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2016 Journal Article Membrane-binding properties of gating modifier and pore-blocking toxins: membrane interaction is not a prerequisite for modification of channel gatingDeplazes, Evelyne, Troeira Henriques, Sonia, Smith, Jennifer J., King, Glenn F., Craik, David J., Mark, Alan E. and Schroeder, Christina I. (2016). Membrane-binding properties of gating modifier and pore-blocking toxins: membrane interaction is not a prerequisite for modification of channel gating. Biochimica et Biophysica Acta - Biomembranes, 1858 (4), 872-882. doi: 10.1016/j.bbamem.2016.02.002 |
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2016 Conference Publication Membrane-binding properties of gating-modifier and pore blocking toxins: membrane interaction is not a prerequisite for modification of channel gatingDeplazes, Evelyne, Henriques, Sonia Troeira, King, Glenn F., Craik, David J., Mark, Alan E. and Schroeder, Christina I. (2016). Membrane-binding properties of gating-modifier and pore blocking toxins: membrane interaction is not a prerequisite for modification of channel gating. 60th Annual Meeting of the Biophysical-Society, Los Angeles, United States, February 27- March 2 2016. St Louis, United States: Cell Press. doi: 10.1016/j.bpj.2015.11.220 |
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2016 Conference Publication Using Spider Venom Peptides as Molecular Tools for Understanding Voltage-Gated Sodium Channel FunctionHerzig, V., Osteen, J. D., Bosmans, F., Julius, D. and King, G. F. (2016). Using Spider Venom Peptides as Molecular Tools for Understanding Voltage-Gated Sodium Channel Function. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. HOBOKEN: Wiley. |
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2016 Conference Publication Exploring the immunosuppressive potential of venom-derived moleculesRyan, R., Ikonomopoulou, M., Haigh, O., Lutzky, V, Martinez, Jimenez R., Ratnatunga, C., Wong, Y., Rojas, Leal, I, Lopez, A., Fry, B., Herzig, V, King, G. and Miles, J. (2016). Exploring the immunosuppressive potential of venom-derived molecules. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200 |
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2016 Journal Article Combination of Ambiguous and Unambiguous Data in the Restraint-driven Docking of Flexible Peptides with HADDOCK: The Binding of the Spider Toxin PcTx1 to the Acid Sensing Ion Channel (ASIC) 1aDeplazes, Evelyne, Davies, Josephine, Bonvin, Alexandre M. J. J., King, Glenn F. and Mark, Alan E. (2016). Combination of Ambiguous and Unambiguous Data in the Restraint-driven Docking of Flexible Peptides with HADDOCK: The Binding of the Spider Toxin PcTx1 to the Acid Sensing Ion Channel (ASIC) 1a. Journal of Chemical Information and Modeling, 56 (1), 127-138. doi: 10.1021/acs.jcim.5b00529 |
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2016 Conference Publication Investigating venom-derived molecules that augment human immune functionJimenez-Martinez, R., Ikonomopoulou, M., Haigh, O., Lutzky, V, Leal-Rojas, I, Ryan, R., Ratnatunga, C., Wong, Y., Lopez, A., Fry, B., Herzig, V, King, G. and Miles, J. J. (2016). Investigating venom-derived molecules that augment human immune function. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200 |
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2015 Journal Article PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1aMcCarthy, Claudia A., Rash, Lachlan D., Chassagnon, Irene R., King, Glenn F. and Widdop, Robert E. (2015). PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a. Neuropharmacology, 99 5986, 650-657. doi: 10.1016/j.neuropharm.2015.08.040 |
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2015 Journal Article Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channelsCristofori-Armstrong, Ben, Soh, Ming S., Talwar, Sahil, Brown, Darren L., Griffin, John D. O., Dekan, Zoltan, Stow, Jennifer L., King, Glenn F., Lynch, Joseph W. and Rash, Lachlan D. (2015). Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels. Scientific Reports, 5 (1) 14763, 14763.1-14763.12. doi: 10.1038/srep14763 |
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2015 Journal Article Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1aSaez, Natalie J., Deplazes, Evelyne, Cristofori-Armstrong, Ben, Chassagnon, Irene R., Lin, Xiaozhen, Mobli, Mehdi, Mark, Alan E., Rash, Lachlan D. and King, Glenn F. (2015). Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a. British Journal of Pharmacology, 172 (20), 4985-4995. doi: 10.1111/bph.13267 |
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2015 Journal Article Widespread convergence in toxin resistance by predictable molecular evolutionUjvari, Beata, Casewell, Nicholas R., Sunagar, Kartik, Arbuckle, Kevin, Wuester, Wolfgang, Lo, Nathan, O'Meally, Denis, Beckmann, Christa, King, Glenn F., Deplazes, Evelyne and Madsen, Thomas (2015). Widespread convergence in toxin resistance by predictable molecular evolution. Proceedings of the National Academy of Sciences of the United States of America, 112 (38), 11911-11916. doi: 10.1073/pnas.1511706112 |
