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2022

Journal Article

Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments

Raghubar, Arti M., Pham, Duy T., Tan, Xiao, Grice, Laura F., Crawford, Joanna, Lam, Pui Yeng, Andersen, Stacey B., Yoon, Sohye, Teoh, Siok Min, Matigian, Nicholas A., Stewart, Anne, Francis, Leo, Ng, Monica S. Y., Healy, Helen G., Combes, Alexander N., Kassianos, Andrew J., Nguyen, Quan and Mallett, Andrew J. (2022). Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments. Frontiers in Medicine, 9 873923, 873923. doi: 10.3389/fmed.2022.873923

Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments

2022

Journal Article

Promoting plant-based therapies for chronic kidney disease

Khan, Muhammad Ali, Kassianos, Andrew J., Hoy, Wendy E., Alam, AHM Khurshid, Healy, Helen G. and Gobe, Glenda C. (2022). Promoting plant-based therapies for chronic kidney disease. Journal of Evidence-Based Integrative Medicine, 27 2515690X221079688, 2515690X2210796. doi: 10.1177/2515690x221079688

Promoting plant-based therapies for chronic kidney disease

2022

Journal Article

SARS-CoV-2 vaccination–associated collapsing glomerulopathy in a kidney transplant recipient

Jefferis, Julia, Kassianos, Andrew J., Grivei, Anca, Doucet, Brian, Healy, Helen, Francis, Leo, Mon, Saw Yu and John, George T. (2022). SARS-CoV-2 vaccination–associated collapsing glomerulopathy in a kidney transplant recipient. Kidney International, 101 (3), 635-636. doi: 10.1016/j.kint.2021.12.018

SARS-CoV-2 vaccination–associated collapsing glomerulopathy in a kidney transplant recipient

2022

Journal Article

Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells

Khan, Muhammad Ali, Nag, Purba, Grivei, Anca, Giuliani, Kurt T. K., Wang, Xiangju, Diwan, Vishal, Hoy, Wendy, Healy, Helen, Gobe, Glenda and Kassianos, Andrew J. (2022). Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells. Cell Death and Disease, 13 (2) 104, 1-12. doi: 10.1038/s41419-022-04527-z

Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells

2021

Journal Article

T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes

Forbes, Josephine M., McCarthy, Domenica A., Kassianos, Andrew J., Baskerville, Tracey, Fotheringham, Amelia J., Giuliani, Kurt T. K., Grivei, Anca, Murphy, Andrew J., Flynn, Michelle C., Sullivan, Mitchell A., Chandrashekar, Preeti, Whiddett, Rani, Radford, Kristen J., Flemming, Nicole, Beard, Sam S., D’Silva, Neisha, Nisbet, Janelle, Morton, Adam, Teasdale, Stephanie, Russell, Anthony, Isbel, Nicole, Jones, Timothy, Couper, Jennifer, Healy, Helen, Harris, Mark, Donaghue, Kim, Johnson, David W., Cotterill, Andrew, Barrett, Helen L. and O’Moore-Sullivan, Trisha (2021). T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes. Diabetes, 70 (8), 1754-1766. doi: 10.2337/db20-1081

T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes

2021

Journal Article

Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

Wang, Xiangju, Wilkinson, Ray, Kildey, Katrina, Ungerer, Jacobus P. J., Hill, Michelle M., Shah, Alok K., Mohamed, Ahmed, Dutt, Mriga, Molendijk, Jeffrey, Healy, Helen and Kassianos, Andrew J. (2021). Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions. Journal of Extracellular Vesicles, 10 (4) e12064, e12064. doi: 10.1002/jev2.12064

Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

2020

Journal Article

Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury

Grivei, Anca, Giuliani, Kurt T.K., Wang, Xiangju, Ungerer, Jacobus, Francis, Leo, Hepburn, Kirsten, John, George T., Gois, Pedro F.H., Kassianos, Andrew J. and Healy, Helen (2020). Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury. Free Radical Biology and Medicine, 160, 690-695. doi: 10.1016/j.freeradbiomed.2020.09.011

Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury

2020

Conference Publication

Spatial Transcriptomics (ST): Integrating Molecular Profiles with Histomorphology in Kidney Tissue Sections

Raghubar, Arti M., Pham, Duy T., Tan, Xiao, Grice, Laura F., Lam, Pui Yeng, Crawford, Joanna, Andersen, Stacey, Yoon, Sohye, Holland, Samuel E., Francis, Leo, Combes, Alexander N., Kassianos, Andrew J., Healy, Helen G., Nguyen, Quan and Mallett, Andrew J. (2020). Spatial Transcriptomics (ST): Integrating Molecular Profiles with Histomorphology in Kidney Tissue Sections. Kidney Week, Online, 19-25 October 2020. Washington, DC United States: American Society of Nephrology. doi: 10.1681/asn.20203110s112b

Spatial Transcriptomics (ST): Integrating Molecular Profiles with Histomorphology in Kidney Tissue Sections

2020

Journal Article

The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis

Hong, Seokchan, Healy, Helen and Kassianos, Andrew J. (2020). The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis. Frontiers in Immunology, 11 578952, 578952. doi: 10.3389/fimmu.2020.578952

The emerging role of renal tubular epithelial cells in the immunological pathophysiology of lupus nephritis

2020

Journal Article

The role of inflammation and inflammasome activation in human bile cast nephropathy

Giuliani, Kurt T. K., Kassianos, Andrew J., Kildey, Katrina, Grivei, Anca, Wang, Xiangju, Ungerer, Jacobus, Francis, Leo, Healy, Helen and Gois, Pedro F. H. (2020). The role of inflammation and inflammasome activation in human bile cast nephropathy. Nephrology, 25 (6) nep.13696, 502-506. doi: 10.1111/nep.13696

