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2023

Journal Article

Evaluation of peptide ligation strategies for the synthesis of the bivalent acid-sensing ion channel inhibitor Hi1a

Tran, Hue N. T., Budusan, Elena, Saez, Natalie J., Norman, Alexander, Tucker, Isaac J., King, Glenn F., Payne, Richard J., Rash, Lachlan D., Vetter, Irina and Schroeder, Christina I. (2023). Evaluation of peptide ligation strategies for the synthesis of the bivalent acid-sensing ion channel inhibitor Hi1a. Organic Letters, 25 (24), 4439-4444. doi: 10.1021/acs.orglett.3c01346

Evaluation of peptide ligation strategies for the synthesis of the bivalent acid-sensing ion channel inhibitor Hi1a

2023

Journal Article

The β3‐subunit modulates the effect of venom peptides ProTx‐II and OD1 on NaV 1.7 gating

Salvage, Samantha C., Rahman, Taufiq, Eagles, David A., Rees, Johanna S., King, Glenn F., Huang, Christopher L‐H. and Jackson, Antony P. (2023). The β3‐subunit modulates the effect of venom peptides ProTx‐II and OD1 on NaV 1.7 gating. Journal of Cellular Physiology, 238 (6), 1354-1367. doi: 10.1002/jcp.31018

The β3‐subunit modulates the effect of venom peptides ProTx‐II and OD1 on NaV 1.7 gating

2023

Journal Article

Ant venoms contain vertebrate-selective pain-causing sodium channel toxins

Robinson, Samuel D., Deuis, Jennifer R., Touchard, Axel, Keramidas, Angelo, Mueller, Alexander, Schroeder, Christina I., Barassé, Valentine, Walker, Andrew A., Brinkwirth, Nina, Jami, Sina, Bonnafé, Elsa, Treilhou, Michel, Undheim, Eivind A. B., Schmidt, Justin O., King, Glenn F. and Vetter, Irina (2023). Ant venoms contain vertebrate-selective pain-causing sodium channel toxins. Nature Communications, 14 (1) 2977, 1-11. doi: 10.1038/s41467-023-38839-1

Ant venoms contain vertebrate-selective pain-causing sodium channel toxins

2023

Journal Article

New drug targets and preclinical modelling recommendations for treating acute myocardial infarction

Cao, Yuanzhao, Redd, Meredith A., Fang, Chen, Mizikovsky, Dalia, Li, Xichun, Macdonald, Peter S., King, Glenn F. and Palpant, Nathan J. (2023). New drug targets and preclinical modelling recommendations for treating acute myocardial infarction. Heart, Lung and Circulation, 32 (7), 852-869. doi: 10.1016/j.hlc.2022.12.015

New drug targets and preclinical modelling recommendations for treating acute myocardial infarction

2023

Conference Publication

Improving asystolic warm ischemic time tolerance in donation after circulatory death donor hearts

Joshi, Y., Villanueva, J., Gao, L., Hwang, B., Wang, K., Kasavaraj, A., Doyle, A., Wu, J., Palpant, N., King, G., Iyer, A., Jansz, P. and MacDonald, P. (2023). Improving asystolic warm ischemic time tolerance in donation after circulatory death donor hearts. 43rd Annual Meeting of International Society for Heart and Lung Transplantation (ISHLT), Denver, CO United States, 19-22 April 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2023.02.878

Improving asystolic warm ischemic time tolerance in donation after circulatory death donor hearts

2023

Journal Article

Genetic or pharmacological ablation of acid-sensing ion channel 1a (ASIC1a) is not neuroprotective in a mouse model of spinal cord injury

Foster, Victoria, Saez, Natalie, Gillespie, Ellen, Jogia, Trisha, Reid, Chantelle, Maljevic, Snezana, Jung, Woncheol, Lao, Hong W., Ruitenberg, Marc Jan and King, Glen (2023). Genetic or pharmacological ablation of acid-sensing ion channel 1a (ASIC1a) is not neuroprotective in a mouse model of spinal cord injury. Journal of Neurotrauma, 41 (9-10), 1007-1019. doi: 10.1089/neu.2022.0295

Genetic or pharmacological ablation of acid-sensing ion channel 1a (ASIC1a) is not neuroprotective in a mouse model of spinal cord injury

2023

Journal Article

The voltage‐gated sodium channel NaV 1 .7 underlies endometriosis‐associated chronic pelvic pain

Castro, Joel, Maddern, Jessica, Chow, Chun Yuen, Tran, Poanna, Vetter, Irina, King, Glenn F. and Brierley, Stuart M. (2023). The voltage‐gated sodium channel NaV 1 .7 underlies endometriosis‐associated chronic pelvic pain. Journal of Neurochemistry, 168 (11), 3760-3776. doi: 10.1111/jnc.15795

