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2021

Journal Article

Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

Wang, Xiangju, Wilkinson, Ray, Kildey, Katrina, Ungerer, Jacobus P. J., Hill, Michelle M., Shah, Alok K., Mohamed, Ahmed, Dutt, Mriga, Molendijk, Jeffrey, Healy, Helen and Kassianos, Andrew J. (2021). Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions. Journal of Extracellular Vesicles, 10 (4) e12064, e12064. doi: 10.1002/jev2.12064

Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

2020

Journal Article

Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury

Grivei, Anca, Giuliani, Kurt T.K., Wang, Xiangju, Ungerer, Jacobus, Francis, Leo, Hepburn, Kirsten, John, George T., Gois, Pedro F.H., Kassianos, Andrew J. and Healy, Helen (2020). Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury. Free Radical Biology and Medicine, 160, 690-695. doi: 10.1016/j.freeradbiomed.2020.09.011

Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury

2020

Conference Publication

Spatial Transcriptomics (ST): Integrating Molecular Profiles with Histomorphology in Kidney Tissue Sections

Raghubar, Arti M., Pham, Duy T., Tan, Xiao, Grice, Laura F., Lam, Pui Yeng, Crawford, Joanna, Andersen, Stacey, Yoon, Sohye, Holland, Samuel E., Francis, Leo, Combes, Alexander N., Kassianos, Andrew J., Healy, Helen G., Nguyen, Quan and Mallett, Andrew J. (2020). Spatial Transcriptomics (ST): Integrating Molecular Profiles with Histomorphology in Kidney Tissue Sections. Kidney Week, Online, 19-25 October 2020. Washington, DC United States: American Society of Nephrology. doi: 10.1681/asn.20203110s112b

Spatial Transcriptomics (ST): Integrating Molecular Profiles with Histomorphology in Kidney Tissue Sections

2020

Journal Article

The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis

Hong, Seokchan, Healy, Helen and Kassianos, Andrew J. (2020). The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis. Frontiers in Immunology, 11 578952, 578952. doi: 10.3389/fimmu.2020.578952

The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis

2020

Journal Article

The role of inflammation and inflammasome activation in human bile cast nephropathy

Giuliani, Kurt T. K., Kassianos, Andrew J., Kildey, Katrina, Grivei, Anca, Wang, Xiangju, Ungerer, Jacobus, Francis, Leo, Healy, Helen and Gois, Pedro F. H. (2020). The role of inflammation and inflammasome activation in human bile cast nephropathy. Nephrology, 25 (6) nep.13696, 502-506. doi: 10.1111/nep.13696

The role of inflammation and inflammasome activation in human bile cast nephropathy

2020

Journal Article

Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells

Khan, Muhammad Ali, Wang, Xiangju, Giuliani, Kurt T. K., Nag, Purba, Grivei, Anca, Ungerer, Jacobus, Hoy, Wendy, Healy, Helen, Gobe, Glenda and Kassianos, Andrew J. (2020). Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells. International Journal of Molecular Sciences, 21 (2) 560, 1-15. doi: 10.3390/ijms21020560

Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells

2019

Journal Article

Specialized roles of human natural killer cell subsets in kidney transplant rejection

Kildey, Katrina, Francis, Ross S., Hultin, Sebastian, Harfield, Michelle, Giuliani, Kurt, Law, Becker M. P., Wang, Xiangju, See, Emily J., John, George, Ungerer, Jacobus, Wilkinson, Ray, Kassianos, Andrew J. and Healy, Helen (2019). Specialized roles of human natural killer cell subsets in kidney transplant rejection. Frontiers in Immunology, 10 (AUG) Article 1877, 1877. doi: 10.3389/fimmu.2019.01877

Specialized roles of human natural killer cell subsets in kidney transplant rejection

2019

Journal Article

Human tissue-resident mucosal-associated invariant T (MAIT) cells in renal fibrosis and CKD

Law, Becker M. P., Wilkinson, Ray, Wang, Xiangju, Kildey, Katrina, Giuliani, Kurt, Beagley, Kenneth W., Ungerer, Jacobus, Healy, Helen and Kassianos, Andrew J. (2019). Human tissue-resident mucosal-associated invariant T (MAIT) cells in renal fibrosis and CKD. Journal of the American Society of Nephrology, 30 (7), 1322-1335. doi: 10.1681/asn.2018101064

Human tissue-resident mucosal-associated invariant T (MAIT) cells in renal fibrosis and CKD

2019

Journal Article

Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease

Owens, Evan P., Vesey, David A., Kassianos, Andrew J., Healy, Helen, Hoy, Wendy E. and Gobe, Glenda C. (2019). Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease. Translational Andrology and Urology, 8 (S2), S175-S183. doi: 10.21037/tau.2018.11.03

Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease

2019

Journal Article

Pigment nephropathy: novel insights into inflammasome-mediated pathogenesis

Giuliani, Kurt T. K., Kassianos, Andrew J., Healy, Helen and Gois, Pedro H. F. (2019). Pigment nephropathy: novel insights into inflammasome-mediated pathogenesis. International Journal of Molecular Sciences, 20 (8) 1997, 1997. doi: 10.3390/ijms20081997

Pigment nephropathy: novel insights into inflammasome-mediated pathogenesis

2019

Journal Article

Natural killer cells in kidney health and disease

Turner, Jan-Eric, Rickassel, Constantin, Healy, Helen and Kassianos, Andrew J. (2019). Natural killer cells in kidney health and disease. Frontiers in Immunology, 10 (March) 587. doi: 10.3389/fimmu.2019.00587

