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Evolution of the marsupial gut microbiome and adaptation to eucalypt toxins (2015-2017)

Abstract

Eucalyptus leaves comprise all or part of the diet of some masurpials including koalas. Gut microbiota assist in the ability of these folivores to tolerate eucalyptus toxins although present understanding is rudimentary. This project will use culture-independent molecular methods to identify and characterise gut populations involved in phytochemical detoxification by comparative analysis with diprotodont relatives that are not capable of digesting eucalyptus leaves. This will highlight evolutionary convergence of gut microbiomes in toxic folivores and reveal mechanisms by which microorganisms respond to and metabolise eucalypt toxins. A broader evolutionary context of marsupial digestive function will assist in ongoing conservation efforts.

Experts

Professor Phil Hugenholtz

Centre Director of Australian Centre for Ecogenomics (ACE)
Australian Centre for Ecogenomics
Faculty of Science
Affiliate of ARC COE for Plant Success in Nature and Agriculture
ARC COE for Plant Success in Nature and Agriculture
Faculty of Science
Affiliate of Centre for Marine Science
Centre for Marine Science
Faculty of Science
Professor
School of Chemistry and Molecular Biosciences
Faculty of Science
Phil Hugenholtz
Phil Hugenholtz

Professor Mark Morrison

Affiliate Professor of School of Chemistry and Molecular Biosciences
School of Chemistry and Molecular Biosciences
Faculty of Science
Chair & Group Leader Metagenomics
Frazer Institute
Faculty of Health, Medicine and Behavioural Sciences
Mark Morrison
Mark Morrison