi: 10.1023/A:1005992916193
1997
Journal Article
Management of incomplete resected cervical neoplasia after LLETZ-conization
Banchertodesca, D, Obermair, A, Zeisler, H, Prainsack, D, Gitsch, G and Reinthaller, A (1997). Management of incomplete resected cervical neoplasia after LLETZ-conization. Geburtshilfe Und Frauenheilkunde, 57 (8), 458-462. doi: 10.1055/s-2007-1023117
1997
Journal Article
Vascular endothelial growth factor (VEGF) in human breast cancer: Correlation with disease-free survival
Obermair, A, Kucera, E, Mayerhofer, K, Speiser, P, Seifert, M, Czerwenka, K, Kaider, A, Leodolter, S, Kainz, C and Zeillinger, R (1997). Vascular endothelial growth factor (VEGF) in human breast cancer: Correlation with disease-free survival. International Journal of Cancer, 74 (4), 455-458. doi: 10.1002/(SICI)1097-0215(19970822)74:43.0.CO;2-8
1997
Journal Article
Management of incomplete resected cervical neoplasia after LLETZ-conization Management unvollstandig entfernter Lasionen nach Schlingenkonisation
Bancher-Todesca, D., Obermair, A., Zeisler, H., Prainsack, D., Gitsch, G. and Reinthaller, A. (1997). Management of incomplete resected cervical neoplasia after LLETZ-conization Management unvollstandig entfernter Lasionen nach Schlingenkonisation. Geburtshilfe und Frauenheilkunde, 57 (8), 458-462.
1997
Journal Article
Correlation of vascular endothelial growth factor expression and microvessel density in cervical intraepithelial neoplasia
Obermair, A, BancherTodesca, D, Bilgi, S, Kaider, A, Kohlberger, P, MullauerErtl, S, Leodolter, S and Gitsch, G (1997). Correlation of vascular endothelial growth factor expression and microvessel density in cervical intraepithelial neoplasia. Journal of the National Cancer Institute, 89 (16), 1212-1217. doi: 10.1093/jnci/89.16.1212
Funding
Current funding
Past funding
Supervision
Availability
- Professor Andreas Obermair is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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feMMe: Uterus-preserving treatment of endometrial cancer
In 2020 we completed the feMMe, phase 2 cliniccal trial which established anticancer activity of levonorgestrel intrauterrine device (LNG-IUD) to treat endometrial cancer. The next two steps towards estabnlioshing this treatment for larger groups of patients include:
1. To determine factors that predict response to LNG-IUD
2. To determine long-term patient outcomes including survival, fertility, and patient needs.
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Improving Quality of Survival for Women with Gynaecological Cancer
- Focus on improving quality of life, health & function during & after gynaecological cancer treatment, with a focus on biomarker research, implementation research and cancer survivorship.
Supervision history
Current supervision
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Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Principal Advisor
Other advisors: Dr Eva Baxter, Dr Zoe West, Professor Andrew Martin
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Master Philosophy
Patterns of care in endometrial cancer management in Queensland: a retrospective analysis.
Principal Advisor
Other advisors: Dr Eva Baxter
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Doctor Philosophy
Diet quality and composition in Australian women with endometrial cancer
Associate Advisor
Other advisors: Professor Monika Janda
Completed supervision
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2014
Doctor Philosophy
Hereditary endometrial cancer: Improving identification and referral of patients with suspected Lynch syndrome
Principal Advisor
Other advisors: Honorary Professor Amanda Spurdle, Associate Professor Lisa Fitzgerald
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2008
Doctor Philosophy
Nutritional status of patients with gynaecological cancer -
Joint Principal Advisor
Other advisors: Emeritus Professor Geoffrey Cleghorn
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Media
Enquiries
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