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2014 Conference Publication The H99 family tree: variation in the common laboratory reference strains of Cryptococcus neoformans var. grubii characterised through whole-genome sequencingOrmerod, K. L., Byrnes, E. J., III, Wood, I. A., Lodge, J. K., Heitman, J. and Fraser, J. A. (2014). The H99 family tree: variation in the common laboratory reference strains of Cryptococcus neoformans var. grubii characterised through whole-genome sequencing. 9th International Conference on Cryptococcus and Cryptococcosis, Amsterdam, The Netherlands, 15-19 May 2014. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/myc.12196 |
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2014 Conference Publication Purine biosynthetic enzymes as antifungal drug targetsBlundell, R. B., Arras, S. D. M., Williams, S. J. and Fraser, J. A. (2014). Purine biosynthetic enzymes as antifungal drug targets. 9th International Conference on Cryptococcus and Cryptococcosis, Amsterdam, The Netherlands, 15-19 May 2014. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/myc.12196 |
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2013 Journal Article Balancing stability and flexibility within the genome of the pathogen Cryptococcus neoformansOrmerod, Kate L. and Fraser, James A. (2013). Balancing stability and flexibility within the genome of the pathogen Cryptococcus neoformans. PLoS Pathogens, 9 (12) e1003764, 1-4. doi: 10.1371/journal.ppat.1003764 |
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2013 Journal Article Purification, crystallization and preliminary X-ray analysis of adenylosuccinate synthetase from the fungal pathogen Cryptococcus neoformansBlundell, Ross D., Williams, Simon J., Morrow, Carl A., Ericsson, Daniel J., Kobe, Bostjan and Fraser, James A. (2013). Purification, crystallization and preliminary X-ray analysis of adenylosuccinate synthetase from the fungal pathogen Cryptococcus neoformans. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69 (Pt. 9), 1033-1036. doi: 10.1107/S1744309113021921 |
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2013 Journal Article Secondary metabolites of the sponge-derived fungus Acremonium persicinumSuciati, Fraser, James A., Lambert, Lynette K., Pierens, Gregory K., Bernhardt, Paul V. and Garson, Mary J. (2013). Secondary metabolites of the sponge-derived fungus Acremonium persicinum. Journal of Natural Products, 76 (8), 1432-1440. doi: 10.1021/np4002114 |
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2013 Journal Article Nitrogen regulation of virulence in clinically prevalent fungal pathogensLee, I. Russel, Morrow, Carl A. and Fraser, James A. (2013). Nitrogen regulation of virulence in clinically prevalent fungal pathogens. FEMS Microbiology Letters, 345 (2), 77-84. doi: 10.1111/1574-6968.12181 |
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2013 Journal Article Is the nickel-dependent urease complex of Cryptococcus the pathogen's Achilles' heel?Morrow, Carl A. and Fraser, James A. (2013). Is the nickel-dependent urease complex of Cryptococcus the pathogen's Achilles' heel?. MBio, 4 (4) e00408-13, e00408-13.1-e00408-13.3. doi: 10.1128/mBio.00408-13 |
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2013 Journal Article Reactive oxygen species homeostasis and virulence of the fungal pathogen Cryptococcus neoformans requires an intact proline catabolism pathwayLee, I. Russel, Lui, Edmund Y. L., Chow, Eve W. L., Arras, Samantha D. M., Morrow, Carl A. and Fraser, James A. (2013). Reactive oxygen species homeostasis and virulence of the fungal pathogen Cryptococcus neoformans requires an intact proline catabolism pathway. Genetics, 194 (2), 421-U199. doi: 10.1534/genetics.113.150326 |
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2013 Journal Article Characterization of the complete uric acid degradation pathway in the fungal pathogen Cryptococcus neoformansLee, I. Russel, Yang, Liting, Sebetso, Gaseene, Allen, Rebecca, Doan, Thi H. N., Blundell, Ross, Lui, Edmund Y. L., Morrow, Carl A. and Fraser, James A. (2013). Characterization of the complete uric acid degradation pathway in the fungal pathogen Cryptococcus neoformans. PLoS ONE, 8 (5) e64292, e64292.1-e64292.13. doi: 10.1371/journal.pone.0064292 |
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2013 Journal Article Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and VirulenceOrmerod, Kate L., Morrow, Carl A., Chow, Eve W. L., Lee, I. Russel, Arras, Samantha D. M., Schirra, Horst Joachim, Cox, Gary M., Fries, Bettina C. and Fraser, James A. (2013). Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence. G3: Genes, Genomes, Genetics, 3 (4), 675-686. doi: 10.1534/g3.113.005660 |
