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2022 Journal Article CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tauPolanco, Juan Carlos, Akimov, Yevhen, Fernandes, Avinash, Briner, Adam, Hand, Gabriel Rhys, van Roijen, Marloes, Balistreri, Giuseppe and Götz, Jürgen (2022). CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau. Life Science Alliance, 6 (1) e202201689, 1-15. doi: 10.26508/lsa.202201689 |
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2021 Journal Article Exosomal and vesicle-free tau seeds - propagation and convergence in endolysosomal permeabilizationPolanco, Juan Carlos and Götz, Jürgen (2021). Exosomal and vesicle-free tau seeds - propagation and convergence in endolysosomal permeabilization. The FEBS Journal, 289 (22) febs.16055, 6891-6907. doi: 10.1111/febs.16055 |
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2021 Journal Article Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosolPolanco, Juan Carlos, Hand, Gabriel Rhys, Briner, Adam, Li, Chuanzhou and Götz, Jürgen (2021). Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol. Acta Neuropathologica, 141 (2), 235-256. doi: 10.1007/s00401-020-02254-3 |
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2020 Journal Article Fyn kinase controls tau aggregation in vivoBriner, Adam, Götz, Jürgen and Polanco, Juan Carlos (2020). Fyn kinase controls tau aggregation in vivo. Cell Reports, 32 (7) 108045, 108045. doi: 10.1016/j.celrep.2020.108045 |
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2018 Journal Article Are you TORCing tau me? Amyloid‐β blocks the conversation between lysosomes and mitochondriaPolanco, Juan Carlos and Götz, Jürgen (2018). Are you TORCing tau me? Amyloid‐β blocks the conversation between lysosomes and mitochondria. The EMBO Journal, 37 (22) e100839, e100839. doi: 10.15252/embj.2018100839 |
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2018 Journal Article Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neuronsPolanco, Juan Carlos, Li, Chuanzhou, Durisic, Nela, Sullivan, Robert and Götz, Jürgen (2018). Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neurons. Acta Neuropathologica Communications, 6 (1) 10, 1-14. doi: 10.1186/s40478-018-0514-4 |
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2017 Journal Article Amyloid-β and tau complexity - towards improved biomarkers and targeted therapiesPolanco, Juan Carlos, Li, Chuanzhou, Bodea, Liviu-Gabriel, Martinez-Marmol, Ramon, Meunier, Frederic A and Götz, Jürgen (2017). Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies. Nature reviews. Neurology, 14 (1), 22-40. doi: 10.1038/nrneurol.2017.162 |
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2016 Journal Article Extracellular vesicles isolated from the brains of rTg4510 mice seed tau protein aggregation in a threshold-dependent mannerPolanco, Juan Carlos, Scicluna, Benjamin James, Hill, Andrew Francis and Gotz, Jurgen (2016). Extracellular vesicles isolated from the brains of rTg4510 mice seed tau protein aggregation in a threshold-dependent manner. Journal of Biological Chemistry, 291 (24), 12445-12466. doi: 10.1074/jbc.M115.709485 |
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2016 Journal Article Extracellular vesicles containing P301L mutant tau accelerate pathological tau phosphorylation and oligomer formation but do not seed mature neurofibrillary tangles in ALZ17 miceBaker, Sian, Polanco, Juan Carlos and Gotz, Juergen (2016). Extracellular vesicles containing P301L mutant tau accelerate pathological tau phosphorylation and oligomer formation but do not seed mature neurofibrillary tangles in ALZ17 mice. Journal of Alzheimer's Disease, 54 (3), 1207-1217. doi: 10.3233/JAD-160371 |
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2015 Journal Article No full admission for tau to the exclusive prion club yetPolanco, Juan Carlos and Götz, Jürgen (2015). No full admission for tau to the exclusive prion club yet. EMBO Journal, 34 (24), 2990-2992. doi: 10.15252/embj.201593311 |
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2014 Journal Article Tau aggregation and its interplay with amyloid-βNisbet, Rebecca M., Polanco, Juan-Carlos, Ittner, Lars M. and Gotz, Jurgen (2014). Tau aggregation and its interplay with amyloid-β. Acta Neuropathologica, 129 (2), 207-220. doi: 10.1007/s00401-014-1371-2 |
