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2018

Journal Article

Entomo-venomics: the evolution, biology and biochemistry of insect venoms

Walker, Andrew A., Robinson, Samuel D., Yeates, David K., Jin, Jiayi, Baumann, Kate, Dobson, James, Fry, Bryan G. and King, Glenn F. (2018). Entomo-venomics: the evolution, biology and biochemistry of insect venoms. Toxicon: official journal of the International Society on Toxinology, 154, 15-27. doi: 10.1016/j.toxicon.2018.09.004

Entomo-venomics: the evolution, biology and biochemistry of insect venoms

2018

Journal Article

1H, 13C and 15N NMR assignments of two plant protease inhibitors (IRD7 and IRD12) from the plant Capsicum annuum

Gartia, Janeka, Barnwal, Ravi Pratap, Anangi, Raveendra, Giri, Ashok R., King, Glenn and Chary, Kandala V. R. (2018). 1H, 13C and 15N NMR assignments of two plant protease inhibitors (IRD7 and IRD12) from the plant Capsicum annuum. Biomolecular NMR Assignments, 13 (1), 31-35. doi: 10.1007/s12104-018-9846-z

1H, 13C and 15N NMR assignments of two plant protease inhibitors (IRD7 and IRD12) from the plant Capsicum annuum

2018

Journal Article

A comprehensive portrait of the venom of the giant red bull ant, Myrmecia gulosa, reveals a hyperdiverse hymenopteran toxin gene family

Robinson, Samuel D., Mueller, Alexander, Clayton, Daniel, Starobova, Hana, Hamilton, Brett R., Payne, Richard J., Vetter, Irina, King, Glenn F. and Undheim, Eivind A. B. (2018). A comprehensive portrait of the venom of the giant red bull ant, Myrmecia gulosa, reveals a hyperdiverse hymenopteran toxin gene family. Science Advances, 4 (9) eaau4640, eaau4640. doi: 10.1126/sciadv.aau4640

A comprehensive portrait of the venom of the giant red bull ant, Myrmecia gulosa, reveals a hyperdiverse hymenopteran toxin gene family

2018

Conference Publication

From pain to pain-killers: using spider-venom peptides to help us understand and treat chronic pain

King, Glenn (2018). From pain to pain-killers: using spider-venom peptides to help us understand and treat chronic pain. HOBOKEN: WILEY.

From pain to pain-killers: using spider-venom peptides to help us understand and treat chronic pain

2018

Journal Article

Venoms to the rescue

Holford, Mande, Daly, Marymegan, King, Glenn F. and Norton, Raymond S. (2018). Venoms to the rescue. Science, 361 (6405), 842-844. doi: 10.1126/science.aau7761

Venoms to the rescue

2018

Journal Article

Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides

Herzig, Volker, de Araujo, Aline, Greenwood, Kathryn, Chin, Yanni, Windley, Monique, Chong, Youmie, Muttenthaler, Markus, Mobli, Mehdi, Audsley, Neil, Nicholson, Graham, Alewood, Paul and King, Glenn (2018). Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides. Biomedicines, 6 (3) 90, 90. doi: 10.3390/biomedicines6030090

Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides

2018

Journal Article

PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold

Madio, Bruno, Peigneur, Steve, Chin, Yanni K. Y., Hamilton, Brett R., Henriques, Sónia Troeira, Smith, Jennifer J., Cristofori-Armstrong, Ben, Dekan, Zoltan, Boughton, Berin A., Alewood, Paul F., Tytgat, Jan, King, Glenn F. and Undheim, Eivind A. B. (2018). PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold. Cellular and Molecular Life Sciences, 75 (24), 4511-4524. doi: 10.1007/s00018-018-2897-6

PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold

2018

Journal Article

Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death

Richards, Kay L., Milligan, Carol J., Richardson, Robert J., Jancovski, Nikola, Grunnet, Morten, Jacobson, Laura H., Undheim, Eivind A. B., Mobli, Mehdi, Chow, Chun Yuen, Herzig, Volker, Csoti, Agota, Panyi, Gyorgy, Reid, Christopher A., King, Glenn F. and Petrou, Steven (2018). Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death. Proceedings of the National Academy of Sciences, 115 (34), 201804764-E8085. doi: 10.1073/pnas.1804764115

Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death

2018

Journal Article

Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation

Ikonomopoulou, Maria P., Fernandez-Rojo, Manuel A., Pineda, Sandy S., Cabezas-Sainz, Pablo, Winnen, Brit, Morales, Rodrigo A. V., Brust, Andreas, Sanchez, Laura, Alewood, Paul F., Ramm, Grant A., Miles, John J. and King, Glenn F. (2018). Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. Scientific Reports, 8 (1) 11519, 11519. doi: 10.1038/s41598-018-29826-4

Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation

2018

Conference Publication

Role of voltage-gated sodium channel isoforms in colon-innervating neurons in mice

Erickson, A., Garcia-Caraballo, S., Castro, J., Grundy, L., Rychkov, G., Vetter, I., Lewis, R., King, G. and Brierley, S. (2018). Role of voltage-gated sodium channel isoforms in colon-innervating neurons in mice. HOBOKEN: WILEY.

