|
2014 Journal Article Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implicationsSunagar, Kartik, Undheim, Eivind A. B., Scheib, Holger, Gren, Eric C. K., Cochran, Chip, Person, Carl E., Koludarov, Ivan, Kelln, Wayne, Hayes, William K., King, Glenn F., Antunes, Agosthino and Fry, Bryan Grieg (2014). Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications. Journal of Proteomics, 99, 68-83. doi: 10.1016/j.jprot.2014.01.013 |
|
2014 Journal Article Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spidersPineda, Sandy S., Sollod, Brianna L., Wilson, David, Darling, Aaron, Sunagar, Kartik, Undheim, Eivind A. B., Kely, Laurence, Antunes, Agostinho, Fry, Bryan G. and King, Glenn F (2014). Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders. BMC Genomics, 15 (1) 177, 177.1-177.16. doi: 10.1186/1471-2164-15-177 |
|
2014 Journal Article A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domainGui, Junhong, Liu, Boyi, Cao, Guan, Lipchik, Andrew M., Perez, Minervo, Dekan, Zoltan, Mobli, Mehdi, Daly, Norelle L., Alewood, Paul F., Parker, Laurie L., King, Glenn F., Zhou, Yufeng, Jordt, Sven-Eric and Nitabach, Michael N. (2014). A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain. Current Biology, 24 (5), 473-483. doi: 10.1016/j.cub.2014.01.013 |
|
2014 Journal Article Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angewandte Chemie, 126 (4), 1035-1038. doi: 10.1002/ange.201308898 |
|
2014 Journal Article Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2. Angewandte Chemie International Edition, 53 (4), 1017-1020. doi: 10.1002/anie.201308898 |
|
2014 Journal Article The future of venoms-based drug discovery: an interview with Glenn KingKing, Glenn F. (2014). The future of venoms-based drug discovery: an interview with Glenn King. Future Medicinal Chemistry, 6 (15), 1613-1615. doi: 10.4155/FMC.14.102 |
|
2014 Journal Article Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal painDantas De Araujo, Aline, Mobli, Mehdi, Castro, Joel, Harrington, Andrea M., Vetter, Irina, Dekan, Zoltan, Muttenthale, Markus, Wan, JingJing, Lewis, Richard J., King, Glenn F., Brierley, Stuart M. and Alewood, Paul F. (2014). Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications, 5 (1) 3165, 3165.1-3165.12. doi: 10.1038/ncomms4165 |
|
2014 Journal Article Methods for deployment of spider venom peptides as bioinsecticidesHerzig, Volker, Bende, Niraj S., Alam, Md. Shohidul, Tedford, H. William, Kennedy, Robert M. and King, Glenn F. (2014). Methods for deployment of spider venom peptides as bioinsecticides. Advances in Insect Physiology, 47, 389-411. doi: 10.1016/B978-0-12-800197-4.00008-7 |
|
2014 Conference Publication Discovery of voltage-gated sodium channel inhibitors from tarantula venomsCardoso, F. C., Dekan, Z., Anangi, R., Rosengren, K. J., Erickson, A., Vetter, I., Herzig, V., Alewood, P., King, G. F. and Lewis, R. J. (2014). Discovery of voltage-gated sodium channel inhibitors from tarantula venoms. Venom to Drugs Conference 2014, Kingscliffe, NSW, Australia, 19-23 October 2014. |
|
2014 Journal Article Spider venomics: implications for drug discoveryPineda, Sandy S., Undheim, Eivind A. B., Rupasinghe, Darshani B., Ikonomopoulou, Maria P. and King, Glenn F. (2014). Spider venomics: implications for drug discovery. Future Medicinal Chemistry, 6 (15), 1699-1714. doi: 10.4155/FMC.14.103 |
|
2014 Book Chapter Peptide therapeutics from venomous creaturesLavergne, Vincent, King, Glenn F., Lewis, Richard J. and Alewood, Paul F. (2014). Peptide therapeutics from venomous creatures. Pain therapeutics: current and future treatment paradigms. (pp. 217-246) edited by Charlotte Allerton. London, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849737715-00217 |
|
