ESEG_Australian Microbial Biodiscovery: Exploration of Bioactive Chemical Space (2005-2006)

Abstract

This project will explore the drug discovery potential of bioactive metabolites isolated from Australian microbes through a program of biodiscovery supported by biomimetic total and combinatorial synthetic chemistry. To use privileged knowledge of bioactive Australian microbe metabolites to access new chemical space to accelerate the discovery of New Chemical Entities (NCEs). Molecular libraries assembled during this project will be a valuable resource for dug discovery

Experts

Professor Rob Capon

Affiliate of Centre for Marine Science: Centre for Marine Science; Faculty of Science

Affiliate of The Centre for Chemistry and Drug Discovery: Centre for Chemistry and Drug Discovery; Institute for Molecular Bioscience

Affiliate of ARC COE for Innovations in Peptide and Protein Science: ARC COE for Innovations in Peptide and Protein Science; Institute for Molecular Bioscience

Professorial Research Fellow - GL: Institute for Molecular Bioscience

Rob Capon

Professor Craig Williams

Professor: School of Chemistry and Molecular Biosciences; Faculty of Science

Craig Williams

Associate Professor Mark Smythe

Affiliate of The Centre for Chemistry and Drug Discovery: Centre for Chemistry and Drug Discovery; Institute for Molecular Bioscience

Principal Research Fellow - GL: Institute for Molecular Bioscience

Mark Smythe