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2017 Journal Article Venom profiling of a population of the theraphosid spider Phlogius crassipes reveals continuous ontogenetic changes from juveniles through adulthoodSantana, Renan C., Perez, David, Dobson, James, Panagides, Nadya, Raven, Robert J., Nouwens, Amanda, Jones, Alun, King, Glenn F. and Fry, Bryan G. (2017). Venom profiling of a population of the theraphosid spider Phlogius crassipes reveals continuous ontogenetic changes from juveniles through adulthood. Toxins, 9 (4) 116, 116. doi: 10.3390/toxins9040116 |
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2017 Journal Article The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variantRahnama, Sassan, Deuis, Jennifer R., Cardoso, Fernanda C., Ramanujam, Venkatraman, Lewis, Richard J., Rash, Lachlan D., King, Glenn F., Vetter, Irina and Mobli, Mehdi (2017). The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant. PLoS One, 12 (3) e0173551, e0173551. doi: 10.1371/journal.pone.0173551 |
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2017 Journal Article Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1aChassagnon, Irene R., McCarthy, Claudia A., Chin, Yanni K.-Y., Pineda, Sandy S., Keramidas, Angelo, Mobli, Mehdi, Pham, Vi, De Silva, T. Michael, Lynch, Joseph W., Widdop, Robert E., Rash, Lachlan D. and King, Glenn F. (2017). Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a. Proceedings from the National Academy of Sciences of the United States of America, 114 (14), 3750-3755. doi: 10.1073/pnas.1614728114 |
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2017 Journal Article Insecticidal activity of a recombinant knottin peptide from Loxosceles intermedia venom and recognition of these peptides as a conserved family in the genusMatsubara, F. H., Meissner, G. O., Herzig, V., Justa, H. C., Dias, B. C. L., Trevisan-Silva, D., Gremski, L. H., Gremski, W., Senff-Ribeiro, A., Chaim, O. M., King, G. F. and Veiga, S. S. (2017). Insecticidal activity of a recombinant knottin peptide from Loxosceles intermedia venom and recognition of these peptides as a conserved family in the genus. Insect Molecular Biology, 26 (1), 25-34. doi: 10.1111/imb.12268 |
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2017 Journal Article Pharmacological characterisation of the highly Nav1.7 selective spider venom peptide Pn3aDeuis, Jennifer R., Dekan, Zoltan, Wingerd, Joshua S., Smith, Jennifer J., Munasinghe, Nehan R., Bhola, Rebecca F., Imlach, Wendy L., Herzig, Volker, Armstrong, David A., Rosengren, K. Johan, Bosmans, Frank, Waxman, Stephen G., Dib-Hajj, Sulayman D., Escoubas, Pierre, Minett, Michael S., Christie, Macdonald J., King, Glenn F., Alewood, Paul F., Lewis, Richard J., Wood, John N. and Vetter, Irina (2017). Pharmacological characterisation of the highly Nav1.7 selective spider venom peptide Pn3a. Scientific Reports, 7 (1) 40883, 40883. doi: 10.1038/srep40883 |
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2017 Journal Article The use of imaging mass spectrometry to study peptide toxin distribution in Australian sea anemonesMitchell, Michela L., Hamilton, Brett R., Madio, Bruno, Morales, Rodrigo A. V., Tonkin-Hill, Gerry Q., Papenfuss, Anthony T., Purcell, Anthony W., King, Glenn F., Undheim, Eivind A. B. and Norton, Raymond S. (2017). The use of imaging mass spectrometry to study peptide toxin distribution in Australian sea anemones. Australian Journal of Chemistry, 70 (11), 1235-1237. doi: 10.1071/CH17228 |
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2017 Journal Article Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discoveryRobinson, Samuel D., Undheim, Eivind A. B., Ueberheide, Beatrix and King, Glenn F. (2017). Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discovery. Expert Review of Proteomics, 14 (10), 931-939. doi: 10.1080/14789450.2017.1377613 |
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2017 Conference Publication Discovery of novel CaV and NaV modulators in spider venoms and applications in the development of drugs to treat chronic pain.Cardoso, Fernanda C., King, Glenn F. and Lewis, Richard J. (2017). Discovery of novel CaV and NaV modulators in spider venoms and applications in the development of drugs to treat chronic pain.. 19th World Congress of the International Society on Toxinology, Haikou City, Hainan Province, China, 24-31 October 2017. |
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2017 Conference Publication Novel Human Eag Channel Antagonists from Spider VenomsMa, Linlin, Chin, Yanni K., Dekan, Zoltan, Ikonomopoulou, Maria, Herzig, Volker, Chow, Chun Yuen, Alewood, Paul and King, Glenn F. (2017). Novel Human Eag Channel Antagonists from Spider Venoms. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, United States, 15-19 February 2014. St. Louis, MO 63146 United States: Cell Press. doi: 10.1016/j.bpj.2016.11.1800 |
