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Featured

2014

Journal Article

Polarized immune responses modulated by layered double hydroxides nanoparticle conjugated with CpG

Yan, Shiyu, Rolfe, Barbara E., Zhang, Bing, Mohammed, Yousuf H., Gu, Wenyi and Xu, Zhi P. (2014). Polarized immune responses modulated by layered double hydroxides nanoparticle conjugated with CpG. Biomaterials, 35 (35), 9508-9516. doi: 10.1016/j.biomaterials.2014.07.055

Polarized immune responses modulated by layered double hydroxides nanoparticle conjugated with CpG

Featured

2014

Journal Article

Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways

Chen, Jiezhong, Shao, Renfu, Li, Li, Xu, Zhi Ping and Gu, Wenyi (2014). Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways. International Journal of Nanomedicine, 9 (1), 3403-3411. doi: 10.2147/IJN.S61633

Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways

Featured

2013

Journal Article

Nanoparticles mimicking viral surface topography for enhanced cellular delivery

Niu, Yuting, Yu, Meihua, Hartono, Sandy B., Yang, Jie, Xu, Hongyi, Zhang, Hongwei, Zhang, Jun, Zou, Jin, Dexter, Annette, Gu, Wenyi and Yu, Chengzhong (2013). Nanoparticles mimicking viral surface topography for enhanced cellular delivery. Advanced Materials, 25 (43), 6233-6237. doi: 10.1002/adma.201302737

Nanoparticles mimicking viral surface topography for enhanced cellular delivery

2013

Journal Article

An influenza virus-inspired polymer system for the timed release of siRNA

Truong, Nghia P., Gu, Wenyi, Prasadam, Indira, Jia, Zhongfan, Crawford, Ross, Xiao, Yin and Monteiro, Michael J. (2013). An influenza virus-inspired polymer system for the timed release of siRNA. Nature Communications, 4 (1) 1902, 1902. doi: 10.1038/ncomms2905

An influenza virus-inspired polymer system for the timed release of siRNA

Featured

2012

Journal Article

Poly-L-lysine functionalized large pore cubic mesostructured silica nanoparticles as biocompatible carriers for gene delivery

Hartono, Sandy B., Gu, Wenyi, Kleitz, Freddy, Liu, Jian, He, Lizhong, Middelberg, Anton P. J., Yu, Chengzhong, Lu, Gao Qing (Max) and Qiao, Shi Zhang (2012). Poly-L-lysine functionalized large pore cubic mesostructured silica nanoparticles as biocompatible carriers for gene delivery. ACS Nano, 6 (3), 2104-2117. doi: 10.1021/nn2039643

Poly-L-lysine functionalized large pore cubic mesostructured silica nanoparticles as biocompatible carriers for gene delivery

Featured

2009

Journal Article

Both treated and untreated tumors are eliminated by short hairpin RNA-based induction of target-specific immune responses

Gu, Wenyi, Cochrane, Melanie, Leggatt, Graham, Payne, Elizabeth, Choyce, Allison, Zhou, Fang, Tindle, Robert and McMillan, Nigel (2009). Both treated and untreated tumors are eliminated by short hairpin RNA-based induction of target-specific immune responses. Proceedings of the National Academy of Sciences of the United States of America, 106 (20), 8314-8319. doi: 10.1073/pnas.0812085106

Both treated and untreated tumors are eliminated by short hairpin RNA-based induction of target-specific immune responses

Featured

2007

Journal Article

Generalized substitution of isoencoding codons shortens the duration of papillomavirus L1 protein expression in transiently gene-transfected keratinocytes due to cell differentiation

Gu, Wenyi, Ding, Jianmin M., Wang, Xiao, de Kluyver, Rachel L., Saunders, Nicholas A., Frazer, Ian H. and Zhao, Kong-Nan (2007). Generalized substitution of isoencoding codons shortens the duration of papillomavirus L1 protein expression in transiently gene-transfected keratinocytes due to cell differentiation. Nucleic Acids Research, 35 (14), 4820-4832. doi: 10.1093/nar/gkm496

Generalized substitution of isoencoding codons shortens the duration of papillomavirus L1 protein expression in transiently gene-transfected keratinocytes due to cell differentiation

2024

Journal Article

Polymeric silk fibroin hydrogel as a conductive and multifunctional adhesive for durable skin and epidermal electronics

Fu, Fanfan, Liu, Changyi, Jiang, Zhenlin, Zhao, Qingyu, Shen, Aining, Wu, Yilun and Gu, Wenyi (2024). Polymeric silk fibroin hydrogel as a conductive and multifunctional adhesive for durable skin and epidermal electronics. Smart Medicine, 3 (3). doi: 10.1002/smmd.20240027

