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2016

Journal Article

Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor

Begum, Anjuman Ara, Moyle, Peter M. and Toth, Istvan (2016). Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor. Bioorganic and Medicinal Chemistry, 24 (22), 5834-5841. doi: 10.1016/j.bmc.2016.09.039

Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor

2016

Journal Article

Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA delivery

Kamaruzaman, Khairul A., Moyle, Peter M. and Toth, Istvan (2016). Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA delivery. International Journal of Peptide Research and Therapeutics, 23 (1), 1-16. doi: 10.1007/s10989-016-9545-5

Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA delivery

2016

Journal Article

Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models

Rivera-Hernandez, Tania, Pandey, Manisha, Henningham, Anna, Cole, Jason, Choudhury, Biswa, Cork, Amanda J., Gillen, Christine M., Ghaffar, Khairunnisa Abdul, West, Nicholas P., Silvestri, Guido, Good, Michael F., Moyle, Peter M., Toth, Istvan, Nizet, Victor, Batzloff, Michael R. and Walker, Mark J. (2016). Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models. mBio, 7 (3) e00618-16, e00618-16.1-e00618-16.9. doi: 10.1128/mBio.00618-16

Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models

2016

Journal Article

Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity

Wan, Yu, Moyle, Peter M., Christie, Michelle P. and Toth, Istvan (2016). Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity. Nanomedicine, 11 (8), 907-919. doi: 10.2217/nnm.16.27

Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity

2016

Journal Article

Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines

Hussein, Waleed M., Liu, Tzu-Yu, Maruthayanar, Pirashanthini, Mukaida, Saori, Moyle, Peter M., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2016). Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines. Chemical Science, 7 (3), 2308-2321. doi: 10.1039/C5SC03859F

Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines

2015

Journal Article

Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors

Moyle, Peter M., Dai, Wei, Liu, Tzu-Yu, Hussein, Waleed M., Maruthayanar, Pirashanthini, Wells, James W., McMillan, Nigel A. J., Skwarczynski, Mariusz and Toth, Istvan (2015). Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors. Bioorganic and Medicinal Chemistry Letters, 25 (23), 5570-5575. doi: 10.1016/j.bmcl.2015.10.049

Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors

2015

Journal Article

Endosome escape strategies for improving the efficacy of oligonucleotide delivery systems

Wan, Yu, Moyle, Peter M and Toth, Istvan (2015). Endosome escape strategies for improving the efficacy of oligonucleotide delivery systems. Current Medicinal Chemistry, 22 (29), 3326-3346. doi: 10.2174/0929867322666150825162941

Endosome escape strategies for improving the efficacy of oligonucleotide delivery systems

2015

Journal Article

Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons

Rosli, Nurlina, Christie, Michelle, Moyle, Peter M. and Toth, Istvan (2015). Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons. Bioorganic & Medicinal Chemistry, 23 (10), 2470-2479. doi: 10.1016/j.bmc.2015.03.058

Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons

2014

Journal Article

Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity

Zaman, Mehfuz, Chandrudu, Saranya, Giddam, Ashwini K., Reiman, Jennifer, Skwarczynski, Mariusz, McPhun, Virginia, Moyle, Peter M., Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2014). Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity. Nanomedicine, 9 (17), 2613-2624. doi: 10.2217/NNM.14.190

Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity

2014

Journal Article

The contribution of non-human primate models to the development of human vaccines

Rivera-Hernandez, Tania, Carnathan, Diane G., Moyle, Peter M., Toth, Istvan, West, Nicholas P., Young, Paul L., Silvestri, Guido and Walker, Mark J. (2014). The contribution of non-human primate models to the development of human vaccines. Discovery Medicine, 18 (101), 313-322.