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2017 Book Chapter A Strategy for production of correctly folded disulfide-rich peptides in the periplasm of E. coliSaez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra and King, Glenn F. (2017). A Strategy for production of correctly folded disulfide-rich peptides in the periplasm of E. coli. In Heterologous Gene Expression in E. coli Methods and Protocols (pp. 155-180) New York, NY United States: Humana Press. doi:10.1007/978-1-4939-6887-9_10 |
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2017 Conference Publication Nav modulators in spider venoms and applications in the development of novel therapies for neurological disordersCardoso, Fernanda C., Bellingham, Mark C., King, Glenn F. and Lewis, Richard J. (2017). Nav modulators in spider venoms and applications in the development of novel therapies for neurological disorders. Venom to Drugs Conference 2017, Noosa Heads, QLD Australia, 9-14 October 2017. |
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2016 Journal Article Centipede venoms as a source of drug leadsUndheim, Eivind A. B., Jenner, Ronald A. and King, Glenn F. (2016). Centipede venoms as a source of drug leads. Expert Opinion on Drug Discovery, 11 (12), 1139-1149. doi: 10.1080/17460441.2016.1235155 |
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2016 Journal Article Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropixIkonomopoulou, Maria P., Smith, Jennifer J., Herzig, Volker, Pineda, Sandy S., Dziemborowicz, Sławomir, Er, Sing-Yan, Durek, Thomas, Gilchrist, John, Alewood, Paul F., Nicholson, Graham M., Bosmans, Frank and King, Glenn F. (2016). Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix. Toxicon, 123, 62-70. doi: 10.1016/j.toxicon.2016.10.013 |
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2016 Journal Article Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR dataMohanty, Biswaranjan, Williams, Martin L., Doak, Bradley C., Vazirani, Mansha, Ilyichova, Olga, Wang, Geqing, Bermel, Wolfgang, Simpson, Jamie S., Chalmers, David K., King, Glenn F., Mobli, Mehdi and Scanlon, Martin J. (2016). Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR data. Journal of Biomolecular NMR, 66 (3), 195-208. doi: 10.1007/s10858-016-0067-4 |
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2016 Journal Article Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channelsLau, Carus H.Y., King, Glenn F and Mobli, Mehdi (2016). Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels. Scientific Reports, 6 (1) 34333, 34333. doi: 10.1038/srep34333 |
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2016 Journal Article Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7Troeira Henriques, Sonia, Deplazes, Evelyne, Lawrence, Nicole, Cheneval, Olivier, Chaousis, Stephanie, Inserra, Marco, Thongyoo, Panumart, King, Glenn F., Mark, Alan E., Vetter, Irina, Craik, David J. and Schroeder, Christina Ingrid (2016). Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7. The Journal of Biological Chemistry, 291 (33), 17049-17065. doi: 10.1074/jbc.M116.729095 |
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2016 Journal Article Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatusTouchard, Axel, Brust, Andreas, Cardoso, Fernanda C., Chin, K.-Y., Herzig, Volker, Jin, Ai-Hua, Dejean, Alain, Alewood, Paul F., King, Glenn F., Orivel, Jérôme and Escoubas, Pierre (2016). Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatus. Biochimica et Biophysica Acta, 1860 (11 Part A), 2553-2562. doi: 10.1016/j.bbagen.2016.07.027 |
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2016 Journal Article Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injuryKoehn, Liam M, Noor, Natassya M, Dong, Qing, Er, Sing-Yan, Rash, Lachlan D, King, Glenn F, Dziegielewska, Katarzyna M, Saunders, Norman R and Habgood, Mark D (2016). Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury. F1000Research, 5 1822, 1822. doi: 10.12688/f1000research.9094.2 |
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2016 Journal Article Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury [version 1; referees: 1 approved, 1 approved with reservations]Koehn, Liam M., Dong, Qing, Er, Sing-Yan, Rash, Lachlan D., King, Glenn F., Dziegielewska, Katarzyna M., Saunders, Norman R. and Habgood, Mark D. (2016). Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury [version 1; referees: 1 approved, 1 approved with reservations]. F1000Research, 5 1822, 1822. doi: 10.12688/F1000RESEARCH.9094.1 |
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2016 Journal Article Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendamiHerzig, Volker, Ikonomopoulou, Maria, Smith, Jennifer J., Dziemborowicz, Slawomir, Gilchrist, John, Kuhn-Nentwig, Lucia, Rezende, Fernanda Oliveira, Moreira, Luciano Andrade, Nicholson, Graham M., Bosmans, Frank and King, Glenn F. (2016). Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami. Scientific Reports, 6 (1) 29538, 29538. doi: 10.1038/srep29538 |