2014 Journal Article Toxin delivery by the coat protein of an aphid-vectored plant virus provides plant resistance to aphidsBonning, Bryony C., Pal, Narinder, Liu, Sijun, Wang, Zhaohui, Sivakumar, S., Dixon, Philip M., King, Glenn F. and Miller, W. Allen (2014). Toxin delivery by the coat protein of an aphid-vectored plant virus provides plant resistance to aphids. Nature Biotechnology, 32 (1), 102-105. doi: 10.1038/nbt.2753 |
|
2014 Journal Article Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping PharmacophoresJensen, Jonas E., Cristofori-Armstrong, Ben, Anangi, Raveendra, Rosengren, K. Johan, Lau, Carus H. Y., Mobli, Mehdi, Brust, Andreas, Alewood, Paul F., King, Glenn F. and Rash, Lachlan D. (2014). Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores. Journal of Medicinal Chemistry, 57 (21), 9195-9203. doi: 10.1021/jm501400p |
|
2014 Conference Publication Optimizing the potency and selectivity of a spider-venom peptide that inhibitis the analgesic target Nav1.7.Erickson, A., Cardoso, F. C., Lewis, R. J. and King, G. F. (2014). Optimizing the potency and selectivity of a spider-venom peptide that inhibitis the analgesic target Nav1.7.. Venom to Drugs Conference 2014, Kingscliffe, NSW, Australia, 19-23 October 2014. |
|
2013 Journal Article Venoms to drugs: translating venom peptides into therapeuticsKing, Glenn (2013). Venoms to drugs: translating venom peptides into therapeutics. Australian Biochemist, 44 (3). |
|
2013 Journal Article Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?Dantas De Araujo, Aline, Herzig, Volker, Windley, Monique J., Dziemborowicz, Slawomir, Mobli, Mehdi, Nicholson, Graham M., Alewood, Paul F. and King, Glenn F. (2013). Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?. Antioxidants and Redox Signaling, 19 (16), 1976-1980. doi: 10.1089/ars.2013.5365 |
|
2013 Journal Article Molecular evolution of vertebrate neurotrophins: co-option of the highly conserved nerve growth factor gene into the advanced snake venom arsenalfSunagar, Kartik, Fry, Bryan Grieg, Jackson, Timothy N. W., Casewell, Nicholas R., Undheim, Eivind A. B., Vidal, Nicolas, Ali, Syed A., King, Glenn F., Vasudevan, Karthikeyan, Vasconcelos, Vitor and Antunes, Agostinho (2013). Molecular evolution of vertebrate neurotrophins: co-option of the highly conserved nerve growth factor gene into the advanced snake venom arsenalf. PLoS One, 8 (11) e81827, e81827.1-e81827.19. doi: 10.1371/journal.pone.0081827 |
|
2013 Journal Article Discovery of a selective Na(V)1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain modelsYang, Shilong, Xiao, Yao, Kang, Di, Liu, Jie, Li, Yuan, Undheim, Eivind A. B., Klint, Julie K., Rong, Mingqiang, Lai, Ren and King, Glenn F. (2013). Discovery of a selective Na(V)1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models. Proceedings of the National Academy of Sciences of the United States of America, 110 (43), 17534-17539. doi: 10.1073/pnas.1306285110 |
|
2013 Journal Article Isolation of an orally active insecticidal toxin from the venom of an Australian tarantulaHardy, Margaret C., Daly, Norelle L., Mobli, Mehdi, Morales, Rodrigo A. V. and King, Glenn F. (2013). Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula. PLoS ONE, 8 (9), e73136.1-e73136.12. doi: 10.1371/journal.pone.0073136 |
|
2013 Journal Article Functional characterization on invertebrate and vertebrate tissues of tachykinin peptides from octopus venomsRuder, Tim, Ali, Syed Abid, Ormerod, Kiel, Brust, Andreas, Roymanchadi, Mary-Louise, Ventura, Sabatino, Undheim, Eivind A. B., Jackson, Timothy N. W., Mercier, A. Joffre, King, Glenn F., Alewood, Paul F. and Fry, Bryan G. (2013). Functional characterization on invertebrate and vertebrate tissues of tachykinin peptides from octopus venoms. Peptides, 47, 71-76. doi: 10.1016/j.peptides.2013.07.002 |
