Overview
Background
Professor Andrew Mallett is a Nephrologist with a special interest in inherited kidney disease and nephrogenetics. After graduating from James Cook University (MBBS, 2006) he completed physician training at Mackay Base Hospital, Royal Brisbane and Women's Hospital and Princess Alexandra Hospital (MMed USyd, 2009; AFRACMA 2011; FRACP 2013; FASN 2016). Professor Mallett has undertaken a Churchill Fellowship and been a recurrent Visiting Fellow at Addenbrooke's Hospital (Cambridge, UK) and the Cambridge Institute for Medical Research (University of Cambridge). He has completed a PhD in nephrogenetics collaborating nationally and internationally, and is a Consultant Nephrologist at RBWH, co-leading the statewide Queensland Conjoint Renal Genetics Service. Professor Mallett is National Director of KidGen, the AGHA Renal Genetics Rare Disease Flagship.
Availability
- Dr Andrew Mallett is:
- Available for supervision
- Media expert
Works
Search Professor Andrew Mallett’s works on UQ eSpace
2025
Journal Article
Endpoint selection in autosomal dominant polycystic kidney disease clinical trials
St Pierre, Kitty, El-Damanawi, Ragada, Jefferis, Julia, Johnson, David W., Hawley, Carmel M., Staatz, Christine E., Viecelli, Andrea K. and Mallett, Andrew J. (2025). Endpoint selection in autosomal dominant polycystic kidney disease clinical trials. Kidney International Reports, 10 (11), 3773-3784. doi: 10.1016/j.ekir.2025.09.024
2025
Journal Article
A pilot study of pharmacogenomics in patients with kidney failure of an unknown cause
Lim, Ru Sin, Chung, Yue Ling, Biros, Erik, Harris, Trudie, Fowles, Lindsay, Patel, Chirag, Scuderi, Carla, Tchan, Michel, Rangan, Gopala, Mallawaarachchi, Amali, Faull, Randall, Huntley, Vanessa and Mallett, Andrew J. (2025). A pilot study of pharmacogenomics in patients with kidney failure of an unknown cause. Kidney International Reports, 10 (11), 4065-4068. doi: 10.1016/j.ekir.2025.08.015
2025
Journal Article
Presentation patterns of renal colic – a retrospective study of nephrolithiasis in North Queensland
Oly, Anu, Vangaveti, Venkat N. and Mallett, Andrew J. (2025). Presentation patterns of renal colic – a retrospective study of nephrolithiasis in North Queensland. BJU International bju.70051. doi: 10.1111/bju.70051
2025
Conference Publication
Phenotype-Genotype Characteristics and Disease Progression of FAN1 Karyomegalic Interstitial Nephritis : SA-PO0655
Clince, Michelle, Elhassan, Elhussein Aamir Elzein, McAnallen, Susan Marie, Kidd, Kendrah O., Claes, Kathleen, Chung, Byung ha, Halbritter, Jan, Gale, Daniel P., Alawi, Intisar, Patel, Chirag, Mallett, Andrew John, Faguer, Stanislas, Knebelmann, Bertrand, Goucha Louzir, Rim, Jerbi, Mouna, Hildebrandt, Friedhelm, Sayer, John Andrew, Sperati, John, Zheng, Sijie, Guebessi, Nisrine Bennani, De Boeck, Koen, Iványi, Béla, Bleyer, Anthony J. and Conlon, Peter J. (2025). Phenotype-Genotype Characteristics and Disease Progression of FAN1 Karyomegalic Interstitial Nephritis : SA-PO0655. Kidney Week, Houston, TX United States, 5-9 November 2025. Philadelphia, PA United States: Ovid. doi: 10.1681/asn.2025ppjtme55
2025
Journal Article
Association of autosomal dominant polycystic kidney disease (ADPKD) with cardiovascular disease and mortality in patients with treated kidney failure
Jefferis, Julia, Mallett, Andrew J., Rangan, Gopi, Cho, Yeoungjee, Viecelli, Andrea K., Vangaveti, Venkat, Johnson, David W. and Hawley, Carmel M. (2025). Association of autosomal dominant polycystic kidney disease (ADPKD) with cardiovascular disease and mortality in patients with treated kidney failure. BMC Nephrology, 26 (1) 542, 542. doi: 10.1186/s12882-025-04185-1
2025
Journal Article
PKD1 5’UTR variants are a rare cause of disease in ADPKD and suggest a new focus for therapeutic development
Wedd, Laura, Hort, Yvonne, Patel, Chirag, Sayer, John A., Rius, Rocio, Mallett, Andrew J., Cottle, Denny L., Smyth, Ian M., Furlong, Timothy, Shine, John and Mallawaarachchi, Amali (2025). PKD1 5’UTR variants are a rare cause of disease in ADPKD and suggest a new focus for therapeutic development. European Journal of Human Genetics. doi: 10.1038/s41431-025-01949-z
2025
Journal Article
Using large genomic biobanks to generate insights into genetic kidney disease
Chang, Alexander R., Wongboonsin, Janewit, Mallett, Andrew J., Morales, Ana, Retterer, Kyle, Mirshahi, Tooraj and Sayer, John A. (2025). Using large genomic biobanks to generate insights into genetic kidney disease. Seminars in Nephrology, 45 (5) 151651, 151651. doi: 10.1016/j.semnephrol.2025.151651
2025
Journal Article
Models of care for the implementation of genetic testing in nephrology
Connaughton, Dervla M. and Mallett, Andrew J. (2025). Models of care for the implementation of genetic testing in nephrology. Seminars in Nephrology, 45 (5) 151649, 1-15. doi: 10.1016/j.semnephrol.2025.151649
2025
Journal Article
Implementation of Metformin Therapy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD): study protocol for a phase III, multi-centre, randomized, placebo-controlled trial evaluating the long-term efficacy of metformin in slowing the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease
St Pierre, Kitty, El-Damanawi, Ragada, Johnson, David W., Hawley, Carmel M., Viecelli, Andrea K., Jha, Vivekanand, Green, Suetonia C., Gesualdo, Loreto, Kiriwandeniya, Charani, Velayudham, Pushparaj, Vergara, Liza A., Mihala, Gabor, Matsuyama, Misa, Brent, Peta-Ann Paul, Mallett, Andrew J. and IMPEDE-PKD Global Steering Committee (2025). Implementation of Metformin Therapy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD): study protocol for a phase III, multi-centre, randomized, placebo-controlled trial evaluating the long-term efficacy of metformin in slowing the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease. Trials, 26 (1) 302. doi: 10.1186/s13063-025-09010-6
2025
Journal Article
Experiences of kidney transplantation for recipients in regional, rural, and remote Queensland – exploring the trials and tribulations
Watters, Tara K., Glass, Beverley D., Scholes-Robertson, Nicole J. and Mallett, Andrew J. (2025). Experiences of kidney transplantation for recipients in regional, rural, and remote Queensland – exploring the trials and tribulations. BMC Nephrology, 26 (1) 485, 485. doi: 10.1186/s12882-025-04412-9
2025
Journal Article
A systematic review of treatment for acute interstitial nephritis
Yu, Yalin, Biros, Erik, Chang, Xiao and Mallett, Andrew J. (2025). A systematic review of treatment for acute interstitial nephritis. Kidney International Reports, 10 (8), 2575-2584. doi: 10.1016/j.ekir.2025.05.009
2025
Journal Article
Clonal Haematopoiesis of Indeterminate Potential and Clinical Outcomes in Kidney Diseases : Unraveling Interconnection between Age, Kidney Disease, and Comorbidities
Jefferis, Julia and Mallett, Andrew J. (2025). Clonal Haematopoiesis of Indeterminate Potential and Clinical Outcomes in Kidney Diseases : Unraveling Interconnection between Age, Kidney Disease, and Comorbidities. Journal of the American Society of Nephrology, 36 (9) 10.1681/ASN.0000000808, 1683-1685. doi: 10.1681/asn.0000000808
2025
Journal Article
A case report of metastatic renal cell carcinoma and ANCA associated vasculitis
Taylor, Maddison, Rawlings, Cassandra, Kan, George, Mallett, Andrew J. and Harfield, Michelle (2025). A case report of metastatic renal cell carcinoma and ANCA associated vasculitis. BMC Nephrology, 26 (1) 345, 345. doi: 10.1186/s12882-025-04247-4
2025
Journal Article
Gene-Disease Relationships in Kidney Genetics
Gitau, Vanessa, Ratliff, Julie, Webb, Ryan, Mallett, Andrew and Ajuyah, Pamela (2025). Gene-Disease Relationships in Kidney Genetics. Seminars in Nephrology, 45 (5) 151647, 151647. doi: 10.1016/j.semnephrol.2025.151647
2025
Journal Article
Genetic Nephrology – Key Foundations for Kidney Medicine
Wongboonsin, Janewit and Mallett, Andrew J. (2025). Genetic Nephrology – Key Foundations for Kidney Medicine. Seminars in Nephrology, 45 (5) 151661, 151661. doi: 10.1016/j.semnephrol.2025.151661
2025
Journal Article
Genetic nephrology: an arising subspecialty in kidney medicine
Wongboonsin, Janewit and Mallett, Andrew J. (2025). Genetic nephrology: an arising subspecialty in kidney medicine. Seminars in Nephrology, 45 (4) 151652, 151652. doi: 10.1016/j.semnephrol.2025.151652
2025
Journal Article
Should genetic testing be indicated and implemented for chronic kidney disease of unknown cause?
