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2014 Journal Article Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosisWang, Conan K., Gruber, Christian W., Cemazar, Masa, Siatskas, Christopher, Tagore, Prascilla, Payne, Natalie, Sun, Guizhi, Wang, Shunhe, Bernard, Claude C. and Craik, David J. (2014). Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis. ACS Chemical Biology, 9 (1), 156-163. doi: 10.1021/cb400548s |
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2013 Conference Publication Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosisWang, C. K., Gruber, C. W., Cernazar, M., Siatskas, C., Tagore, P., Sun, G., Wang, S., Bernard, C. and Craik, D. J. (2013). Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis. 23rd American Peptide Symposium, Waikoloa, Hawaii, 22-27 June 2013 . Hoboken, NJ, United States : John Wiley & Sons. |
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2012 Journal Article Cyclotides insert into lipid bilayers to form membrane pores and destabilize the membrane through hydrophobic and phosphoethanolamine-specific interactionsWang, Conan K., Wacklin, Hanna P. and Craik, David J. (2012). Cyclotides insert into lipid bilayers to form membrane pores and destabilize the membrane through hydrophobic and phosphoethanolamine-specific interactions. Journal of Biological Chemistry, 287 (52), 43884-43898. doi: 10.1074/jbc.M112.421198 |
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2012 Journal Article Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanismsWeeratunga, Saroja K., Osman, Asiah, Hu, Nien-Jen, Wang, Conan K., Mason, Lyndel, Svard, Staffan, Hope, Greg, Jones, Malcolm K. and Hofmann, Andreas (2012). Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms. Journal of Molecular Biology, 423 (2), 169-181. doi: 10.1016/j.jmb.2012.06.041 |
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2012 Journal Article Hookworm SCP/TAPS protein structure - A key to understanding host-parasite interactions and developing new interventionsOsman, Asiah, Wang, Conan K., Winter, Anja, Loukas, Alex, Tribolet, Leon, Gasser, Robin B. and Hofmann, Andreas (2012). Hookworm SCP/TAPS protein structure - A key to understanding host-parasite interactions and developing new interventions. Biotechnology Advances, 30 (3), 652-657. doi: 10.1016/j.biotechadv.2011.11.002 |
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2012 Journal Article Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migrationXavier, Charles-Peter, Rastetter, Raphael H., Blomacher, Margit, Stumpf, Maria, Himmel, Mirko, Morgan, Reginald O., Fernandez, Maria-Pilar, Wang, Conan, Osman, Asiah, Miyata, Yoshihiko, Gjerset, Ruth A., Eichinger, Ludwig, Hofmann, Andreas, Linder, Stefan, Noegel, Angelika A. and Clemen, Christoph S. (2012). Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration. Scientific Reports, 2 (1) 241. doi: 10.1038/srep00241 |
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2012 Book Chapter Cyclotide isolation and characterizationCraik, David J., Henriques, Sonia Troeira, Mylne, Joshua S. and Wang, Conan K. (2012). Cyclotide isolation and characterization. Natural product biosynthesis by microorganisms and plants, part B. (pp. 37-62) edited by David A. Hopwood. Burlington, USA: Elsevier. doi: 10.1016/B978-0-12-394291-3.00024-1 |
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2012 Journal Article SBAL: A practical tool to generate and edit structure-based amino acid sequence alignmentsWang, Conan K., Broder, Ursula, Weeratunga, Saroja K., Gasser, Robin B., Loukas, Alex and Hofmann, Andreas (2012). SBAL: A practical tool to generate and edit structure-based amino acid sequence alignments. Bioinformatics, 28 (7) bts035, 1026-1027. doi: 10.1093/bioinformatics/bts035 |
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2011 Journal Article DMAN: a java tool for analysis of multi-well differential scanning fluorimetry experimentsWang, Conan K., Weeratunga, Saroja K., Pacheco, Chris M. and Hofmann, Andreas (2011). DMAN: a java tool for analysis of multi-well differential scanning fluorimetry experiments. Bioinformatics, 28 (3) btr664, 439-440. doi: 10.1093/bioinformatics/btr664 |
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2011 Journal Article Promiscuity of carbonic anhydrase II: Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitorsLopez, Marie, Vu. Hoan, Wang, Conan K., Wolf, Maarten G., Groenhof, Gerrit, Innocentis, Alessio, Supuran, Claudiu T. and Poulsen, Sally-Ann (2011). Promiscuity of carbonic anhydrase II: Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. Journal of The American Chemical Society, 133 (45), 18452-18462. doi: 10.1021/ja207855c |