Role of voltage-gated sodium channel isoforms in colon-innervating neurons in mice

2018

Journal Article

Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxins

Guo, Shaodong, Herzig, Volker and King, Glenn F. (2018). Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxins. Toxicon, 150, 297-303. doi: 10.1016/j.toxicon.2018.06.077

Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxins

2018

Journal Article

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

Shen, Huaizong, Li, Zhangqiang, Jiang, Yan, Pan, Xiaojing, Wu, Jianping, Cristofori-Armstrong, Ben, Smith, Jennifer J., Chin, Yanni K. Y., Lei, Jianlin, Zhou, Qiang, King, Glenn F. and Yan, Nieng (2018). Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Science, 362 (6412) eaau2596, eaau2596-+. doi: 10.1126/science.aau2596

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

2018

Journal Article

NaV1.1 inhibition can reduce visceral hypersensitivity

Salvatierra, Juan, Castro, Joel, Erickson, Andelain, Li, Qian, Braz, Joao, Gilchrist, John, Grundy, Luke, Rychkov, Grigori Y., Deiteren, Annemie, Rais, Rana, King, Glenn F., Slusher, Barbara S., Basbaum, Allan, Pasricha, Pankaj J., Brierley, Stuart M. and Bosmans, Frank (2018). NaV1.1 inhibition can reduce visceral hypersensitivity. JCI Insight, 3 (11) e121000. doi: 10.1172/jci.insight.121000

NaV1.1 inhibition can reduce visceral hypersensitivity

2018

Journal Article

Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane

Shivalingamurthy, Suresha G., Anangi, Raveendra, Kalaipandian, Sundaravelpandian, Glassop, Donna, King, Glenn F. and Rae, Anne L. (2018). Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane. Frontiers in Plant Science, 9 598, 598. doi: 10.3389/fpls.2018.00598

Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane

2018

Journal Article

Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes

Agwa, Akello J., Peigneur, Steve, Chow, Chun Yuen, Lawrence, Nicole, Craik, David J., Tytgat, Jan, King, Glenn F., Henriques, Sonia Troeira and Schroeder, Christina I. (2018). Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes. Journal of Biological Chemistry, 293 (23), 9041-9052. doi: 10.1074/jbc.RA118.002553

Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes

2018

Journal Article

Harvesting venom toxins from assassin bugs and other heteropteran insects

Walker, Andrew Allan, Rosenthal, Max, Undheim, Eivind E. A. and King, Glenn F (2018). Harvesting venom toxins from assassin bugs and other heteropteran insects. Journal of Visualized Experiments, 2018 (134) e57729. doi: 10.3791/57729

Harvesting venom toxins from assassin bugs and other heteropteran insects

2018

Journal Article

The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens

Walker, Andrew A., Mayhew, Mark L., Jin, Jiayi, Herzig, Volker, Undheim, Eivind A. B., Sombke, Andy, Fry, Bryan G., Meritt, David J. and King, Glenn F. (2018). The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens. Nature Communications, 9 (1) 755, 755. doi: 10.1038/s41467-018-03091-5

The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens

2018

Journal Article

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells

Fernandez-Rojo, Manuel A., Deplazes, Evelyne, Pineda, Sandy S., Brust, Andreas, Marth, Tano, Wilhelm, Patrick, Martel, Nick, Ramm, Grant A., Mancera, Ricardo L., Alewood, Paul F., Woods, Gregory M., Belov, Katherine, Miles, John J., King, Glenn F. and Ikonomopoulou, Maria P. (2018). Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery, 4 (1) 19, 19. doi: 10.1038/s41420-018-0030-0

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells

2018

Journal Article

Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera

Walker, Andrew A., Hernández-Vargas, Maria José, Corzo, Gerardo, Fry, Bryan G. and King, Glenn F. (2018). Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera. Cellular and Molecular Life Sciences, 75 (17), 1-15. doi: 10.1007/s00018-018-2768-1

Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera

2018

Journal Article

Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain

Lee, Jia Yu Peppermint, Saez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra, King, Glenn F., Smith, Maree T. and Rash, Lachlan D. (2018). Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain. British Journal of Pharmacology, 175 (12), 2204-2218. doi: 10.1111/bph.14089

Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain