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2024

Journal Article

Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury

Wang, Xiangju, Kim, Chang Seong, Adams, Benjamin C., Wilkinson, Ray, Hill, Michelle M., Shah, Alok K., Mohamed, Ahmed, Dutt, Mriga, Ng, Monica S.Y., Ungerer, Jacobus P.J., Healy, Helen G. and Kassianos, Andrew J. (2024). Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury. Redox Biology, 70 103042, 103042. doi: 10.1016/j.redox.2024.103042

Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury

2023

Journal Article

High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints

Raghubar, Arti M., Matigian, Nicholas A., Crawford, Joanna, Francis, Leo, Ellis, Robert, Healy, Helen G., Kassianos, Andrew J., Ng, Monica S. Y., Roberts, Matthew J., Wood, Simon and Mallett, Andrew J. (2023). High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints. npj Precision Oncology, 7 (1) 88, 1-9. doi: 10.1038/s41698-023-00441-5

High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints

2022

Journal Article

Minimal change disease with Jack jumper ant stings: A case report

Tunbridge, Matthew, Grivei, Anca, Kassianos, Andrew J., Davis, Helen, Stewart, Anne, Healy, Helen, Mon, Saw Yu and John, George T. (2022). Minimal change disease with Jack jumper ant stings: A case report. Nephrology, 27 (11), 908-909. doi: 10.1111/nep.14104

Minimal change disease with Jack jumper ant stings: A case report

2022

Journal Article

Cellular milieu in clear cell renal cell carcinoma

Raghubar, Arti M., Roberts, Matthew J., Wood, Simon, Healy, Helen G., Kassianos, Andrew J. and Mallett, Andrew J. (2022). Cellular milieu in clear cell renal cell carcinoma. Frontiers in Oncology, 12 943583, 1-10. doi: 10.3389/fonc.2022.943583

Cellular milieu in clear cell renal cell carcinoma

2022

Journal Article

Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells

Giuliani, Kurt T. K., Grivei, Anca, Nag, Purba, Wang, Xiangju, Rist, Melissa, Kildey, Katrina, Law, Becker, Ng, Monica S., Wilkinson, Ray, Ungerer, Jacobus, Forbes, Josephine M., Healy, Helen and Kassianos, Andrew J. (2022). Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells. Cell Death and Disease, 13 (8) 739, 1-13. doi: 10.1038/s41419-022-05191-z

Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells

2022

Journal Article

Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments

Raghubar, Arti M., Pham, Duy T., Tan, Xiao, Grice, Laura F., Crawford, Joanna, Lam, Pui Yeng, Andersen, Stacey B., Yoon, Sohye, Teoh, Siok Min, Matigian, Nicholas A., Stewart, Anne, Francis, Leo, Ng, Monica S. Y., Healy, Helen G., Combes, Alexander N., Kassianos, Andrew J., Nguyen, Quan and Mallett, Andrew J. (2022). Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments. Frontiers in Medicine, 9 873923, 873923. doi: 10.3389/fmed.2022.873923

Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments

2022

Journal Article

Promoting plant-based therapies for chronic kidney disease

Khan, Muhammad Ali, Kassianos, Andrew J., Hoy, Wendy E., Alam, AHM Khurshid, Healy, Helen G. and Gobe, Glenda C. (2022). Promoting plant-based therapies for chronic kidney disease. Journal of Evidence-Based Integrative Medicine, 27 ARTN 2515690X221079688, 2515690X2210796. doi: 10.1177/2515690x221079688

Promoting plant-based therapies for chronic kidney disease

2022

Journal Article

SARS-CoV-2 vaccination–associated collapsing glomerulopathy in a kidney transplant recipient

Jefferis, Julia, Kassianos, Andrew J., Grivei, Anca, Doucet, Brian, Healy, Helen, Francis, Leo, Mon, Saw Yu and John, George T. (2022). SARS-CoV-2 vaccination–associated collapsing glomerulopathy in a kidney transplant recipient. Kidney International, 101 (3), 635-636. doi: 10.1016/j.kint.2021.12.018

SARS-CoV-2 vaccination–associated collapsing glomerulopathy in a kidney transplant recipient

2022

Journal Article

Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells

Khan, Muhammad Ali, Nag, Purba, Grivei, Anca, Giuliani, Kurt T. K., Wang, Xiangju, Diwan, Vishal, Hoy, Wendy, Healy, Helen, Gobe, Glenda and Kassianos, Andrew J. (2022). Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells. Cell Death and Disease, 13 (2) 104, 1-12. doi: 10.1038/s41419-022-04527-z

Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells

2021

Journal Article

T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes

Forbes, Josephine M., McCarthy, Domenica A., Kassianos, Andrew J., Baskerville, Tracey, Fotheringham, Amelia J., Giuliani, Kurt T. K., Grivei, Anca, Murphy, Andrew J., Flynn, Michelle C., Sullivan, Mitchell A., Chandrashekar, Preeti, Whiddett, Rani, Radford, Kristen J., Flemming, Nicole, Beard, Sam S., D’Silva, Neisha, Nisbet, Janelle, Morton, Adam, Teasdale, Stephanie, Russell, Anthony, Isbel, Nicole, Jones, Timothy, Couper, Jennifer, Healy, Helen, Harris, Mark, Donaghue, Kim, Johnson, David W., Cotterill, Andrew, Barrett, Helen L. and O’Moore-Sullivan, Trisha (2021). T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes. Diabetes, 70 (8), 1754-1766. doi: 10.2337/db20-1081

T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes

2021

Journal Article

Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

Wang, Xiangju, Wilkinson, Ray, Kildey, Katrina, Ungerer, Jacobus P. J., Hill, Michelle M., Shah, Alok K., Mohamed, Ahmed, Dutt, Mriga, Molendijk, Jeffrey, Healy, Helen and Kassianos, Andrew J. (2021). Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions. Journal of Extracellular Vesicles, 10 (4) e12064, e12064. doi: 10.1002/jev2.12064

Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

2020

Journal Article

Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury

Grivei, Anca, Giuliani, Kurt T.K., Wang, Xiangju, Ungerer, Jacobus, Francis, Leo, Hepburn, Kirsten, John, George T., Gois, Pedro F.H., Kassianos, Andrew J. and Healy, Helen (2020). Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury. Free Radical Biology and Medicine, 160, 690-695. doi: 10.1016/j.freeradbiomed.2020.09.011

Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury

2020

Journal Article

The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis

Hong, Seokchan, Healy, Helen and Kassianos, Andrew J. (2020). The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis. Frontiers in Immunology, 11 578952, 578952. doi: 10.3389/fimmu.2020.578952

The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis

2020

Journal Article

The role of inflammation and inflammasome activation in human bile cast nephropathy

Giuliani, Kurt T. K., Kassianos, Andrew J., Kildey, Katrina, Grivei, Anca, Wang, Xiangju, Ungerer, Jacobus, Francis, Leo, Healy, Helen and Gois, Pedro F. H. (2020). The role of inflammation and inflammasome activation in human bile cast nephropathy. Nephrology, 25 (6) nep.13696, 502-506. doi: 10.1111/nep.13696

The role of inflammation and inflammasome activation in human bile cast nephropathy

2020

Journal Article

Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells

Khan, Muhammad Ali, Wang, Xiangju, Giuliani, Kurt T. K., Nag, Purba, Grivei, Anca, Ungerer, Jacobus, Hoy, Wendy, Healy, Helen, Gobe, Glenda and Kassianos, Andrew J. (2020). Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells. International Journal of Molecular Sciences, 21 (2) 560, 1-15. doi: 10.3390/ijms21020560

Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells

2019

Journal Article

Specialized roles of human natural killer cell subsets in kidney transplant rejection

Kildey, Katrina, Francis, Ross S., Hultin, Sebastian, Harfield, Michelle, Giuliani, Kurt, Law, Becker M. P., Wang, Xiangju, See, Emily J., John, George, Ungerer, Jacobus, Wilkinson, Ray, Kassianos, Andrew J. and Healy, Helen (2019). Specialized roles of human natural killer cell subsets in kidney transplant rejection. Frontiers in Immunology, 10 (AUG) Article 1877, 1877. doi: 10.3389/fimmu.2019.01877

Specialized roles of human natural killer cell subsets in kidney transplant rejection

2019

Journal Article

Human tissue-resident mucosal-associated invariant T (MAIT) cells in renal fibrosis and CKD

Law, Becker M. P., Wilkinson, Ray, Wang, Xiangju, Kildey, Katrina, Giuliani, Kurt, Beagley, Kenneth W., Ungerer, Jacobus, Healy, Helen and Kassianos, Andrew J. (2019). Human tissue-resident mucosal-associated invariant T (MAIT) cells in renal fibrosis and CKD. Journal of the American Society of Nephrology, 30 (7), 1322-1335. doi: 10.1681/asn.2018101064

Human tissue-resident mucosal-associated invariant T (MAIT) cells in renal fibrosis and CKD

2019

Journal Article

Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease

Owens, Evan P., Vesey, David A., Kassianos, Andrew J., Healy, Helen, Hoy, Wendy E. and Gobe, Glenda C. (2019). Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease. Translational Andrology and Urology, 8 (S2), S175-S183. doi: 10.21037/tau.2018.11.03

Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease

2019

Journal Article

Pigment nephropathy: novel insights into inflammasome-mediated pathogenesis

Giuliani, Kurt T. K., Kassianos, Andrew J., Healy, Helen and Gois, Pedro H. F. (2019). Pigment nephropathy: novel insights into inflammasome-mediated pathogenesis. International Journal of Molecular Sciences, 20 (8) 1997, 1997. doi: 10.3390/ijms20081997

Pigment nephropathy: novel insights into inflammasome-mediated pathogenesis

2019

Journal Article

Natural killer cells in kidney health and disease

Turner, Jan-Eric, Rickassel, Constantin, Healy, Helen and Kassianos, Andrew J. (2019). Natural killer cells in kidney health and disease. Frontiers in Immunology, 10 (March) 587. doi: 10.3389/fimmu.2019.00587

Natural killer cells in kidney health and disease