Natural killer cells in kidney health and disease

2018

Journal Article

The role of oxidative stress and inflammation in acute oxalate nephropathy associated with ethylene glycol intoxication

Wilson, Gregory J., Gois, Pedro H.F., Zhang, Alice, Wang, Xiangju, Law, Becker M.P., Kassianos, Andrew J. and Healy, Helen G. (2018). The role of oxidative stress and inflammation in acute oxalate nephropathy associated with ethylene glycol intoxication. Kidney International Reports, 3 (5), 1217-1221. doi: 10.1016/j.ekir.2018.05.005

The role of oxidative stress and inflammation in acute oxalate nephropathy associated with ethylene glycol intoxication

2018

Journal Article

Identification and quantitation of leukocyte populations in human kidney tissue by multi-parameter flow cytometry

Kildey, Katrina, Law, Becker M. P., Muczynski, Kimberly A., Wilkinson, Ray, Healy, Helen and Kassianos, Andrew J. (2018). Identification and quantitation of leukocyte populations in human kidney tissue by multi-parameter flow cytometry. Bio-Protocol, 8 (16) e2980, e2980. doi: 10.21769/BioProtoc.2980

Identification and quantitation of leukocyte populations in human kidney tissue by multi-parameter flow cytometry

2018

Journal Article

Effector γδ T cells in human renal fibrosis and chronic kidney disease

Law, Becker Meng-Po, Wilkinson, Ray, Wang, Xiangju, Kildey, Katrina, Lindner, Mae, Beagley, Kenneth, Healy, Helen and Kassianos, Andrew J. (2018). Effector γδ T cells in human renal fibrosis and chronic kidney disease. Nephrology, Dialysis, Transplantation, 34 (1), 40-48. doi: 10.1093/ndt/gfy098

Effector γδ T cells in human renal fibrosis and chronic kidney disease

2017

Journal Article

Interferon-γ production by tubulointerstitial human CD56bright natural killer cells contributes to renal fibrosis and chronic kidney disease progression

Law, Becker M. P., Wilkinson, Ray, Wang, Xiangju, Kildey, Katrina, Lindner, Mae, Rist, Melissa J., Beagley, Kenneth, Healy, Helen and Kassianos, Andrew J. (2017). Interferon-γ production by tubulointerstitial human CD56bright natural killer cells contributes to renal fibrosis and chronic kidney disease progression. Kidney International, 92 (1), 79-88. doi: 10.1016/j.kint.2017.02.006

Interferon-γ production by tubulointerstitial human CD56bright natural killer cells contributes to renal fibrosis and chronic kidney disease progression

2017

Journal Article

Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions

Wang, Xiangju, Wilkinson, Ray, Kildey, Katrina, Potriquet, Jeremy, Mulvenna, Jason, Lobb, Richard J., Moller, Andreas, Cloonan, Nicole, Mukhopadhyay, Pamela, Kassianos, Andrew J. and Healy, Helen (2017). Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions. Journal of Extracellular Vesicles, 6 (1) 1314073, 1314073-1314073. doi: 10.1080/20013078.2017.1314073

Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions

2015

Journal Article

Human proximal tubule epithelial cells modulate autologous B-cell function

Sampangi, Sandeep, Wang, Xiangju, Beagley, Kenneth W., Klein, Travis, Afrin, Sadia, Healy, Helen, Wilkinson, Ray and Kassianos, Andrew J. (2015). Human proximal tubule epithelial cells modulate autologous B-cell function. Nephrology Dialysis Transplantation, 30 (10), 1674-1683. doi: 10.1093/ndt/gfv242

Human proximal tubule epithelial cells modulate autologous B-cell function

2015

Journal Article

The mechanisms of human renal epithelial cell modulation of autologous dendritic cell phenotype and function

Sampangi, Sandeep, Kassianos, Andrew J., Wang, Xiangju, Beagley, Kenneth W., Klein, Travis, Afrin, Sadia, Healy, Helen and Wilkinson, Ray (2015). The mechanisms of human renal epithelial cell modulation of autologous dendritic cell phenotype and function. PLoS One, 10 (7) e0134688, e0134688. doi: 10.1371/journal.pone.0134688

The mechanisms of human renal epithelial cell modulation of autologous dendritic cell phenotype and function

2015

Journal Article

Fractalkine-CX3CR1-dependent recruitment and retention of human CD1c+ myeloid dendritic cells by in vitro-activated proximal tubular epithelial cells

Kassianos, Andrew J., Wang, Xiangju, Sampang, Sandeep, Afrin, Sadia, Wilkinson, Ray and Healy, Helen (2015). Fractalkine-CX3CR1-dependent recruitment and retention of human CD1c+ myeloid dendritic cells by in vitro-activated proximal tubular epithelial cells. Kidney International, 87 (6), 1153-1163. doi: 10.1038/ki.2014.407

Fractalkine-CX3CR1-dependent recruitment and retention of human CD1c+ myeloid dendritic cells by in vitro-activated proximal tubular epithelial cells

2015

Journal Article

Differential uptake and cross-presentation of soluble and necrotic cell antigen by human DC subsets

Chiang, Meng-Chieh, Tullett, Kirsteen M., Lee, Yoke Seng, Idris, Adi, Ding, Yitian, McDonald, Kylie J., Kassianos, Andrew, Leal Rojas, Ingrid M., Jeet, Varinder, Lahoud, Mireille H. and Radford, Kristen J. (2015). Differential uptake and cross-presentation of soluble and necrotic cell antigen by human DC subsets. European Journal of Immunology, 46 (2), 329-339. doi: 10.1002/eji.201546023

Differential uptake and cross-presentation of soluble and necrotic cell antigen by human DC subsets