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2015 Journal Article Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriensCardoso, Fernanda C., Deka, Zoltan, Rosengren, K. Johan, Erickson, Andelain, Vetter, Irina, Deuis, Jennifer R., Herzig, Volker, Alewood, Paul F., King, Glenn F. and Lewis, Richard J. (2015). Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens. Molecular Pharmacology, 88 (2), 291-303. doi: 10.1124/mol.115.098178 |
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2015 Journal Article Weaponization of a hormone: convergent recruitment of hyperglycemic hormone into the venom of arthropod predatorsUndheim, Eivind A. B., Grimm, Lena L., Low, Chek -Fong, Morgenstern, David, Herzig, Volker, Zobel-Thropp, Pamela, Pineda, Sandy Steffany, Habib, Rosaline, Dziemborowicz, Slawomir, Fry, Bryan G., Nicholson, Graham M., Binford, Greta J., Mobli, Mehdi and King, Glenn F. (2015). Weaponization of a hormone: convergent recruitment of hyperglycemic hormone into the venom of arthropod predators. Structure, 23 (7) 3184, 1283-1292. doi: 10.1016/j.str.2015.05.003 |
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2015 Journal Article Three peptide modulators of the human voltage-gated sodium channel 1.7, an important analgesic target, from venom of an Australian tarantulaChow, Chun Yuen, Cristofori-Armstrong, Ben, Undheim, Eivind A. B., King, Glenn F. and Rash, Lachlan D. (2015). Three peptide modulators of the human voltage-gated sodium channel 1.7, an important analgesic target, from venom of an Australian tarantula. Toxins, 7 (7), 2494-2513. doi: 10.3390/toxins7072494 |
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2015 Journal Article Backbone and side chain NMR assignments of Geobacillus stearothermophilus ZapA allow identification of residues that mediate the interaction of ZapA with FtsZNogueira, Maria Luiza C., Sforca, Mauricio Luis, Chin, Yanni K. -Y., Mobli, Mehdi, Handler, Aaron, Gorbatyuk, Vitaliy Y., Robson, Scott A., King, Glenn F., Gueiros-Filho, Frederico J. and de Mattos Zeri, Ana Carolina (2015). Backbone and side chain NMR assignments of Geobacillus stearothermophilus ZapA allow identification of residues that mediate the interaction of ZapA with FtsZ. Biomolecular NMR Assignments, 9 (2), 387-391. doi: 10.1007/s12104-015-9615-1 |
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2015 Journal Article Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approachKlint, Julie K., Smith, Jennifer J., Vetter, Irina, Rupasinghe, Darshani B., Er, Sing Yan, Senff, Sebastian, Herzig, Volker, Mobli, Mehdi, Lewis, Richard J., Bosmans, Frank and King, Glenn F. (2015). Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approach. British Journal of Pharmacology, 172 (10), 2445-2458. doi: 10.1111/bph.13081 |
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2015 Journal Article Production and packaging of a biological arsenal: evolution of centipede venoms under morphological constraintUndheim, Eivind A.B., Hamilton, Brett R., Kurniawan, Nyoman D., Bowlay, Greg, Cribb, Bronwen W., Merritt, David J., Fry,Bryan G., King, Glenn F and Venter, Deon J. (2015). Production and packaging of a biological arsenal: evolution of centipede venoms under morphological constraint. PNAS: Proceedings of the National Academy of Sciences of the United States of America, 112 (13), 4026-4031. doi: 10.1073/pnas.1424068112 |
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2015 Journal Article RNA polymerase-induced remodelling of NusA produces a pause enhancement complexMa, Cong, Mobli, Mehdi, Yang, Xiao, Keller, Andrew N., King, Glenn F. and Lewis, Peter J. (2015). RNA polymerase-induced remodelling of NusA produces a pause enhancement complex. Nucleic Acids Research, 43 (5), 2829-2840. doi: 10.1093/nar/gkv108 |
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2015 Journal Article Safe and effective treatment of spontaneous neoplasms with interleukin 12 electro-chemo-gene therapyCutrera, Jeffry, King, Glenn, Jones, Pamela, Kicenuik, Kristin, Gumpel, Elias, Xia, Xueqing and Li, Shulin (2015). Safe and effective treatment of spontaneous neoplasms with interleukin 12 electro-chemo-gene therapy. Journal of Cellular and Molecular Medicine, 19 (3), 664-675. doi: 10.1111/jcmm.12382 |
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2015 Journal Article The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loopBende, Niraj S., Dziemborowicz, Slawomir, Herzig, Volker, Ramanujam, Venkatraman, Brown, Geoffrey W., Bosmans, Frank, Nicholson, Graham M., King, Glenn F. and Mobli, Mehdi (2015). The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop. FEBS Journal, 282 (5), 904-920. doi: 10.1111/febs.13189 |
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2015 Journal Article Centipede venom: Recent discoveries and current state of knowledgeUndheim, Eivind, Fry, Bryan and King, Glenn F (2015). Centipede venom: Recent discoveries and current state of knowledge. Toxins, 7 (3), 679-704. doi: 10.3390/toxins7030679 |
