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2017

Conference Publication

Nav modulators in spider venoms and applications in the development of novel therapies for neurological disorders

Cardoso, Fernanda C., Bellingham, Mark C., King, Glenn F. and Lewis, Richard J. (2017). Nav modulators in spider venoms and applications in the development of novel therapies for neurological disorders. Venom to Drugs Conference 2017, Noosa Heads, QLD Australia, 9-14 October 2017.

Nav modulators in spider venoms and applications in the development of novel therapies for neurological disorders

2017

Journal Article

The use of imaging mass spectrometry to study peptide toxin distribution in Australian sea anemones

Mitchell, Michela L., Hamilton, Brett R., Madio, Bruno, Morales, Rodrigo A. V., Tonkin-Hill, Gerry Q., Papenfuss, Anthony T., Purcell, Anthony W., King, Glenn F., Undheim, Eivind A. B. and Norton, Raymond S. (2017). The use of imaging mass spectrometry to study peptide toxin distribution in Australian sea anemones. Australian Journal of Chemistry, 70 (11), 1235-1237. doi: 10.1071/CH17228

The use of imaging mass spectrometry to study peptide toxin distribution in Australian sea anemones

2017

Journal Article

Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discovery

Robinson, Samuel D., Undheim, Eivind A. B., Ueberheide, Beatrix and King, Glenn F. (2017). Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discovery. Expert Review of Proteomics, 14 (10), 931-939. doi: 10.1080/14789450.2017.1377613

Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discovery

2017

Conference Publication

Discovery of novel CaV and NaV modulators in spider venoms and applications in the development of drugs to treat chronic pain.

Cardoso, Fernanda C., King, Glenn F. and Lewis, Richard J. (2017). Discovery of novel CaV and NaV modulators in spider venoms and applications in the development of drugs to treat chronic pain.. 19th World Congress of the International Society on Toxinology, Haikou City, Hainan Province, China, 24-31 October 2017.

Discovery of novel CaV and NaV modulators in spider venoms and applications in the development of drugs to treat chronic pain.

2017

Conference Publication

Novel Human Eag Channel Antagonists from Spider Venoms

Ma, Linlin, Chin, Yanni K., Dekan, Zoltan, Ikonomopoulou, Maria, Herzig, Volker, Chow, Chun Yuen, Alewood, Paul and King, Glenn F. (2017). Novel Human Eag Channel Antagonists from Spider Venoms. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, United States, 15-19 February 2014. St. Louis, MO 63146 United States: Cell Press. doi: 10.1016/j.bpj.2016.11.1800

Novel Human Eag Channel Antagonists from Spider Venoms

2016

Journal Article

Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix

Ikonomopoulou, Maria P., Smith, Jennifer J., Herzig, Volker, Pineda, Sandy S., Dziemborowicz, Sławomir, Er, Sing-Yan, Durek, Thomas, Gilchrist, John, Alewood, Paul F., Nicholson, Graham M., Bosmans, Frank and King, Glenn F. (2016). Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix. Toxicon, 123, 62-70. doi: 10.1016/j.toxicon.2016.10.013

Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix

2016

Journal Article

Centipede venoms as a source of drug leads

Undheim, Eivind A. B., Jenner, Ronald A. and King, Glenn F. (2016). Centipede venoms as a source of drug leads. Expert Opinion on Drug Discovery, 11 (12), 1139-1149. doi: 10.1080/17460441.2016.1235155

Centipede venoms as a source of drug leads

2016

Journal Article

Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR data

Mohanty, Biswaranjan, Williams, Martin L., Doak, Bradley C., Vazirani, Mansha, Ilyichova, Olga, Wang, Geqing, Bermel, Wolfgang, Simpson, Jamie S., Chalmers, David K., King, Glenn F., Mobli, Mehdi and Scanlon, Martin J. (2016). Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR data. Journal of Biomolecular NMR, 66 (3), 195-208. doi: 10.1007/s10858-016-0067-4

Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR data

2016

Journal Article

Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels

Lau, Carus H.Y., King, Glenn F and Mobli, Mehdi (2016). Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels. Scientific Reports, 6 (1) 34333, 34333. doi: 10.1038/srep34333

Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels

2016

Journal Article

Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7

Troeira Henriques, Sonia, Deplazes, Evelyne, Lawrence, Nicole, Cheneval, Olivier, Chaousis, Stephanie, Inserra, Marco, Thongyoo, Panumart, King, Glenn F., Mark, Alan E., Vetter, Irina, Craik, David J. and Schroeder, Christina Ingrid (2016). Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7. The Journal of Biological Chemistry, 291 (33), 17049-17065. doi: 10.1074/jbc.M116.729095

Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7

2016

Journal Article

Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatus

Touchard, Axel, Brust, Andreas, Cardoso, Fernanda C., Chin, K.-Y., Herzig, Volker, Jin, Ai-Hua, Dejean, Alain, Alewood, Paul F., King, Glenn F., Orivel, Jérôme and Escoubas, Pierre (2016). Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatus. Biochimica et Biophysica Acta, 1860 (11 Part A), 2553-2562. doi: 10.1016/j.bbagen.2016.07.027

Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatus

2016

Journal Article

Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury

Koehn, Liam M, Noor, Natassya M, Dong, Qing, Er, Sing-Yan, Rash, Lachlan D, King, Glenn F, Dziegielewska, Katarzyna M, Saunders, Norman R and Habgood, Mark D (2016). Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury. F1000Research, 5 1822, 1822. doi: 10.12688/f1000research.9094.2

Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury

2016

Journal Article

Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury [version 1; referees: 1 approved, 1 approved with reservations]

Koehn, Liam M., Dong, Qing, Er, Sing-Yan, Rash, Lachlan D., King, Glenn F., Dziegielewska, Katarzyna M., Saunders, Norman R. and Habgood, Mark D. (2016). Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury [version 1; referees: 1 approved, 1 approved with reservations]. F1000Research, 5 1822, 1822. doi: 10.12688/F1000RESEARCH.9094.1

Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury [version 1; referees: 1 approved, 1 approved with reservations]

2016

Journal Article

Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami

Herzig, Volker, Ikonomopoulou, Maria, Smith, Jennifer J., Dziemborowicz, Slawomir, Gilchrist, John, Kuhn-Nentwig, Lucia, Rezende, Fernanda Oliveira, Moreira, Luciano Andrade, Nicholson, Graham M., Bosmans, Frank and King, Glenn F. (2016). Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami. Scientific Reports, 6 (1) 29538, 29538. doi: 10.1038/srep29538

Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami

2016

Journal Article

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain

Osteen, Jeremiah D., Herzig, Volker, Gilchrist, John, Emrick, Joshua J., Zhang, Chuchu, Wang, Xidao, Castro, Joel, Garcia-Caraballo, Sonia, Grundy, Luke, Rychkov, Grigori Y., Weyer, Andy D., Dekan, Zoltan, Undheim, Eivind A. B., Alewood, Paul, Stucky, Cheryl L., Brierley, Stuart M., Basbaum, Allan I., Bosmans, Frank, King, Glenn F. and Julius, David (2016). Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature, 543 (7608), 494-499. doi: 10.1038/nature17976

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain

2016

Journal Article

Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides

Undheim, Eivind A., Mobli, Mehdi and King, Glenn F. (2016). Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides. Bioessays, 38 (6), 539-548. doi: 10.1002/bies.201500165

Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides

2016

Journal Article

Characterization of Three Venom Peptides from the Spitting Spider Scytodes thoracica

Ariki, Nathanial K., Muñoz, Lisa E., Armitage, Elizabeth L., Goodstein, Francesca R., George, Kathryn G, Smith, Vanessa L., Vetter, Irina, Herzig, Volker, King, Glenn F. and Loening, Nikolaus M. (2016). Characterization of Three Venom Peptides from the Spitting Spider Scytodes thoracica. PLoS One, 11 (5) e0156291, e0156291. doi: 10.1371/journal.pone.0156291

Characterization of Three Venom Peptides from the Spitting Spider Scytodes thoracica

2016

Conference Publication

Combining Mass Spectrometry Cross‐Linking, Molecular Docking and NMR Titration to Dissect ZapA‐FtsZ Protein Interaction

Nogueira, Maria Luiza Caldas, Sforça, Mauricio Luis, Leme, Adriana Franco Paes, Pauletti, Bianca Alves, de Oliveira, Paulo Sergio Lopes, Honorato, Rodrigo Vargas, King, Glenn F., Filho, Frederico José Gueiros and de Mattos Zeri, Ana Carolina (2016). Combining Mass Spectrometry Cross‐Linking, Molecular Docking and NMR Titration to Dissect ZapA‐FtsZ Protein Interaction. Experimental Biology 2016 Meeting, San Diego, CA United States, 1-5 April 2016. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.30.1_supplement.lb60

Combining Mass Spectrometry Cross‐Linking, Molecular Docking and NMR Titration to Dissect ZapA‐FtsZ Protein Interaction

2016

Conference Publication

Combining Mass Spectrometry Cross-Linking, Molecular Docking and NMR Titration to Dissect ZapA-FtsZ Protein Interaction

Caldas Nogueira, Maria Luiza, Sforca, Mauricio Luis, Paes Leme, Adriana Franco, Pauletti, Bianca Alves, Lopes de Oliveira, Paulo Sergio, Honorato, Rodrigo Vargas, King, Glenn F., Gueiros Filho, Frederico Jose and de Mattos Zeri, Ana Carolina (2016). Combining Mass Spectrometry Cross-Linking, Molecular Docking and NMR Titration to Dissect ZapA-FtsZ Protein Interaction. Experimental Biology Meeting, San Diego Ca, Apr 02-06, 2016. BETHESDA: FEDERATION AMER SOC EXP BIOL.

Combining Mass Spectrometry Cross-Linking, Molecular Docking and NMR Titration to Dissect ZapA-FtsZ Protein Interaction

2016

Journal Article

Venoms of heteropteran insects: a treasure trove of diverse pharmacological toolkits

Walker, Andrew A., Weirauch, Christiane, Fry, Bryan G. and King, Glenn F. (2016). Venoms of heteropteran insects: a treasure trove of diverse pharmacological toolkits. Toxins, 8 (2) 43, 43. doi: 10.3390/toxins8020043

Venoms of heteropteran insects: a treasure trove of diverse pharmacological toolkits