The voltage‐gated sodium channel NaV 1 .7 underlies endometriosis‐associated chronic pelvic pain

2023

Journal Article

Holistic profiling of the venom from the Brazilian wandering spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

Cardoso, F. C., Walker, A. A., King, G. F. and Gomez, M. V. (2023). Holistic profiling of the venom from the Brazilian wandering spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics. Frontiers in Molecular Biosciences, 10 1069764, 1069764. doi: 10.3389/fmolb.2023.1069764

Holistic profiling of the venom from the Brazilian wandering spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

2023

Journal Article

Intra-colony venom diversity contributes to maintaining eusociality in a cooperatively breeding ant

Robinson, Samuel D., Schendel, Vanessa, Schroeder, Christina I., Moen, Sarah, Mueller, Alexander, Walker, Andrew A., McKinnon, Naomi, Neely, G. Gregory, Vetter, Irina, King, Glenn F. and Undheim, Eivind A. B. (2023). Intra-colony venom diversity contributes to maintaining eusociality in a cooperatively breeding ant. BMC Biology, 21 (1) 5, 5. doi: 10.1186/s12915-022-01507-9

Intra-colony venom diversity contributes to maintaining eusociality in a cooperatively breeding ant

2022

Journal Article

Composition and toxicity of venom produced by araneophagous white-tailed spiders (Lamponidae: Lampona sp.)

Michálek, Ondřej, Walker, Andrew A., Šedo, Ondrej, Zdráhal, Zbyněk, King, Glenn F. and Pekár, Stano (2022). Composition and toxicity of venom produced by araneophagous white-tailed spiders (Lamponidae: Lampona sp.). Scientific Reports, 12 (1) 21597, 1-13. doi: 10.1038/s41598-022-24694-5

Composition and toxicity of venom produced by araneophagous white-tailed spiders (Lamponidae: Lampona sp.)

2022

Journal Article

Venom composition and pain-causing toxins of the Australian great carpenter bee Xylocopa aruana

Shi, Naiqi, Szanto, Tibor G., He, Jia, Schroeder, Christina I., Walker, Andrew A., Deuis, Jennifer R., Vetter, Irina, Panyi, György, King, Glenn F. and Robinson, Samuel D. (2022). Venom composition and pain-causing toxins of the Australian great carpenter bee Xylocopa aruana. Scientific Reports, 12 (1) 22168, 1-13. doi: 10.1038/s41598-022-26867-8

Venom composition and pain-causing toxins of the Australian great carpenter bee Xylocopa aruana

2022

Journal Article

Holistic profiling of the venom from the lethal spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

Cardoso, Fernanda C., Walker, Andrew A., King, Glenn F. and Gomez, Marcus V. (2022). Holistic profiling of the venom from the lethal spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics.

Holistic profiling of the venom from the lethal spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

2022

Journal Article

The deadly toxin arsenal of the tree-dwelling Australian funnel-web spiders

Cardoso, Fernanda C., Pineda, Sandy S., Herzig, Volker, Sunagar, Kartik, Shaikh, Naeem Yusuf, Jin, Ai-Hua, King, Glenn F., Alewood, Paul F., Lewis, Richard J. and Dutertre, Sébastien (2022). The deadly toxin arsenal of the tree-dwelling Australian funnel-web spiders. International Journal of Molecular Sciences, 23 (21) 13077, 13077. doi: 10.3390/ijms232113077

The deadly toxin arsenal of the tree-dwelling Australian funnel-web spiders

2022

Journal Article

The structural conformation of the tachykinin domain drives the anti‐tumoral activity of an octopus peptide in melanoma BRAF <sup>V600E</sup>

Moral‐Sanz, Javier, Fernandez‐Rojo, Manuel A., Colmenarejo, Gonzalo, Kurdyukov, Sergey, Brust, Andreas, Ragnarsson, Lotten, Andersson, Åsa, Vila, Sabela F., Cabezas‐Sainz, Pablo, Wilhelm, Patrick, Vela‐Sebastian, Ana, Fernández‐Carrasco, Isabel, Chin, Yanni K. Y., López‐ Mancheño, Yaiza, Smallwood, Taylor B., Clark, Richard J., Fry, Bryan G., King, Glenn F., Ramm, Grant A., Alewood, Paul F., Lewis, Richard J., Mulvenna, Jason P., Boyle, Glen M., Sanchez, Laura E., Neely, G. Gregory, Miles, John J. and Ikonomopoulou, Maria P. (2022). The structural conformation of the tachykinin domain drives the anti‐tumoral activity of an octopus peptide in melanoma BRAF V600E. British Journal of Pharmacology, 179 (20), 4878-4896. doi: 10.1111/bph.15923