The role of inflammation and inflammasome activation in human bile cast nephropathy

2020

Journal Article

Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells

Khan, Muhammad Ali, Wang, Xiangju, Giuliani, Kurt T. K., Nag, Purba, Grivei, Anca, Ungerer, Jacobus, Hoy, Wendy, Healy, Helen, Gobe, Glenda and Kassianos, Andrew J. (2020). Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells. International Journal of Molecular Sciences, 21 (2) 560, 1-15. doi: 10.3390/ijms21020560

Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells

2019

Journal Article

Specialized roles of human natural killer cell subsets in kidney transplant rejection

Kildey, Katrina, Francis, Ross S., Hultin, Sebastian, Harfield, Michelle, Giuliani, Kurt, Law, Becker M. P., Wang, Xiangju, See, Emily J., John, George, Ungerer, Jacobus, Wilkinson, Ray, Kassianos, Andrew J. and Healy, Helen (2019). Specialized roles of human natural killer cell subsets in kidney transplant rejection. Frontiers in Immunology, 10 (AUG) Article 1877, 1877. doi: 10.3389/fimmu.2019.01877

Specialized roles of human natural killer cell subsets in kidney transplant rejection

2019

Journal Article

Human tissue-resident mucosal-associated invariant T (MAIT) cells in renal fibrosis and CKD

Law, Becker M. P., Wilkinson, Ray, Wang, Xiangju, Kildey, Katrina, Giuliani, Kurt, Beagley, Kenneth W., Ungerer, Jacobus, Healy, Helen and Kassianos, Andrew J. (2019). Human tissue-resident mucosal-associated invariant T (MAIT) cells in renal fibrosis and CKD. Journal of the American Society of Nephrology, 30 (7), 1322-1335. doi: 10.1681/asn.2018101064

Human tissue-resident mucosal-associated invariant T (MAIT) cells in renal fibrosis and CKD

2019

Journal Article

Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease

Owens, Evan P., Vesey, David A., Kassianos, Andrew J., Healy, Helen, Hoy, Wendy E. and Gobe, Glenda C. (2019). Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease. Translational Andrology and Urology, 8 (S2), S175-S183. doi: 10.21037/tau.2018.11.03

Biomarkers and the role of mast cells as facilitators of inflammation and fibrosis in chronic kidney disease

2019

Journal Article

Pigment nephropathy: novel insights into inflammasome-mediated pathogenesis

Giuliani, Kurt T. K., Kassianos, Andrew J., Healy, Helen and Gois, Pedro H. F. (2019). Pigment nephropathy: novel insights into inflammasome-mediated pathogenesis. International Journal of Molecular Sciences, 20 (8) 1997, 1997. doi: 10.3390/ijms20081997

Pigment nephropathy: novel insights into inflammasome-mediated pathogenesis

2019

Journal Article

Natural killer cells in kidney health and disease

Turner, Jan-Eric, Rickassel, Constantin, Healy, Helen and Kassianos, Andrew J. (2019). Natural killer cells in kidney health and disease. Frontiers in Immunology, 10 (March) 587. doi: 10.3389/fimmu.2019.00587

Natural killer cells in kidney health and disease

2018

Journal Article

The role of oxidative stress and inflammation in acute oxalate nephropathy associated with ethylene glycol intoxication

Wilson, Gregory J., Gois, Pedro H.F., Zhang, Alice, Wang, Xiangju, Law, Becker M.P., Kassianos, Andrew J. and Healy, Helen G. (2018). The role of oxidative stress and inflammation in acute oxalate nephropathy associated with ethylene glycol intoxication. Kidney International Reports, 3 (5), 1217-1221. doi: 10.1016/j.ekir.2018.05.005

The role of oxidative stress and inflammation in acute oxalate nephropathy associated with ethylene glycol intoxication

2018

Journal Article

Identification and quantitation of leukocyte populations in human kidney tissue by multi-parameter flow cytometry

Kildey, Katrina, Law, Becker M. P., Muczynski, Kimberly A., Wilkinson, Ray, Healy, Helen and Kassianos, Andrew J. (2018). Identification and quantitation of leukocyte populations in human kidney tissue by multi-parameter flow cytometry. Bio-Protocol, 8 (16) e2980, e2980. doi: 10.21769/BioProtoc.2980

Identification and quantitation of leukocyte populations in human kidney tissue by multi-parameter flow cytometry

2018

Journal Article

Effector γδ T cells in human renal fibrosis and chronic kidney disease

Law, Becker Meng-Po, Wilkinson, Ray, Wang, Xiangju, Kildey, Katrina, Lindner, Mae, Beagley, Kenneth, Healy, Helen and Kassianos, Andrew J. (2018). Effector γδ T cells in human renal fibrosis and chronic kidney disease. Nephrology, Dialysis, Transplantation, 34 (1), 40-48. doi: 10.1093/ndt/gfy098

Effector γδ T cells in human renal fibrosis and chronic kidney disease

2017

Journal Article

Interferon-γ production by tubulointerstitial human CD56bright natural killer cells contributes to renal fibrosis and chronic kidney disease progression

Law, Becker M. P., Wilkinson, Ray, Wang, Xiangju, Kildey, Katrina, Lindner, Mae, Rist, Melissa J., Beagley, Kenneth, Healy, Helen and Kassianos, Andrew J. (2017). Interferon-γ production by tubulointerstitial human CD56bright natural killer cells contributes to renal fibrosis and chronic kidney disease progression. Kidney International, 92 (1), 79-88. doi: 10.1016/j.kint.2017.02.006

Interferon-γ production by tubulointerstitial human CD56bright natural killer cells contributes to renal fibrosis and chronic kidney disease progression