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2018 Conference Publication From pain to pain-killers: using spider-venom peptides to help us understand and treat chronic painKing, Glenn (2018). From pain to pain-killers: using spider-venom peptides to help us understand and treat chronic pain. HOBOKEN: WILEY. |
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2018 Journal Article Venoms to the rescueHolford, Mande, Daly, Marymegan, King, Glenn F. and Norton, Raymond S. (2018). Venoms to the rescue. Science, 361 (6405), 842-844. doi: 10.1126/science.aau7761 |
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2018 Journal Article Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal PeptidesHerzig, Volker, de Araujo, Aline, Greenwood, Kathryn, Chin, Yanni, Windley, Monique, Chong, Youmie, Muttenthaler, Markus, Mobli, Mehdi, Audsley, Neil, Nicholson, Graham, Alewood, Paul and King, Glenn (2018). Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides. Biomedicines, 6 (3) 90, 90. doi: 10.3390/biomedicines6030090 |
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2018 Journal Article PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide foldMadio, Bruno, Peigneur, Steve, Chin, Yanni K. Y., Hamilton, Brett R., Henriques, Sónia Troeira, Smith, Jennifer J., Cristofori-Armstrong, Ben, Dekan, Zoltan, Boughton, Berin A., Alewood, Paul F., Tytgat, Jan, King, Glenn F. and Undheim, Eivind A. B. (2018). PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold. Cellular and Molecular Life Sciences, 75 (24), 4511-4524. doi: 10.1007/s00018-018-2897-6 |
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2018 Journal Article Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature deathRichards, Kay L., Milligan, Carol J., Richardson, Robert J., Jancovski, Nikola, Grunnet, Morten, Jacobson, Laura H., Undheim, Eivind A. B., Mobli, Mehdi, Chow, Chun Yuen, Herzig, Volker, Csoti, Agota, Panyi, Gyorgy, Reid, Christopher A., King, Glenn F. and Petrou, Steven (2018). Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death. Proceedings of the National Academy of Sciences, 115 (34), 201804764-E8085. doi: 10.1073/pnas.1804764115 |
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2018 Journal Article Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxinsGuo, Shaodong, Herzig, Volker and King, Glenn F. (2018). Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxins. Toxicon, 150, 297-303. doi: 10.1016/j.toxicon.2018.06.077 |
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2018 Journal Article Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferationIkonomopoulou, Maria P., Fernandez-Rojo, Manuel A., Pineda, Sandy S., Cabezas-Sainz, Pablo, Winnen, Brit, Morales, Rodrigo A. V., Brust, Andreas, Sanchez, Laura, Alewood, Paul F., Ramm, Grant A., Miles, John J. and King, Glenn F. (2018). Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. Scientific Reports, 8 (1) 11519, 11519. doi: 10.1038/s41598-018-29826-4 |
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2018 Conference Publication Role of voltage-gated sodium channel isoforms in colon-innervating neurons in miceErickson, A., Garcia-Caraballo, S., Castro, J., Grundy, L., Rychkov, G., Vetter, I., Lewis, R., King, G. and Brierley, S. (2018). Role of voltage-gated sodium channel isoforms in colon-innervating neurons in mice. HOBOKEN: WILEY. |
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2018 Journal Article Structural basis for the modulation of voltage-gated sodium channels by animal toxinsShen, Huaizong, Li, Zhangqiang, Jiang, Yan, Pan, Xiaojing, Wu, Jianping, Cristofori-Armstrong, Ben, Smith, Jennifer J., Chin, Yanni K. Y., Lei, Jianlin, Zhou, Qiang, King, Glenn F. and Yan, Nieng (2018). Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Science, 362 (6412) eaau2596, eaau2596-+. doi: 10.1126/science.aau2596 |
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2018 Journal Article NaV1.1 inhibition can reduce visceral hypersensitivitySalvatierra, Juan, Castro, Joel, Erickson, Andelain, Li, Qian, Braz, Joao, Gilchrist, John, Grundy, Luke, Rychkov, Grigori Y., Deiteren, Annemie, Rais, Rana, King, Glenn F., Slusher, Barbara S., Basbaum, Allan, Pasricha, Pankaj J., Brierley, Stuart M. and Bosmans, Frank (2018). NaV1.1 inhibition can reduce visceral hypersensitivity. JCI Insight, 3 (11) e121000. doi: 10.1172/jci.insight.121000 |
