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2025

Journal Article

Counting glomeruli in human kidney specimens using ex vivo MRI without contrast agents

Kurniawan, Nyoman D., Amar, Aurel J., Cullen‐McEwen, Luise A., Combes, Alexander N., Hayatudin, Raeesah, Kassianos, Andrew J., Du, Jiaxin, Gazzard, Sarah E., Healy, Helen G., Hoy, Wendy E., Bertram, John F. and Reutens, David C. (2025). Counting glomeruli in human kidney specimens using ex vivo MRI without contrast agents. Magnetic Resonance in Medicine mrm.30642. doi: 10.1002/mrm.30642

Counting glomeruli in human kidney specimens using ex vivo MRI without contrast agents

2025

Conference Publication

Automated 3D segmentation of glomeruli in human kidney tissue specimens using 16.4 T MRI without contrast agents

Amar, Aurel J., Kurniawan, Nyoman D., Cullen-McEwen, Luise A., Kassianos, Andrew J., Healy, Helen G., Bertram, John F., Chandra, Shekhar S. and Reutens, David C. (2025). Automated 3D segmentation of glomeruli in human kidney tissue specimens using 16.4 T MRI without contrast agents. 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI), Houston, TX, United States, 14-17 April 2025. Piscataway, NJ, United States: IEEE. doi: 10.1109/isbi60581.2025.10980815

Automated 3D segmentation of glomeruli in human kidney tissue specimens using 16.4 T MRI without contrast agents

2025

Journal Article

Head-to-head comparison of tyrosine kinase inhibitors in renal cell carcinoma using patient-derived cell culture

Urquhart, Aaron J., Glass, Christian H., Humphries, Tyrone L. R., Kassianos, Andrew J., Vesey, David A., Wood, Simon T., Gobe, Glenda C. and Ellis, Robert J. (2025). Head-to-head comparison of tyrosine kinase inhibitors in renal cell carcinoma using patient-derived cell culture. Personalized Medicine, 22 (2), 83-91. doi: 10.1080/17410541.2025.2473303

Head-to-head comparison of tyrosine kinase inhibitors in renal cell carcinoma using patient-derived cell culture

2025

Journal Article

Urinary EGF : Back to the Future

Ng, Monica Suet Ying and Kassianos, Andrew J. (2025). Urinary EGF : Back to the Future. Kidney360, 6 (3), 348-350. doi: 10.34067/kid.0000000720

Urinary EGF : Back to the Future

2025

Journal Article

Universal Paediatric and Newborn Screening for Familial Hypercholesterolaemia—Challenges and Opportunities: An Australian Perspective

Bachmeier, Caroline, Ungerer, Jacobus, Pretorius, Carel, Kassianos, Andrew and Kostner, Karam M. (2025). Universal Paediatric and Newborn Screening for Familial Hypercholesterolaemia—Challenges and Opportunities: An Australian Perspective. Lipidology, 2 (1), 4. doi: 10.3390/lipidology2010004

Universal Paediatric and Newborn Screening for Familial Hypercholesterolaemia—Challenges and Opportunities: An Australian Perspective

2025

Journal Article

Metabolite pathway alterations identified by magnetic resonance metabolomics in a proximal tubular epithelial cell line treated with <scp>TGF</scp>‐β1

Humphries, Tyrone L. R., Lee, Soobin, Urquhart, Aaron J., Vesey, David A., Micallef, Aaron S., Winterford, Clay, Kassianos, Andrew J., Galloway, Graham J., Francis, Ross S. and Gobe, Glenda C. (2025). Metabolite pathway alterations identified by magnetic resonance metabolomics in a proximal tubular epithelial cell line treated with TGF‐β1. Physiological Reports, 13 (4) e70249, e70249. doi: 10.14814/phy2.70249

Metabolite pathway alterations identified by magnetic resonance metabolomics in a proximal tubular epithelial cell line treated with <scp>TGF</scp>‐β1

2025

Journal Article

Fabry disease podocytes reveal ferroptosis as a potential regulator of cell pathology

