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2025

Journal Article

Deciphering the functions of Spt20 in the SAGA complex: Implications for Cryptococcus neoformans virulence

Yu, Chendi Katherine, Stephenson, Christina J., Villamor, Tristan C., Dyba, Taylor G., Schulz, Benjamin L. and Fraser, James A. (2025). Deciphering the functions of Spt20 in the SAGA complex: Implications for Cryptococcus neoformans virulence. Life Sciences, 368 123509, 123509. doi: 10.1016/j.lfs.2025.123509

Deciphering the functions of Spt20 in the SAGA complex: Implications for Cryptococcus neoformans virulence

2024

Journal Article

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans

Floyd, Holly E. E., Kavanagh, Angela M., Lowe, Gabrielle J., Amado, Maite, Fraser, James A., Blaskovich, Mark A. T., Elliott, Alysha G. and Zuegg, Johannes (2024). Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans. Scientific Reports, 14 (1) 23407. doi: 10.1038/s41598-024-74068-2

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans

2024

Journal Article

A Framework for the Communication Capabilities of scientists

Dyba, Taylor G., Rowland, Susan L. and Fraser, James A. (2024). A Framework for the Communication Capabilities of scientists. International Journal of Science Education, Part B, 14 (4), 1-19. doi: 10.1080/21548455.2024.2412265

A Framework for the Communication Capabilities of scientists

2024

Journal Article

Experiences from supporting undergraduate students learning to communicate science: a comment on Lewenstein & Baram-Tsabari, 2022

Dyba, Taylor G., Rowland, Susan L. and Fraser, James A. (2024). Experiences from supporting undergraduate students learning to communicate science: a comment on Lewenstein & Baram-Tsabari, 2022. International Journal of Science Education, Part B, 14 (4), 470-472. doi: 10.1080/21548455.2024.2412264

Experiences from supporting undergraduate students learning to communicate science: a comment on Lewenstein & Baram-Tsabari, 2022

2024

Journal Article

A chimeric ORF fusion phenotypic reporter for Cryptococcus neoformans

Phillips-Rose, Louis S., Yu, Chendi K., West, Nicholas P. and Fraser, James A. (2024). A chimeric ORF fusion phenotypic reporter for Cryptococcus neoformans. Journal of Fungi, 10 (8) 567. doi: 10.3390/jof10080567

A chimeric ORF fusion phenotypic reporter for Cryptococcus neoformans

2023

Journal Article

SAGA complex subunit Hfi1 is important in the stress response and pathogenesis of Cryptococcus neoformans

Yu, Chendi K., Stephenson, Christina J., Villamor, Tristan C., Dyba, Taylor G., Schulz, Benjamin L. and Fraser, James A. (2023). SAGA complex subunit Hfi1 is important in the stress response and pathogenesis of Cryptococcus neoformans. Journal of Fungi, 9 (12) 1198, 1-16. doi: 10.3390/jof9121198

SAGA complex subunit Hfi1 is important in the stress response and pathogenesis of Cryptococcus neoformans

2023

Journal Article

Structure-activity relationships of bensulfuron methyl and its derivatives as novel agents against drug-resistant Candida auris

Sun, Xue-Wen, Liu, Yixuan, Wang, Xiaofang, Li, Hao-Ran, Lin, Xin, Tang, Jin-Yin, Xu, Qing, Agnew-Francis, Kylie A., Fraser, James A., Sun, Zhi-Juan, Guddat, Luke W. and Wang, Jian-Guo (2023). Structure-activity relationships of bensulfuron methyl and its derivatives as novel agents against drug-resistant Candida auris. Chemical Biology & Drug Design, 103 (1) e14364, e14364. doi: 10.1111/cbdd.14364

Structure-activity relationships of bensulfuron methyl and its derivatives as novel agents against drug-resistant Candida auris

2022

Conference Publication

Investigating the link between pleomorphism and virulence in <i>Cryptococcus</i>

Fernandes, Kenya, Fraser, James and Carter, Dee (2022). Investigating the link between pleomorphism and virulence in Cryptococcus. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/mmy/myac072.P192

Investigating the link between pleomorphism and virulence in <i>Cryptococcus</i>

2022

Journal Article

AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans

Wizrah, Maha S. I., Chua, Sheena M. H., Luo, Zhenyao, Manik, Mohammad K., Pan, Mengqi, Whyte, Jessica M. L., Robertson, Avril A. B., Kappler, Ulrike, Kobe, Bostjan and Fraser, James A. (2022). AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans. Journal of Biological Chemistry, 298 (10) 102453, 102453. doi: 10.1016/j.jbc.2022.102453

AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans

2022

Journal Article

Lineages derived from Cryptococcus neoformans type strain H99 support a link between the capacity to be pleomorphic and virulence

Fernandes, Kenya E., Fraser, James A. and Carter, Dee A. (2022). Lineages derived from Cryptococcus neoformans type strain H99 support a link between the capacity to be pleomorphic and virulence. mBio, 13 (2). doi: 10.1128/mbio.00283-22

Lineages derived from Cryptococcus neoformans type strain H99 support a link between the capacity to be pleomorphic and virulence

2022

Journal Article

Identification and characterisation of sPEPs in Cryptococcus neoformans

Erpf, Paige E., Chua, Sheena M.H., Phung, Toan K., Kerr, Edward D., Rothnagel, Joseph A., Schulz, Benjamin L. and Fraser, James A. (2022). Identification and characterisation of sPEPs in Cryptococcus neoformans. Fungal Genetics and Biology, 160 103688, 103688. doi: 10.1016/j.fgb.2022.103688

