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2018

Journal Article

Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxins

Guo, Shaodong, Herzig, Volker and King, Glenn F. (2018). Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxins. Toxicon, 150, 297-303. doi: 10.1016/j.toxicon.2018.06.077

Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxins

2018

Journal Article

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

Shen, Huaizong, Li, Zhangqiang, Jiang, Yan, Pan, Xiaojing, Wu, Jianping, Cristofori-Armstrong, Ben, Smith, Jennifer J., Chin, Yanni K. Y., Lei, Jianlin, Zhou, Qiang, King, Glenn F. and Yan, Nieng (2018). Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Science, 362 (6412) eaau2596, eaau2596-+. doi: 10.1126/science.aau2596

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

2018

Journal Article

NaV1.1 inhibition can reduce visceral hypersensitivity

Salvatierra, Juan, Castro, Joel, Erickson, Andelain, Li, Qian, Braz, Joao, Gilchrist, John, Grundy, Luke, Rychkov, Grigori Y., Deiteren, Annemie, Rais, Rana, King, Glenn F., Slusher, Barbara S., Basbaum, Allan, Pasricha, Pankaj J., Brierley, Stuart M. and Bosmans, Frank (2018). NaV1.1 inhibition can reduce visceral hypersensitivity. JCI Insight, 3 (11) e121000. doi: 10.1172/jci.insight.121000

NaV1.1 inhibition can reduce visceral hypersensitivity

2018

Journal Article

Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane

Shivalingamurthy, Suresha G., Anangi, Raveendra, Kalaipandian, Sundaravelpandian, Glassop, Donna, King, Glenn F. and Rae, Anne L. (2018). Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane. Frontiers in Plant Science, 9 598, 598. doi: 10.3389/fpls.2018.00598

Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane

2018

Journal Article

Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes

Agwa, Akello J., Peigneur, Steve, Chow, Chun Yuen, Lawrence, Nicole, Craik, David J., Tytgat, Jan, King, Glenn F., Henriques, Sonia Troeira and Schroeder, Christina I. (2018). Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes. Journal of Biological Chemistry, 293 (23), 9041-9052. doi: 10.1074/jbc.RA118.002553

Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes

2018

Journal Article

Harvesting venom toxins from assassin bugs and other heteropteran insects

Walker, Andrew Allan, Rosenthal, Max, Undheim, Eivind E. A. and King, Glenn F (2018). Harvesting venom toxins from assassin bugs and other heteropteran insects. Journal of Visualized Experiments, 2018 (134) e57729. doi: 10.3791/57729

Harvesting venom toxins from assassin bugs and other heteropteran insects

2018

Journal Article

The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens

Walker, Andrew A., Mayhew, Mark L., Jin, Jiayi, Herzig, Volker, Undheim, Eivind A. B., Sombke, Andy, Fry, Bryan G., Meritt, David J. and King, Glenn F. (2018). The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens. Nature Communications, 9 (1) 755, 755. doi: 10.1038/s41467-018-03091-5

The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens

2018

Journal Article

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells

Fernandez-Rojo, Manuel A., Deplazes, Evelyne, Pineda, Sandy S., Brust, Andreas, Marth, Tano, Wilhelm, Patrick, Martel, Nick, Ramm, Grant A., Mancera, Ricardo L., Alewood, Paul F., Woods, Gregory M., Belov, Katherine, Miles, John J., King, Glenn F. and Ikonomopoulou, Maria P. (2018). Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery, 4 (1) 19, 19. doi: 10.1038/s41420-018-0030-0

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells

2018

Journal Article

Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera

Walker, Andrew A., Hernández-Vargas, Maria José, Corzo, Gerardo, Fry, Bryan G. and King, Glenn F. (2018). Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera. Cellular and Molecular Life Sciences, 75 (17), 1-15. doi: 10.1007/s00018-018-2768-1

Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera

2018

Journal Article

Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain

Lee, Jia Yu Peppermint, Saez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra, King, Glenn F., Smith, Maree T. and Rash, Lachlan D. (2018). Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain. British Journal of Pharmacology, 175 (12), 2204-2218. doi: 10.1111/bph.14089

Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain

2018

Conference Publication

Counter screen of spider venoms reveals novel sodium and calcium channel inhibitors of chronic pain targets.

Cardoso, F. C., Herzig, V., King, G. F. and Lewis, R. J. (2018). Counter screen of spider venoms reveals novel sodium and calcium channel inhibitors of chronic pain targets.. Gordon Research Conference on Venom Evolution, Function and Biomedical Applications 2018, Mount Snow, VT, United States, 5-10 August 2018.

Counter screen of spider venoms reveals novel sodium and calcium channel inhibitors of chronic pain targets.

