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2025

Journal Article

Head-to-head comparison of tyrosine kinase inhibitors in renal cell carcinoma using patient-derived cell culture

Urquhart, Aaron J., Glass, Christian H., Humphries, Tyrone L. R., Kassianos, Andrew J., Vesey, David A., Wood, Simon T., Gobe, Glenda C. and Ellis, Robert J. (2025). Head-to-head comparison of tyrosine kinase inhibitors in renal cell carcinoma using patient-derived cell culture. Personalized Medicine, 22 (2), 83-91. doi: 10.1080/17410541.2025.2473303

Head-to-head comparison of tyrosine kinase inhibitors in renal cell carcinoma using patient-derived cell culture

2025

Journal Article

Urinary EGF : Back to the Future

Ng, Monica Suet Ying and Kassianos, Andrew J. (2025). Urinary EGF : Back to the Future. Kidney360, 6 (3), 348-350. doi: 10.34067/kid.0000000720

Urinary EGF : Back to the Future

2025

Journal Article

Metabolite pathway alterations identified by magnetic resonance metabolomics in a proximal tubular epithelial cell line treated with <scp>TGF</scp>‐β1

Humphries, Tyrone L. R., Lee, Soobin, Urquhart, Aaron J., Vesey, David A., Micallef, Aaron S., Winterford, Clay, Kassianos, Andrew J., Galloway, Graham J., Francis, Ross S. and Gobe, Glenda C. (2025). Metabolite pathway alterations identified by magnetic resonance metabolomics in a proximal tubular epithelial cell line treated with TGF‐β1. Physiological Reports, 13 (4) e70249. doi: 10.14814/phy2.70249

Metabolite pathway alterations identified by magnetic resonance metabolomics in a proximal tubular epithelial cell line treated with <scp>TGF</scp>‐β1

2025

Journal Article

Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury

Giuliani, Kurt T. K., Nag, Purba, Adams, Benjamin C., Wang, Xiangju, Hong, Seokchan, Grivei, Anca, Johnston, Rebecca L., Waddell, Nicola, Ho, Kenneth K. C., Tian, Yilin, Khan, Muhammad Ali, Kim, Chang Seong, Ng, Monica S. Y., Gobe, Glenda, Ungerer, Jacobus P. J., Forbes, Josephine M., Healy, Helen G. and Kassianos, Andrew J. (2025). Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury. Cell Death & Disease, 16 (1) 61, 61. doi: 10.1038/s41419-025-07386-6

Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury

2024

Journal Article

Fabry Disease Podocytes Reveal Ferroptosis as a Potential Regulator of Cell Pathology

Wise, Andrea F., Krisnadevi, IGAA Ari, Bruell, Shoni, Lee, Han-Chung, Bhuvan, Tejasvini, Kassianos, Andrew J., Saini, Sheetal, Wang, Xiangju, Healy, Helen G., Qian, Elizabeth Ling, Elliot, David A., Steele, Joel R, Fuller, Maria, Nicholls, Kathleen M. and Ricardo, Sharon D. (2024). Fabry Disease Podocytes Reveal Ferroptosis as a Potential Regulator of Cell Pathology. Kidney International Reports, 10 (2), 535-548. doi: 10.1016/j.ekir.2024.11.024

Fabry Disease Podocytes Reveal Ferroptosis as a Potential Regulator of Cell Pathology

2024

Journal Article

Regulated cell death in chronic kidney disease: current evidence and future clinical perspectives

Giuliani, Kurt T. K., Adams, Benjamin C., Healy, Helen G. and Kassianos, Andrew J. (2024). Regulated cell death in chronic kidney disease: current evidence and future clinical perspectives. Frontiers in Cell and Developmental Biology, 12 1497460. doi: 10.3389/fcell.2024.1497460

Regulated cell death in chronic kidney disease: current evidence and future clinical perspectives

2024

Journal Article

Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury

Wang, Xiangju, Kim, Chang Seong, Adams, Benjamin C., Wilkinson, Ray, Hill, Michelle M., Shah, Alok K., Mohamed, Ahmed, Dutt, Mriga, Ng, Monica S.Y., Ungerer, Jacobus P.J., Healy, Helen G. and Kassianos, Andrew J. (2024). Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury. Redox Biology, 70 103042, 1-13. doi: 10.1016/j.redox.2024.103042

Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury

2023

Journal Article

High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints

Raghubar, Arti M., Matigian, Nicholas A., Crawford, Joanna, Francis, Leo, Ellis, Robert, Healy, Helen G., Kassianos, Andrew J., Ng, Monica S. Y., Roberts, Matthew J., Wood, Simon and Mallett, Andrew J. (2023). High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints. npj Precision Oncology, 7 (1) 88, 1-9. doi: 10.1038/s41698-023-00441-5

High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints

2022

Journal Article

Minimal change disease with Jack jumper ant stings: A case report

Tunbridge, Matthew, Grivei, Anca, Kassianos, Andrew J., Davis, Helen, Stewart, Anne, Healy, Helen, Mon, Saw Yu and John, George T. (2022). Minimal change disease with Jack jumper ant stings: A case report. Nephrology, 27 (11), 908-909. doi: 10.1111/nep.14104

Minimal change disease with Jack jumper ant stings: A case report

2022

Journal Article

Cellular milieu in clear cell renal cell carcinoma

Raghubar, Arti M., Roberts, Matthew J., Wood, Simon, Healy, Helen G., Kassianos, Andrew J. and Mallett, Andrew J. (2022). Cellular milieu in clear cell renal cell carcinoma. Frontiers in Oncology, 12 943583, 1-10. doi: 10.3389/fonc.2022.943583

