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2025

Journal Article

Evaluation of novel single-dose vaccine candidates against gonadotropin-releasing hormone (GnRH) in mice

Shalash, Ahmed O., Wang, Wanyi, Xia, Yihui, Hussein, Waleed M., Bashiri, Sahra, D'Occhio, Michael J., Stephenson, Rachel J., Skwarczynski, Mariusz and Toth, Istvan (2025). Evaluation of novel single-dose vaccine candidates against gonadotropin-releasing hormone (GnRH) in mice. Vaccine, 53 127092. doi: 10.1016/j.vaccine.2025.127092

Evaluation of novel single-dose vaccine candidates against gonadotropin-releasing hormone (GnRH) in mice

2025

Journal Article

Influence of component structural arrangement on cholesterol-antigen conjugate immunogenicity and antisera bactericidal activity against group A Streptococcus

Skwarczynski, Mariusz, Alharbi, Nedaa, Nahar, Ummey J., Shalash, Ahmed O., Azuar, Armira, Koirala, Prashamsa, Khisty, Shefali J., Wang, Jingwen, Marasini, Nirmal, Hussein, Waleed M., Khalil, Zeinab G. and Toth, Istvan (2025). Influence of component structural arrangement on cholesterol-antigen conjugate immunogenicity and antisera bactericidal activity against group A Streptococcus. Bioorganic Chemistry, 157 108248, 108248-157. doi: 10.1016/j.bioorg.2025.108248

Influence of component structural arrangement on cholesterol-antigen conjugate immunogenicity and antisera bactericidal activity against group A Streptococcus

2025

Journal Article

A synthetic cyclic peptide for promoting antigen presentation and immune activation

Zhang, Jiahui, Madge, Harrison Y. R., Mahmoud, Asmaa, Lu, Lantian, Wang, Wanyi, Huang, Wenbin, Koirala, Prashamsa, Gonzalez Cruz, Jazmina L., Kong, Wei Yang, Bashiri, Sahra, Shalash, Ahmed O., Hussein, Waleed M., Khalil, Zeinab G., Wells, James W., Toth, Istvan and Stephenson, Rachel J. (2025). A synthetic cyclic peptide for promoting antigen presentation and immune activation. NPJ Vaccines, 10 (1) 9, 9-1. doi: 10.1038/s41541-024-01050-4

A synthetic cyclic peptide for promoting antigen presentation and immune activation

2024

Journal Article

Total synthesis of talarolide A and atrop-Talarolide A: hydroxamate H-bond bridge stabilization of cyclic peptide conformers invokes non-canonical atropisomerism

Hussein, Waleed M., Zhu, Yuxuan, Salim, Angela A. and Capon, Robert J. (2024). Total synthesis of talarolide A and atrop-Talarolide A: hydroxamate H-bond bridge stabilization of cyclic peptide conformers invokes non-canonical atropisomerism. Marine Drugs, 22 (10) 454. doi: 10.3390/md22100454

Total synthesis of talarolide A and atrop-Talarolide A: hydroxamate H-bond bridge stabilization of cyclic peptide conformers invokes non-canonical atropisomerism

2024

Journal Article

Self-assembled monovalent lipidated mannose ligand as a standalone nanoadjuvant

Nahar, Ummey J., Wang, Jingwen, Shalash, Ahmed O., Lu, Lantian, Islam, Md. T., Alharbi, Nedaa, Koirala, Prashamsa, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2024). Self-assembled monovalent lipidated mannose ligand as a standalone nanoadjuvant. Vaccine, 42 (23) 126060. doi: 10.1016/j.vaccine.2024.06.027

Self-assembled monovalent lipidated mannose ligand as a standalone nanoadjuvant

2024

Journal Article

Australian marine and terrestrial Streptomyces-derived surugamides, and synthetic analogs, and their ability to inhibit Dirofilaria immitis (heartworm) motility

Wu, Taizong, Hussein, Waleed M., Samarasekera, Kaumadi, Zhu, Yuxuan, Khalil, Zeinab G., Jin, Shengbin, Bruhn, David F., Moreno, Yovany, Salim, Angela A. and Capon, Robert J. (2024). Australian marine and terrestrial Streptomyces-derived surugamides, and synthetic analogs, and their ability to inhibit Dirofilaria immitis (heartworm) motility. Marine Drugs, 22 (7) 312. doi: 10.3390/md22070312

Australian marine and terrestrial Streptomyces-derived surugamides, and synthetic analogs, and their ability to inhibit Dirofilaria immitis (heartworm) motility

2024

Journal Article

Cholesterol as an inbuilt immunoadjuvant for a lipopeptide vaccine against group A Streptococcus infection