Wise, Andrea F., Krisnadevi, IGAA Ari, Bruell, Shoni, Lee, Han-Chung, Bhuvan, Tejasvini, Kassianos, Andrew J., Saini, Sheetal, Wang, Xiangju, Healy, Helen G., Qian, Elizabeth Ling, Elliot, David A., Steele, Joel R, Fuller, Maria, Nicholls, Kathleen M. and Ricardo, Sharon D. (2025). Fabry disease podocytes reveal ferroptosis as a potential regulator of cell pathology. Kidney International Reports, 10 (2), 535-548. doi: 10.1016/j.ekir.2024.11.024

Fabry disease podocytes reveal ferroptosis as a potential regulator of cell pathology

2025

Journal Article

Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury

Giuliani, Kurt T. K., Nag, Purba, Adams, Benjamin C., Wang, Xiangju, Hong, Seokchan, Grivei, Anca, Johnston, Rebecca L., Waddell, Nicola, Ho, Kenneth K. C., Tian, Yilin, Khan, Muhammad Ali, Kim, Chang Seong, Ng, Monica S. Y., Gobe, Glenda, Ungerer, Jacobus P. J., Forbes, Josephine M., Healy, Helen G. and Kassianos, Andrew J. (2025). Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury. Cell Death & Disease, 16 (1) 61, 61. doi: 10.1038/s41419-025-07386-6

Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury

2024

Journal Article

Regulated cell death in chronic kidney disease: current evidence and future clinical perspectives

Giuliani, Kurt T. K., Adams, Benjamin C., Healy, Helen G. and Kassianos, Andrew J. (2024). Regulated cell death in chronic kidney disease: current evidence and future clinical perspectives. Frontiers in Cell and Developmental Biology, 12 1497460, 1497460. doi: 10.3389/fcell.2024.1497460

Regulated cell death in chronic kidney disease: current evidence and future clinical perspectives

2024

Conference Publication

Progressive Changes in Urine Extracellular Vesicle Molecular Signatures Predict Phase of AKI

Ng, Monica S., Chiang, Sophie Chin-Ya, Wang, Xiangju, Healy, Helen G. and Kassianos, Andrew J. (2024). Progressive Changes in Urine Extracellular Vesicle Molecular Signatures Predict Phase of AKI. Kidney Week, San Diego, CA United States, 24-27 October 2024. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1681/asn.20242q4s6d94

Progressive Changes in Urine Extracellular Vesicle Molecular Signatures Predict Phase of AKI

2024

Conference Publication

Young Investigator Award - Discovery &amp; Translational Science

Adams, Benjamin, Kim, Chang Seong, Wang, Xiangju, Nguyen, Quan, Xiong, Zherui, Hockey, Levi, Ng, Monica Suet Ying, Healy, Helen and Kassianos, Andrew (2024). Young Investigator Award - Discovery &amp; Translational Science. 59th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Adelaide, SA Australia, 31 August–4 September 2024. Richmond, VIC Australia: John Wiley & Sons.

Young Investigator Award - Discovery &amp; Translational Science

2024

Conference Publication

Urinary Extracellular Vesicles As Prognostic Biomarkers Of Tubular Ferroptosis In Acute Kidney Injury Progression

Kassianos, Andrew, Kim, Chang Seong, Adams, Benjamin, Ng, Monica Suet Ying and Healy, Helen (2024). Urinary Extracellular Vesicles As Prognostic Biomarkers Of Tubular Ferroptosis In Acute Kidney Injury Progression. 59th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Adelaide, SA Australia, 31 August - 4 September 2024. Richmond, VIC Australia: John Wiley & Sons.