Jefferis, Julia, Mallawaarachchi, Amali, Knoers, Nine, Blasco, Miquel and Mallett, Andrew J. (2025). Should genetic testing be indicated and implemented for chronic kidney disease of unknown cause?. Seminars in Nephrology, 45 (4) 151659, 151659. doi: 10.1016/j.semnephrol.2025.151659
2025
Journal Article
Health professional and transplant recipient perspectives of kidney transplantation in regional, rural, and remote Australia – a survey study
Watters, Tara K., Scholes-Robertson, Nicole J., Glass, Beverley D. and Mallett, Andrew J. (2025). Health professional and transplant recipient perspectives of kidney transplantation in regional, rural, and remote Australia – a survey study. Journal of Nephrology, 38 (5), 1403-1412. doi: 10.1007/s40620-025-02331-4
2025
Journal Article
Genetic kidney disease across the lifespan – emerging insights from clinical genomics in older people
Nicholls, Kathleen and Mallett, Andrew J. (2025). Genetic kidney disease across the lifespan – emerging insights from clinical genomics in older people. Kidney International Reports, 10 (8), 2548-2550. doi: 10.1016/j.ekir.2025.06.050
2025
Journal Article
Exploring the pharmacist's role in regional, rural, and remote kidney transplant care: perspectives of health professionals and transplant recipients
Watters, Tara K., Scholes-Robertson, Nicole J., Mallett, Andrew J. and Glass, Beverley D. (2025). Exploring the pharmacist's role in regional, rural, and remote kidney transplant care: perspectives of health professionals and transplant recipients. Exploratory Research in Clinical and Social Pharmacy, 18 100587, 100587. doi: 10.1016/j.rcsop.2025.100587
Funding
Current funding
Past funding
Supervision
Availability
- Dr Andrew Mallett is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Sample sub-group algorithm bias analysis for machine learning evaluation in the clinical domain
Associate Advisor
Other advisors: Professor Clair Sullivan, Professor Guido Zuccon, Mr Anton Van Der Vegt
Completed supervision
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2025
Doctor Philosophy
Establishing the Role of Metformin for ADPKD Through Therapeutic Investigation and Guideline Development
Principal Advisor
Other advisors: Professor David Johnson, Dr Christine Staatz, Professor Carmel Hawley, Associate Professor Andrea Viecelli
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2023
Doctor Philosophy
Defining the cellular milieu within the clear cell renal cell carcinoma microenvironment
Principal Advisor
Other advisors: Dr Andrew Kassianos, Dr Quan Nguyen
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2024
Doctor Philosophy
Improving patient centred outcomes in kidney transplant recipients
Associate Advisor
Other advisors: Dr Christine Staatz
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2022
Doctor Philosophy
Rab GTPase Regulation of Primary Cilia in Renal Epithelium
Associate Advisor
Other advisors: Professor Jennifer Stow
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2022
Master Philosophy
Rab GTPase Regulation of Cell Surface Protrusions
Associate Advisor
Other advisors: Professor Jennifer Stow
Media
Enquiries
Contact Dr Andrew Mallett directly for media enquiries about:
- Alport Syndrome
- clinical genomic
- genetic kidney disease
- genetics
- genomics
- inherited kidney disease
- kidney
- kidney disease
- kidney genetics
- nephrology
- polycystic kidney disease
- renal genetics
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