Reaching new heights in high-resolution electron microscopy (2015-2016)
Abstract
Direct Electron Detection cameras are a recent technological breakthrough delivering one of the greatest single advancements to the field of molecular cryo-EM. The aim of this proposal is to enable a "first of a kind" cryo-EM platform in Australia enabling high-throughput atomic resolution protein structure determination. This will be achieved by integrating a state-of-the-art Gatan K2 Summit Direct Electron Detection camera system into the established ~$15M cryo-EM facility managed by the UQ node of the Australian Microscopy & Microanalysis Facility. This will offer unique and significantly improved capabilities for atomic resolution protein structure analysis, and will support a broad range of projects across the biological sciences.