The structural conformation of the tachykinin domain drives the anti‐tumoral activity of an octopus peptide in melanoma BRAF <sup>V600E</sup>

2022

Conference Publication

Structure, function, and evolution of nettle caterpillar venom toxins

Goudarzi, Mohaddeseh H., Robinson, Samuel D., Cardoso, Fernanda C., Lawrence, Nicole, Chin, Yanni, King, Glenn F. and Walker, Andrew A. (2022). Structure, function, and evolution of nettle caterpillar venom toxins. Pathogens and Natural Toxins e-Conference, Brisbane, QLD Australia, 1 July - 31 August 2022.

Structure, function, and evolution of nettle caterpillar venom toxins

2022

Journal Article

The tarantula toxin ω-Avsp1a specifically inhibits human CaV3.1 and CaV3.3 via the extracellular S3-S4 loop of the domain 1 voltage-sensor

Herzig, Volker, Chen, Yong-Cyuan, Chin, Yanni K.-Y., Dekan, Zoltan, Chang, Yu-Wang, Yu, Hui-Ming, Alewood, Paul F., Chen, Chien-Chang and King, Glenn F. (2022). The tarantula toxin ω-Avsp1a specifically inhibits human CaV3.1 and CaV3.3 via the extracellular S3-S4 loop of the domain 1 voltage-sensor. Biomedicines, 10 (5) 1066, 1066. doi: 10.3390/biomedicines10051066

The tarantula toxin ω-Avsp1a specifically inhibits human CaV3.1 and CaV3.3 via the extracellular S3-S4 loop of the domain 1 voltage-sensor

2022

Journal Article

Proteotranscriptomics reveals the secretory dynamics of teratocytes, regulators of parasitization by an endoparasitoid wasp

Pinto, Ciro P.G., Walker, Andrew A., Robinson, Samuel D., King, Glenn F. and Rossi, Guilherme D. (2022). Proteotranscriptomics reveals the secretory dynamics of teratocytes, regulators of parasitization by an endoparasitoid wasp. Journal of Insect Physiology, 139 104395, 104395. doi: 10.1016/j.jinsphys.2022.104395

Proteotranscriptomics reveals the secretory dynamics of teratocytes, regulators of parasitization by an endoparasitoid wasp

2022

Journal Article

Cysteine-rich α-conotoxin SII displays novel interactions at the muscle nicotinic acetylcholine receptor

Wilhelm, Patrick, Luna-Ramirez, Karen, Chin, Yanni K.-Y., Dekan, Zoltan, Abraham, Nikita, Tae, Han-Shen, Chow, Chun Yuen, Eagles, David A., King, Glenn F., Lewis, Richard J., Adams, David J. and Alewood, Paul F. (2022). Cysteine-rich α-conotoxin SII displays novel interactions at the muscle nicotinic acetylcholine receptor. ACS Chemical Neuroscience, 13 (8), 1245-1250. doi: 10.1021/acschemneuro.1c00857

Cysteine-rich α-conotoxin SII displays novel interactions at the muscle nicotinic acetylcholine receptor

2022

Journal Article

A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals

Eagles, David A., Saez, Natalie J., Krishnarjuna, Bankala, Bradford, Julia J., Chin, Yanni K.-Y., Starobova, Hana, Mueller, Alexander, Reichelt, Melissa E., Undheim, Eivind A. B., Norton, Raymond S., Thomas, Walter G., Vetter, Irina, King, Glenn F. and Robinson, Samuel D. (2022). A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals. Proceedings of the National Academy of Sciences, 119 (7) e2112630119. doi: 10.1073/pnas.2112630119

A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals

2022

Journal Article

Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider

Finol-Urdaneta, Rocio K., Ziegman, Rebekah, Dekan, Zoltan, McArthur, Jeffrey R., Heitmann, Stewart, Luna-Ramirez, Karen, Tae, Han-Shen, Mueller, Alexander, Starobova, Hana, Chin, Yanni K.-Y., Wingerd, Joshua S., Undheim, Eivind A. B., Cristofori-Armstrong, Ben, Hill, Adam P., Herzig, Volker, King, Glenn F., Vetter, Irina, Rash, Lachlan D., Adams, David J. and Alewood, Paul F. (2022). Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider. Proceedings of the National Academy of Sciences, 119 (5) e2110932119. doi: 10.1073/pnas.2110932119

Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider