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2020

Journal Article

Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies

Nazir, Yasir, Saeed, Aamer, Rafiq, Muhammad, Afzal, Samina, Ali, Anser, Latif, Muhammad, Zuegg, Johannes, Hussein, Waleed M., Fercher, Christian, Barnard, Ross T., Cooper, Matthew A., Blaskovich, Mark A.T., Ashraf, Zaman and Ziora, Zyta M. (2020). Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies. Bioorganic and Medicinal Chemistry Letters, 30 (1) 126722, 1-5. doi: 10.1016/j.bmcl.2019.126722

Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies

2019

Book

Peptide synthesis: methods and protocols

Waleed Hussein, Mariusz Skwarczynski and Istvan Toth eds. (2019). Peptide synthesis: methods and protocols. New York, NY USA: Humana New York. doi: 10.1007/978-1-0716-0227-0

Peptide synthesis: methods and protocols

2019

Journal Article

Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice

Ssemaganda, Aloysious, Giddam, Ashwini Kumar, Low, Leanne M., Liu, Xue Q., Ho, Mei-Fong, Zaman, Mehfuz, Hussein, Waleed M., Skwarczynski, Mariusz, Toth, Istvan, Stanisic, Danielle I. and Good, Michael F. (2019). Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice. Vaccine, 38 (6), 1494-1504. doi: 10.1016/j.vaccine.2019.11.063

Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice

2019

Journal Article

Synthesis, evaluation and structural investigations of potent purple acid phosphatase inhibitors as drug leads for osteoporosis

Feder, Daniel, Kan, Meng-Wei, Hussein, Waleed M., Guddat, Luke W., Schenk, Gerhard and McGeary, Ross P. (2019). Synthesis, evaluation and structural investigations of potent purple acid phosphatase inhibitors as drug leads for osteoporosis. European Journal of Medicinal Chemistry, 182 111611, 111611. doi: 10.1016/j.ejmech.2019.111611

Synthesis, evaluation and structural investigations of potent purple acid phosphatase inhibitors as drug leads for osteoporosis

2019

Journal Article

Cholic acid-based delivery system for vaccine candidates against Group A Streptococcus

Azuar, Armira, Zhao, Lili, Hei, Tsui Ting, Nevagi, Reshma J., Bartlett, Stacey, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Skwarczynski, Mariusz (2019). Cholic acid-based delivery system for vaccine candidates against Group A Streptococcus. ACS Medicinal Chemistry Letters, 10 (9) acsmedchemlett.9b00239, 1253-1259. doi: 10.1021/acsmedchemlett.9b00239

Cholic acid-based delivery system for vaccine candidates against Group A Streptococcus

2019

Journal Article

Peptide-based targeted polymeric nanoparticles for siRNA delivery

Hussein, Waleed M., Cheong, Yee S., Liu, Chang, Liu, Genan, Begum, Anjuman Ara, Attallah, Maria Adly, Moyle, Peter Michael, Torchilin, Vladimir, Smith, Roger and Toth, Istvan (2019). Peptide-based targeted polymeric nanoparticles for siRNA delivery. Nanotechnology, 30 (41) 415604, 415604. doi: 10.1088/1361-6528/ab313d

Peptide-based targeted polymeric nanoparticles for siRNA delivery

2019

Journal Article

Recent advances in the development of peptide vaccines and their delivery systems against Group A Streptococcus

Azuar, Armira, Jin, Wanli , Mukaida, Saori, Hussein, Waleed , Toth, Istvan and Skwarczynski, Mariusz (2019). Recent advances in the development of peptide vaccines and their delivery systems against Group A Streptococcus. Vaccines, 7 (3) 58, 58. doi: 10.3390/vaccines7030058

Recent advances in the development of peptide vaccines and their delivery systems against Group A Streptococcus

2019

Journal Article

Self-assembly of trimethyl chitosan and poly(anionic amino acid)-peptide antigen conjugate to produce a potent self-adjuvanting nanovaccine delivery system

Nevagi, Reshma J., Dai, Wei, Khalil, Zeinab G., Hussein, Waleed M., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2019). Self-assembly of trimethyl chitosan and poly(anionic amino acid)-peptide antigen conjugate to produce a potent self-adjuvanting nanovaccine delivery system. Bioorganic and Medicinal Chemistry, 27 (14), 3082-3088. doi: 10.1016/j.bmc.2019.05.033

Self-assembly of trimethyl chitosan and poly(anionic amino acid)-peptide antigen conjugate to produce a potent self-adjuvanting nanovaccine delivery system

2019

Journal Article

Structure-activity relationship of group A streptococcus lipopeptide vaccine candidates in trimethyl chitosan-based self-adjuvanting delivery system

Nevagi, Reshma J., Dai, Wei, Khalil, Zeinab G., Hussein, Waleed M., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2019). Structure-activity relationship of group A streptococcus lipopeptide vaccine candidates in trimethyl chitosan-based self-adjuvanting delivery system. European Journal of Medicinal Chemistry, 179, 100-108. doi: 10.1016/j.ejmech.2019.06.047

Structure-activity relationship of group A streptococcus lipopeptide vaccine candidates in trimethyl chitosan-based self-adjuvanting delivery system

2019

Journal Article

Advances in targeted gene delivery

Begum, Anjuman A., Toth, Istvan, Hussein, Waleed M. and Moyle, Peter Michael (2019). Advances in targeted gene delivery. Current Drug Delivery, 16 (7), 588-608. doi: 10.2174/1567201816666190529072914