Polymeric silk fibroin hydrogel as a conductive and multifunctional adhesive for durable skin and epidermal electronics

2024

Journal Article

Bone targeted nano-drug and nano-delivery

Wu, Yilun, Sun, Bing, Tang, Ying, Shen, Aining, Lin, Yanlin, Zhao, Xiaohui, Li, Jingui, Monteiro, Michael J. and Gu, Wenyi (2024). Bone targeted nano-drug and nano-delivery. Bone Research, 12 (1) 51. doi: 10.1038/s41413-024-00356-2

Bone targeted nano-drug and nano-delivery

2024

Journal Article

Spatial heterogeneity and prognostic significance of TAMs and TILs infiltrates in different staging esophageal squamous carcinoma

Li, Ya, Liu, Jia, Qi, Liwen, Yuan, Xin, Yang, Kaige, Ren, Yilin, Shi, Qi, Xu, Guixuan, Wang, Weinan, Luo, Chenghua, Wang, Lianghai, Liang, Weihua, He, Zengtao, Zhou, Wenhu, Fei, Jing, Chen, Weigang, Gu, Wenyi, Li, Feng and Hu, Jianming (2024). Spatial heterogeneity and prognostic significance of TAMs and TILs infiltrates in different staging esophageal squamous carcinoma. Digestive and Liver Disease. doi: 10.1016/j.dld.2024.08.003

Spatial heterogeneity and prognostic significance of TAMs and TILs infiltrates in different staging esophageal squamous carcinoma

2024

Journal Article

RGD Density on Tadpole Nanostructures Regulates Cancer Stem Cell Proliferation and Stemness

Zhang, Dayong, Sun, Bing, Wang, Jingyi, Chen, Sung-Po R., Bobrin, Valentin A., Gu, Yushu, Ng, Chun Ki, Gu, Wenyi and Monteiro, Michael J. (2024). RGD Density on Tadpole Nanostructures Regulates Cancer Stem Cell Proliferation and Stemness. Biomacromolecules, 25 (8), 5260-5272. doi: 10.1021/acs.biomac.4c00645

RGD Density on Tadpole Nanostructures Regulates Cancer Stem Cell Proliferation and Stemness

2024

Journal Article

Folate-targeted nanocarriers co-deliver ganciclovir and miR-34a-5p for combined anti-KSHV therapy

Li, Fangling, Cao, Dongdong, Gu, Wenyi, Li, Dongmei, Liu, Zhiyong and Cui, Lin (2024). Folate-targeted nanocarriers co-deliver ganciclovir and miR-34a-5p for combined anti-KSHV therapy. International Journal of Molecular Sciences, 25 (5) 2932, 1-19. doi: 10.3390/ijms25052932

Folate-targeted nanocarriers co-deliver ganciclovir and miR-34a-5p for combined anti-KSHV therapy

2024

Journal Article

Effects of seipin on mouse mesenchymal stem cell Osteo-Adipogenic Balance

Li, Zeying, Jin, Shan, Xu, Tong, Chen, Hongzhi, Cai, Wenping, Du, Jin, Jin, Qiu, Zhuang, Sihui, Qi, Yan, Gu, Wenyi and Pang, Lijuan (2024). Effects of seipin on mouse mesenchymal stem cell Osteo-Adipogenic Balance. Stem Cells and Development (ja), 177-188. doi: 10.1089/scd.2023.0107

Effects of seipin on mouse mesenchymal stem cell Osteo-Adipogenic Balance

2024

Journal Article

An essential role of c-Fos in Notch1-mediated promotion of proliferation of KSHV-Infected SH-SY5Y Cells

Xu, Huiling, Huang, Jinghong, Yao, Lixia, Gu, Wenyi, Ruzi, Aynisahan, Ding, Yufei, Li, Ying, Liang, Weihua, Jiang, Jinfang, Pan, Zemin, Cao, Dongdong, Zhou, Naiming, Li, Dongmei and Zhang, Jinli (2024). An essential role of c-Fos in Notch1-mediated promotion of proliferation of KSHV-Infected SH-SY5Y Cells. Current Molecular Pharmacology, 17 e18761429264583, 1-13. doi: 10.2174/0118761429264583231106104202

An essential role of c-Fos in Notch1-mediated promotion of proliferation of KSHV-Infected SH-SY5Y Cells

2024

Journal Article

Targeted delivery of miR-34a-5p by phenylborate-coupled polyethylenimide nanocarriers for anti-KSHV treatment

