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Genetic architecture and evolution of complex traits across populations (2022-2025)

Abstract

Most human traits have a genetic component and display substantial diversity within and among populations. How natural selection changes and maintains genetic variation in human traits is a long-standing question in evolution that the proposed project aims to answer. Using innovative statistical methods and largest genomic ¿big¿ datasets ever across populations of different ancestral backgrounds, this project expects to generate new knowledge on the roles of natural selection in shaping the genetic variation in traits and identify key factors that drive the differentiation of human populations. These outcomes will significantly improve our understanding on the evolution of human traits and adaptation of populations to changing environments.

Experts

Dr Jian Zeng

NHMRC Emerging Leadership Fellow - Group Leader
Institute for Molecular Bioscience
Jian Zeng
Jian Zeng

Professor Peter Visscher

ARC Laureate Fellow - GL
Institute for Molecular Bioscience
Peter Visscher
Peter Visscher