Alharbi, Nedaa, Shalash, Ahmed O., Koirala, Prashamsa, Boer, Jennifer C., Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2024). Cholesterol as an inbuilt immunoadjuvant for a lipopeptide vaccine against group A Streptococcus infection. Journal of Colloid and Interface Science, 663, 43-52. doi: 10.1016/j.jcis.2024.02.134

Cholesterol as an inbuilt immunoadjuvant for a lipopeptide vaccine against group A Streptococcus infection

2024

Journal Article

Pullenvalenes A–D: Nitric oxide-mediated transcriptional activation (NOMETA) enables discovery of triterpene aminoglycosides from Australian Termite nest-derived fungi

Dewa, Amila Agampodi, Khalil, Zeinab G., Hussein, Waleed M., Jin, Shengbin, Wang, Yanan, Cruz-Morales, Pablo and Capon, Robert J. (2024). Pullenvalenes A–D: Nitric oxide-mediated transcriptional activation (NOMETA) enables discovery of triterpene aminoglycosides from Australian Termite nest-derived fungi. Journal of Natural Products, 87 (4), 935-947. doi: 10.1021/acs.jnatprod.3c01233

Pullenvalenes A–D: Nitric oxide-mediated transcriptional activation (NOMETA) enables discovery of triterpene aminoglycosides from Australian Termite nest-derived fungi

2024

Conference Publication

Regulation of 20a-hydroxysteroid dehydrogenase expression in term pregnant human myometrium

Paul, Marina, Barreda, Anna Paredes, Gregson, Amy, Kahl, Richard, King, Madeline, Hussein, Waleed M., Walker, Frederick R., Smith, Roger, Zakar, Tamas and Paul, Jonathan W. (2024). Regulation of 20a-hydroxysteroid dehydrogenase expression in term pregnant human myometrium. 71st Annual Meeting of the Society for Reproductive Investigation (SRI), Vancouver, BC, Canada, 12-16 March 2024. Heidelberg, Germany: Springer.

Regulation of 20a-hydroxysteroid dehydrogenase expression in term pregnant human myometrium

2024

Journal Article

Polymeric nanoparticles as oral and intranasal peptide vaccine delivery systems: the role of shape and conjugation

Koirala, Prashamsa, Shalash, Ahmed O., Chen, Sung-Po R., Faruck, Mohammad O., Wang, Jingwen, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2024). Polymeric nanoparticles as oral and intranasal peptide vaccine delivery systems: the role of shape and conjugation. Vaccines, 12 (2) 198, 1-14. doi: 10.3390/vaccines12020198

Polymeric nanoparticles as oral and intranasal peptide vaccine delivery systems: the role of shape and conjugation

2023

Journal Article

Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011

Salim, Angela A., Hussein, Waleed M., Dewapriya, Pradeep, Hoang, Huy N., Zhou, Yahao, Samarasekera, Kaumadi, Khalil, Zeinab G., Fairlie, David P. and Capon, Robert J. (2023). Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011. Marine Drugs, 21 (9) 487, 1-17. doi: 10.3390/md21090487

Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011

2023

Journal Article

Regulation of 20α-hydroxysteroid dehydrogenase expression in term pregnant human myometrium ex vivo

Paul, Marina, Barreda, Anna Paredes, Gregson, Amy, Kahl, Richard, King, Madeline, Hussein, Waleed M., Walker, Frederick R., Smith, Roger, Zakar, Tamas and Paul, Jonathan W. (2023). Regulation of 20α-hydroxysteroid dehydrogenase expression in term pregnant human myometrium ex vivo. Reproductive Sciences, 31 (1), 1-12. doi: 10.1007/s43032-023-01333-6

Regulation of 20α-hydroxysteroid dehydrogenase expression in term pregnant human myometrium ex vivo

2023

Journal Article

Activity relationship of poly(ethylenimine)-based liposomes as group A Streptococcus vaccine delivery systems

Jin, Shengbin, Zhang, Jiahui, Nahar, Ummey J., Huang, Wenbin, Alharbi, Nedaa A., Shalash, Ahmed O., Koirala, Prashamsa, Yang, Jieru, Kiong, Jolynn J. E., Khalil, Zeinab G., Capon, Robert J., Stephenson, Rachel J., Skwarczynski, Mariusz, Toth, Istvan and Hussein, Waleed M. (2023). Activity relationship of poly(ethylenimine)-based liposomes as group A Streptococcus vaccine delivery systems. ACS Infectious Diseases, 9 (8), 1570-1581. doi: 10.1021/acsinfecdis.3c00159

Activity relationship of poly(ethylenimine)-based liposomes as group A Streptococcus vaccine delivery systems