Li, Fangling, Cao, Dongdong, Yao, Lixia, Gu, Wenyi, Liu, Zhiyong, Li, Dongmei and Cui, Lin (2024). Targeted delivery of miR-34a-5p by phenylborate-coupled polyethylenimide nanocarriers for anti-KSHV treatment. Frontiers in Bioengineering and Biotechnology, 11 ARTN 1343956, 1343956. doi: 10.3389/fbioe.2023.1343956

Targeted delivery of miR-34a-5p by phenylborate-coupled polyethylenimide nanocarriers for anti-KSHV treatment

2024

Journal Article

Chitosan-coated artesunate protects against ulcerative colitis via STAT6-mediated macrophage M2 polarization and intestinal barrier protection

Tao, Ya, Xu, Lei, Liu, Xiaopan, Wang, Peijia, Wei, Simin, Huang, Yinmo, Gu, Wenyi, Bo, Ruonan, Liu, Mingjiang, Yu, Jie and Li, Jingui (2024). Chitosan-coated artesunate protects against ulcerative colitis via STAT6-mediated macrophage M2 polarization and intestinal barrier protection. International Journal of Biological Macromolecules, 254 (Part 1) 127680, 127680. doi: 10.1016/j.ijbiomac.2023.127680

Chitosan-coated artesunate protects against ulcerative colitis via STAT6-mediated macrophage M2 polarization and intestinal barrier protection

2024

Journal Article

miR-769-3p inhibits cellular proliferation of KSHV-infected SH-SY5Y cells through targeting mTOR

Cao, Dongdong, Wu, Zhaofu, Yang, Rui, Yao, Lixia, Huang, Jinhong, Ding, Yufei, Ruzi, Aynisahan, Pan, Zemin, Pan, Yuanming, Li, Dongmei, Gu, Wenyi and Zhang, Jinli (2024). miR-769-3p inhibits cellular proliferation of KSHV-infected SH-SY5Y cells through targeting mTOR. Journal of Cancer, 15 (11), 3338-3349. doi: 10.7150/jca.93595

miR-769-3p inhibits cellular proliferation of KSHV-infected SH-SY5Y cells through targeting mTOR

2023

Journal Article

M2 tumor-associated macrophage mediates the maintenance of stemness to promote cisplatin resistance by secreting TGF-β1 in esophageal squamous cell carcinoma

Yang, Kaige, Xie, Yufang, Xue, Lele, Li, Fanping, Luo, Chenghua, Liang, Weihua, Zhang, Haijun, Li, Ya, Ren, Yilin, Zhao, Mengmeng, Wang, Weinan, Liu, Jia, Shen, Xihua, Zhou, Wenhu, Fei, Jing, Chen, Weigang, Gu, Wenyi, Wang, Lianghai, Li, Feng and Hu, Jianming (2023). M2 tumor-associated macrophage mediates the maintenance of stemness to promote cisplatin resistance by secreting TGF-β1 in esophageal squamous cell carcinoma. Journal of Translational Medicine, 21 (1) 26, 26. doi: 10.1186/s12967-022-03863-0

M2 tumor-associated macrophage mediates the maintenance of stemness to promote cisplatin resistance by secreting TGF-β1 in esophageal squamous cell carcinoma

2023

Journal Article

17‐β‐estradiol reduces surface PD‐L1 expression in estrogen receptor‐positive breast cancer but not type 1 endometrial cancer cells

Li, Hongzhuo, Gu, Wenyi, Jeffery, Penny and Chen, Chen (2023). 17‐β‐estradiol reduces surface PD‐L1 expression in estrogen receptor‐positive breast cancer but not type 1 endometrial cancer cells. Clinical and Translational Medicine, 13 (7) e1330, e1330. doi: 10.1002/ctm2.1330

17‐β‐estradiol reduces surface PD‐L1 expression in estrogen receptor‐positive breast cancer but not type 1 endometrial cancer cells

2023

Journal Article

Delivery of miR-34a-5p by folic acid-modified β-cyclodextrin-grafted polyethylenimine copolymer nanocarriers to resist KSHV

Li, Fangling, Cao, Dongdong, Gu, Wenyi, Cui, Lin, Qiu, Zhongpeng, Liu, Zhiyong, Li, Dongmei and Guo, Xuhong (2023). Delivery of miR-34a-5p by folic acid-modified β-cyclodextrin-grafted polyethylenimine copolymer nanocarriers to resist KSHV. ACS Applied Nano Materials, 6 (12), 10826-10836. doi: 10.1021/acsanm.3c02162

Delivery of miR-34a-5p by folic acid-modified β-cyclodextrin-grafted polyethylenimine copolymer nanocarriers to resist KSHV