Advances in targeted gene delivery

2019

Journal Article

Synthesis and evaluation of novel purple acid phosphatase inhibitors

Hussein, Waleed M., Feder, Daniel, Schenk, Gerhard, Guddat, Luke W. and McGeary, Ross P. (2019). Synthesis and evaluation of novel purple acid phosphatase inhibitors. MedChemComm, 10 (1), 61-71. doi: 10.1039/c8md00491a

Synthesis and evaluation of novel purple acid phosphatase inhibitors

2019

Conference Publication

Development of polymer-based nanoparticulate intranasal lipopeptide vaccine constructs against group A streptococcus

Nevagi, Reshma Jayprakash, Dai, Wei, Khalil, Zeinab, Hussein, Waleed, Capon, Robert, Skwarczynski, Mariusz and Toth, Istvan (2019). Development of polymer-based nanoparticulate intranasal lipopeptide vaccine constructs against group A streptococcus. National Meeting of the American Chemical Society (ACS), Orlando, FL, United States, 31 March - 4 April, 2019. Washington, DC, United States: American Chemical Society.

Development of polymer-based nanoparticulate intranasal lipopeptide vaccine constructs against group A streptococcus

2019

Conference Publication

Carbohydrates in vaccine development

Aljohani, Salwa, Hussein, Waleed M., Toth, Istvan and Simerska, Pavla (2019). Carbohydrates in vaccine development. Controlled Release Asia Meeting, Singapore, 24-25 September, 2018. Sharjah, United Arab Emirates: Bentham Science Publishers. doi: 10.2174/1567201816666190702153612

Carbohydrates in vaccine development

2018

Journal Article

Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer

Khongkow, Mattaka, Liu, Tzu-yu, Bartlett, Stacey, Hussein, Waleed M., Nevagi, Reshma, Jia, Zhongfan, Monteiro, Michael J., Wells, James, Ruktanonchai, Uracha Rungsardthong, Skwarczynski, Mariusz and Toth, Istvan (2018). Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer. Precision Nanomedicine, 1 (3), 183-193. doi: 10.33218/prnano1(3).181003.1

Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer

2018

Journal Article

Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics

Hussein, Waleed M., Feder, Daniel, Schenk, Gerhard, Guddat, Luke W. and McGeary, Ross P. (2018). Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics. European Journal of Medicinal Chemistry, 157, 462-479. doi: 10.1016/j.ejmech.2018.08.004

Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics

2018

Journal Article

Investigating the affinity of poly tert-butyl acrylate toward Toll-Like Receptor 2

Hussein, Waleed M., Choi, Phil M., Zhang, Cheng, Sierecki, Emma, Johnston, Wayne, Jia, Zhongfan, Monteiro, Michael J., Skwarczynski, Mariusz, Gambin, Yann and Toth, Istvan (2018). Investigating the affinity of poly tert-butyl acrylate toward Toll-Like Receptor 2. AIMS Allergy and Immunology, 2 (3), 141-147. doi: 10.3934/allergy.2018.3.141

Investigating the affinity of poly tert-butyl acrylate toward Toll-Like Receptor 2

2018

Journal Article

Polyglutamic acid-trimethyl chitosan-based intranasal peptide nano-vaccine induces potent immune responses against group A streptococcus

Nevagi, Reshma J., Khalil, Zeinab G., Hussein, Waleed M., Powell, Jessica, Batzloff, Michael R., Capon, Robert J., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2018). Polyglutamic acid-trimethyl chitosan-based intranasal peptide nano-vaccine induces potent immune responses against group A streptococcus. Acta Biomaterialia, 80, 278-287. doi: 10.1016/j.actbio.2018.09.037

Polyglutamic acid-trimethyl chitosan-based intranasal peptide nano-vaccine induces potent immune responses against group A streptococcus

2017

Journal Article

Fluorinated lipids conjugated to peptide antigens do not induce immune responses against cervical cancer

Hussein, Waleed M., Mukaida, Saori, Liu, Tzu-Yu, Toth, Istvan and Skwarczynski, Mariusz (2017). Fluorinated lipids conjugated to peptide antigens do not induce immune responses against cervical cancer. Vaccination Research Open Journal, 1 (1), 39-44. doi: 10.17140/VROJ-1-107

Fluorinated lipids conjugated to peptide antigens do not induce immune responses against cervical cancer

2017

Journal Article

Synthesis, characterization and immunological evaluation of self-adjuvanting group a streptococcal vaccine candidates bearing various lipidic adjuvanting moieties

Fagan, Vincent, Hussein, Waleed M., Su, Mei, Gidda, Ashwini K., Batzloff, Michael R., Good, Michael F., Toth, Istvan and Simerska, Pavla (2017). Synthesis, characterization and immunological evaluation of self-adjuvanting group a streptococcal vaccine candidates bearing various lipidic adjuvanting moieties. ChemBioChem, 18 (6), 545-553. doi: 10.1002/cbic.201600639

Synthesis, characterization and immunological evaluation of self-adjuvanting group a streptococcal vaccine candidates bearing various lipidic adjuvanting moieties

2017

Journal Article

Comparison of fluorinated and nonfluorinated lipids in self-adjuvanting delivery systems for peptide-based vaccines

Hussein, Waleed M., Mukaida, Saori, Azmi, Fazren, Bartlett, Stacey, Olivier, Celine, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2017). Comparison of fluorinated and nonfluorinated lipids in self-adjuvanting delivery systems for peptide-based vaccines. ACS Medicinal Chemistry Letters, 8 (2), 227-232. doi: 10.1021/acsmedchemlett.6b00453

Comparison of fluorinated and nonfluorinated lipids in self-adjuvanting delivery systems for peptide-based vaccines