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2011 Journal Article Divalent cations and Redox conditions regulate the molecular structure and function of visinin-like protein-1Wang, Conan K., Simon, Anne, Jessen, Christian M., Oliveira, Cristiano L. P., Mack, Lynsey, Braunewell, Karl-Heinz, Ames, James B., Pedersen, Jan Skov and Hofmann, Andreas (2011). Divalent cations and Redox conditions regulate the molecular structure and function of visinin-like protein-1. PLoS One, 6 (11) ARTN e26793, e26793.1-e26793.10. doi: 10.1371/journal.pone.0026793 |
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2011 Journal Article Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookwormWillis, Charlene, Wang, Conan K., Osman, Asiah, Simon, Anne, Pickering, Darren, Mulvenna, Jason, Riboldi-Tunicliffe, Alan, Jones, Malcolm K., Loukas, Alex and Hofmann, Andreas (2011). Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm. PLoS One, 6 (10) e25369, e25369.1-e25369.10. doi: 10.1371/journal.pone.0025369 |
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2011 Journal Article Atypical (RIO) protein kinases from Haemonchus contortus-promise as new targets for nematocidal drugsCampbell, Bronwyn E., Boag, Peter R., Hofmann, Andreas, Cantacessi, Cinzia, Wang, Conan K., Taylor, Paul, Hu, Min, Sindhu, Zia-ud-Din, Loukas, Alex, Sternberg, Paul W. and Gasser, Robin B. (2011). Atypical (RIO) protein kinases from Haemonchus contortus-promise as new targets for nematocidal drugs. Biotechnology Advances, 29 (3), 338-350. doi: 10.1016/j.biotechadv.2011.01.006 |
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2011 Journal Article The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutantWang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153 |
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2010 Journal Article Isolation and characterization of Bioactive Cyclotides from Viola labriloricaTang, Jun, Wang, Conan K., Pan, Xulin, Yan, He, Zeng, Guangzhi, Xu, Wenyan, He, Wenjun, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2010). Isolation and characterization of Bioactive Cyclotides from Viola labrilorica. Helvetica Chimica Acta, 93 (11), 2287-2295. doi: 10.1002/hlca.201000115 |
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2010 Journal Article Merging structural biology with chemical biology: Structural Chemistry at EskitisHofmann, Andreas, Wang, Con, Osman, Asiah and Camp, David (2010). Merging structural biology with chemical biology: Structural Chemistry at Eskitis. Structural Chemistry, 21 (5), 1117-1129. doi: 10.1007/s11224-010-9654-2 |
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2010 Journal Article Isolation and characterization of cytotoxic cyclotides from Viola tricolorTang, Jun, Wang, Conan K., Pan, Xulin, Yan, He, Zeng, Guangzhi, Xu, Wenyan, He, Wenjun, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2010). Isolation and characterization of cytotoxic cyclotides from Viola tricolor. Peptides, 31 (8), 1434-1440. doi: 10.1016/j.peptides.2010.05.004 |
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2010 Journal Article Extensions of PDZ domains as important structural and functional elementsWang, Conan K., Pan, Lifeng, Chen, Jia and Zhang, Mingjie (2010). Extensions of PDZ domains as important structural and functional elements. Protein & Cell, 1 (8), 737-751. doi: 10.1007/s13238-010-0099-6 |
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2010 Journal Article Cyclotides are a component of the innate defense of Oldenlandia affinisMylne, Joshua S, Wang, Conan K, van der Weerden, Nicole L and Craik, David J (2010). Cyclotides are a component of the innate defense of Oldenlandia affinis. Biopolymers, 94 (5), 635-646. doi: 10.1002/bip.21419 |
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2010 Conference Publication Cyclotides are a component of the innate defense of Oldenlandia affinisMylne, Joshua S., Wang, Conan K., van der Weerden, Nicole L. and Craik, David J. (2010). Cyclotides are a component of the innate defense of Oldenlandia affinis. 1st International Conference on Circular Proteins, Heron Island, Qld, Australia, 18-21 October, 2009. Hoboken, NJ, United States: Wiley. doi: 10.1002/bip.21419 |