Identification and characterisation of sPEPs in Cryptococcus neoformans

2021

Journal Article

Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads

Low, Y. S., Garcia, M. D., Lonhienne, T., Fraser, J. A., Schenk, G. and Guddat, L. W. (2021). Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads. Scientific Reports, 11 (1) 21055. doi: 10.1038/s41598-021-00349-9

Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads

2021

Journal Article

Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets

Chua, Sheena M. H., Wizrah, Maha S. I., Luo, Zhenyao, Lim, Bryan Y. J., Kappler, Ulrike, Kobe, Bostjan and Fraser, James A. (2021). Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets. Journal of Biological Chemistry, 297 (4) 101091. doi: 10.1016/j.jbc.2021.101091

Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets

2020

Journal Article

Surveying purine biosynthesis across the domains of life unveils promising drug targets in pathogens

Chua, Sheena M. H. and Fraser, James A. (2020). Surveying purine biosynthesis across the domains of life unveils promising drug targets in pathogens. Immunology and Cell Biology, 98 (10), 819-831. doi: 10.1111/imcb.12389

Surveying purine biosynthesis across the domains of life unveils promising drug targets in pathogens

2020

Journal Article

Herbicides that target acetohydroxyacid synthase are potent inhibitors of the growth of drug resistant Candida auris

Agnew-Francis, Kylie A., Tang, Yu Cheng, Lin, Xin, Low, Yu Shang, Wun, Shun Jie, Kuo, Andy, Elias, S. M. A. Sayeed Ibn, Lonhienne, Thierry G., Condon, Nicholas, Pimentel, Bruna Natalia Alves da Silva, Vergani, Carlos, Smith, Maree T., Fraser, James A., Williams, Craig M. and Guddat, Luke W (2020). Herbicides that target acetohydroxyacid synthase are potent inhibitors of the growth of drug resistant Candida auris. ACS infectious diseases, 6 (11) acsinfecdis.0c00229, 2901-2912. doi: 10.1021/acsinfecdis.0c00229

Herbicides that target acetohydroxyacid synthase are potent inhibitors of the growth of drug resistant Candida auris

2020

Journal Article

Structures of fungal and plant acetohydroxyacid synthases

Lonhienne, Thierry, Low, Yu Shang, Garcia, Mario D., Croll, Tristan, Gao, Yan, Wang, Quan, Brillault, Lou, Williams, Craig M., Fraser, James A., McGeary, Ross P., West, Nicholas P., Landsberg, Michael J., Rao, Zihe, Schenk, Gerhard and Guddat, Luke W. (2020). Structures of fungal and plant acetohydroxyacid synthases. Nature, 586 (7828), 317-321+. doi: 10.1038/s41586-020-2514-3

Structures of fungal and plant acetohydroxyacid synthases

2020

Journal Article

Broadening the spectrum of fluorescent protein tools for use in the encapsulated human fungal pathogen Cryptococcus neoformans

Spencer, Garrick W.K., Chua, Sheena M.H., Erpf, Paige E., Wizrah, Maha S.I., Dyba, Taylor G., Condon, Nicholas D. and Fraser, James A. (2020). Broadening the spectrum of fluorescent protein tools for use in the encapsulated human fungal pathogen Cryptococcus neoformans. Fungal Genetics and Biology, 138 103365, 103365. doi: 10.1016/j.fgb.2020.103365

Broadening the spectrum of fluorescent protein tools for use in the encapsulated human fungal pathogen Cryptococcus neoformans

2020

Journal Article

Kalparinol, a Salvialane (Isodaucane) sesquiterpenoid derived from native Australian dysphania species that suggests a putative biogenetic link to zerumbone

Tan, Yuen Ping, Savchenko, Andrei I., Agnew-Francis, Kylie A., Boyle, Glen M., Bernhardt, Paul V., Fraser, James A. and Williams, Craig M. (2020). Kalparinol, a Salvialane (Isodaucane) sesquiterpenoid derived from native Australian dysphania species that suggests a putative biogenetic link to zerumbone. Journal of Natural Products, 83 (5) acs.jnatprod.9b01039, 1473-1479. doi: 10.1021/acs.jnatprod.9b01039

Kalparinol, a Salvialane (Isodaucane) sesquiterpenoid derived from native Australian dysphania species that suggests a putative biogenetic link to zerumbone

2020

Journal Article

Humulene diepoxides from the Australian arid zone herb Dysphania: assignment of aged hops constituents

Tan, Yuen Ping, Agnew‐Francis, Kylie A., Hofmann, Julian, Savchenko, Andrei I., Lafontaine, Scott R., Boyle, Glen M., Bernhardt, Paul V., Fraser, James A., Shellhammer, Thomas H. and Williams, Craig M. (2020). Humulene diepoxides from the Australian arid zone herb Dysphania: assignment of aged hops constituents. Chemistry: A European Journal, 26 (7) chem.201904420, 1653-1660. doi: 10.1002/chem.201904420

Humulene diepoxides from the Australian arid zone herb Dysphania: assignment of aged hops constituents

2019

Journal Article

Regulatory mechanism of the atypical AP-1-like transcription factor Yap1 in Cryptococcus neoformans

So, Yee-Seul, Maeng, Shinae, Yang, Dong-Hoon, Kim, Hyelim, Lee, Kyung-Tae, Yu, Seong-Ryong, Tenor, Jennifer L., Giri, Vinay K., Toffaletti, Dena L., Arras, Samantha, Fraser, James A., Perfect, John R. and Bahn, Yong-Sun (2019). Regulatory mechanism of the atypical AP-1-like transcription factor Yap1 in Cryptococcus neoformans. mSphere, 4 (6) e00785, e00785-19. doi: 10.1128/mSphere.00785-19

Regulatory mechanism of the atypical AP-1-like transcription factor Yap1 in Cryptococcus neoformans