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2019 Journal Article amdS as a dominant recyclable marker in Cryptococcus neoformansErpf, Paige E., Stephenson, Christina J. and Fraser, James A. (2019). amdS as a dominant recyclable marker in Cryptococcus neoformans. Fungal Genetics and Biology, 131 103241, 103241. doi: 10.1016/j.fgb.2019.103241 |
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2019 Journal Article MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibitionColl, Rebecca C., Hill, James R., Day, Christopher J., Zamoshnikova, Alina, Boucher, Dave, Massey, Nicholas L., Chitty, Jessica L., Fraser, James A., Jennings, Michael P., Robertson, Avril A. B. and Schroder, Kate (2019). MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition. Nature Chemical Biology, 15 (6), 556-559. doi: 10.1038/s41589-019-0277-7 |
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2019 Journal Article Quantitation of Purines from Pigeon Guano and Implications for Cryptococcus neoformans Survival During InfectionChitty, Jessica L., Edwards, David J., Robertson, Avril A. B., Butler, Mark S., Duley, John A., Cooper, Matthew A. and Fraser, James A. (2019). Quantitation of Purines from Pigeon Guano and Implications for Cryptococcus neoformans Survival During Infection. Mycopathologia, 184 (2), 273-281. doi: 10.1007/s11046-018-0315-0 |
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2018 Journal Article Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infectionsGarcia, Mario D., Chua, Sheena M. H., Low, Yu-Shang, Lee, Yu-Ting, Agnew-Francis, Kylie, Wang, Jian-Guo, Nouwens, Amanda, Lonhienne, Thierry, Williams, Craig M., Fraser, James A. and Guddat, Luke W. (2018). Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proceedings of the National Academy of Sciences of the United States of America, 115 (41), E9649-E9658. doi: 10.1073/pnas.1809422115 |
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2018 Journal Article Cell Wall and Whole Cell Proteomes Define Flocculation and Fermentation Behavior of YeastKerr, Edward, McDiarmid, Duin, Fraser, James and Schulz, Benjamin (2018). Cell Wall and Whole Cell Proteomes Define Flocculation and Fermentation Behavior of Yeast. Fermentation, 4 (3) 80, 80. doi: 10.3390/fermentation4030080 |
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2018 Journal Article Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profilesKummari, Lalith K., Butler, Mark S., Furlong, Emily, Blundell, Ross, Nouwens, Amanda, Silva, Alberto B., Kappler, Ulrike, Fraser, James A., Kobe, Bostjan, Cooper, Matthew A. and Robertson, Avril A.B. (2018). Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles. Bioorganic and Medicinal Chemistry, 26 (20), 5408-5419. doi: 10.1016/j.bmc.2018.09.004 |
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2018 Journal Article Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulatorsHommel, Benjamin, Mukaremera, Liliane, Cordero, Radames J. B., Coelho, Carolina, Desjardins, Christopher A., Sturny-Leclère, Aude, Janbon, Guilhem, Perfect, John R., Fraser, James A., Casadevall, Arturo, Cuomo, Christina A., Dromer, Françoise, Nielsen, Kirsten and Alanio, Alexandre (2018). Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators. PLoS Pathogens, 14 (5) e1006982, e1006982. doi: 10.1371/journal.ppat.1006982 |
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2018 Journal Article The beer and biofuels laboratory: a report on implementing and supporting a large, interdisciplinary, yeast-focused course-based undergraduate research experiencePedwell, Rhianna K., Fraser, James A., Wang, Jack T. H., Clegg, Jack K., Chartres, Jy D. and Rowland, Susan L. (2018). The beer and biofuels laboratory: a report on implementing and supporting a large, interdisciplinary, yeast-focused course-based undergraduate research experience. Biochemistry and Molecular Biology Education , 46 (3), 213-222. doi: 10.1002/bmb.21111 |
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2018 Journal Article The long history of the diverse roles of short ORFs: sPEPs in fungiErpf, Paige E. and Fraser, James A. (2018). The long history of the diverse roles of short ORFs: sPEPs in fungi. Proteomics, 18 (10) 1700219, e1700219. doi: 10.1002/pmic.201700219 |
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2017 Journal Article High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanismLonhienne, Thierry, Garcia, Mario D., Noble, Chris, Harmer, Jeffrey, Fraser, James A., Williams, Craig M. and Guddat, Luke W. (2017). High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism. Chemistryselect, 2 (36), 11981-11988. doi: 10.1002/slct.201702128 |
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2017 Journal Article Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinicArras, Samantha D. M., Ormerod, Kate L., Erpf, Paige E., Espinosa, Monica I., Carpenter, Alex C., Blundell, Ross D., Stowasser, Samantha R., Schulz, Benjamin L., Tanurdzic, Milos and Fraser, James A. (2017). Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic. Scientific Reports, 7 (1) 17918, 1-14. doi: 10.1038/s41598-017-18106-2 |