2018

Conference Publication

Development and application of a peptide inhibitor-bound quantum dot targeting the voltage-gated potassium channel Kv1.3 in the olfactory bulb

Schwartz, Austin B., Kapur, Anshika, Huang, Zhenbo, Anangi, Raveendra, Dekan, Zoltan, Fardone, Erminia, Palui, Goutam, King, Glenn F., Mattoussi, Hedi and Fadool, Debra A. (2018). Development and application of a peptide inhibitor-bound quantum dot targeting the voltage-gated potassium channel Kv1.3 in the olfactory bulb. 62nd Annual Meeting of the Biophysical Society, San Francisco, CA, United States, 17-21 February 2018. St. Louis, MO, United States : Cell Press. doi: 10.1016/j.bpj.2017.11.1753

Development and application of a peptide inhibitor-bound quantum dot targeting the voltage-gated potassium channel Kv1.3 in the olfactory bulb

2018

Conference Publication

Bug off pain: probing P2X channels with venoms

Bibic, L., Herzig, V., King, G. F., Ma, L., Chow, C. Y. and Stokes, L. (2018). Bug off pain: probing P2X channels with venoms. Purines 2018 Basic and Translational Science on Purinergic Signaling and its Components for a Healthy and Better World, Foz do Iguaçu, Brazil, 19-22 June 2018. Dordrecht, Netherlands: Springer.

Bug off pain: probing P2X channels with venoms

2018

Conference Publication

The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors

Schroeder, Christina, Agwa, Akello, Mueller, Alexander, Chow, Chun Yuen, Peigneur, Steve, Lawrence, Nicole, Deplazes, Evelyne, Mark, Alan, Craik, David, Tytgat, Jan, King, Glenn, Vetter, Irina and Henriques, Sonia Troeira (2018). The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons.

The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors

2018

Conference Publication

Margatoxin-conjugated quantum dots as a tool for targeted inhibition of the voltage-gated potassium channel Kv1.3 in the olfactory bulb

Schwartz, Austin B., Kapur, Anshika, Huang, Zhenbo, Anangi, Raveendra, Deklan, Zoltan, Fardone, Erminia, Palui, Goutam, King, Glenn F., Mattoussi, Hedi and Fadool, Debra A. (2018). Margatoxin-conjugated quantum dots as a tool for targeted inhibition of the voltage-gated potassium channel Kv1.3 in the olfactory bulb. 39th Annual Meeting of the Association for Chemoreception Sciences (AChemS), Bonita Springs, FL, United States, 26-29 April 2017. Oxford, United Kingdom: Oxford University Press .

Margatoxin-conjugated quantum dots as a tool for targeted inhibition of the voltage-gated potassium channel Kv1.3 in the olfactory bulb

2017

Journal Article

The North American Society of Toxinology establishes formal affiliation with Toxicon

Keyler, Daniel E. and King, Glenn F. (2017). The North American Society of Toxinology establishes formal affiliation with Toxicon. Toxicon, 142, A1-A1. doi: 10.1016/j.toxicon.2017.11.009

The North American Society of Toxinology establishes formal affiliation with Toxicon

2017

Journal Article

ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins

Pineda, Sandy S., Chaumeil, Pierre-Alain, Kunert, Anne, Kaas, Quentin, Thang, Mike W. C., Le, Lien, Nuhn, Michael, Herzig, Volker, Saez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra, Senff, Sebastian, Gorse, Dominique and King, Glenn F. (2017). ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins. Bioinformatics, 34 (6), 1074-1076. doi: 10.1093/bioinformatics/btx661

ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins

2017

Journal Article

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

Sousa, Silmara R., Wingerd, Joshua S., Brust, Andreas, Bladen, Christopher, Ragnarsson, Lotten, Herzig, Volker, Deuis, Jennifer R., Dutertre, Sebastien, Vetter, Irina, Zamponi, Gerald W., King, Glenn F., Alewood, Paul F. and Lewis, Richard J. (2017). Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi. PLoS One, 12 (9) e0182848, e0182848. doi: 10.1371/journal.pone.0182848

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

2017

Journal Article

Revisiting venom of the sea anemone Stichodactyla haddoni: omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus

Madio, Bruno, Undheim, Eivind A. B. and King, Glenn F. (2017). Revisiting venom of the sea anemone Stichodactyla haddoni: omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus. Journal of Proteomics, 166, 83-92. doi: 10.1016/j.jprot.2017.07.007

Revisiting venom of the sea anemone Stichodactyla haddoni: omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus

2017

Journal Article

Improved efficacy of an arthropod toxin expressing fungus against insecticide-resistant malaria-vector mosquitoes

Bilgo, Etienne, Lovett, Brian, Fang, Weiguo, Bende, Niraj, King, Glenn F., Diabate, Abdoulaye and St Leger, Raymond J. (2017). Improved efficacy of an arthropod toxin expressing fungus against insecticide-resistant malaria-vector mosquitoes. Scientific Reports, 7 (1) 3433, 3433. doi: 10.1038/s41598-017-03399-0

Improved efficacy of an arthropod toxin expressing fungus against insecticide-resistant malaria-vector mosquitoes