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2018 Journal Article Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcaneShivalingamurthy, Suresha G., Anangi, Raveendra, Kalaipandian, Sundaravelpandian, Glassop, Donna, King, Glenn F. and Rae, Anne L. (2018). Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane. Frontiers in Plant Science, 9 598, 598. doi: 10.3389/fpls.2018.00598 |
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2018 Journal Article Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranesAgwa, Akello J., Peigneur, Steve, Chow, Chun Yuen, Lawrence, Nicole, Craik, David J., Tytgat, Jan, King, Glenn F., Henriques, Sonia Troeira and Schroeder, Christina I. (2018). Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes. Journal of Biological Chemistry, 293 (23), 9041-9052. doi: 10.1074/jbc.RA118.002553 |
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2018 Journal Article Harvesting venom toxins from assassin bugs and other heteropteran insectsWalker, Andrew Allan, Rosenthal, Max, Undheim, Eivind E. A. and King, Glenn F (2018). Harvesting venom toxins from assassin bugs and other heteropteran insects. Journal of Visualized Experiments, 2018 (134) e57729. doi: 10.3791/57729 |
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2018 Journal Article The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumensWalker, Andrew A., Mayhew, Mark L., Jin, Jiayi, Herzig, Volker, Undheim, Eivind A. B., Sombke, Andy, Fry, Bryan G., Meritt, David J. and King, Glenn F. (2018). The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens. Nature Communications, 9 (1) 755, 755. doi: 10.1038/s41467-018-03091-5 |
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2018 Journal Article Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cellsFernandez-Rojo, Manuel A., Deplazes, Evelyne, Pineda, Sandy S., Brust, Andreas, Marth, Tano, Wilhelm, Patrick, Martel, Nick, Ramm, Grant A., Mancera, Ricardo L., Alewood, Paul F., Woods, Gregory M., Belov, Katherine, Miles, John J., King, Glenn F. and Ikonomopoulou, Maria P. (2018). Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery, 4 (1) 19, 19. doi: 10.1038/s41420-018-0030-0 |
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2018 Journal Article Giant fish-killing water bug reveals ancient and dynamic venom evolution in HeteropteraWalker, Andrew A., Hernández-Vargas, Maria José, Corzo, Gerardo, Fry, Bryan G. and King, Glenn F. (2018). Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera. Cellular and Molecular Life Sciences, 75 (17), 1-15. doi: 10.1007/s00018-018-2768-1 |
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2018 Journal Article Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory painLee, Jia Yu Peppermint, Saez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra, King, Glenn F., Smith, Maree T. and Rash, Lachlan D. (2018). Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain. British Journal of Pharmacology, 175 (12), 2204-2218. doi: 10.1111/bph.14089 |
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2018 Conference Publication The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitorsSchroeder, Christina, Agwa, Akello, Mueller, Alexander, Chow, Chun Yuen, Peigneur, Steve, Lawrence, Nicole, Deplazes, Evelyne, Mark, Alan, Craik, David, Tytgat, Jan, King, Glenn, Vetter, Irina and Henriques, Sonia Troeira (2018). The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons. |
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2018 Conference Publication Margatoxin-conjugated quantum dots as a tool for targeted inhibition of the voltage-gated potassium channel Kv1.3 in the olfactory bulbSchwartz, Austin B., Kapur, Anshika, Huang, Zhenbo, Anangi, Raveendra, Deklan, Zoltan, Fardone, Erminia, Palui, Goutam, King, Glenn F., Mattoussi, Hedi and Fadool, Debra A. (2018). Margatoxin-conjugated quantum dots as a tool for targeted inhibition of the voltage-gated potassium channel Kv1.3 in the olfactory bulb. 39th Annual Meeting of the Association for Chemoreception Sciences (AChemS), Bonita Springs, FL, United States, 26-29 April 2017. Oxford, United Kingdom: Oxford University Press . |
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2018 Conference Publication Counter screen of spider venoms reveals novel sodium and calcium channel inhibitors of chronic pain targets.Cardoso, F. C., Herzig, V., King, G. F. and Lewis, R. J. (2018). Counter screen of spider venoms reveals novel sodium and calcium channel inhibitors of chronic pain targets.. Gordon Research Conference on Venom Evolution, Function and Biomedical Applications 2018, Mount Snow, VT, United States, 5-10 August 2018. |