The contribution of non-human primate models to the development of human vaccines

2014

Journal Article

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

Ahmad Fuaad, Abdullah A. H., Jia, Zhongfan, Hartas, Jon, Ziora, Zyta M., Lin, I-Chun, Moyle, Peter M., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2014). Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine, 9 (1), 35-43. doi: 10.2217/NNM.13.7

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

2013

Journal Article

Synthesis and characterization of luteinizing hormone-releasing hormone (LHRH)-functionalized mini-dendrimers

Rafiee, Amirreza, Mansfeld, Friederike M., Moyle, Peter M. and Toth, Istvan (2013). Synthesis and characterization of luteinizing hormone-releasing hormone (LHRH)-functionalized mini-dendrimers. International Journal of Chemistry, 3 (1), 51-57. doi: 10.4236/ijoc.2013.31006

Synthesis and characterization of luteinizing hormone-releasing hormone (LHRH)-functionalized mini-dendrimers

2011

Journal Article

Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products

Simerska, Pavla, Moyle, Peter M. and Toth, Istvan (2011). Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products. Medicinal Research Reviews, 31 (4), 520-547. doi: 10.1002/med.20191

Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products

2010

Book Chapter

Lipopeptide-based vaccines

Jackson, David C., Chua, Brendon Y., Brown, Lorena E., Moyle, Peter and Toth, Istvan (2010). Lipopeptide-based vaccines. New generation vaccines. (pp. 315-326) edited by Myron M. Levine. New York, U.S.A.; London, U.K.: Informa Healthcare. doi: 10.3109/9781420060744-32

Lipopeptide-based vaccines

2009

Journal Article

Oral vaccine delivery - New strategies and technologies

Simerska, Pavla, Moyle, Peter M., Olive, Colleen and Toth, Istvan (2009). Oral vaccine delivery - New strategies and technologies. Current Drug Delivery, 6 (4), 347-358. doi: 10.2174/156720109789000537

Oral vaccine delivery - New strategies and technologies

2009

Book Chapter

Strategies in oral immunization

Simerska, Pavla, Moyle, Peter M., Olive, Colleen and Toth, Istvan (2009). Strategies in oral immunization. Oral Delivery of Macromolecular Drugs: Barriers, Strategies and Future Trends. (pp. 195-222) edited by Bernkop-Schnurch, Andreas. New York, United States: Springer. doi: 10.1007/978-1-4419-0200-9_11

Strategies in oral immunization

2009

Conference Publication

Vaccine delivery utilizing liposaccharides

Simerska, Pavla, McGeary, Ross P., Abdel-Aal, Abu-Baker M., Moyle, Peter M., Olive, Colleen, Good, Michael F. and Toth, Istvan (2009). Vaccine delivery utilizing liposaccharides. The 20th American Peptide Symposium, Montreal, Canada, 26-30 June, 2007. United States: Springer. doi: 10.1007/978-0-387-73657-0_153

Vaccine delivery utilizing liposaccharides

2009

Conference Publication

Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate

Toth, Istvan, Moyle, Peter M., Simerska, Pavla, Fujita, Yoshio, Olive, Colleen and Good, Michael F. (2009). Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate. 20th American Peptide Symposium, Montréal, Quebec, Canada, 26-30 June 2007. New York: Springer. doi: 10.1007/978-0-387-73657-0_154

Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate

2008

Journal Article

Development of a liposaccharide-based delivery system and its application to the design of Group A streptococcal vaccines

Simerska, Pavla, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Moyle, Peter M., McGeary, Ross P., Batzloff, Michael R., Olive, Colleen, Good, Michael F. and Toth, Istvan (2008). Development of a liposaccharide-based delivery system and its application to the design of Group A streptococcal vaccines. Journal of Medicinal Chemistry, 51 (5), 1447-1452. doi: 10.1021/jm701410p

Development of a liposaccharide-based delivery system and its application to the design of Group A streptococcal vaccines

2008

Journal Article

Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group A streptococcal vaccine candidates

Abdel-Aal, Abu-Baker M., Batzloff, Michael R., Fujita, Yoshio, Barozzi, Nadia, Faria, Andres, Simerska, Pavla, Moyle, Peter M., Good, Michael F. and Toth, Istvan (2008). Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group A streptococcal vaccine candidates. Journal of Medicinal Chemistry, 51 (1), 167-172. doi: 10.1021/jm701091d

Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group A streptococcal vaccine candidates