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2013 Journal Article Enrichment and purging of human embryonic stem cells by detection of cell surface antigens using the monoclonal antibodies TG30 and GCTM-2Polanco, Juan Carlos, Wang, Bei, Zhou, Qi, Chy, Hun, O'Brien, Carmel and Laslett, Andrew L. (2013). Enrichment and purging of human embryonic stem cells by detection of cell surface antigens using the monoclonal antibodies TG30 and GCTM-2. Journal of Visualized Experiments (82) e50856. doi: 10.3791/50856 |
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2013 Journal Article Identification of Unsafe Human Induced Pluripotent Stem Cell Lines Using a Robust Surrogate Assay for PluripotencyPolanco, Juan Carlos, Ho, Mirabelle S. H., Wang, Bei, Zhou, Qi, Wolvetang, Ernst, Mason, Elizabeth, Wells, Christine A., Kolle, Gabriel, Grimmond, Sean M., Bertoncello, Ivan, O'Brien, Carmel and Laslett, Andrew L. (2013). Identification of Unsafe Human Induced Pluripotent Stem Cell Lines Using a Robust Surrogate Assay for Pluripotency. Stem Cells, 31 (8), 1498-1510. doi: 10.1002/stem.1425 |
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2010 Journal Article Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex developmentPolanco, J. C., Wilhelm, D, Davidson, T. L., Knight, D and Koopman, P (2010). Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development. Human Molecular Genetics, 19 (3) ddp520, 506-516. doi: 10.1093/hmg/ddp520 |
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2009 Journal Article Design of a molecular method for subspecies specific identification of Klebsiella pneumoniae by using the 16S ribosomal subunit geneArenas, Nelson Enrique, Polanco, Juan Carlos, Coronado, Sandra Milena, Durango, Clara Juliana and Gomez, Arley (2009). Design of a molecular method for subspecies specific identification of Klebsiella pneumoniae by using the 16S ribosomal subunit gene. Colombia Medica, 40 (3), 307-315. doi: 10.25100/cm.v40i3.659 |
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2009 Journal Article Design of a molecular method for subspecies specific identification of Klebsiella pneumoniae by using the 16S ribosomal subunit geneArenas, Nelson Enrique, Polanco, Juan Carlos, Coronado, Sandra Milena, Durango, Clara Juliana and Gomez, Arley (2009). Design of a molecular method for subspecies specific identification of Klebsiella pneumoniae by using the 16S ribosomal subunit gene. Colombia Medica, 40 (2), 194-201. doi: 10.25100/cm.v40i2.642 |
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2009 Journal Article Construcción de una filogenia molecular para las especies de los géneros Klebsiella y Raoultella basada en los genes ARNr 16S y ARN polimerasa subunidadArenas, Nelson Enrique, Gutiérrez, Andrés Julián, Salazar, Luz Mary, Polanco, Juan Carlos and Gómez, Arley (2009). Construcción de una filogenia molecular para las especies de los géneros Klebsiella y Raoultella basada en los genes ARNr 16S y ARN polimerasa subunidad. Revista Ciencias de la Salud, 7 (2), 22-29. |
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2009 Journal Article Functional analysis of the SRY–KRAB interaction in mouse sex determinationPolanco, Juan Carlos, Wilhelm, Dagmar, Mizusaki, Hirofumi, Jackson, Andrew, Browne, Catherine, Davidson, Tara, Harley, Vincent, Sinclair, Andrew and Koopman, Peter (2009). Functional analysis of the SRY–KRAB interaction in mouse sex determination. Biology of The Cell, 101 (1), 55-67. doi: 10.1042/BC20080061 |
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2007 Journal Article Sry and the hesitant beginnings of male developmentPolanco, Juan Carlos and Koopman, Peter (2007). Sry and the hesitant beginnings of male development. Developmental Biology, 302 (1), 13-24. doi: 10.1016/j.ydbio.2006.08.049 |
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2005 Conference Publication Possible role of KRAB-containing proteins in sex determinationPolanco, J. C., Jackson, A., Wilhelm, D. and Koopman, P. (2005). Possible role of KRAB-containing proteins in sex determination. AMSTERDAM: ELSEVIER SCIENCE BV. |
