Engineering a nanovaccine for cost-effective influenza poultry vaccination (2016-2019)
Abstract
The project aims to develop a new single-dose, room temperature-stable nanovaccine for cost-effective influenza poultry vaccination. The nanovaccine is based on viral protein assembly modularised to present multiple copies of influenza antigen. Particularly, this project focuses on the engineering of this vaccine manufacturing and formulation for a room temperature-stable vaccine. The resulting engineered vaccine will play an important role in preventing avian influenza outbreaks, which are currently affecting both developed and developing countries, costing millions of dollars due to the death and culling of infected poultry. This project will therefore significantly benefit the poultry industry.