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2017 Journal Article High-throughput expression of animal venom toxins in Escherichia coli to generate a large library of oxidized disulphide-reticulated peptides for drug discoveryTurchetto, Jeremy, Sequeira, Ana Filipa, Ramond, Laurie, Peysson, Fanny, Bras, Joana L. A., Saez, Natalie J., Duhoo, Yoan, Blemont, Marilyne, Guerreiro, Catarina I. P. D., Quinton, Loic, Pauw, Edwin de, Gilles, Nicolas, Darbon, Hervé, Fontes, Carlos M. G. A. and Vincentelli, Renaud (2017). High-throughput expression of animal venom toxins in Escherichia coli to generate a large library of oxidized disulphide-reticulated peptides for drug discovery. Microbial Cell Factories, 16 (1) 6, 6. doi: 10.1186/s12934-016-0617-1 |
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2017 Book Chapter A Strategy for production of correctly folded disulfide-rich peptides in the periplasm of E. coliSaez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra and King, Glenn F. (2017). A Strategy for production of correctly folded disulfide-rich peptides in the periplasm of E. coli. In Heterologous Gene Expression in E. coli Methods and Protocols (pp. 155-180) New York, NY United States: Humana Press. doi:10.1007/978-1-4939-6887-9_10 |
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2015 Journal Article Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1aSaez, Natalie J., Deplazes, Evelyne, Cristofori-Armstrong, Ben, Chassagnon, Irene R., Lin, Xiaozhen, Mobli, Mehdi, Mark, Alan E., Rash, Lachlan D. and King, Glenn F. (2015). Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a. British Journal of Pharmacology, 172 (20), 4985-4995. doi: 10.1111/bph.13267 |
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2014 Journal Article High throughput quantitative expression screening and purification applied to recombinant disulfide-rich venom proteins produced in E. coliSaez, Natalie J., Nozach, Herve, Blemont, Marilyne and Vincentelli, Renaud (2014). High throughput quantitative expression screening and purification applied to recombinant disulfide-rich venom proteins produced in E. coli. Journal of Visualized Experiments, 1091 (89) e51464, 33-53. doi: 10.3791/51464 |
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2014 Book Chapter High-throughput expression screening and purification of recombinant proteins in E-coliSaez, Natalie J. and Vincentelli, Renaud (2014). High-throughput expression screening and purification of recombinant proteins in E-coli. Structural genomics: General applications. (pp. 33-53) edited by Yu Wai Chen. New York United States: Humana Press. doi: 10.1007/978-1-62703-691-7_3 |
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2013 Journal Article Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coliKlint, Julie K., Senff, Sebastian, Saez, Natalie J., Seshadri, Radha, Lau, Ho Yee, Bende, Nira J., Undheim, Eivind A. B., Rash, Lachlan D., Mobli, Mehdi and King, Glenn F. (2013). Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli. PLoS One, 8 (5) e63865, e63865.1-e63865.12. doi: 10.1371/journal.pone.0063865 |
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2013 Journal Article High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coliNozach, Hervé, Fruchart-Gaillard, Carole, Fenaille, François, Beau, Fabrice, Ramos, Oscar Henrique Pereira, Douzi, Badreddine, Saez, Natalie J., Moutiez, Mireille, Servent, Denis, Gondry, Muriel, Thaï, Robert, Cuniasse, Philippe, Vincentelli, Renaud and Dive, Vincent (2013). High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli. Microbial Cell Factories, 12 (37) 37, 1-16. doi: 10.1186/1475-2859-12-37 |
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2013 Other Outputs Characterising the molecular basis of the interaction between the putative drug target ASIC1a and π-TRTX-Pc1aSaez, Natalie Jose (2013). Characterising the molecular basis of the interaction between the putative drug target ASIC1a and π-TRTX-Pc1a. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. |
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2011 Journal Article A dynamic pharmacophore drives the interaction between psalmotoxin-1 and the putative drug target acid-sensing ion channel 1aSaez, Natalie J., Mobli, Mehdi, Bieri, Michael, Chassagnon, Irene R., Malde, Alpeshkumar K., Gamsjaeger, Roland, Mark, Alan E., Gooley, Paul R., Rash. Lachlan D. and King, Glenn F. (2011). A dynamic pharmacophore drives the interaction between psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a. Molecular Pharmacology, 80 (5), 796-808. doi: 10.1124/mol.111.072207 |
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2011 Journal Article Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formationHu, Shu-Hong, Christie, Michelle P., Saez, Natalie J., Latham, Catherine F., Jarrott, Russell, Lua, Linda H. L., Collins, Brett M. and Martin, Jennifer L. (2011). Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation. Proceedings of the National Academy of Sciences of the United States of America, 108 (3), 1040-1045. doi: 10.1073/pnas.0914906108 |
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2010 Journal Article Spider-venom peptides as therapeuticsSeaz, Natalie J., Senff, Sebastian, Jensen, Jonas E., Er, Sing Yan, Herzig, Volker, Rash, Lachlan D. and King, Glenn F. (2010). Spider-venom peptides as therapeutics. Toxins, 2 (12), 2851-2871. doi: 10.3390/toxins2122851 |