Urinary Extracellular Vesicles As Prognostic Biomarkers Of Tubular Ferroptosis In Acute Kidney Injury Progression

2024

Journal Article

Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury

Wang, Xiangju, Kim, Chang Seong, Adams, Benjamin C., Wilkinson, Ray, Hill, Michelle M., Shah, Alok K., Mohamed, Ahmed, Dutt, Mriga, Ng, Monica S.Y., Ungerer, Jacobus P.J., Healy, Helen G. and Kassianos, Andrew J. (2024). Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury. Redox Biology, 70 103042, 1-13. doi: 10.1016/j.redox.2024.103042

Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury

2024

Book Chapter

Nephron Senescence and Mechanisms

Healy, Helen, Kassianos, Andrew J., Ng, Monica S. Y. and O’Sullivan, Eoin D. (2024). Nephron Senescence and Mechanisms. Kidney Disease in the Elderly. (pp. 25-41) Cham, Switzerland: Springer. doi: 10.1007/978-3-031-68460-9_3

Nephron Senescence and Mechanisms

2023

Journal Article

High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints

Raghubar, Arti M., Matigian, Nicholas A., Crawford, Joanna, Francis, Leo, Ellis, Robert, Healy, Helen G., Kassianos, Andrew J., Ng, Monica S. Y., Roberts, Matthew J., Wood, Simon and Mallett, Andrew J. (2023). High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints. npj Precision Oncology, 7 (1) 88, 1-9. doi: 10.1038/s41698-023-00441-5

High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints

2023

Conference Publication

Hypoxia and interleukin (IL)-1β synergistically induce cellular senescence in human proximal tubular epithelial cells (PTEC)

Kassianos, Andrew J., Giuliani, Kurt, Nag, Purba, Hong, Seokchan, Wang, Xiangju, Johnston, Rebecca L., Adams, Benjamin, Grivei, Anca, Ho, Kenneth, Ng, Monica, Waddell, Nicola, Forbes, Josephine M., Healy, Helen and Kassianos, Andrew J. (2023). Hypoxia and interleukin (IL)-1β synergistically induce cellular senescence in human proximal tubular epithelial cells (PTEC). 58th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Christchurch, New Zealand, 4-6 September 2023. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/nep.14216

Hypoxia and interleukin (IL)-1β synergistically induce cellular senescence in human proximal tubular epithelial cells (PTEC)

2023

Book Chapter

Spatial transcriptomics in kidney tissue

Raghubar, Arti M., Crawford, Joanna, Jones, Kahli, Lam, Pui Y., Andersen, Stacey B., Matigian, Nicholas A., Ng, Monica S Y, Healy, Helen, Kassianos, Andrew J. and Mallett, Andrew J. (2023). Spatial transcriptomics in kidney tissue. Kidney research: experimental protocols. (pp. 233-282) edited by Tim D. Hewitson, Nigel D. Toussaint and Edward R. Smith. New York, NY USA: Humana New York. doi: 10.1007/978-1-0716-3179-9_17

Spatial transcriptomics in kidney tissue

2022

Journal Article

Minimal change disease with Jack jumper ant stings: A case report

Tunbridge, Matthew, Grivei, Anca, Kassianos, Andrew J., Davis, Helen, Stewart, Anne, Healy, Helen, Mon, Saw Yu and John, George T. (2022). Minimal change disease with Jack jumper ant stings: A case report. Nephrology, 27 (11), 908-909. doi: 10.1111/nep.14104

Minimal change disease with Jack jumper ant stings: A case report

2022

Journal Article

Cellular milieu in clear cell renal cell carcinoma

Raghubar, Arti M., Roberts, Matthew J., Wood, Simon, Healy, Helen G., Kassianos, Andrew J. and Mallett, Andrew J. (2022). Cellular milieu in clear cell renal cell carcinoma. Frontiers in Oncology, 12 943583, 1-10. doi: 10.3389/fonc.2022.943583

Cellular milieu in clear cell renal cell carcinoma

2022

Journal Article

Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells

Giuliani, Kurt T. K., Grivei, Anca, Nag, Purba, Wang, Xiangju, Rist, Melissa, Kildey, Katrina, Law, Becker, Ng, Monica S., Wilkinson, Ray, Ungerer, Jacobus, Forbes, Josephine M., Healy, Helen and Kassianos, Andrew J. (2022). Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells. Cell Death and Disease, 13 (8) 739, 1-13. doi: 10.1038/s41419-022-05191-z

Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells