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Live molecular imaging using super resolution microscopy, two photon and spinning disk confocal microscopy (2013-2014)

Abstract

A new era of molecular live imaging has begun which allows rapid 3-D visualisation of biological processes such as brain wiring in vivo down to the tracking of a single molecule. This relies on recent advances in imaging including multiphoton, spinning-disk and particularly super-resolution microscopy. The goal of this application is to establish the first multi-instrument super-resolution system in Queensland, allowing a team of multi-institutional cross-disciplinary researchers to use these emerging technologies to image single molecules within the cellular environment in living cells. Such insight is key to understanding basical biological interactions that govern brain wiring, communication between cells, and cell-cell adhesion.

Experts

Professor Frederic Meunier

Affiliate of Clem Jones Centre for
Clem Jones Centre for Ageing Dementia Research
Queensland Brain Institute
Affiliate Professor of Institute fo
Institute for Molecular Bioscience
Professor and Academic Senior Group
Queensland Brain Institute
Frederic Meunier
Frederic Meunier

Professor Alpha Yap

Professor and ARC Laureate Fellow
Institute for Molecular Bioscience
Affiliate of The Centre for Cell Bi
Centre for Cell Biology of Chronic Disease
Institute for Molecular Bioscience
Affiliate Professor of School of Bi
School of Biomedical Sciences
Faculty of Medicine
Alpha Yap
Alpha Yap

Professor Halina Rubinsztein-Dunlop

Affiliate of ARC COE for Engineered
ARC Centre of Excellence for Engineered Quantum Systems
Faculty of Science
Affiliate of ARC COE in Quantum Bio
ARC Centre of Excellence in Quantum Biotechnology
Faculty of Science
Professor
School of Mathematics and Physics
Faculty of Science
Halina Rubinsztein-Dunlop
Halina Rubinsztein-Dunlop