2023

Journal Article

Optimization of an α-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches

Feder, Daniel, Mohd-Pahmi, Siti Hajar, Adibi, Hadi, Guddat, Luke W., Schenk, Gerhard, McGeary, Ross P. and Hussein, Waleed M. (2023). Optimization of an α-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches. European Journal of Medicinal Chemistry, 254 115383, 1-19. doi: 10.1016/j.ejmech.2023.115383

Optimization of an α-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches

2023

Journal Article

Glyclauxins A–E: dimeric oxaphenalenone aminoglycosides from an Australian wasp nest-derived fungus Talaromyces sp. CMB-MW102

Samarasekera, Kaumadi, Hussein, Waleed M., Wu, Taizong, Salim, Angela A. and Capon, Robert J. (2023). Glyclauxins A–E: dimeric oxaphenalenone aminoglycosides from an Australian wasp nest-derived fungus Talaromyces sp. CMB-MW102. Journal of Natural Products, 86 (3), 517-525. doi: 10.1021/acs.jnatprod.2c01069

Glyclauxins A–E: dimeric oxaphenalenone aminoglycosides from an Australian wasp nest-derived fungus Talaromyces sp. CMB-MW102

2023

Journal Article

Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancer

Firdaus, Farrhana Z., Bartlett, Stacey, Hussein, Waleed M., Lu, Lantian, Wright, Quentin, Huang, Wenbin, Nahar, Ummey J., Yang, Jieru, Khongkow, Mattaka, Veitch, Margaret, Koirala, Prashamsa, Ruktanonchai, Uracha R., Monteiro, Michael J., Gonzalez Cruz, Jazmina L., Stephenson, Rachel J., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2023). Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancer. Pharmaceutics, 15 (2) 602, 1-15. doi: 10.3390/pharmaceutics15020602

Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancer

2023

Journal Article

The development of surface-modified liposomes as an intranasal delivery system for group A Streptococcus vaccines

Yang, Jieru, Boer, Jennifer C., Khongkow, Mattaka, Phunpee, Sarunya, Khalil, Zeinab G., Bashiri, Sahra, Deceneux, Cyril, Goodchild, Georgia, Hussein, Waleed M., Capon, Robert J., Ruktanonchai, Uracha, Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2023). The development of surface-modified liposomes as an intranasal delivery system for group A Streptococcus vaccines. Vaccines, 11 (2) 305. doi: 10.3390/vaccines11020305

The development of surface-modified liposomes as an intranasal delivery system for group A Streptococcus vaccines

2023

Journal Article

Polymeric nanoparticles as a self‐adjuvanting peptide vaccine delivery system: the role of shape

Koirala, Prashamsa, Chen, Sung‐Po R., Boer, Jennifer C., Khalil, Zeinab G., Deceneux, Cyril, Goodchild, Georgia, Lu, Lantian, Faruck, Mohammad Omer, Shalash, Ahmed O., Bashiri, Sahra, Capon, Robert J., Hussein, Waleed M., Monteiro, Michael J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2023). Polymeric nanoparticles as a self‐adjuvanting peptide vaccine delivery system: the role of shape. Advanced Functional Materials, 33 (12) 2209304, 2209304. doi: 10.1002/adfm.202209304

Polymeric nanoparticles as a self‐adjuvanting peptide vaccine delivery system: the role of shape

2023

Conference Publication

Pro-relaxation of myometrial phosphodiesterase expression by histone deacetylase inhibitors

Barreda, Anna Paredes, Ilicic, Marina, Zakar, Tamas, Gregson, Amy, Hussein, Waleed, Walker, Frederick R., Smith, Roger and Paul, Jonathan W. (2023). Pro-relaxation of myometrial phosphodiesterase expression by histone deacetylase inhibitors. 70th Annual Meeting of the Society for Reproductive Investigation (SRI), Brisbane, QLD, Australia, 21-25 March 2023. Heidelberg, Germany: Springer.

Pro-relaxation of myometrial phosphodiesterase expression by histone deacetylase inhibitors

2023

Journal Article

Polyphenylalanine as a self-adjuvanting delivery system for peptide-based vaccines: the role of peptide conformation

Skwarczynski, Mariusz, Zhao, Guangzu, Ozberk, Victoria, Giddam, Ashwini Kumar, Khalil, Zeinab G., Pandey, Manisha, Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Capon, Robert J., Good, Michael F. and Toth, Istvan (2023). Polyphenylalanine as a self-adjuvanting delivery system for peptide-based vaccines: the role of peptide conformation. Australian Journal of Chemistry, 76 (8), 429-436. doi: 10.1071/ch22167

Polyphenylalanine as a self-adjuvanting delivery system for peptide-based vaccines: the role of peptide conformation