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2013 Journal Article Ploidy variation as an adaptive mechanism in human pathogenic fungiMorrow, Carl A. and Fraser, James A. (2013). Ploidy variation as an adaptive mechanism in human pathogenic fungi. Seminars in Cell and Developmental Biology, 24 (4), 339-346. doi: 10.1016/j.semcdb.2013.01.008 |
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2013 Journal Article Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthaseLee, Yu-Ting, Cui, Chang-Jun, Chow, Eve W. L., Pue, Nason, Lonhienne, Thierry, Wang, Jian-Guo, Fraser, James A. and Guddat, Luke W. (2013). Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. Journal of Medicinal Chemistry, 56 (1), 210-219. doi: 10.1021/jm301501k |
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2012 Journal Article De novo GTP biosynthesis is critical for virulence of the fungal pathogen cryptococcus neoformansMorrow, Carl A., Valkov, Eugene, Stamp, Anna, Chow, Eve W. L., Lee, I. Russel, Wronski, Ania, Williams, Simon J., Hill, Justine M., Djordjevic, Julianne T., Kappler, Ulrke, Kobe, Bostjan and Fraser, James A. (2012). De novo GTP biosynthesis is critical for virulence of the fungal pathogen cryptococcus neoformans. PLoS Pathogens, 8 (10) e1002957, e1002957. doi: 10.1371/journal.ppat.1002957 |
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2012 Journal Article Complexity of chromatin folding is captured by the strings and binders switch modelBarbieri, Mariano, Chotalia, Mita, Fraser, James, Lavitas, Liron-Mark, Dostie, Josée, Pombo, Ana and Nicodemi, Mario (2012). Complexity of chromatin folding is captured by the strings and binders switch model. Proceedings of the National Academy of Sciences of the United States of America, 109 (40), 16173-16178. doi: 10.1073/pnas.1204799109 |
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2012 Journal Article Characterization of an Nmr homolog that modulates gata factor-mediated nitrogen metabolite repression in Cryptococcus neoformansLee, I. Russel, Lim, Jonathan W. C., Ormerod, Kate L., Morrow, Carl A. and Fraser, James A. (2012). Characterization of an Nmr homolog that modulates gata factor-mediated nitrogen metabolite repression in Cryptococcus neoformans. PLoS One, 7 (3) e32585, e32585.1-e32585.15. doi: 10.1371/journal.pone.0032585 |
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2012 Journal Article A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulenceMorrow, Carl A., Lee, I. Russell, Chow, Eve W. L., Ormerod, Kate L., Goldinger, Anita, Byrnes III, Edmond J., Nielsen, Kirsten, Heitman, Joseph, Schirra, Horst Joachim and Fraser, James A. (2012). A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence. mBio, 3 (2) e00310-11, e00310.1-e00310.11. doi: 10.1128/mBio.00310-11 |
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2012 Journal Article Discovery of a Modified Tetrapolar Sexual Cycle in Cryptococcus amylolentus and the Evolution of MAT in the Cryptococcus Species ComplexFindley, Keisha, Sun, Sheng, Fraser, James A., Hsueh, Yen-Ping, Averette, Anna Floyd, Li, Wenjun, Dietrich, Fred S. and Heitman, Joseph (2012). Discovery of a Modified Tetrapolar Sexual Cycle in Cryptococcus amylolentus and the Evolution of MAT in the Cryptococcus Species Complex. PLoS Genetics, 8 (2) e1002528, e1002528-1-e1002528-19. doi: 10.1371/journal.pgen.1002528 |
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2012 Conference Publication The Relationship Between Conduction Velocity and Atrial Arrhythmogenicity under Conditions of Altered Ca2+Homeostasis in RyR2-P2328S Murine HeartsKing, James Harmsworth, Zhang, Yanmin, Huang, Chris and Fraser, James (2012). The Relationship Between Conduction Velocity and Atrial Arrhythmogenicity under Conditions of Altered Ca2+Homeostasis in RyR2-P2328S Murine Hearts. 56th Annual Meeting of the Biophysical-Society, San Diego Ca, Feb 25-29, 2012. CAMBRIDGE: CELL PRESS. |
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2012 Journal Article Microevolution of Cryptococcus neoformans driven by massive tandem gene amplificationChow, Eve W. L., Morrow, Carl A., Djordjevic, Julianne T., Wood, Ian A. and Fraser, James A. (2012). Microevolution of Cryptococcus neoformans driven by massive tandem gene amplification. Molecular Biology and Evolution, 29 (8), 1987-2000. doi: 10.1093/molbev/mss066 |
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2011 Journal Article A diverse population of Cryptococcus gattii molecular type VGIII in Southern Californian HIV/AIDS patientsByrnes, Edmond J., Li, Wenjun, Ren, Ping, Lewit, Yonathan, Voelz, Kerstin, Fraser, James A., Dietrich, Fred S., May, Robin C., Chatuverdi, Sudha, Chatuverdi, Vishnu and Heitman, Joseph (2011). A diverse population of Cryptococcus gattii molecular type VGIII in Southern Californian HIV/AIDS patients. PLoS Pathogens, 7 (9) e1002205, 134-1. doi: 10.1371/journal.ppat.1002205 |