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2017 Journal Article Antimicrobial octapeptin C4 analogues active against Cryptococcus speciesChitty, Jessica L., Butler, Mark S., Suboh, Azzah, Edwards, David J., Cooper, Matthew A., Fraser, James A. and Robertson, Avril A. B. (2017). Antimicrobial octapeptin C4 analogues active against Cryptococcus species. Antimicrobial agents and chemotherapy, 62 (2) e00986-17, 1-10. doi: 10.1128/AAC.00986-17 |
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2017 Journal Article A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genomeUpadhya, Rajendra, Lam, Woei C., Maybruck, Brian T., Donlin, Maureen J., Chang, Andrew L., Kayode, Sarah, Ormerod, Kate L., Fraser, James A., Doering, Tamara L. and Lodge, Jennifer K. (2017). A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome. Fungal Genetics and Biology : FG & B, 108, 13-25. doi: 10.1016/j.fgb.2017.08.008 |
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2017 Journal Article Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug designChitty, Jessica L., Blake, Kirsten L., Blundell, Ross D., Koh, Y. Q. Andre E., Thompson, Merinda, Robertson, Avril A. B., Butler, Mark S., Cooper, Matthew A., Kappler, Ulrike, Williams, Simon J., Kobe, Bostjan and Fraser, James A. (2017). Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design. Journal of Biological Chemistry, 292 (28), 11829-11839. doi: 10.1074/jbc.M117.787994 |
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2017 Journal Article Importance of resolving fungal nomenclature: the case of multiple pathogenic species in the Cryptococcus genusHagen, Ferry, Lumbsch, H. Thorsten, Arsenijevic, Valentina Arsic, Badali, Hamid, Bertout, Sebastien, Billmyre, R. Blake, Rosa Bragulat, M., Javier Cabanes, F., Carbia, Mauricio, Chakrabarti, Arunaloke, Chaturvedi, Sudha, Chaturvedi, Vishnu, Chen, Min, Chowdhary, Anuradha, Colom, Maria-Francisca, Cornely, Oliver A., Crous, Pedro W., Cuetara, Maria S., Diaz, Mara R., Espinel-Ingroff, Ana, Fakhim, Hamed, Falk, Rama, Fang, Wenjie, Herkert, Patricia F., Ferrer Rodriguez, Consuelo, Fraser, James A., Gene, Josepa, Guarro, Josep, Idnurm, Alexander ... Boekhoutiii, Teun (2017). Importance of resolving fungal nomenclature: the case of multiple pathogenic species in the Cryptococcus genus. Msphere, 2 (4) e00238-17. doi: 10.1128/mSphere.00238-17 |
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2017 Journal Article Purine acquisition and synthesis by human fungal pathogensChitty, Jessica L. and Fraser, James A. (2017). Purine acquisition and synthesis by human fungal pathogens. Microorganisms, 5 (2) 33, 33.1-33.16. doi: 10.3390/microorganisms5020033 |
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2017 Journal Article Sirtuins in the phylum Basidiomycota: A role in virulence in Cryptococcus neoformansArras, Samantha D. M., Chitty, Jessica L., Wizrah, Maha S. I., Erpf, Paige E., Schulz, Benjamin L., Tanurdzic, Milos and Fraser, James A. (2017). Sirtuins in the phylum Basidiomycota: A role in virulence in Cryptococcus neoformans. Scientific Reports, 7 (1) 46567, 46567.1-46567.14. doi: 10.1038/srep46567 |
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2017 Journal Article GMP synthase is required for virulence factor production and infection by cryptococcus neoformansChitty, Jessica L., Tatzenko, Tayla L. , Williams, Simon J., Koh, Y. Q. Andre E., Corfield, Elizabeth C., Butler, Mark S., Robertson, Avril A. B., Cooper, Matthew A., Kappler, Ulrike, Kobe, Bostjan and Fraser, James A. (2017). GMP synthase is required for virulence factor production and infection by cryptococcus neoformans. Journal of Biological Chemistry, 292 (7), 3049-3059. doi: 10.1074/jbc.M116.767533 |
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2017 Journal Article The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirementsLonhienne, Thierry, Garcia, Mario D., Fraser, James A., Williams, Craig M. and Guddat, Luke W. (2017). The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements. PLoS One, 12 (2) e0171443, e0171443.1-e0171443.13. doi: 10.1371/journal.pone.0171443 |
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2017 Journal Article Corrigendum: Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of CommercialWine Strains of Saccharomyces cerevisiae [G3 Genes|Genomes|Genetics, 6 (957-971)]Borneman, A. R., Forgan, A.H., Kolouchova, R., Fraser, J. A. and Schmidt, S.A. (2017). Corrigendum: Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of CommercialWine Strains of Saccharomyces cerevisiae [G3 Genes|Genomes|Genetics, 6 (957-971)]. G3: Genes, Genomes, Genetics, 7 (1), 319-319. doi: 10.1534/g3.116.036038 |