Cellular milieu in clear cell renal cell carcinoma

2022

Journal Article

Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells

Giuliani, Kurt T. K., Grivei, Anca, Nag, Purba, Wang, Xiangju, Rist, Melissa, Kildey, Katrina, Law, Becker, Ng, Monica S., Wilkinson, Ray, Ungerer, Jacobus, Forbes, Josephine M., Healy, Helen and Kassianos, Andrew J. (2022). Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells. Cell Death and Disease, 13 (8) 739, 1-13. doi: 10.1038/s41419-022-05191-z

Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells

2022

Journal Article

Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments

Raghubar, Arti M., Pham, Duy T., Tan, Xiao, Grice, Laura F., Crawford, Joanna, Lam, Pui Yeng, Andersen, Stacey B., Yoon, Sohye, Teoh, Siok Min, Matigian, Nicholas A., Stewart, Anne, Francis, Leo, Ng, Monica S. Y., Healy, Helen G., Combes, Alexander N., Kassianos, Andrew J., Nguyen, Quan and Mallett, Andrew J. (2022). Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments. Frontiers in Medicine, 9 873923, 873923. doi: 10.3389/fmed.2022.873923

Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments

2022

Journal Article

Promoting plant-based therapies for chronic kidney disease

Khan, Muhammad Ali, Kassianos, Andrew J., Hoy, Wendy E., Alam, AHM Khurshid, Healy, Helen G. and Gobe, Glenda C. (2022). Promoting plant-based therapies for chronic kidney disease. Journal of Evidence-Based Integrative Medicine, 27 2515690X221079688, 2515690X2210796. doi: 10.1177/2515690x221079688

Promoting plant-based therapies for chronic kidney disease

2022

Journal Article

SARS-CoV-2 vaccination–associated collapsing glomerulopathy in a kidney transplant recipient

Jefferis, Julia, Kassianos, Andrew J., Grivei, Anca, Doucet, Brian, Healy, Helen, Francis, Leo, Mon, Saw Yu and John, George T. (2022). SARS-CoV-2 vaccination–associated collapsing glomerulopathy in a kidney transplant recipient. Kidney International, 101 (3), 635-636. doi: 10.1016/j.kint.2021.12.018

SARS-CoV-2 vaccination–associated collapsing glomerulopathy in a kidney transplant recipient

2022

Journal Article

Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells

Khan, Muhammad Ali, Nag, Purba, Grivei, Anca, Giuliani, Kurt T. K., Wang, Xiangju, Diwan, Vishal, Hoy, Wendy, Healy, Helen, Gobe, Glenda and Kassianos, Andrew J. (2022). Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells. Cell Death and Disease, 13 (2) 104, 1-12. doi: 10.1038/s41419-022-04527-z

Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells

2021

Journal Article

T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes

Forbes, Josephine M., McCarthy, Domenica A., Kassianos, Andrew J., Baskerville, Tracey, Fotheringham, Amelia J., Giuliani, Kurt T. K., Grivei, Anca, Murphy, Andrew J., Flynn, Michelle C., Sullivan, Mitchell A., Chandrashekar, Preeti, Whiddett, Rani, Radford, Kristen J., Flemming, Nicole, Beard, Sam S., D’Silva, Neisha, Nisbet, Janelle, Morton, Adam, Teasdale, Stephanie, Russell, Anthony, Isbel, Nicole, Jones, Timothy, Couper, Jennifer, Healy, Helen, Harris, Mark, Donaghue, Kim, Johnson, David W., Cotterill, Andrew, Barrett, Helen L. and O’Moore-Sullivan, Trisha (2021). T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes. Diabetes, 70 (8), 1754-1766. doi: 10.2337/db20-1081

T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes

2021

Journal Article

Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

Wang, Xiangju, Wilkinson, Ray, Kildey, Katrina, Ungerer, Jacobus P. J., Hill, Michelle M., Shah, Alok K., Mohamed, Ahmed, Dutt, Mriga, Molendijk, Jeffrey, Healy, Helen and Kassianos, Andrew J. (2021). Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions. Journal of Extracellular Vesicles, 10 (4) e12064, e12064. doi: 10.1002/jev2.12064

Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

2020

Journal Article

Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury

Grivei, Anca, Giuliani, Kurt T.K., Wang, Xiangju, Ungerer, Jacobus, Francis, Leo, Hepburn, Kirsten, John, George T., Gois, Pedro F.H., Kassianos, Andrew J. and Healy, Helen (2020). Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury. Free Radical Biology and Medicine, 160, 690-695. doi: 10.1016/j.freeradbiomed.2020.09.011

Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury

2020

Journal Article

The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis

Hong, Seokchan, Healy, Helen and Kassianos, Andrew J. (2020). The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis. Frontiers in Immunology, 11 578952, 578952. doi: 10.3389/fimmu.2020.578952

The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis

2020

Journal Article

The role of inflammation and inflammasome activation in human bile cast nephropathy

Giuliani, Kurt T. K., Kassianos, Andrew J., Kildey, Katrina, Grivei, Anca, Wang, Xiangju, Ungerer, Jacobus, Francis, Leo, Healy, Helen and Gois, Pedro F. H. (2020). The role of inflammation and inflammasome activation in human bile cast nephropathy. Nephrology, 25 (6) nep.13696, 502-506. doi: 10.1111/nep.13696

The role of inflammation and inflammasome activation in human bile cast nephropathy